UA48150C2 - Похідні амінокислот або аміноспиртів, олігонуклеотид - Google Patents

Похідні амінокислот або аміноспиртів, олігонуклеотид Download PDF

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Publication number
UA48150C2
UA48150C2 UA97041995A UA97041995A UA48150C2 UA 48150 C2 UA48150 C2 UA 48150C2 UA 97041995 A UA97041995 A UA 97041995A UA 97041995 A UA97041995 A UA 97041995A UA 48150 C2 UA48150 C2 UA 48150C2
Authority
UA
Ukraine
Prior art keywords
oligomers
сно
bonds
denotes
evaporated
Prior art date
Application number
UA97041995A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Кандасамі Рамасамі
Гуанжі Ванг
Уілфрід Зайферт
Original Assignee
Ай-Сі-Ен Фармасьютикалз
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ай-Сі-Ен Фармасьютикалз filed Critical Ай-Сі-Ен Фармасьютикалз
Publication of UA48150C2 publication Critical patent/UA48150C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
UA97041995A 1994-11-02 1995-02-11 Похідні амінокислот або аміноспиртів, олігонуклеотид UA48150C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33389594A 1994-11-02 1994-11-02
PCT/US1995/014599 WO1996014330A1 (en) 1994-11-02 1995-11-02 Amino acid nucleic acids

Publications (1)

Publication Number Publication Date
UA48150C2 true UA48150C2 (uk) 2002-08-15

Family

ID=23304698

Family Applications (1)

Application Number Title Priority Date Filing Date
UA97041995A UA48150C2 (uk) 1994-11-02 1995-02-11 Похідні амінокислот або аміноспиртів, олігонуклеотид

Country Status (14)

Country Link
EP (1) EP0789707A4 (pl)
JP (1) JPH10508312A (pl)
KR (1) KR100393336B1 (pl)
CN (1) CN1171112A (pl)
AU (1) AU693622B2 (pl)
CA (1) CA2202274A1 (pl)
HU (1) HU218086B (pl)
MX (1) MX9703188A (pl)
PL (1) PL185852B1 (pl)
RU (1) RU2154638C2 (pl)
SI (1) SI9520112A (pl)
SK (1) SK2694U (pl)
UA (1) UA48150C2 (pl)
WO (1) WO1996014330A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840879A (en) * 1996-12-06 1998-11-24 Wang; Edge R. Reagents and solid supports for improved synthesis and labeling of polynucleotides
AU784370B2 (en) * 1999-12-22 2006-03-23 Metabasis Therapeutics, Inc. Novel bisamidate phosphonate prodrugs
AU2002256168B2 (en) * 2001-04-10 2007-09-20 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic and diagnostic uses of antibody specificity profiles
RU2606627C2 (ru) * 2007-11-15 2017-01-10 Серепта Терапьютикс,Инк. Способ синтеза морфолиновых олигомеров
US8865898B2 (en) 2010-11-30 2014-10-21 Japan Science And Technology Agency Nucleoside analog or salt thereof, oligonucleotide analog, gene expression inhibitor, and nucleic-acid probe for detecting gene
RU2460721C1 (ru) * 2011-02-25 2012-09-10 Учреждение Российской академии наук Институт химической биологии и фундаментальной медицины Сибирского отделения РАН (ИХБФМ СО РАН) Способ получения амидофосфитного мономера ахиральной ненуклеотидной вставки для модификации олигонуклеотидов
DE102014007158A1 (de) * 2014-05-16 2015-11-19 Ugichem Gmbh Neue Peptid-Nukleinsäuren-Monomere und -Oligomere
CN110678447B (zh) * 2017-06-16 2023-12-12 卫材R&D管理有限公司 经修饰的核酸单体化合物及寡核酸类似物
CN113956183B (zh) * 2021-10-28 2023-06-20 成都市科隆化学品有限公司 一种Boc-Ser(Bzl)-OH及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986005519A1 (en) * 1985-03-15 1986-09-25 James Summerton Polynucleotide assay reagent and method
DK51092D0 (da) * 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf

Also Published As

Publication number Publication date
PL320084A1 (en) 1997-09-15
KR100393336B1 (ko) 2003-12-24
CN1171112A (zh) 1998-01-21
KR970707144A (ko) 1997-12-01
MX9703188A (es) 1997-12-31
PL185852B1 (pl) 2003-08-29
SI9520112A (sl) 1998-08-31
AU693622B2 (en) 1998-07-02
RU2154638C2 (ru) 2000-08-20
EP0789707A4 (en) 1999-02-24
JPH10508312A (ja) 1998-08-18
EP0789707A1 (en) 1997-08-20
HUT77435A (hu) 1998-04-28
SK2694U (sk) 2000-11-07
AU4234196A (en) 1996-05-31
CA2202274A1 (en) 1996-05-17
WO1996014330A1 (en) 1996-05-17
HU218086B (hu) 2000-05-28

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