UA42806C2 - Система для одночасного трансдермального введення кількох активних начал - Google Patents

Система для одночасного трансдермального введення кількох активних начал

Info

Publication number
UA42806C2
UA42806C2 UA97062931A UA97062931A UA42806C2 UA 42806 C2 UA42806 C2 UA 42806C2 UA 97062931 A UA97062931 A UA 97062931A UA 97062931 A UA97062931 A UA 97062931A UA 42806 C2 UA42806 C2 UA 42806C2
Authority
UA
Ukraine
Prior art keywords
active agents
amount
therapeutic dose
effective therapeutic
several active
Prior art date
Application number
UA97062931A
Other languages
English (en)
Russian (ru)
Inventor
Бруно Беван
Сесіль Айо
Сесиль Ае
Original Assignee
Лаборатуар Д'Іжьєн Е Де Дьєтетік
Лаборатуар Д'Ижьен э Де Дьететик
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лаборатуар Д'Іжьєн Е Де Дьєтетік, Лаборатуар Д'Ижьен э Де Дьететик filed Critical Лаборатуар Д'Іжьєн Е Де Дьєтетік
Publication of UA42806C2 publication Critical patent/UA42806C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Radiation-Therapy Devices (AREA)
  • Electrotherapy Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Система для черезшкірного введення включає перший засіб з сумішшю всіх активних агентів. Один перший активний агент міститься у кількості, що забезпечує ефективну терапевтичну дозу, що потрібно ввести. Другий активний агент міститься у кількості, яка менша потрібної для введення ефективної терапевтичної дози. Система також включає один або декілька додаткових засобів. Кожен з них містить один активний агент (В), що вибраний з присутніх у першому засобі. Всі вони знаходяться в кількості, яка менша тієї кількості, яка потрібна для одержання ефективної терапевтичної дози. Вказаний додатковий засіб чи засоби доставляють кожний з активних агентів, що містяться в системі у кількості, що необхідна для отримання ефективної терапевтичної дози.
UA97062931A 1994-12-21 1995-12-19 Система для одночасного трансдермального введення кількох активних начал UA42806C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9415416A FR2728463A1 (fr) 1994-12-21 1994-12-21 Systeme transdermique d'administration simultanee de plusieurs principes actifs
PCT/FR1995/001696 WO1996019203A1 (fr) 1994-12-21 1995-12-19 Systeme transdermique d'administration simultanee de plusieurs principes actifs

Publications (1)

Publication Number Publication Date
UA42806C2 true UA42806C2 (uk) 2001-11-15

Family

ID=9470067

Family Applications (1)

Application Number Title Priority Date Filing Date
UA97062931A UA42806C2 (uk) 1994-12-21 1995-12-19 Система для одночасного трансдермального введення кількох активних начал

Country Status (23)

Country Link
US (1) US5919477A (uk)
EP (1) EP0800386B1 (uk)
JP (1) JPH10510823A (uk)
KR (1) KR980700071A (uk)
CN (1) CN1072929C (uk)
AT (1) ATE173164T1 (uk)
AU (1) AU692042B2 (uk)
CA (1) CA2208374A1 (uk)
CZ (1) CZ183297A3 (uk)
DE (1) DE69506007T2 (uk)
DK (1) DK0800386T3 (uk)
ES (1) ES2125679T3 (uk)
FI (1) FI972542A7 (uk)
FR (1) FR2728463A1 (uk)
HU (1) HUT77384A (uk)
NO (1) NO972467L (uk)
NZ (1) NZ298826A (uk)
PL (1) PL182452B1 (uk)
RU (1) RU2157193C2 (uk)
SI (1) SI0800386T1 (uk)
SK (1) SK280631B6 (uk)
UA (1) UA42806C2 (uk)
WO (1) WO1996019203A1 (uk)

Families Citing this family (30)

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PT1019111E (pt) 1998-04-27 2002-10-31 Surmodics Inc Revestimento que liberta um agente bioactivo
US20020188037A1 (en) * 1999-04-15 2002-12-12 Chudzik Stephen J. Method and system for providing bioactive agent release coating
DE10025970C2 (de) * 2000-05-25 2002-04-25 Lohmann Therapie Syst Lts Estrogenhaltiges Pflaster mit einem Wirkstoffreservoir auf der Basis von Ethylcellulose und einem Ethylen-Vinylacetat-Vinylpyrrolidon-Copolymer und seine Verwendung
US6682757B1 (en) 2000-11-16 2004-01-27 Euro-Celtique, S.A. Titratable dosage transdermal delivery system
DE10141651B4 (de) * 2001-08-24 2007-02-15 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System (TTS) mit dem Wirkstoff Fentanyl und Verfahren zu seiner Herstellung
US7097850B2 (en) 2002-06-18 2006-08-29 Surmodics, Inc. Bioactive agent release coating and controlled humidity method
US7243788B2 (en) * 2003-10-22 2007-07-17 Kimberly-Clark Worldwide, Inc. Package for segregating and mixing substances
ES2626784T3 (es) * 2003-10-28 2017-07-26 Noven Pharmaceuticals, Inc. Dispositivo de administración transdérmica de fármacos
CN1964749A (zh) 2004-04-06 2007-05-16 苏莫迪克斯公司 用于生物活性剂的涂料组合物
WO2008006083A2 (en) 2006-07-07 2008-01-10 Surmodics, Inc. Beaded wound spacer device
US20090202609A1 (en) * 2008-01-06 2009-08-13 Keough Steven J Medical device with coating composition
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP2782584B1 (en) 2011-11-23 2021-06-09 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US9155671B2 (en) 2012-10-16 2015-10-13 Surmodics, Inc. Wound packing device and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
AR100562A1 (es) 2014-05-22 2016-10-12 Therapeuticsmd Inc Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666441A (en) * 1985-12-17 1987-05-19 Ciba-Geigy Corporation Multicompartmentalized transdermal patches
US5023084A (en) * 1986-12-29 1991-06-11 Rutgers, The State University Of New Jersey Transdermal estrogen/progestin dosage unit, system and process
US4911707A (en) * 1987-02-13 1990-03-27 Ciba-Geigy Corporation Monolithic user-activated transdermal therapeutic system
US5071656A (en) * 1987-03-05 1991-12-10 Alza Corporation Delayed onset transdermal delivery device
DE3714140A1 (de) * 1987-04-28 1988-11-10 Lohmann Therapie Syst Lts Wirkstoffhaltiges pflaster zur kontrollierten verabreichung von wirkstoffen an die haut, seine verwendung sowie verfahren zur gesteuerten verabreichung von wirkstoffen an die haut
US5538736A (en) * 1987-04-28 1996-07-23 Lts Lohmann Therapie-Systeme Gmbh Active substance-containing plaster for the controlled administration of active substances to the skin
DE3903794A1 (de) * 1989-02-09 1990-08-16 Lohmann Therapie Syst Lts Therapeutisches system zur transdermalen oder transmucosalen verabreichung von wirkstoffen und seine verwendung
US5788983A (en) * 1989-04-03 1998-08-04 Rutgers, The State University Of New Jersey Transdermal controlled delivery of pharmaceuticals at variable dosage rates and processes
US5350581A (en) * 1989-12-14 1994-09-27 Pharmetrix Corporation Method for manufacturing transdermal devices
US5064422A (en) * 1990-10-18 1991-11-12 Bertek, Inc. Twin patch applicator
DE4336557C2 (de) * 1993-05-06 1997-07-17 Lohmann Therapie Syst Lts Estradiolhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung

Also Published As

Publication number Publication date
FR2728463B1 (uk) 1997-02-21
AU692042B2 (en) 1998-05-28
NZ298826A (en) 1998-10-28
JPH10510823A (ja) 1998-10-20
HUT77384A (hu) 1998-04-28
ES2125679T3 (es) 1999-03-01
CN1072929C (zh) 2001-10-17
US5919477A (en) 1999-07-06
DE69506007D1 (de) 1998-12-17
FR2728463A1 (fr) 1996-06-28
CN1170359A (zh) 1998-01-14
SK79197A3 (en) 1997-12-10
SI0800386T1 (en) 1999-04-30
FI972542L (fi) 1997-06-16
HK1004375A1 (en) 1998-11-27
SK280631B6 (sk) 2000-05-16
PL182452B1 (pl) 2002-01-31
WO1996019203A1 (fr) 1996-06-27
DE69506007T2 (de) 1999-06-10
NO972467D0 (no) 1997-05-30
NO972467L (no) 1997-06-17
EP0800386B1 (fr) 1998-11-11
DK0800386T3 (da) 1999-07-26
RU2157193C2 (ru) 2000-10-10
EP0800386A1 (fr) 1997-10-15
CA2208374A1 (en) 1996-06-27
FI972542A0 (fi) 1997-06-16
PL320883A1 (en) 1997-11-10
AU4450596A (en) 1996-07-10
KR980700071A (ko) 1998-03-30
ATE173164T1 (de) 1998-11-15
CZ183297A3 (en) 1997-10-15
FI972542A7 (fi) 1997-06-16
MX9704527A (es) 1997-10-31

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