UA79737C2 - Method for the production of imidazo-(1,2-c)(2,3)-benzodiazepines and intermediates in the production thereof - Google Patents

Method for the production of imidazo-(1,2-c)(2,3)-benzodiazepines and intermediates in the production thereof Download PDF

Info

Publication number: UA79737C2
Authority: UA; Ukraine
Prior art keywords: group; halogen; general formula; hydrogen; optionally substituted
Prior art date: 2000-08-10

Application number

UA2003032066A

Other languages

English (en)

Ukrainian (uk)

Inventor

Eric Winter

Matthias Schneider

Ulf Tilstam

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-10

Filing date

2001-07-26

Publication date

2007-07-25

2001-07-26 Application filed by Schering Ag filed Critical Schering Ag

2007-07-25 Publication of UA79737C2 publication Critical patent/UA79737C2/uk

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

UA2003032066A 2000-08-10 2001-07-26 Method for the production of imidazo-(1,2-c)(2,3)-benzodiazepines and intermediates in the production thereof UA79737C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10041671A DE10041671C1 (de)	2000-08-10	2000-08-10	Verfahren zur Herstellung von Imidazo[1,2-c][2,3]benzodiazepinen sowie Phenylessigsäureester und Oxazol-Derivate als Zwischenprodukte bei deren Herstellung
PCT/EP2001/008661 WO2002012247A1 (fr)	2000-08-10	2001-07-26	Procede de fabrication d'imidazo(1,2-c)(2,3)benzodiazepines et produits intermediaires pour cette fabrication

Publications (1)

Publication Number	Publication Date
UA79737C2 true UA79737C2 (en)	2007-07-25

Family

ID=7653689

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA2003032066A UA79737C2 (en)	2000-08-10	2001-07-26	Method for the production of imidazo-(1,2-c)(2,3)-benzodiazepines and intermediates in the production thereof

Country Status (30)

Country	Link
US (1)	US6784292B2 (fr)
EP (1)	EP1307460B1 (fr)
JP (1)	JP2004505981A (fr)
KR (1)	KR20030021263A (fr)
CN (1)	CN1205213C (fr)
AT (1)	ATE260921T1 (fr)
AU (2)	AU2001278512B2 (fr)
BG (1)	BG107519A (fr)
BR (1)	BR0112810A (fr)
CA (1)	CA2417804A1 (fr)
CZ (1)	CZ2003676A3 (fr)
DE (2)	DE10041671C1 (fr)
DK (1)	DK1307460T3 (fr)
EA (1)	EA005570B1 (fr)
EE (1)	EE200300058A (fr)
ES (1)	ES2217173T3 (fr)
HR (1)	HRP20030174A2 (fr)
HU (1)	HUP0301500A3 (fr)
IL (1)	IL154165A0 (fr)
MX (1)	MXPA02012913A (fr)
NO (1)	NO20030605L (fr)
NZ (1)	NZ523479A (fr)
PL (1)	PL359586A1 (fr)
PT (1)	PT1307460E (fr)
SK (1)	SK2892003A3 (fr)
TR (1)	TR200401281T4 (fr)
UA (1)	UA79737C2 (fr)
WO (1)	WO2002012247A1 (fr)
YU (1)	YU8903A (fr)
ZA (1)	ZA200301862B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPWO2007119361A1 (ja) *	2006-03-17	2009-08-27	三菱瓦斯化学株式会社	キナゾリン−４−オン誘導体の製造方法
KR200453637Y1 (ko) *	2009-06-23	2011-05-19	(주)대양스톤	씽크대용 볼 고정장치
CN104557533A (zh) *	2015-01-22	2015-04-29	中国石油大学(华东)	一种磷钨酸催化合成乙偶姻短链脂肪酸酯的方法
CN104498543B (zh) *	2015-01-22	2017-10-31	中国石油大学(华东)	一种脂肪酶催化合成乙偶姻脂肪酸酯的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19604919A1 (de)	1996-02-01	1997-08-07	Schering Ag	Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
HUP9701325A1 (hu) *	1997-07-31	2000-08-28	Gyógyszerkutató Intézet Kft.	Új 2,3-benzodiazepin-származékok

2000
- 2000-08-10 DE DE10041671A patent/DE10041671C1/de not_active Expired - Lifetime
2001
- 2001-07-26 AU AU2001278512A patent/AU2001278512B2/en not_active Ceased
- 2001-07-26 MX MXPA02012913A patent/MXPA02012913A/es active IP Right Grant
- 2001-07-26 KR KR10-2003-7001796A patent/KR20030021263A/ko not_active Ceased
- 2001-07-26 ES ES01956566T patent/ES2217173T3/es not_active Expired - Lifetime
- 2001-07-26 WO PCT/EP2001/008661 patent/WO2002012247A1/fr not_active Ceased
- 2001-07-26 CA CA002417804A patent/CA2417804A1/fr not_active Abandoned
- 2001-07-26 AU AU7851201A patent/AU7851201A/xx active Pending
- 2001-07-26 EP EP01956566A patent/EP1307460B1/fr not_active Expired - Lifetime
- 2001-07-26 PT PT01956566T patent/PT1307460E/pt unknown
- 2001-07-26 IL IL15416501A patent/IL154165A0/xx unknown
- 2001-07-26 CN CNB018139876A patent/CN1205213C/zh not_active Expired - Fee Related
- 2001-07-26 CZ CZ2003676A patent/CZ2003676A3/cs unknown
- 2001-07-26 DE DE50101634T patent/DE50101634D1/de not_active Expired - Fee Related
- 2001-07-26 HR HR20030174A patent/HRP20030174A2/hr not_active Application Discontinuation
- 2001-07-26 BR BR0112810-8A patent/BR0112810A/pt not_active IP Right Cessation
- 2001-07-26 YU YU8903A patent/YU8903A/sh unknown
- 2001-07-26 HU HU0301500A patent/HUP0301500A3/hu unknown
- 2001-07-26 US US10/344,156 patent/US6784292B2/en not_active Expired - Fee Related
- 2001-07-26 AT AT01956566T patent/ATE260921T1/de not_active IP Right Cessation
- 2001-07-26 PL PL01359586A patent/PL359586A1/xx not_active Application Discontinuation
- 2001-07-26 SK SK289-2003A patent/SK2892003A3/sk unknown
- 2001-07-26 EE EEP200300058A patent/EE200300058A/xx unknown
- 2001-07-26 JP JP2002518222A patent/JP2004505981A/ja active Pending
- 2001-07-26 DK DK01956566T patent/DK1307460T3/da active
- 2001-07-26 UA UA2003032066A patent/UA79737C2/uk unknown
- 2001-07-26 NZ NZ523479A patent/NZ523479A/en unknown
- 2001-07-26 TR TR2004/01281T patent/TR200401281T4/xx unknown
- 2001-07-26 EA EA200300220A patent/EA005570B1/ru not_active IP Right Cessation
2003
- 2003-02-04 BG BG107519A patent/BG107519A/bg unknown
- 2003-02-07 NO NO20030605A patent/NO20030605L/no not_active Application Discontinuation
- 2003-03-06 ZA ZA200301862A patent/ZA200301862B/en unknown

Also Published As

Publication number	Publication date
US20040019041A1 (en)	2004-01-29
EE200300058A (et)	2004-12-15
DK1307460T3 (da)	2004-06-28
CN1205213C (zh)	2005-06-08
CN1446220A (zh)	2003-10-01
BG107519A (bg)	2003-06-30
HUP0301500A3 (en)	2007-07-30
EA200300220A1 (ru)	2003-08-28
HUP0301500A2 (hu)	2003-08-28
DE50101634D1 (de)	2004-04-08
AU7851201A (en)	2002-02-18
DE10041671C1 (de)	2002-06-13
EP1307460A1 (fr)	2003-05-07
NO20030605D0 (no)	2003-02-07
PL359586A1 (en)	2004-08-23
ZA200301862B (en)	2004-03-08
NZ523479A (en)	2006-10-27
EA005570B1 (ru)	2005-04-28
WO2002012247A1 (fr)	2002-02-14
US6784292B2 (en)	2004-08-31
ES2217173T3 (es)	2004-11-01
BR0112810A (pt)	2003-07-01
NO20030605L (no)	2003-02-07
ATE260921T1 (de)	2004-03-15
CA2417804A1 (fr)	2003-01-30
JP2004505981A (ja)	2004-02-26
PT1307460E (pt)	2004-07-30
AU2001278512B2 (en)	2006-09-07
SK2892003A3 (en)	2003-09-11
TR200401281T4 (tr)	2004-07-21
HRP20030174A2 (en)	2004-06-30
EP1307460B1 (fr)	2004-03-03
CZ2003676A3 (cs)	2003-06-18
MXPA02012913A (es)	2003-10-14
IL154165A0 (en)	2003-07-31
YU8903A (sh)	2006-01-16
KR20030021263A (ko)	2003-03-12

Publication	Publication Date	Title
JP3051076B2 (ja)	2000-06-12	複素環式−環式アミン誘導体合成のための中間体
CA2467261C (fr)	2010-10-12	Nouveaux derives de benzophenone ou sels de ceux-ci
JPH0751562B2 (ja)	1995-06-05	４−置換１，４−ジヒドロピリジン類の新規製法
JP2013533267A (ja)	2013-08-22	５位で置換されたべンゾフラン誘導体の調製方法
Han et al.	2017	Diastereoselective [3+ 2] cycloaddition of 3-ylideneoxindoles with in situ generated CF2HCHN2: syntheses of CF2H-containing spirooxindoles
EP3737685B1 (fr)	2023-03-29	Procédé de préparation de crisaborole et de ses intermédiaires
CN112174823A (zh)	2021-01-05	一种合成2,2-二甲基-3-氧杂环丁酮的中间体及其制备方法和应用
CN107513050A (zh)	2017-12-26	一种烯酸溴内酯化的制备方法
US6784292B2 (en)	2004-08-31	Method for the production of imidazo-(1,2-C)(2,3)-benzodiazepines and intermediates in the production thereof
IE59655B1 (en)	1994-03-09	Thianaphthene derivatives, their production and use
CN108484500B (zh)	2021-05-04	一种1-三氟乙基异喹啉的制备方法
TW202423907A (zh)	2024-06-16	用於製備經取代之烯烴的脫去反應
JPS6135194B2 (fr)	1986-08-12
Nadal et al.	2009	Synthesis of vulpinic acids from dimethyl tartrate
Wang et al.	2019	A highly selective H/D exchange reaction of 1, 4-dihydropyridines
Pavlik et al.	2005	Synthesis of 3‐phenyl‐5‐(trifluoromethyl) isoxazole and 5‐phenyl‐3‐(trifluoromethyl) isoxazole
JPWO2002081420A1 (ja)	2004-07-29	シクロオクタノン誘導体およびシクロデカノン誘導体、およびその用途
JP2007126358A (ja)	2007-05-24	フェニルアラニン誘導体
Masui et al.	2017	One-Pot, Diversity-Oriented Synthesis of Aryl-Substituted Benzoxacycles Including Benzofuran, Coumarin, and Benzoxazepine
JPH05213811A (ja)	1993-08-24	サイシンｎ誘導体
YAMANAKA et al.	1981	Hydration and Hydrogenation of Acetylenic Side-Chains at the 4-or 5-Position of Isoxazoles
CN107353266A (zh)	2017-11-17	一种烯酸溴内酯化的制备方法
JPS63264448A (ja)	1988-11-01	新規β−ケトニトリル
JPH10338677A (ja)	1998-12-22	オキサゾリンを用いるクロロケトンの製造方法
JP2023538694A (ja)	2023-09-08	置換アクリレート化合物の製造