TW200612918A - Lonidamine analogs - Google Patents
Lonidamine analogsInfo
- Publication number
- TW200612918A TW200612918A TW094126067A TW94126067A TW200612918A TW 200612918 A TW200612918 A TW 200612918A TW 094126067 A TW094126067 A TW 094126067A TW 94126067 A TW94126067 A TW 94126067A TW 200612918 A TW200612918 A TW 200612918A
- Authority
- TW
- Taiwan
- Prior art keywords
- lonidamine analogs
- lonidamine
- analogs
- bph
- cancer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/72—Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59283304P | 2004-07-29 | 2004-07-29 | |
| US59272304P | 2004-07-29 | 2004-07-29 | |
| US59966604P | 2004-08-05 | 2004-08-05 | |
| US64618805P | 2005-01-21 | 2005-01-21 | |
| US65170505P | 2005-02-09 | 2005-02-09 | |
| US66106705P | 2005-03-11 | 2005-03-11 | |
| US68308705P | 2005-05-19 | 2005-05-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200612918A true TW200612918A (en) | 2006-05-01 |
Family
ID=35787877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW094126067A TW200612918A (en) | 2004-07-29 | 2005-07-29 | Lonidamine analogs |
Country Status (2)
| Country | Link |
|---|---|
| TW (1) | TW200612918A (fr) |
| WO (1) | WO2006015263A2 (fr) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7514463B2 (en) * | 2004-08-20 | 2009-04-07 | University Of Kansas | Lonidamine analogues and their use in male contraception and cancer treatment |
| JP4318744B2 (ja) | 2005-03-31 | 2009-08-26 | ファイザー・プロダクツ・インク | シクロペンタピリジンおよびテトラヒドロキノリン誘導体 |
| AU2006263433B8 (en) | 2005-06-29 | 2011-06-09 | Immunogenesis, Inc. | Phosphoramidate alkylator prodrugs |
| BRPI0707945A2 (pt) | 2006-02-17 | 2011-05-17 | Pfizer Ltd | derivados de 3-deazapurina como modulares de tlr7 |
| US7501438B2 (en) | 2006-07-07 | 2009-03-10 | Forest Laboratories Holdings Limited | Pyridoimidazole derivatives |
| CN102850324A (zh) | 2006-08-07 | 2013-01-02 | 硬木药品公司 | 吲哚化合物 |
| JP5252636B2 (ja) | 2006-09-19 | 2013-07-31 | 第一三共株式会社 | ピラゾロピリミジン誘導体 |
| US7858645B2 (en) * | 2006-11-01 | 2010-12-28 | Hoffmann-La Roche Inc. | Indazole derivatives |
| DE102007026341A1 (de) | 2007-06-06 | 2008-12-11 | Merck Patent Gmbh | Benzoxazolonderivate |
| DE102007032507A1 (de) | 2007-07-12 | 2009-04-02 | Merck Patent Gmbh | Pyridazinonderivate |
| DE102007061963A1 (de) | 2007-12-21 | 2009-06-25 | Merck Patent Gmbh | Pyridazinonderivate |
| MX2010009462A (es) * | 2008-02-29 | 2010-09-24 | Pfizer | Derivados de indazol. |
| DE102008019907A1 (de) | 2008-04-21 | 2009-10-22 | Merck Patent Gmbh | Pyridazinonderivate |
| DE102008028905A1 (de) | 2008-06-18 | 2009-12-24 | Merck Patent Gmbh | 3-(3-Pyrimidin-2-yl-benzyl)-[1,2,4]triazolo[4,3-b]pyridazinderivate |
| DE102008037790A1 (de) | 2008-08-14 | 2010-02-18 | Merck Patent Gmbh | Bicyclische Triazolderivate |
| UA103646C2 (ru) | 2008-12-22 | 2013-11-11 | Мерк Патент Гмбх | Полиморфные формы 6-(1-метил-1h-пиразол-4-ил)-2-{3-[5-(2-морфолин-4-илетокси)-пиримидин-2-ил]-бензил}-2h-пиридазин-3-она и способ их получения (варианты) |
| SG173829A1 (en) | 2009-02-25 | 2011-09-29 | Daiichi Sankyo Co Ltd | Tricyclic pyrazolopyrimidine deritives |
| CA2809120C (fr) | 2010-08-23 | 2015-10-13 | Daiichi Sankyo Company, Limited | Derive pyrazolopyrimidine tricyclique sous forme cristalline |
| BR112013004258A2 (pt) | 2010-08-23 | 2016-08-02 | Daiichi Sankyo Co Ltd | cristal, composição farmacêutica, e, agente anticâncer |
| AR084433A1 (es) | 2010-12-22 | 2013-05-15 | Ironwood Pharmaceuticals Inc | Inhibidores de la faah y composiciones farmaceuticas que los contienen |
| JP6371284B2 (ja) | 2012-08-22 | 2018-08-08 | コーネル ユニヴァーシティー | ファスシンを阻害する方法 |
| BR112016018555B1 (pt) | 2014-02-13 | 2024-01-23 | Incyte Holdings Corporation | Ciclopropilaminas como inibidores de lsd1, seu uso, composição farmacêutica que os compreende e método de inibição de lsd1 |
| US9493442B2 (en) | 2014-02-13 | 2016-11-15 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| US9527835B2 (en) | 2014-02-13 | 2016-12-27 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| CN106164066B (zh) | 2014-02-13 | 2020-01-17 | 因赛特公司 | 作为lsd1抑制剂的环丙胺 |
| EP3107902B1 (fr) * | 2014-02-20 | 2021-04-07 | Cornell University Cornell Center For Technology, Enterprise & Commercialization ("CCTEC") | Composés et procédés d'inhibition de la fascine |
| TWI687419B (zh) | 2014-07-10 | 2020-03-11 | 美商英塞特公司 | 作為ｌｓｄ１抑制劑之咪唑并吡啶及咪唑并吡嗪 |
| TW201613925A (en) | 2014-07-10 | 2016-04-16 | Incyte Corp | Imidazopyrazines as LSD1 inhibitors |
| US9695167B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors |
| WO2016007727A1 (fr) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines et triazolopyrazines utilisables comme inhibiteurs de lsd1 |
| ES2757948T3 (es) | 2015-04-03 | 2020-04-30 | Incyte Corp | Compuestos heterocíclicos como inhibidores LSD1 |
| CN110402244B (zh) | 2015-08-12 | 2023-02-03 | 因赛特公司 | Lsd1抑制剂的盐 |
| CN108602775B (zh) * | 2016-01-14 | 2022-04-29 | 贝思以色列女会吏医学中心公司 | 肥大细胞调节剂及其用途 |
| WO2017121693A1 (fr) | 2016-01-15 | 2017-07-20 | Bayer Pharma Aktiengesellschaft | Thiazolamides et thiadiazolamides substitués et leur utilisation |
| US10166221B2 (en) | 2016-04-22 | 2019-01-01 | Incyte Corporation | Formulations of an LSD1 inhibitor |
| EP3564214B1 (fr) | 2018-05-04 | 2024-07-03 | Universita' Degli Studi G. D'annunzio Chieti - Pescara | Dérivés d'indazole en tant que modulateurs du système de cannabinoïdes |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
| EP3856176A4 (fr) | 2018-09-28 | 2022-05-04 | Acucela Inc. | Inhibiteurs de vap-1 |
| CN113164489A (zh) | 2018-09-28 | 2021-07-23 | 奥克塞拉有限公司 | Vap-1的抑制剂 |
| KR102241064B1 (ko) * | 2019-07-30 | 2021-04-16 | 부산대학교 산학협력단 | 신규한 인돌 유도체 및 이를 포함하는 염증성 질환 예방 또는 치료용 조성물 |
| JP2023541944A (ja) * | 2020-09-17 | 2023-10-04 | エサイエント ファーマシューティカルズ，インコーポレイティド | Ｍａｓ関連ｇタンパク質受容体ｘ４のモジュレーター、並びに関連製品及び方法 |
| WO2024109642A1 (fr) * | 2023-07-28 | 2024-05-30 | 常州大学 | UTILISATION D'UN COMPOSÉ BENZOAZACYCLIQUE EN TANT QUE MODULATEUR ALLOSTÉRIQUE D'UN β2-ADRÉNORÉCEPTEUR |
-
2005
- 2005-07-29 TW TW094126067A patent/TW200612918A/zh unknown
- 2005-07-29 WO PCT/US2005/027092 patent/WO2006015263A2/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006015263A3 (fr) | 2006-07-27 |
| WO2006015263A2 (fr) | 2006-02-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW200612918A (en) | Lonidamine analogs | |
| IL190796A0 (en) | Compositions and their uses for gene therapy of bone conditions | |
| MX2022009759A (es) | El uso de 1-(4-ciano-3-trifluorometil-fenil)-3-[7-(4-ciano-3-trifl uorometil-fenil)-6-tioxo-5-p-tolilo-5,7-diazaespiro[3.4]oct-8-ili deno]-tiourea. | |
| CA105195S (en) | Bottle | |
| SG148864A1 (en) | Methods of treating cancer and related methods | |
| TW200501960A (en) | Synergistic kits and compositions for treating cancer | |
| IL181629A0 (en) | Compositions and methods for the diagnosis and tretment of tumor | |
| SG170809A1 (en) | Diarylthiohydantoin compounds | |
| ZA200702973B (en) | Disubstituted pyrazolobenzodiazepines useful as inhibitors for CDK2 and angiogesis, and for the treatment of breast, colon, lung and prostate cancer | |
| CA115590S (en) | Back therapy device | |
| IL178012A0 (en) | Diphenyl-indol-2-on compounds and their use in the treatment of cancer | |
| AU2003212634A8 (en) | Compounds useful in the treatment of cancer | |
| SI1546182T1 (sl) | Sestavki in postopki za diagnozo in zdravljenje tumorja | |
| CA104143S (en) | Brush | |
| ZA200709542B (en) | Combination therapy in the treatment of cancer | |
| TW200605885A (en) | Multicyclic lonidamine analogs | |
| AU2006251169A8 (en) | Tetrahydropyridothiophenes for use in the treatment of cancer | |
| AU2006251167A8 (en) | Tetrahydropyridothiophenes for use in the treatment of cancer | |
| MX2007002277A (es) | Metodos para formar retinoides y usos de los mismos. | |
| NO20053903L (no) | Nukleotidlipidesterderivater. | |
| ATE469659T1 (de) | Stibogluconate-natrium und il-2 zur krebsbehandlung | |
| AU309683S (en) | Massaging belt | |
| EG24959A (en) | Indoles useful in the treatment of androgenreceptor related diseases. | |
| AU302605S (en) | Aquarium | |
| MXPA03002494A (es) | Metodo para reducir toxicidad de quimio terapias combinadas. |