TW200730500A - 4, 5-dihydro-(1H)-pyrazole derivatives as cannabinoid CB1 receptor modulators - Google Patents

4, 5-dihydro-(1H)-pyrazole derivatives as cannabinoid CB1 receptor modulators

Info

Publication number: TW200730500A
Authority: TW; Taiwan
Prior art keywords: compounds; cannabinoid; dihydro; receptor modulators; methods
Prior art date: 2005-12-20

Application number

TW095147172A

Other languages

English (en)

Chinese (zh)

Inventor

Josephus H M Lange

Van Der Neut

Bakker Wouter I Iwema

Van Vliet

Original Assignee

Solvay Pharm Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-12-20

Filing date

2006-12-15

Publication date

2007-08-16

2006-12-15 Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv

2007-08-16 Publication of TW200730500A publication Critical patent/TW200730500A/zh

Links

102000009132 CB1 Cannabinoid Receptor Human genes 0.000 title abstract 3
108010073366 CB1 Cannabinoid Receptor Proteins 0.000 title abstract 3
229930003827 cannabinoid Natural products 0.000 title abstract 2
239000003557 cannabinoid Substances 0.000 title abstract 2
MCGBIXXDQFWVDW-UHFFFAOYSA-N 4,5-dihydro-1h-pyrazole Chemical class C1CC=NN1 MCGBIXXDQFWVDW-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 4
238000000034 method Methods 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 2
UCIBGBIBKNEJNF-UHFFFAOYSA-N 2,3-dihydro-1h-pyrazole;4,5-dihydro-1h-pyrazole Chemical class C1CC=NN1.C1NNC=C1 UCIBGBIBKNEJNF-UHFFFAOYSA-N 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
102000005962 receptors Human genes 0.000 abstract 1
108020003175 receptors Proteins 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

TW095147172A 2005-12-20 2006-12-15 4, 5-dihydro-(1H)-pyrazole derivatives as cannabinoid CB1 receptor modulators TW200730500A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP05112482		2005-12-20

Publications (1)

Publication Number	Publication Date
TW200730500A true TW200730500A (en)	2007-08-16

Family

ID=35749602

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW095147172A TW200730500A (en)	2005-12-20	2006-12-15	4, 5-dihydro-(1H)-pyrazole derivatives as cannabinoid CB1 receptor modulators

Country Status (8)

Country	Link
CN (1)	CN101341127A (de)
AR (1)	AR058370A1 (de)
AT (1)	ATE500228T1 (de)
BR (1)	BRPI0620035A2 (de)
DE (1)	DE602006020489D1 (de)
SA (1)	SA06270469B1 (de)
TW (1)	TW200730500A (de)
ZA (1)	ZA200804926B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR079935A1 (es) *	2010-01-29	2012-02-29	Abbott Healthcare Products Bv	Sintesis de derivados de pirazolin carboxamidina sustituida
EP2661421A2 (de) *	2011-01-07	2013-11-13	Targacept, Inc.	Nichtkompetitive antagonisten des nikotinrezeptors
CN107417578B (zh) *	2017-08-23	2020-02-07	沈阳海诺威医药科技有限公司	N-(3,5-二甲基金刚烷-1-基)-n’-取代苯基脲类化合物及其制备方法和用途

2006
- 2006-12-15 TW TW095147172A patent/TW200730500A/zh unknown
- 2006-12-18 SA SA06270469A patent/SA06270469B1/ar unknown
- 2006-12-18 AR ARP060105577A patent/AR058370A1/es not_active Application Discontinuation
- 2006-12-19 DE DE602006020489T patent/DE602006020489D1/de active Active
- 2006-12-19 CN CNA2006800483547A patent/CN101341127A/zh active Pending
- 2006-12-19 BR BRPI0620035-4A patent/BRPI0620035A2/pt not_active IP Right Cessation
- 2006-12-19 AT AT06841437T patent/ATE500228T1/de not_active IP Right Cessation
2008
- 2008-06-05 ZA ZA200804926A patent/ZA200804926B/xx unknown

Also Published As

Publication number	Publication date
DE602006020489D1 (de)	2011-04-14
CN101341127A (zh)	2009-01-07
AR058370A1 (es)	2008-01-30
BRPI0620035A2 (pt)	2011-10-25
ATE500228T1 (de)	2011-03-15
SA06270469B1 (ar)	2010-07-25
ZA200804926B (en)	2009-04-29

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