UA90461C2 - Pyrazole derivatives as protein kinase modulators - Google Patents

Pyrazole derivatives as protein kinase modulators

Info

Publication number: UA90461C2
Authority: UA; Ukraine
Prior art keywords: group; carbon atoms; compounds; protein kinase; atoms
Prior art date: 2003-12-23

Application number

UAA200608166A

Other languages

English (en)

Russian (ru)

Inventor

Валерио Бердини

Гордон Саксти

Маринус Леендерт Вердонк

Стивен Джон Вудхед

Поль Грехем Уайатт

Роберт Георг Бойл

Ханна Фиона Соре

Девид Уинтер Уокер

Иан Коллинз

Роберт Даунем

Робин Артур Эллис Карр

Original Assignee

Астекс Терапьютикс Лимитед

Кенсер Рисьёрч Текнолоджи Лимитед

Дзе Инститьют Оф Кенсер Рисьёрч: Ройял Кенсер Хоспитал

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-23

Filing date

2004-12-23

Publication date

2010-05-11

2004-12-23 Application filed by Астекс Терапьютикс Лимитед, Кенсер Рисьёрч Текнолоджи Лимитед, Дзе Инститьют Оф Кенсер Рисьёрч: Ройял Кенсер Хоспитал filed Critical Астекс Терапьютикс Лимитед

2010-05-11 Publication of UA90461C2 publication Critical patent/UA90461C2/ru

Links

102000001253 Protein Kinase Human genes 0.000 title 1
108060006633 protein kinase Proteins 0.000 title 1
150000003217 pyrazoles Chemical class 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 5
150000001875 compounds Chemical class 0.000 abstract 3
125000005647 linker group Chemical group 0.000 abstract 3
125000004429 atom Chemical group 0.000 abstract 2
229910052799 carbon Inorganic materials 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
125000004043 oxo group Chemical group O=* 0.000 abstract 2
MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
108091008611 Protein Kinase B Proteins 0.000 abstract 1
102000005765 Proto-Oncogene Proteins c-akt Human genes 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000002527 bicyclic carbocyclic group Chemical group 0.000 abstract 1
229910052731 fluorine Inorganic materials 0.000 abstract 1
239000011737 fluorine Substances 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
125000002950 monocyclic group Chemical group 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

UAA200608166A 2003-12-23 2004-12-23 Pyrazole derivatives as protein kinase modulators UA90461C2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB0329617A GB0329617D0 (en)	2003-12-23	2003-12-23	Pharmaceutical compounds

Publications (1)

Publication Number	Publication Date
UA90461C2 true UA90461C2 (en)	2010-05-11

Family

ID=30776233

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UAA200608166A UA90461C2 (en)	2003-12-23	2004-12-23	Pyrazole derivatives as protein kinase modulators

Country Status (11)

Country	Link
CN (1)	CN1922148B (fr)
AT (1)	ATE483689T1 (fr)
DE (1)	DE602004029501D1 (fr)
DK (1)	DK1706385T3 (fr)
GB (1)	GB0329617D0 (fr)
ME (1)	ME01934B (fr)
PT (1)	PT1706385E (fr)
RS (1)	RS51546B (fr)
SI (1)	SI1706385T1 (fr)
UA (1)	UA90461C2 (fr)
ZA (1)	ZA200605127B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0704932D0 (en) *	2007-03-14	2007-04-25	Astex Therapeutics Ltd	Pharmaceutical compounds
CN108339121A (zh) *	2017-01-25	2018-07-31	苏州大学	蛋白激酶a抑制剂在制备治疗血小板数量增多相关疾病药物中的用途
CN111056990B (zh) *	2019-12-16	2022-06-17	爱斯特（成都）生物制药股份有限公司	一种合成1-叔丁氧羰基-4-(4-羧基苯基)哌啶的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9804734D0 (en) *	1998-03-05	1998-04-29	Pfizer Ltd	Compounds
AU6388900A (en) *	1999-07-30	2001-02-19	Abbott Gmbh & Co. Kg	2-pyrazolin-5-ones

2003
- 2003-12-23 GB GB0329617A patent/GB0329617D0/en not_active Ceased
2004
- 2004-12-23 RS RSP-2010/0532A patent/RS51546B/sr unknown
- 2004-12-23 SI SI200431571T patent/SI1706385T1/sl unknown
- 2004-12-23 UA UAA200608166A patent/UA90461C2/ru unknown
- 2004-12-23 DK DK04806258.2T patent/DK1706385T3/da active
- 2004-12-23 AT AT04806258T patent/ATE483689T1/de active
- 2004-12-23 ME MEP-2010-532A patent/ME01934B/fr unknown
- 2004-12-23 PT PT04806258T patent/PT1706385E/pt unknown
- 2004-12-23 DE DE602004029501T patent/DE602004029501D1/de not_active Expired - Lifetime
- 2004-12-23 CN CN2004800420375A patent/CN1922148B/zh not_active Expired - Fee Related
2006
- 2006-06-21 ZA ZA200605127A patent/ZA200605127B/xx unknown

Also Published As

Publication number	Publication date
CN1922148A (zh)	2007-02-28
DK1706385T3 (da)	2011-01-10
DE602004029501D1 (de)	2010-11-18
PT1706385E (pt)	2010-12-22
SI1706385T1 (sl)	2011-01-31
GB0329617D0 (en)	2004-01-28
ATE483689T1 (de)	2010-10-15
ZA200605127B (en)	2010-07-28
RS51546B (sr)	2011-06-30
CN1922148B (zh)	2012-03-21
ME01934B (fr)	2011-06-30

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