TW426516B - An oral pharmaceutical composition in solid dispersion containing water-insoluble tricyclic compounds - Google Patents

An oral pharmaceutical composition in solid dispersion containing water-insoluble tricyclic compounds Download PDF

Info

Publication number: TW426516B
Authority: TW; Taiwan
Prior art keywords: group; hydrogen atom; hydroxy; alkyl; pharmaceutical composition
Prior art date: 1996-12-06

Application number

TW086118225A

Other languages

English (en)

Chinese (zh)

Inventor

Takehisa Hata

Yuji Tokunaga

Fumio Shimojo

Takeo Hirose

Sumihisa Kimura

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-06

Filing date

1997-12-04

Publication date

2001-03-21

1997-12-04 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

2001-03-21 Application granted granted Critical

2001-03-21 Publication of TW426516B publication Critical patent/TW426516B/zh

Links

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239000008203 oral pharmaceutical composition Substances 0.000 title 1
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TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
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JYKSTGLAIMQDRA-UHFFFAOYSA-N tetraglycerol Chemical compound OCC(O)CO.OCC(O)CO.OCC(O)CO.OCC(O)CO JYKSTGLAIMQDRA-UHFFFAOYSA-N 0.000 description 1
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KJAMZCVTJDTESW-UHFFFAOYSA-N tiracizine Chemical compound C1CC2=CC=CC=C2N(C(=O)CN(C)C)C2=CC(NC(=O)OCC)=CC=C21 KJAMZCVTJDTESW-UHFFFAOYSA-N 0.000 description 1
JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
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125000001425 triazolyl group Chemical group 0.000 description 1
125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Transplantation (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

TW086118225A 1996-12-06 1997-12-04 An oral pharmaceutical composition in solid dispersion containing water-insoluble tricyclic compounds TW426516B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP32661896		1996-12-06

Publications (1)

Publication Number	Publication Date
TW426516B true TW426516B (en)	2001-03-21

Family

ID=18189823

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW086118225A TW426516B (en)	1996-12-06	1997-12-04	An oral pharmaceutical composition in solid dispersion containing water-insoluble tricyclic compounds

Country Status (17)

Country	Link
US (1)	US6346537B1 (fr)
EP (1)	EP0943327B1 (fr)
JP (1)	JP4284706B2 (fr)
KR (1)	KR20000057242A (fr)
CN (1)	CN1149979C (fr)
AR (1)	AR008927A1 (fr)
AT (1)	ATE367150T1 (fr)
AU (1)	AU726451B2 (fr)
BR (1)	BR9713866A (fr)
CA (1)	CA2274485C (fr)
DE (1)	DE69737936T2 (fr)
ES (1)	ES2286835T3 (fr)
HU (1)	HU228680B1 (fr)
RU (1)	RU2197226C2 (fr)
TW (1)	TW426516B (fr)
WO (1)	WO1998024418A1 (fr)
ZA (1)	ZA9710927B (fr)

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JP2010515753A (ja)	2007-01-10	2010-05-13	ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム	肺内送達用免疫抑制剤組成物の送達の増強
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HUE033011T2 (hu)	2007-05-30	2017-11-28	Veloxis Pharmaceuticals As	Takrolimuszt tartalmazó napi egyszeri orális dózisforma
US12083103B2 (en)	2007-05-30	2024-09-10	Veloxis Pharmaceuticals, Inc.	Tacrolimus for improved treatment of transplant patients
TW200932240A (en)	2007-10-25	2009-08-01	Astellas Pharma Inc	Pharmaceutical composition containing lipophilic substance which inhibits IL-2 production
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1997
- 1997-12-04 TW TW086118225A patent/TW426516B/zh not_active IP Right Cessation
- 1997-12-04 ZA ZA9710927A patent/ZA9710927B/xx unknown
- 1997-12-05 ES ES97946111T patent/ES2286835T3/es not_active Expired - Lifetime
- 1997-12-05 HU HU0000587A patent/HU228680B1/hu not_active IP Right Cessation
- 1997-12-05 BR BR9713866-5A patent/BR9713866A/pt not_active Application Discontinuation
- 1997-12-05 RU RU99114776/14A patent/RU2197226C2/ru not_active IP Right Cessation
- 1997-12-05 AU AU51369/98A patent/AU726451B2/en not_active Ceased
- 1997-12-05 KR KR1019990704614A patent/KR20000057242A/ko not_active Ceased
- 1997-12-05 CA CA002274485A patent/CA2274485C/fr not_active Expired - Fee Related
- 1997-12-05 AR ARP970105735A patent/AR008927A1/es active IP Right Grant
- 1997-12-05 CN CNB971816808A patent/CN1149979C/zh not_active Expired - Fee Related
- 1997-12-05 US US09/308,672 patent/US6346537B1/en not_active Expired - Lifetime
- 1997-12-05 WO PCT/JP1997/004452 patent/WO1998024418A1/fr not_active Ceased
- 1997-12-05 EP EP97946111A patent/EP0943327B1/fr not_active Expired - Lifetime
- 1997-12-05 AT AT97946111T patent/ATE367150T1/de not_active IP Right Cessation
- 1997-12-05 DE DE69737936T patent/DE69737936T2/de not_active Expired - Lifetime
- 1997-12-05 JP JP52545598A patent/JP4284706B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2274485A1 (fr)	1998-06-11
AU726451B2 (en)	2000-11-09
DE69737936D1 (de)	2007-08-30
ATE367150T1 (de)	2007-08-15
HU228680B1 (en)	2013-05-28
BR9713866A (pt)	2000-03-14
HUP0000587A1 (hu)	2000-09-28
AR008927A1 (es)	2000-02-23
AU5136998A (en)	1998-06-29
US6346537B1 (en)	2002-02-12
KR20000057242A (ko)	2000-09-15
CA2274485C (fr)	2008-02-05
ZA9710927B (en)	1998-06-15
JP4284706B2 (ja)	2009-06-24
CN1245424A (zh)	2000-02-23
EP0943327A1 (fr)	1999-09-22
HUP0000587A3 (en)	2001-12-28
ES2286835T3 (es)	2007-12-01
WO1998024418A1 (fr)	1998-06-11
EP0943327A4 (fr)	2003-06-25
EP0943327B1 (fr)	2007-07-18
DE69737936T2 (de)	2007-12-06
CN1149979C (zh)	2004-05-19
RU2197226C2 (ru)	2003-01-27

Legal Events

Date	Code	Title	Description
2001-07-24	GD4A	Issue of patent certificate for granted invention patent
2015-12-21	MM4A	Annulment or lapse of patent due to non-payment of fees

Publication	Publication Date	Title
TW426516B (en)	2001-03-21	An oral pharmaceutical composition in solid dispersion containing water-insoluble tricyclic compounds
TW200306867A (en)	2003-12-01	Sustained-release pharmaceutical composition (II)
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AU2016213722B2 (en)	2018-05-24	Solid dispersion of rifaximin
ES2376238T3 (es)	2012-03-12	Composiciones de liberación modificada comprendiendo tacrolimus.
JPWO1998024418A1 (ja)	2000-04-11	医薬組成物
KR20130100381A (ko)	2013-09-10	피르페니돈 및 약학적으로 허용가능한 부형제의 캡슐 제제
BRPI0414000B1 (pt)	2019-11-05	composição farmacêutica sólida oral de liberação prolongada contendo tacrolimus na forma de uma dispersão sólida, forma de dosagem, e, uso da composição farmacêutica
BRPI0212922B1 (pt)	2018-03-13	Composição farmacêutica na forma de um comprimido dispersável compreendendo uma dispersão sólida de 40-o-(2-hidroxietil)-rapamicina, seu processo de preparação e uso da dita composição
JP2022511374A (ja)	2022-01-31	Ｖａｐ－１の阻害剤
TW201040179A (en)	2010-11-16	Compositions and uses therof
CA2628630A1 (fr)	2007-05-24	Compositions d'inhibiteurs de lipoxygenase
JP2022511371A (ja)	2022-01-31	Ｖａｐ－１の阻害剤
TW202104225A (zh)	2021-02-01	原肌球蛋白相關激酶（ｔｒｋ）抑制劑之醫藥調配物
KR20210125994A (ko)	2021-10-19	비정질 스파르센탄 조성물
KR20170056574A (ko)	2017-05-23	알펠리십을 포함하는 제약 조성물
KR100525275B1 (ko)	2005-11-02	시알산 유도체를 함유하는 고체분산체
WO1998046268A1 (fr)	1998-10-22	Composition medicamenteuse
CA3220152A1 (fr)	2022-12-15	Compositions d'apilimod stabilisees et leurs utilisations
EA015715B1 (ru)	2011-10-31	Твердая дисперсия, фармацевтическая композиция, включающая такую дисперсию, способ ее получения и применение для предотвращения и лечения заболеваний, связанных с бензодиазепиновыми рецепторами периферического типа
EP4054613A1 (fr)	2022-09-14	Compositions de protection intestinale comprenant de l'acide boswellique
EP4637723A1 (fr)	2025-10-29	Formulations de bezuclastinib
MXPA99005044A (en)	2000-01-01	Medicinal composition
HK1038023B (en)	2005-08-05	Solid dispersion containing sialic acid derivative
HK1150766A (en)	2012-01-13	Pharmaceutical compositions comprising colloidal silicon dioxide