UA48936C2 - Спосіб одержання вірусу курячої анемії (cav) у дволанцюговій формі, рекомбінантна нуклеїнова кислота (варіанти), діагностичний набір (варіанти), вакцинний препарат (варіанти), культура клітин (варіанти), спосіб одержання діагностичного набору (варіанти) - Google Patents

Спосіб одержання вірусу курячої анемії (cav) у дволанцюговій формі, рекомбінантна нуклеїнова кислота (варіанти), діагностичний набір (варіанти), вакцинний препарат (варіанти), культура клітин (варіанти), спосіб одержання діагностичного набору (варіанти)

Info

Publication number
UA48936C2
UA48936C2 UA93004515A UA93004515A UA48936C2 UA 48936 C2 UA48936 C2 UA 48936C2 UA 93004515 A UA93004515 A UA 93004515A UA 93004515 A UA93004515 A UA 93004515A UA 48936 C2 UA48936 C2 UA 48936C2
Authority
UA
Ukraine
Prior art keywords
variants
production
cav
diagnostic set
recombinant
Prior art date
Application number
UA93004515A
Other languages
English (en)
Russian (ru)
Inventor
Матеус Хубертус Марія Нотеборн
Бур Гербен Фоппе де
Original Assignee
Лідд Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лідд Б.В. filed Critical Лідд Б.В.
Publication of UA48936C2 publication Critical patent/UA48936C2/uk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10041Use of virus, viral particle or viral elements as a vector
    • C12N2750/10043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/008Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/60Vector systems having a special element relevant for transcription from viruses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/816Viral vaccine for avian species, e.g. poultry or other birds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)

Abstract

Рекомбінантна генетична інформація (ДНК або РНК), що містить специфічну нуклеотидну послідовність вірусу курячої анемії (CAV) і використання її для діагностики, вакцинації або одержання протеїну. Рекомбінантний CAV-протеїн і використання його для діагностики, вакцинації або одержання CAV-специфічних антитіл. Використання отриманих у такий спосіб CAV-специфічних антитіл.
UA93004515A 1990-09-12 1991-09-11 Спосіб одержання вірусу курячої анемії (cav) у дволанцюговій формі, рекомбінантна нуклеїнова кислота (варіанти), діагностичний набір (варіанти), вакцинний препарат (варіанти), культура клітин (варіанти), спосіб одержання діагностичного набору (варіанти) UA48936C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL9002008A NL9002008A (nl) 1990-09-12 1990-09-12 Recombinant dna en rna en daarvan afgeleide produkten.
PCT/NL1991/000165 WO1992004446A1 (en) 1990-09-12 1991-09-11 Cloning of chicken anaemia dna

Publications (1)

Publication Number Publication Date
UA48936C2 true UA48936C2 (uk) 2002-09-16

Family

ID=19857669

Family Applications (1)

Application Number Title Priority Date Filing Date
UA93004515A UA48936C2 (uk) 1990-09-12 1991-09-11 Спосіб одержання вірусу курячої анемії (cav) у дволанцюговій формі, рекомбінантна нуклеїнова кислота (варіанти), діагностичний набір (варіанти), вакцинний препарат (варіанти), культура клітин (варіанти), спосіб одержання діагностичного набору (варіанти)

Country Status (21)

Country Link
US (6) US5491073A (uk)
EP (2) EP0548234B1 (uk)
JP (1) JP2846116B2 (uk)
AT (1) ATE188739T1 (uk)
AU (1) AU651999B2 (uk)
CA (1) CA2091181C (uk)
DE (1) DE69131903T2 (uk)
DK (1) DK0548234T3 (uk)
ES (1) ES2144399T3 (uk)
GR (1) GR3033173T3 (uk)
HR (1) HRP940668B1 (uk)
HU (1) HU220102B (uk)
IL (1) IL99435A (uk)
MX (1) MX9101042A (uk)
NL (1) NL9002008A (uk)
RU (1) RU2146292C1 (uk)
SI (1) SI9111508B (uk)
UA (1) UA48936C2 (uk)
WO (1) WO1992004446A1 (uk)
YU (1) YU49095B (uk)
ZA (1) ZA917065B (uk)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9301272A (nl) * 1993-07-20 1995-02-16 Aesculaap Bv Chicken Anemia Virus mutanten en vaccins en toepassingen gebaseerd op de virale eiwitten VP1, VP2 en VP3 of daarvoor coderende sequenties van dat virus.
US20080234466A1 (en) * 1990-09-12 2008-09-25 Noteborn Mathieu H M Delivery method for the tumor-specific apoptosis-inducing activity of apoptin
US20030138443A1 (en) * 1993-03-08 2003-07-24 Noteborn Mathews H.M. Cloning of chicken anemia virus DNA
US20020061296A1 (en) * 2000-09-08 2002-05-23 Noteborn Mathieu H.M. Delivery method for the tumor specific apoptosis inducing activity of apoptin
US5922600A (en) * 1990-09-12 1999-07-13 Leadd Bv Chicken anemia virus mutants and vaccines and uses based on the viral proteins VP1 VP2 and VP3 or sequences of that virus coding therefor
ZA918426B (en) * 1990-10-31 1992-12-30 Akzo Nv Chicken anemia virus vaccine and diagnostic
EP0878546A1 (en) * 1997-04-15 1998-11-18 Leadd B.V. A gene delivery vehicle expressing the apoptosis-inducing proteins VP2 and/or apoptin
US5789567A (en) * 1994-07-06 1998-08-04 Cornell Research Foundation, Inc. Chicken infectious anemia virus vaccine
GB9414888D0 (en) * 1994-07-23 1994-09-14 Univ Belfast Method and composition
CA2221570A1 (en) * 1995-06-07 1996-12-19 Aesculaap B.V. Neutralizing conformation epitopes of chicken anemia virus
CA2231729A1 (en) * 1995-11-14 1997-05-22 William L. Ragland Efficient method of detecting an infectious agent in blood
CZ299874B6 (cs) 1997-08-12 2008-12-17 Leadd B. V. Zpusob urcení transformacní schopnosti cinidel, zpusob urcení predispozice bunky, zpusob zjištení genové mutace, použití nukleové kyseliny kódující apoptin a diagnostická testovací souprava
EP1064024A4 (en) * 1998-03-13 2005-04-06 Univ Georgia Res Found VACCINES AGAINST CIRCOVIRUS INFECTIONS
NZ517740A (en) * 1999-09-02 2003-09-26 Leadd B Apoptin-associating protein and its use in the detection the presence of cancer cells
US7256274B2 (en) * 1999-12-10 2007-08-14 Leadd B.V. Apoptin-associating protein
US6593134B1 (en) 2000-03-10 2003-07-15 Cornell Research Foundation, Inc. Method of propagating chicken infectious anemia virus
EP1523921B1 (en) * 2000-07-10 2011-02-23 Uni-Charm Corporation Cleaning article
EP1199363A1 (en) * 2000-10-20 2002-04-24 Leadd B.V. Phosphorylation modifications of apoptin
AUPR567401A0 (en) * 2001-06-14 2001-07-12 University Of Melbourne, The Circovirus vaccines
CA2477811A1 (en) * 2001-09-05 2003-03-13 Biomune Chicken anemia virus vaccine from cell line
US7566548B2 (en) * 2004-08-13 2009-07-28 University Of Massachusetts Methods for identifying therapeutic agents and for treating disease
CN102636646A (zh) * 2012-05-15 2012-08-15 扬州大学 快速检测禽白血病抗原的试纸条及其制备方法
JP2022513459A (ja) * 2018-12-12 2022-02-08 フラッグシップ パイオニアリング イノベーションズ ブイ, インコーポレイテッド タンパク質代替治療モダリティを送達するためのアネロソーム

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2042888B (en) 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
JPS6034925B2 (ja) 1979-07-31 1985-08-12 帝人株式会社 持続性鼻腔用製剤およびその製造法
JPS6032714A (ja) 1983-08-01 1985-02-19 Teijin Ltd 鼻腔粘膜に適用するための安定化された粉末状薬学的組成物
DE3583799D1 (de) 1985-01-11 1991-09-19 Abbott Lab Ltd Feste zubereitung mit langsamer freisetzung.
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5059587A (en) 1987-08-03 1991-10-22 Toyo Jozo Company, Ltd. Physiologically active peptide composition for nasal administration
GB8723846D0 (en) 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
US5079005A (en) 1988-06-17 1992-01-07 Gupta Kashmiri L Time release protein
AU629248B2 (en) * 1988-09-13 1992-10-01 Merial Viral vaccines
GB2237510B (en) 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
US5271961A (en) 1989-11-06 1993-12-21 Alkermes Controlled Therapeutics, Inc. Method for producing protein microspheres
ZA918426B (en) * 1990-10-31 1992-12-30 Akzo Nv Chicken anemia virus vaccine and diagnostic

Also Published As

Publication number Publication date
CA2091181C (en) 2006-02-21
HRP940668B1 (en) 2000-10-31
SI9111508B (en) 2001-12-31
DK0548234T3 (da) 2000-06-19
US20020103336A1 (en) 2002-08-01
US6509446B2 (en) 2003-01-21
IL99435A (en) 2006-10-31
AU8658091A (en) 1992-03-30
HRP940668A2 (en) 1997-12-31
ATE188739T1 (de) 2000-01-15
US6238669B1 (en) 2001-05-29
YU150891A (sh) 1995-10-24
CA2091181A1 (en) 1992-03-13
NL9002008A (nl) 1992-04-01
RU2146292C1 (ru) 2000-03-10
US5958424A (en) 1999-09-28
HU9300716D0 (en) 1993-06-28
EP0548234B1 (en) 2000-01-12
GR3033173T3 (en) 2000-08-31
AU651999B2 (en) 1994-08-11
WO1992004446A1 (en) 1992-03-19
ES2144399T3 (es) 2000-06-16
HU220102B (hu) 2001-10-28
EP0905246A1 (en) 1999-03-31
DE69131903D1 (de) 2000-02-17
JP2846116B2 (ja) 1999-01-13
HUT65974A (en) 1994-08-29
YU49095B (sh) 2003-12-31
DE69131903T2 (de) 2000-07-20
MX9101042A (es) 1992-08-10
JPH06504195A (ja) 1994-05-19
US5932476A (en) 1999-08-03
IL99435A0 (en) 1992-08-18
US5491073A (en) 1996-02-13
SI9111508A (sl) 1998-10-31
ZA917065B (en) 1992-05-27
US6319693B1 (en) 2001-11-20
EP0548234A1 (en) 1993-06-30

Similar Documents

Publication Publication Date Title
UA48936C2 (uk) Спосіб одержання вірусу курячої анемії (cav) у дволанцюговій формі, рекомбінантна нуклеїнова кислота (варіанти), діагностичний набір (варіанти), вакцинний препарат (варіанти), культура клітин (варіанти), спосіб одержання діагностичного набору (варіанти)
RU93005170A (ru) Нуклеиновые кислоты, применение нуклеиновых кислот, диагностические наборы, вакцины, клетки, белок, применение белка, антитела, применение антител
FI912105A0 (fi) Neurotrofin-3, en ny neurotrofisk faktor haenfoerande sig till nerbtillvaextfaktorn och neurotrofisk faktor haerledd fraon hjaerna.
DE59611371D1 (de) Verfahren zur Herstellung von Erythropoietin frei von tierischen Proteinen
ATE172493T1 (de) Rekombinante dns-mittel und verfahren
ATE318896T1 (de) Rekombinante rna-replikase von hepatitis-c-virus
DE59702936D1 (de) Hantelförmige expressionskonstrukte für die gentherapie
HUP9900018A1 (hu) Cirkuláris DNS-molekula feltételes replikációs origóval, eljárás előállítására és génterápiában való felhasználására
DE59915205D1 (de) Strukturprotein von AAV, seine Herstellung und Verwendung
ES8706208A1 (es) Un metodo para preparar proteinas que son inmunologicamente reactivas con anticuerpos para virus asociados con linfadenopatia
ATE88500T1 (de) Dna-sequenzen, die fuer proteine mit der biologischen aktivitaet der husi-typi-inhibitoren codieren, gentechnologische verfahren zur herstellung dieser proteine und diese proteine enthaltende arzneimittel.
Borth et al. Different synthetic profiles and developmental fates of prespore versus prestalk proteins of Dictyostelium
DE3752131D1 (de) Impfstoffe und diagnosetest für haemophilus influenzae
KR890008317A (ko) 유전학적 조작에 의한 응고억제성 단백질 pp4의 제조방법
BR9713450A (pt) Quimiocinas de mamìfero
EP0316170A3 (en) Method for the identification of antigens expressed in vivo, diagnostic assays therefor and vaccines containing them
FR2600079B1 (fr) Vecteur viral et adn recombinant codant pour la proteine f du virus agent causal du s.i.d.a., culture cellulaire infectee par ce vecteur, procede de preparation de la proteine, proteine obtenue, vaccin et anticorps obtenus
ATE331794T1 (de) Humane prostacyclinsynthase
Howard et al. The surgical significance of viruses
KR950000879A (ko) 신규한 인간 면역결핍 바이러스-2(hiv-2)
Miller Jr Viral Immunodiagnosis
Check California team manipulates bacteria to mass-produce natural opiate
Alberts DNA-unwinding proteins and their role in the replication of DNA
Cox et al. Template properties of bacteriophage T4 vegetative DNA. I. Isolation and characterization of two template fractions from gently lysed T4-infected bacteria
Hollingshead THE MUCOSAL IMMUNE RESPONSE OF SWINE AND ITS RELATIONSHIP TO INFECTION WITH AN ENTERIC CORONAVIRUS (TRANSMISSIBLE GASTROENTERITIS)