UA100248C2 - Heterocyclic compound and pharmaceutical composition thereof - Google Patents

Heterocyclic compound and pharmaceutical composition thereof

Info

Publication number: UA100248C2
Authority: UA; Ukraine
Prior art keywords: group; heterocyclic ring; heterocyclic compound; hydrogen atom; pharmaceutical composition
Prior art date: 2007-10-30

Application number

Other languages

English (en)

Russian (ru)

Ukrainian (uk)

Inventor

Такумі Суміда

Фудзіо Табуса

Казуо Секігуті

Такесі Кодама

Коіті Ясумура

Ютака Кодзіма

Масаакі Мотояма

Кеісуке Міядзіма

Кендзі Йосіда

Кеізо Кан

Макото САКАМОТО

Хідекі Такасу

Такасі Накагава

Наото Охі

Ясуо Харада

Норіказу Хасімото

Хіронорі Мацуяма

Масатосі Ііда

Сігеказу Фудзіта

Тає Фукусіма

Original Assignee

Оцука Фармасьютікал Ко., Лтд.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-30

Filing date

2008-10-29

Publication date

2012-12-10

2008-10-29 Application filed by Оцука Фармасьютікал Ко., Лтд. filed Critical Оцука Фармасьютікал Ко., Лтд.

2012-12-10 Publication of UA100248C2 publication Critical patent/UA100248C2/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Ophthalmology & Optometry (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Vascular Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Immunology (AREA)
Pulmonology (AREA)
Hematology (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

UAA201006444 2007-10-30 2008-10-29 Heterocyclic compound and pharmaceutical composition thereof UA100248C2 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2007281601		2007-10-30
JP2007336157		2007-12-27
PCT/JP2008/070153 WO2009057811A2 (en)	2007-10-30	2008-10-29	Heterocyclic compound and pharmaceutical composition thereof

Publications (1)

Publication Number	Publication Date
UA100248C2 true UA100248C2 (en)	2012-12-10

Family

ID=40474791

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UAA201006444 UA100248C2 (en)	2007-10-30	2008-10-29	Heterocyclic compound and pharmaceutical composition thereof

Country Status (28)

Country	Link
US (1)	US8551999B2 (da)
EP (1)	EP2207773B1 (da)
JP (1)	JP5236002B2 (da)
KR (1)	KR20100092469A (da)
CN (2)	CN103224488A (da)
AR (1)	AR069065A1 (da)
AU (1)	AU2008319719B2 (da)
BR (1)	BRPI0819232A2 (da)
CA (1)	CA2703240A1 (da)
CL (1)	CL2008003265A1 (da)
CO (1)	CO6210724A2 (da)
CY (1)	CY1113812T1 (da)
DK (1)	DK2207773T3 (da)
ES (1)	ES2390710T3 (da)
HR (1)	HRP20120748T1 (da)
IL (1)	IL204942A0 (da)
MX (1)	MX2010004893A (da)
MY (1)	MY148482A (da)
NZ (1)	NZ584573A (da)
PE (1)	PE20090949A1 (da)
PL (1)	PL2207773T3 (da)
PT (1)	PT2207773E (da)
RU (1)	RU2010121857A (da)
SI (1)	SI2207773T1 (da)
TW (1)	TWI440638B (da)
UA (1)	UA100248C2 (da)
WO (1)	WO2009057811A2 (da)
ZA (1)	ZA201002547B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8188277B2 (en)	2004-08-06	2012-05-29	Otsuka Pharmaceutical Co., Ltd.	Aromatic compounds for suppressing the generation of collagen
EP1957073B1 (en) *	2005-12-05	2014-04-23	Otsuka Pharmaceutical Co., Ltd.	Medicinal drug
UA95978C2 (ru) *	2006-10-02	2011-09-26	Оцука Фармас'Ютікел Ко., Лтд.	Ингибитор активации stat3/5
JO3265B1 (ar)	2008-12-09	2018-09-16	Novartis Ag	مثبطات بيريديلوكسى اندولات vegf-r2 واستخدامها لعلاج المرض
JP5688918B2 (ja) *	2009-04-28	2015-03-25	大塚製薬株式会社	医薬組成物
EP2947073B1 (en)	2009-10-22	2019-04-03	Fibrotech Therapeutics Pty Ltd	Fused ring analogues of anti-fibrotic agents
PH12012501532A1 (en) *	2010-01-29	2012-10-22	Otsuka Pharma Co Ltd	Di-substituted pyridine derivatives as anticancers
AU2013211888B2 (en)	2012-01-26	2017-08-31	Angion Biomedica Corp.	Antifibrotic compounds and uses thereof
ES2791534T3 (es)	2012-03-01	2020-11-04	Allergan Inc	Derivados de benzofuran-2-sulfonamida como moduladores del receptor de quimiocinas
AR094929A1 (es)	2013-02-28	2015-09-09	Bristol Myers Squibb Co	Derivados de fenilpirazol como inhibidores potentes de rock1 y rock2
EP2961746B1 (en)	2013-02-28	2018-01-03	Bristol-Myers Squibb Company	Phenylpyrazole derivatives as potent rock1 and rock2 inhibitors
EP3577103A1 (en)	2017-02-03	2019-12-11	Certa Therapeutics Pty Ltd.	Anti-fibrotic compounds
CN108721621B (zh) *	2017-04-14	2022-03-01	中国科学院上海高等研究院	抑制肝纤维化的小分子化合物及应用
CN108033918B (zh) *	2017-12-28	2020-12-25	西安欧得光电材料有限公司	一种光电材料中间体2-氯-4-苯基苯并[h]喹唑啉的合成方法
CN112300145B (zh) *	2019-07-31	2023-07-21	上海宇耀生物科技有限公司	一类靶向stat3双功能磷酸化位点的三芳香环类化合物及其应用
JP2023175057A (ja) *	2020-10-29	2023-12-12	クミアイ化学工業株式会社	縮合ヘテロ環誘導体及びそれを有効成分として含有する除草剤
WO2024199167A1 (zh) *	2023-03-27	2024-10-03	上海宇耀生物科技有限公司	三芳香环类衍生物的盐、其晶型、制备方法和用途
CN116715657B (zh) *	2023-04-19	2025-07-11	河南省锐达医药科技有限公司	一种二芳基乙炔类化合物、其制备方法及应用
CN116768864B (zh) *	2023-06-25	2025-08-01	河南省锐达医药科技有限公司	一种哌嗪吲哚酰胺类化合物、其制备方法及应用
CN118772123B (zh) *	2024-06-14	2025-09-16	河南省锐达医药科技有限公司	一种哌嗪-1-甲基吲哚-2-甲酰胺衍生物、其制备方法及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR015733A1 (es) *	1998-03-25	2001-05-16	Otsuka Pharma Co Ltd	DERIVADO DE PIRIDINA, EL PRODUCTO Y LA COMPOSICIoN FARMACEUTICA QUE CONTIENE DICHO DERIVADO.
JP2001089412A (ja) *	1999-09-22	2001-04-03	Otsuka Pharmaceut Co Ltd	ベンゼン誘導体またはその医薬的に許容される塩
JP2001089450A (ja) *	1999-09-22	2001-04-03	Otsuka Pharmaceut Co Ltd	ピリジン誘導体含有医薬製剤
KR100600550B1 (ko) *	2000-10-20	2006-07-13	에자이 가부시키가이샤	질소 함유 방향환 유도체

2008
- 2008-10-22 TW TW097140442A patent/TWI440638B/zh not_active IP Right Cessation
- 2008-10-28 AR ARP080104696A patent/AR069065A1/es unknown
- 2008-10-29 DK DK08845000.2T patent/DK2207773T3/da active
- 2008-10-29 JP JP2010530682A patent/JP5236002B2/ja not_active Expired - Fee Related
- 2008-10-29 MY MYPI2010001885A patent/MY148482A/en unknown
- 2008-10-29 PT PT08845000T patent/PT2207773E/pt unknown
- 2008-10-29 RU RU2010121857/04A patent/RU2010121857A/ru unknown
- 2008-10-29 EP EP08845000A patent/EP2207773B1/en not_active Not-in-force
- 2008-10-29 KR KR1020107011932A patent/KR20100092469A/ko not_active Ceased
- 2008-10-29 AU AU2008319719A patent/AU2008319719B2/en not_active Ceased
- 2008-10-29 SI SI200830740T patent/SI2207773T1/sl unknown
- 2008-10-29 PL PL08845000T patent/PL2207773T3/pl unknown
- 2008-10-29 WO PCT/JP2008/070153 patent/WO2009057811A2/en not_active Ceased
- 2008-10-29 CN CN2013100900890A patent/CN103224488A/zh active Pending
- 2008-10-29 NZ NZ584573A patent/NZ584573A/en not_active IP Right Cessation
- 2008-10-29 UA UAA201006444 patent/UA100248C2/xx unknown
- 2008-10-29 US US12/740,684 patent/US8551999B2/en not_active Expired - Fee Related
- 2008-10-29 BR BRPI0819232A patent/BRPI0819232A2/pt not_active IP Right Cessation
- 2008-10-29 CN CN200880114249A patent/CN101842367A/zh active Pending
- 2008-10-29 PE PE2008001846A patent/PE20090949A1/es not_active Application Discontinuation
- 2008-10-29 ES ES08845000T patent/ES2390710T3/es active Active
- 2008-10-29 MX MX2010004893A patent/MX2010004893A/es active IP Right Grant
- 2008-10-29 HR HRP20120748AT patent/HRP20120748T1/hr unknown
- 2008-10-29 CA CA2703240A patent/CA2703240A1/en not_active Abandoned
- 2008-10-30 CL CL2008003265A patent/CL2008003265A1/es unknown
2010
- 2010-04-08 IL IL204942A patent/IL204942A0/en unknown
- 2010-04-12 ZA ZA2010/02547A patent/ZA201002547B/en unknown
- 2010-05-14 CO CO10057752A patent/CO6210724A2/es active IP Right Grant
2012
- 2012-09-28 CY CY20121100896T patent/CY1113812T1/el unknown

Also Published As

Publication number	Publication date
CN103224488A (zh)	2013-07-31
US8551999B2 (en)	2013-10-08
JP5236002B2 (ja)	2013-07-17
NZ584573A (en)	2012-05-25
TWI440638B (zh)	2014-06-11
EP2207773B1 (en)	2012-07-11
AR069065A1 (es)	2009-12-23
WO2009057811A3 (en)	2009-07-09
CY1113812T1 (el)	2016-07-27
DK2207773T3 (da)	2012-09-10
RU2010121857A (ru)	2011-12-10
CA2703240A1 (en)	2009-05-07
JP2011502115A (ja)	2011-01-20
SI2207773T1 (sl)	2012-09-28
WO2009057811A2 (en)	2009-05-07
IL204942A0 (en)	2010-11-30
PL2207773T3 (pl)	2012-11-30
BRPI0819232A2 (pt)	2016-11-01
ZA201002547B (en)	2011-08-31
AU2008319719A1 (en)	2009-05-07
CO6210724A2 (es)	2010-10-20
TW200922932A (en)	2009-06-01
PT2207773E (pt)	2012-10-09
US20100261720A1 (en)	2010-10-14
CL2008003265A1 (es)	2010-02-05
MX2010004893A (es)	2010-05-19
AU2008319719B2 (en)	2013-12-12
PE20090949A1 (es)	2009-07-13
CN101842367A (zh)	2010-09-22
EP2207773A2 (en)	2010-07-21
HRP20120748T1 (hr)	2012-10-31
KR20100092469A (ko)	2010-08-20
MY148482A (en)	2013-04-30
ES2390710T3 (es)	2012-11-15

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MX2010008361A (es)	2010-08-30	Derivados de arilamida oxazepinopirimidona sustituidos.
MX2012003988A (es)	2012-07-23	Nuevos inhibidores de desacetilasas de histonas basados simultaneamente en 1h-pirroles trisustituidos y en espciadores aromaticos y heteroaromaticos.
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MY169179A (en)	2019-02-25	Novel piperidine compound or salt thereof
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MX2011009423A (es)	2011-09-28	Compuesto de piperazina capaz de inhibir prostaglandina d sintasa.
MX2009012380A (es)	2009-12-03	Compuestos de heteroarilamida pirimidona.
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EA201170097A1 (ru)	2011-08-30	Замещенные трициклические производные против нейродегенеративных заболеваний
MY164789A (en)	2018-01-30	Heterocyclic compounds for treating or preventing disorders caused by reduced neurotransmission of serotonin, norephnephrine or dopamine
PT2513115E (pt)	2013-12-19	Antibióticos tricíclicos
GB0501964D0 (en)	2005-03-09	Chemical compounds
WO2009130469A8 (en)	2010-12-09	Dna-pk inhibitors
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