UA77999C2 - Thymosin-alpha 1 for treatment of malignant glioblastoma - Google Patents

Thymosin-alpha 1 for treatment of malignant glioblastoma Download PDF

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Publication number
UA77999C2
UA77999C2 UA20040705523A UA20040705523A UA77999C2 UA 77999 C2 UA77999 C2 UA 77999C2 UA 20040705523 A UA20040705523 A UA 20040705523A UA 20040705523 A UA20040705523 A UA 20040705523A UA 77999 C2 UA77999 C2 UA 77999C2
Authority
UA
Ukraine
Prior art keywords
cells
thymalfazin
tumor
treated
glioblastoma
Prior art date
Application number
UA20040705523A
Other languages
English (en)
Ukrainian (uk)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of UA77999C2 publication Critical patent/UA77999C2/uk

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2292Thymosin; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prostheses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
UA20040705523A 2001-12-10 2002-10-12 Thymosin-alpha 1 for treatment of malignant glioblastoma UA77999C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33714901P 2001-12-10 2001-12-10
PCT/US2002/039329 WO2003049697A2 (en) 2001-12-10 2002-12-10 Treatment of glioblastoma with thymosin-alpha 1

Publications (1)

Publication Number Publication Date
UA77999C2 true UA77999C2 (en) 2007-02-15

Family

ID=23319320

Family Applications (1)

Application Number Title Priority Date Filing Date
UA20040705523A UA77999C2 (en) 2001-12-10 2002-10-12 Thymosin-alpha 1 for treatment of malignant glioblastoma

Country Status (22)

Country Link
US (1) US20060166870A1 (de)
EP (1) EP1461063B1 (de)
JP (1) JP2005516910A (de)
KR (2) KR20040091611A (de)
CN (1) CN1615147A (de)
AT (1) ATE356628T1 (de)
AU (1) AU2002357115B2 (de)
BR (1) BR0214848A (de)
CA (1) CA2469595A1 (de)
DE (1) DE60218896T2 (de)
DK (1) DK1461063T3 (de)
EA (1) EA005822B1 (de)
ES (1) ES2283653T3 (de)
IL (1) IL162434A0 (de)
MX (1) MXPA04005585A (de)
NO (1) NO20042927L (de)
NZ (1) NZ533942A (de)
PL (1) PL370829A1 (de)
PT (1) PT1461063E (de)
SI (1) SI1461063T1 (de)
UA (1) UA77999C2 (de)
WO (1) WO2003049697A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2288118B1 (es) 2006-05-10 2008-11-01 Bcn Peptides, S.A. Procedimiento para sintetizar timosinas.
CN108226016A (zh) * 2018-01-12 2018-06-29 浙江普罗亭健康科技有限公司 肿瘤免疫细胞亚群精准分型的质谱流式检测试剂盒
CN112147326B (zh) * 2020-09-04 2022-04-08 北京大学 一种肿瘤免疫细胞亚群分型精准检测试剂盒

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4079127A (en) * 1976-10-28 1978-03-14 Board Of Regents Of The University Of Texas Thymosin alpha 1
US4116951A (en) * 1977-04-22 1978-09-26 Hoffmann-La Roche Inc. [Asn2 ]-thymosin α1 and analogs thereof
US4148786A (en) * 1978-06-26 1979-04-10 American Home Products Corporation Analgesic polypeptide
DE2919592A1 (de) * 1979-05-15 1981-01-15 Max Planck Gesellschaft Verfahren zur herstellung von thymosin- alpha 1 und derivaten davon
IT1238231B (it) * 1989-12-18 1993-07-12 Consiglio Nazionale Ricerche Impiego di immunomodulanti come agenti sinergici di chemioterapici nella terapia dei tumori
FR2793684B1 (fr) * 1999-05-17 2001-08-10 Ethypharm Lab Prod Ethiques Utilisation de microspheres biodegradables liberant un agent anticancereux pour le traitement du glioblastome, procede de preparation de ces microspheres et suspension les contenant
US6462017B1 (en) * 2000-05-01 2002-10-08 Sciclone Pharmaceuticals, Inc. Method of reducing side effects of chemotherapy in cancer patients

Also Published As

Publication number Publication date
EP1461063B1 (de) 2007-03-14
DE60218896T2 (de) 2007-09-20
WO2003049697A2 (en) 2003-06-19
NO20042927L (no) 2004-09-09
ATE356628T1 (de) 2007-04-15
PT1461063E (pt) 2007-06-18
EA200400755A1 (ru) 2004-12-30
WO2003049697A3 (en) 2004-01-15
NZ533942A (en) 2007-01-26
ES2283653T3 (es) 2007-11-01
CN1615147A (zh) 2005-05-11
AU2002357115A1 (en) 2003-06-23
BR0214848A (pt) 2004-11-09
JP2005516910A (ja) 2005-06-09
EP1461063A2 (de) 2004-09-29
MXPA04005585A (es) 2005-03-23
CA2469595A1 (en) 2003-06-19
EP1461063A4 (de) 2005-08-31
DK1461063T3 (da) 2007-05-21
IL162434A0 (en) 2005-11-20
PL370829A1 (en) 2005-05-30
EA005822B1 (ru) 2005-06-30
KR20040091611A (ko) 2004-10-28
AU2002357115B2 (en) 2007-12-13
DE60218896D1 (de) 2007-04-26
KR20100029844A (ko) 2010-03-17
US20060166870A1 (en) 2006-07-27
SI1461063T1 (sl) 2007-08-31

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