UA43332C2 - Сполука, що є похідним 2-амінобіцикло[3.1.0]гексан-2,6-дикарбонової кислоти, спосіб одержання цієї сполуки, фармацевтична композиція, що містить цю сполуку, проміжна сполука - Google Patents

Сполука, що є похідним 2-амінобіцикло[3.1.0]гексан-2,6-дикарбонової кислоти, спосіб одержання цієї сполуки, фармацевтична композиція, що містить цю сполуку, проміжна сполука

Info

Publication number
UA43332C2
UA43332C2 UA95083799A UA95083799A UA43332C2 UA 43332 C2 UA43332 C2 UA 43332C2 UA 95083799 A UA95083799 A UA 95083799A UA 95083799 A UA95083799 A UA 95083799A UA 43332 C2 UA43332 C2 UA 43332C2
Authority
UA
Ukraine
Prior art keywords
compound
aminobycycl
hexan
pharmaceutical
preparation
Prior art date
Application number
UA95083799A
Other languages
English (en)
Inventor
Девід Рід Хелтон
Джеймс Аллен Монн
Роджер Льюіс Роубі
Дарріл Дарвін ШЕПП
Джозеф Патрік Тіззано
Original Assignee
Елі Ліллі Енд Компані
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Елі Ліллі Енд Компані, Эли Лилли Энд Компани filed Critical Елі Ліллі Енд Компані
Publication of UA43332C2 publication Critical patent/UA43332C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/50—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms being part of the same condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/38—Unsaturated compounds containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Композиція інгредієнтів до горілки особливої містить спирт етиловий ректифікований, воду питну пом'якшену, ароматний спирт чебрецю, мед натуральний, додатково містить ароматний спирт меліси лікарської.
UA95083799A 1994-08-12 1995-08-14 Сполука, що є похідним 2-амінобіцикло[3.1.0]гексан-2,6-дикарбонової кислоти, спосіб одержання цієї сполуки, фармацевтична композиція, що містить цю сполуку, проміжна сполука UA43332C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28995794A 1994-08-12 1994-08-12
US33734994A 1994-11-10 1994-11-10
US08/496,643 US5750566A (en) 1994-08-12 1995-06-29 Synthetic excitatory amino acids

Publications (1)

Publication Number Publication Date
UA43332C2 true UA43332C2 (uk) 2001-12-17

Family

ID=26965934

Family Applications (1)

Application Number Title Priority Date Filing Date
UA95083799A UA43332C2 (uk) 1994-08-12 1995-08-14 Сполука, що є похідним 2-амінобіцикло[3.1.0]гексан-2,6-дикарбонової кислоти, спосіб одержання цієї сполуки, фармацевтична композиція, що містить цю сполуку, проміжна сполука

Country Status (5)

Country Link
US (2) US5750566A (uk)
KR (1) KR100375463B1 (uk)
BR (1) BR9503638A (uk)
CO (1) CO4410321A1 (uk)
UA (1) UA43332C2 (uk)

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PL182285B1 (pl) * 1994-08-12 2001-12-31 Lilly Co Eli Syntetyczne aminokwasy oraz ich estry i srodki farmaceutyczne je zawierajace PL PL PL PL PL PL PL
ATE206915T1 (de) * 1994-08-12 2001-11-15 Lilly Co Eli Behandlung von angstzuständen
ZA969485B (en) * 1995-11-16 1998-05-12 Lilly Co Eli Excitatory amino acid receptor antagonists.
US5824662A (en) * 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
CA2264043A1 (en) 1996-09-27 1998-04-02 Guilford Pharmaceuticals Inc. Naaladase compositions and methods for treating glutamate abnormality and effecting neuronal activity in animals
ZA983930B (en) * 1997-05-14 1999-11-08 Lilly Co Eli Excitatory amino acid receptor modulators.
US5891646A (en) * 1997-06-05 1999-04-06 Duke University Methods of assaying receptor activity and constructs useful in such methods
US6528271B1 (en) * 1997-06-05 2003-03-04 Duke University Inhibition of βarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesia
US7541151B2 (en) 1997-06-05 2009-06-02 Duke University Single-cell biosensor for the measurement of GPCR ligands in a test sample
US6124361A (en) * 1997-12-31 2000-09-26 Pfizer Inc Bicyclo[3.1.0]hexanes and related compounds
DE69906492T2 (de) 1998-01-28 2003-12-18 Taisho Pharmaceutical Co., Ltd. Fluorhaltige aminosäurederivate
US6521561B1 (en) 1998-05-01 2003-02-18 President And Fellows Of Harvard College Main-group metal based asymmetric catalysts and applications thereof
KR100469182B1 (ko) 1998-08-31 2005-02-02 다이쇼 세이야꾸 가부시끼가이샤 6-플루오로비시클로[3.1.0]헥산 유도체
PE20001236A1 (es) * 1998-11-13 2000-11-10 Lilly Co Eli Moduladores del receptor de aminoacidos excitadores
JP4505926B2 (ja) * 1999-03-25 2010-07-21 大正製薬株式会社 新規カルボン酸誘導体及びその製造方法
EP1164121B1 (en) * 1999-03-25 2008-10-29 Taisho Pharmaceutical Co., Ltd Novel carboxylic acid derivatives and process for producing the same
JP4192331B2 (ja) * 1999-04-16 2008-12-10 住友化学株式会社 光学活性２−オキソビシクロ［３．１．０］ヘキサン−６−カルボン酸誘導体の製造方法
US7038077B2 (en) * 2001-01-11 2006-05-02 Eli Lilly And Company Prodrugs of excitatory amino acids
HUP0400620A3 (en) * 2001-01-11 2012-09-28 Lilly Co Eli Prodrugs of excitatory amino acids and pharmaceutical compositions containing them and process for preparation the compounds
EP1310482A1 (en) * 2001-11-07 2003-05-14 Eli Lilly And Company Prodrugs of excitatory amino acids
US20040248963A1 (en) * 2001-11-23 2004-12-09 Bueno Melendo Ana Belen Prodrugs of excitatory amino acids
US7456221B2 (en) * 2001-12-21 2008-11-25 Eli Lilly And Company Prodrugs of excitatory amino acids
US20040116489A1 (en) * 2002-02-12 2004-06-17 Massey Steven Marc Synthetic excitatory amino acids
US20030182669A1 (en) * 2002-03-19 2003-09-25 Rockman Howard A. Phosphoinositide 3-kinase mediated inhibition of GPCRs
US20050192273A1 (en) * 2002-04-03 2005-09-01 Johnson Bryan G. Therapy for psychoses combining an atypical antipsychotic and an mglu2/3 receptor agonist
US7290215B2 (en) * 2002-06-03 2007-10-30 Microsoft Corporation Dynamic wizard interface system and method
PL1637517T3 (pl) * 2003-06-26 2011-04-29 Taisho Pharmaceutical Co Ltd Pochodne estrowe kwasu 2-aminobicyklo[3.1.0]heksano-2,6-dikarboksylowego
US20060217365A1 (en) * 2003-07-02 2006-09-28 Astrazeneca Ab Method of treating mood disorders
US20060217367A1 (en) * 2004-07-01 2006-09-28 Astrazeneca Ab Method of treating anxiety disorders
US20090093461A1 (en) * 2003-07-02 2009-04-09 Astrazeneca Ab Methods of Treating Anxiety and Mood Disorders
US20060252743A1 (en) * 2005-01-07 2006-11-09 Astrazeneca Ab Method of treating sleep disorders
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US20050107439A1 (en) * 2003-11-10 2005-05-19 Helton David R. Composition and method for treating emesis
EP2275095A3 (en) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
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EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
AU2006308889A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
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EP2382975A3 (en) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenesis by modulating angiotensin
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Also Published As

Publication number Publication date
BR9503638A (pt) 1996-05-28
KR960007545A (ko) 1996-03-22
US5750566A (en) 1998-05-12
KR100375463B1 (ko) 2003-04-23
CO4410321A1 (es) 1997-01-09
US5661184A (en) 1997-08-26

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