TW232697B - - Google Patents

Info

Publication number: TW232697B
Authority: TW; Taiwan

Application number

TW081109304A

Other languages

Chinese (zh)

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-11-22

Filing date

1992-11-20

Publication date

1994-10-21

1992-11-20 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

1994-10-21 Application granted granted Critical

1994-10-21 Publication of TW232697B publication Critical patent/TW232697B/zh

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

TW081109304A 1991-11-22 1992-11-20 TW232697B (2)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US79614891A	1991-11-22	1991-11-22
US93619892A	1992-08-26	1992-08-26

Publications (1)

Publication Number	Publication Date
TW232697B true TW232697B (2)	1994-10-21

Family

ID=27121696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW081109304A TW232697B (2)	1991-11-22	1992-11-20

Country Status (17)

Country	Link
EP (1)	EP0641347A1 (2)
JP (1)	JPH07501078A (2)
CN (1)	CN1073946A (2)
AU (1)	AU661362B2 (2)
CA (1)	CA2123128A1 (2)
CZ (1)	CZ124494A3 (2)
FI (1)	FI942345A0 (2)
HU (1)	HUT67937A (2)
IL (1)	IL103817A0 (2)
MX (1)	MX9206628A (2)
NO (1)	NO941905L (2)
NZ (1)	NZ245207A (2)
PT (1)	PT101079A (2)
SI (1)	SI9200332A (2)
SK (1)	SK59294A3 (2)
TW (1)	TW232697B (2)
WO (1)	WO1993010127A1 (2)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
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US6825169B1 (en)	1991-10-22	2004-11-30	Trustees Of Tufts College	Inhibitors of dipeptidyl-aminopeptidase type IV
US5965532A (en) *	1996-06-28	1999-10-12	Trustees Of Tufts College	Multivalent compounds for crosslinking receptors and uses thereof
US6040145A (en)	1997-05-07	2000-03-21	Tufts University	Potentiation of the immune response
US6100234A (en)	1997-05-07	2000-08-08	Tufts University	Treatment of HIV
ATE357509T1 (de)	1997-09-29	2007-04-15	Point Therapeutics Inc	Stimulierung von hämatopoietischen zellen im vitro
IL139247A0 (en)	1998-05-04	2001-11-25	Point Therapeutics Inc	Hematopoietic stimulation
JP2002517401A (ja) *	1998-06-05	2002-06-18	ポイントセラピューティクス，インコーポレイテッド	環状ボロプロリン化合物
US6979697B1 (en)	1998-08-21	2005-12-27	Point Therapeutics, Inc.	Regulation of substrate activity
US6890904B1 (en)	1999-05-25	2005-05-10	Point Therapeutics, Inc.	Anti-tumor agents
EP1259246A2 (en) *	2000-02-25	2002-11-27	Novo Nordisk A/S	Use of dpp-iv inhibitors for the treatment of diabetes
WO2003063903A2 (en) *	2002-02-01	2003-08-07	Probiodrug Ag	Modulation of t lymphocytes using dp iv inhibitors
US7317109B2 (en)	2003-11-12	2008-01-08	Phenomix Corporation	Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
US7767828B2 (en)	2003-11-12	2010-08-03	Phenomix Corporation	Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
SG134333A1 (en) *	2003-11-12	2007-08-29	Phenomix Corp	Heterocyclic boronic acid compounds
US7576121B2 (en)	2003-11-12	2009-08-18	Phenomix Corporation	Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
WO2005049022A2 (en)	2003-11-17	2005-06-02	Novartis Ag	Use of dipeptidyl peptidase iv inhibitors
RU2766487C2 (ru)	2004-01-20	2022-03-15	Новартис Аг	Композиция и способ прямого прессования
TW200604137A (en)	2004-04-27	2006-02-01	Wyeth Corp	Coupling process for generating reactive boron-containing derivatives of n-substituted pyrrole-2-carbonitriles to produce biaryls
DOP2006000008A (es)	2005-01-10	2006-08-31	Arena Pharm Inc	Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
US7399869B2 (en)	2005-05-19	2008-07-15	Genentech, Inc.	Fibroblast activation protein inhibitor compounds and methods
US7825139B2 (en)	2005-05-25	2010-11-02	Forest Laboratories Holdings Limited (BM)	Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
CN1331835C (zh) *	2005-10-18	2007-08-15	武汉大学	光活性β－羟基酮的制备方法
JP5270369B2 (ja) *	2005-12-19	2013-08-21	タフツユニバーシティー／トラスティーズオブタフツカレッジ	ソフトプロテアーゼ抑制剤およびそのプロソフト型
US7833730B2 (en)	2006-04-11	2010-11-16	Arena Pharmaceuticals, Inc.	Methods of using GPR119 to identify compounds useful for increasing bone mass in an individual
PE20071221A1 (es)	2006-04-11	2007-12-14	Arena Pharm Inc	Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
EP2108960A1 (en)	2008-04-07	2009-10-14	Arena Pharmaceuticals, Inc.	Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
EP2730579A1 (en)	2008-06-17	2014-05-14	Millennium Pharmaceuticals, Inc.	Boronate ester compounds and pharmaceutical compositions thereof
AR077642A1 (es)	2009-07-09	2011-09-14	Arena Pharm Inc	Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
CA2795513A1 (en)	2010-04-06	2011-10-13	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
EP3323818A1 (en)	2010-09-22	2018-05-23	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
US20140018371A1 (en)	2011-04-01	2014-01-16	Arena Pharmaceuticals, Inc.	Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
WO2012145361A1 (en)	2011-04-19	2012-10-26	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
US20140051714A1 (en)	2011-04-22	2014-02-20	Arena Pharmaceuticals, Inc.	Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
US20140038889A1 (en)	2011-04-22	2014-02-06	Arena Pharmaceuticals, Inc.	Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
WO2012170702A1 (en)	2011-06-08	2012-12-13	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2013055910A1 (en)	2011-10-12	2013-04-18	Arena Pharmaceuticals, Inc.	Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2014074668A1 (en)	2012-11-08	2014-05-15	Arena Pharmaceuticals, Inc.	Modulators of gpr119 and the treatment of disorders related thereto
US9523687B2 (en)	2014-02-28	2016-12-20	Institut Pasteur	Levels of CXCL 10/IP-10 forms and soluble CD26/DPPIV activity as early predictive biomarkers for HIV/SIV associated mucosal inflammation and progression towards AIDS
MA39964A (fr)	2014-05-20	2015-11-26	Millennium Pharm Inc	Inhibiteurs du protéasome contenant du bore destinés à être utilisés après une thérapie contre le cancer primaire
EA201791982A1 (ru)	2015-03-09	2020-02-17	Интекрин Терапьютикс, Инк.	Способы лечения неалкогольной жировой болезни печени и/или липодистрофии
WO2018162722A1 (en)	2017-03-09	2018-09-13	Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke	Dpp-4 inhibitors for use in treating bone fractures
JP2020515639A (ja)	2017-04-03	2020-05-28	コヒラス・バイオサイエンシズ・インコーポレイテッド	進行性核上性麻痺の処置のためのＰＰＡＲγアゴニスト
CN108047257B (zh) *	2017-12-17	2020-03-13	沧州普瑞东方科技有限公司	一种手性n-boc-吡咯烷-2-硼酸的制备工艺
CN111741939B (zh) *	2018-02-20	2026-04-17	大塚制药株式会社	制备4-二羟硼基苯丙氨酸的方法
CN110452258B (zh) *	2019-09-03	2021-01-01	上海馨远医药科技有限公司	一种二肽缬氨酸硼脯氨酸盐的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4935493A (en) *	1987-10-06	1990-06-19	E. I. Du Pont De Nemours And Company	Protease inhibitors
EP0528858B1 (en) *	1990-04-14	1997-01-22	New England Medical Center Hospitals, Inc.	Inhibitors of dipeptidyl-aminopeptidase type iv
GB9017694D0 (en) *	1990-08-13	1990-09-26	Sandoz Ltd	Improvements in or relating to organic chemistry

1992
- 1992-11-18 MX MX9206628A patent/MX9206628A/es unknown
- 1992-11-19 PT PT101079A patent/PT101079A/pt not_active Application Discontinuation
- 1992-11-19 SI SI19929200332A patent/SI9200332A/sl unknown
- 1992-11-19 SK SK592-94A patent/SK59294A3/sk unknown
- 1992-11-19 AU AU31368/93A patent/AU661362B2/en not_active Expired - Fee Related
- 1992-11-19 CZ CZ941244A patent/CZ124494A3/cs unknown
- 1992-11-19 CA CA002123128A patent/CA2123128A1/en not_active Abandoned
- 1992-11-19 WO PCT/US1992/009845 patent/WO1993010127A1/en not_active Ceased
- 1992-11-19 JP JP5509442A patent/JPH07501078A/ja active Pending
- 1992-11-19 HU HU9401350A patent/HUT67937A/hu unknown
- 1992-11-19 EP EP92925238A patent/EP0641347A1/en not_active Withdrawn
- 1992-11-20 NZ NZ24520792A patent/NZ245207A/en unknown
- 1992-11-20 TW TW081109304A patent/TW232697B/zh active
- 1992-11-20 IL IL103817A patent/IL103817A0/xx unknown
- 1992-11-23 CN CN92113215A patent/CN1073946A/zh active Pending
1994
- 1994-05-20 NO NO941905A patent/NO941905L/no unknown
- 1994-05-20 FI FI942345A patent/FI942345A0/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
CN1073946A (zh)	1993-07-07
AU661362B2 (en)	1995-07-20
NO941905L (no)	1994-07-14
FI942345A7 (fi)	1994-05-20
HUT67937A (en)	1995-05-29
FI942345A0 (fi)	1994-05-20
AU3136893A (en)	1993-06-15
EP0641347A1 (en)	1995-03-08
SK59294A3 (en)	1995-02-08
CA2123128A1 (en)	1993-05-27
CZ124494A3 (en)	1995-07-12
MX9206628A (es)	1993-05-01
IL103817A0 (en)	1993-04-04
NO941905D0 (no)	1994-05-20
NZ245207A (en)	1994-07-26
PT101079A (pt)	1994-02-28
WO1993010127A1 (en)	1993-05-27
JPH07501078A (ja)	1995-02-02
HU9401350D0 (en)	1994-08-29
SI9200332A (en)	1993-06-30

Publication	Publication Date	Title
TW232697B (2)	1994-10-21
DE4291016T1 (2)	1993-05-13
DE4292034T1 (2)	1993-06-03
DK0520893T3 (2)	1997-02-10
DE4291684T1 (2)	1993-05-13
DE4292014T1 (2)	1993-06-03
DK0549782T3 (2)	1997-03-10
DK0511526T3 (2)	1992-11-04
DK0538124T3 (2)	1997-02-10
ECSM91540U (2)	1992-01-07
DK132791D0 (2)	1991-07-09
ECSM91576U (2)	1992-05-25
ECSM91558U (2)	1992-03-27
ECSM91555U (2)	1992-03-18
ECSM91550U (2)	1992-04-10
ECSM91536U (2)	1991-12-19
ECSM91528U (2)	1991-11-04
ECSDI910053S (2)	1992-06-03
ECSDI910048S (2)	1992-06-03
CN3009777S (2)	1991-06-05
CN3009751S (2)	1991-06-05
CN3009788S (2)	1991-06-05
EP0499478A3 (2)	1994-02-16
AU7921191A (2)	1991-10-17
AU7825991A (2)	1991-11-07