UA105648C2 - Екструдати з голчатими активними речовинами - Google Patents

Екструдати з голчатими активними речовинами

Info

Publication number
UA105648C2
UA105648C2 UAA201108386A UAA201108386A UA105648C2 UA 105648 C2 UA105648 C2 UA 105648C2 UA A201108386 A UAA201108386 A UA A201108386A UA A201108386 A UAA201108386 A UA A201108386A UA 105648 C2 UA105648 C2 UA 105648C2
Authority
UA
Ukraine
Prior art keywords
extrudates
spicular
active substances
active substance
pharmaceutically active
Prior art date
Application number
UAA201108386A
Other languages
English (en)
Russian (ru)
Inventor
Венката-Рангарао Каніканті
Ханс-Юрген ХАМАНН
Петер КЛЯЙНЕБУДДЕ
Ріке Вітцлеб
Original Assignee
Баєр Інтеллекчуел Проперті Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41785839&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA105648(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Баєр Інтеллекчуел Проперті Гмбх filed Critical Баєр Інтеллекчуел Проперті Гмбх
Publication of UA105648C2 publication Critical patent/UA105648C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/606—Salicylic acid; Derivatives thereof having amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Винахід стосується екструдатів, що містять принаймні одну фармацевтично активну речовину в формі голок, причому співвідношення між розміром частинок голчатої фармацевтично активної речовини та діаметром штрангу становить щонайменше 1:25, а також застосування цих екструдатів для одержання лікарських засобів.
UAA201108386A 2008-12-05 2009-11-24 Екструдати з голчатими активними речовинами UA105648C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008060472 2008-12-05
PCT/EP2009/008341 WO2010063387A1 (de) 2008-12-05 2009-11-24 Extrudate mit nadelförmigen wirkstoffen

Publications (1)

Publication Number Publication Date
UA105648C2 true UA105648C2 (uk) 2014-06-10

Family

ID=41785839

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201108386A UA105648C2 (uk) 2008-12-05 2009-11-24 Екструдати з голчатими активними речовинами

Country Status (27)

Country Link
US (1) US20120034273A1 (uk)
EP (1) EP2373287B1 (uk)
JP (2) JP5860284B2 (uk)
KR (1) KR20110096145A (uk)
CN (1) CN102238940B (uk)
AR (1) AR075106A1 (uk)
AU (1) AU2009321822B2 (uk)
BR (1) BRPI0922302B8 (uk)
CA (1) CA2745456A1 (uk)
CL (1) CL2011001207A1 (uk)
CO (1) CO6440550A2 (uk)
CR (1) CR20110285A (uk)
DO (1) DOP2011000160A (uk)
EC (1) ECSP11011080A (uk)
ES (1) ES2685472T3 (uk)
IL (1) IL212846A0 (uk)
MX (1) MX2011005572A (uk)
NI (1) NI201100103A (uk)
NZ (1) NZ593217A (uk)
PE (1) PE20120182A1 (uk)
RU (1) RU2549450C2 (uk)
SV (1) SV2011003919A (uk)
TW (1) TWI522114B (uk)
UA (1) UA105648C2 (uk)
UY (1) UY32287A (uk)
WO (1) WO2010063387A1 (uk)
ZA (1) ZA201104145B (uk)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU231017B1 (hu) * 2012-05-08 2019-11-28 LAVET Gyógyszeripari Kft. Praziquantel tartalmú ízfedett formulációk
CN111803465B (zh) * 2013-03-15 2023-05-09 阿根塔创新有限公司 可咀嚼配制物
IN2013MU03583A (uk) * 2013-11-14 2015-07-31 Cipla Ltd
DE18837223T1 (de) 2017-07-26 2020-03-26 Tgx Soft Chew, Llc Stärkefreier weicher kausnack für veterinärmedizinische anwendungen
KR20230061465A (ko) 2020-09-04 2023-05-08 엘랑코 유에스 인코포레이티드 기호성 제형

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4402752B2 (ja) * 1997-05-19 2010-01-20 大日本住友製薬株式会社 免疫増強製剤
IT1298574B1 (it) * 1998-02-06 2000-01-12 Vectorpharma Int Composizioni farmaceutiche in forma di microparticelle a base polimerica ottenute mediante estrusione e sferonizzazione
DE19916383A1 (de) * 1999-03-31 2000-10-05 Schering Ag Pharmazeutische Zusammensetzung mit einem Extrusionsstoff
WO2003013525A1 (en) * 2001-08-06 2003-02-20 Euro-Celtique S.A. Opioid agonist formulations with releasable and sequestered antagonist
PL373148A1 (en) * 2002-06-27 2005-08-22 Cilag Ag Spherical pellet formulations
TWI347201B (en) * 2003-04-21 2011-08-21 Euro Celtique Sa Pharmaceutical products,uses thereof and methods for preparing the same
US20060165790A1 (en) * 2003-06-27 2006-07-27 Malcolm Walden Multiparticulates
EP1841414A1 (en) * 2003-12-31 2007-10-10 Alpharma, Inc. Rosiglitazone and metformin formulations
DE602004001969T2 (de) * 2004-02-20 2007-03-15 Mattern, Udo Orale pharmazeutische Zusammensetzung und Verfahren zu ihrer Herstellung
EP1690528A1 (de) * 2005-02-11 2006-08-16 Abbott GmbH & Co. KG Herstellung von Dosierungsformen mit einer festen Dispersion eines mikrokristallinen Wirkstoffs
WO2006090640A1 (ja) * 2005-02-23 2006-08-31 Taiyokagaku Co., Ltd. アミノ酸含有錠剤組成物および錠剤の製造方法
DE102005062270A1 (de) * 2005-12-24 2007-06-28 Bayer Technology Services Gmbh Geschmacksmaskierung von Pulvern
CA2665726C (en) * 2006-10-11 2016-04-19 Alpharma, Inc. Pharmaceutical compositions
DE102007026550A1 (de) * 2007-06-08 2008-12-11 Bayer Healthcare Ag Extrudate mit verbesserter Geschmacksmaskierung
CN101590020B (zh) * 2008-05-30 2012-02-08 上海新菲尔生物制药工程技术有限公司 一种对氨基水杨酸钠结肠定位给药系统

Also Published As

Publication number Publication date
CN102238940B (zh) 2014-07-30
JP2012510956A (ja) 2012-05-17
CA2745456A1 (en) 2010-06-10
CL2011001207A1 (es) 2011-10-28
BRPI0922302B1 (pt) 2020-09-15
US20120034273A1 (en) 2012-02-09
NZ593217A (en) 2013-05-31
ES2685472T3 (es) 2018-10-09
ZA201104145B (en) 2012-09-26
WO2010063387A1 (de) 2010-06-10
IL212846A0 (en) 2011-07-31
AR075106A1 (es) 2011-03-09
EP2373287A1 (de) 2011-10-12
JP2015134812A (ja) 2015-07-27
MX2011005572A (es) 2011-06-16
AU2009321822B2 (en) 2015-04-16
UY32287A (es) 2010-06-30
CN102238940A (zh) 2011-11-09
SV2011003919A (es) 2011-08-28
BRPI0922302A2 (pt) 2016-01-05
CO6440550A2 (es) 2012-05-15
RU2011127248A (ru) 2013-01-10
DOP2011000160A (es) 2011-06-30
KR20110096145A (ko) 2011-08-29
NI201100103A (es) 2012-04-16
ECSP11011080A (es) 2011-06-30
CR20110285A (es) 2011-09-27
PE20120182A1 (es) 2012-02-24
RU2549450C2 (ru) 2015-04-27
EP2373287B1 (de) 2018-05-30
BRPI0922302B8 (pt) 2021-05-25
HK1163547A1 (en) 2012-09-14
TW201031422A (en) 2010-09-01
JP5860284B2 (ja) 2016-02-16
TWI522114B (zh) 2016-02-21
AU2009321822A1 (en) 2011-06-30

Similar Documents

Publication Publication Date Title
MX2010008138A (es) Forma de dosis farmaceutica.
IL195294A (en) A process for the manufacture of high purity spinamide or relapinamide, their use in the preparation of medicaments and medicinal preparations containing them
GT201200250A (es) Ariltriazolonas ligadas a bisarilo y su uso
ZA201101097B (en) Pharmaceutical composition of n-[2,4-bis (1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and administration thereof
IL208832A (en) 3-Aminocarbazole Compound, Pharmaceutical Preparations Containing Them, Methods of Preparation and Use for Drug Preparation
CO6761350A2 (es) Derivados de 2,3-dihidroimidazo[1,2-c]quinazolina sustituidos con aminoalcoholes que son de utilidad para tratar trastornos hiperproliferativos y enfermedades asociadas a la angiogenesis
IL201479A (en) Use of tapentadol for the preparation of pain medication
IL204887A (en) Acetamide History, Pharmaceuticals Containing Them, Methods of Preparing and Using It in the Preparation of Diabetes Medications
IL216522A (en) Durable dosage form, packing containing it and method of preparation
WO2008052185A3 (en) Materials and methods for the treatment of celiac disease
CR20110042A (es) Forma cristalina de (2s)-(-)-n-(6-cloro-2,3-dihidro-benzo [1,4]dioxin-2-ilmetil)-sulfamida
IL198845A (en) An extended-release peptide preparation, a process for its preparation and use for drug preparation
ZA201006639B (en) Nanoparticle carriers for drug administration and process for producing the same
IL196825A0 (en) Methods, compositions and articles of manufacture for contributing to the treatment of cancers
IL184697A (en) Diclofenac Injection Composition, Process for its Preparation and Use for Medication and Pain Relief and / or Inflammation
NZ593217A (en) Extrudate having spicular active substances
WO2007089926A3 (en) Oxcarbazepine pharmaceutical formulation and its method of preparation, wherein oxcarbazepine has a broad and multi-modal particle size distribution
GEP20115158B (en) Use of ivabradine for obtaining medicaments intended for the treatment of endothelial dysfunction
HU0600668D0 (en) Active carrier, process for producing thereof and the use of thereof
IL204957A (en) Derivatives of 3 - (aminoalkoxyimino) - androstane and androsten
UA92604C2 (uk) Композиція стансопорфіну з фізіологічною осмотичною концентрацією та її застосування
PL1877035T3 (pl) Kompozycja farmaceutyczna i postać galenowa szybko rozpadająca się w jamie ustnej oraz sposób jej wytwarzania
ZA200900728B (en) Methods and pharmaceutical preparations for contributing to the treatment of chemotherapy-induced neuropathy
UA36724U (uk) Склад сухої мікстури від кашлю
UA33210U (uk) Спосіб лікування хворих на орнітозну інфекцію