UA98772C2 - Производные циклопропиламина как модуляторы н3-гистаминового рецептора - Google Patents
Производные циклопропиламина как модуляторы н3-гистаминового рецептораInfo
- Publication number
- UA98772C2 UA98772C2 UAA200900472A UAA200900472A UA98772C2 UA 98772 C2 UA98772 C2 UA 98772C2 UA A200900472 A UAA200900472 A UA A200900472A UA A200900472 A UAA200900472 A UA A200900472A UA 98772 C2 UA98772 C2 UA 98772C2
- Authority
- UA
- Ukraine
- Prior art keywords
- histamin
- receptor modulators
- amine derivatives
- cyclopropyl amine
- compounds
- Prior art date
Links
- HTJDQJBWANPRPF-UHFFFAOYSA-N Cyclopropylamine Chemical class NC1CC1 HTJDQJBWANPRPF-UHFFFAOYSA-N 0.000 title 1
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003446 ligand Substances 0.000 abstract 2
- 230000001668 ameliorated effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Anesthesiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Соединения формулы (I)(I),полезны при лечении состояний или нарушений, которые предотвращают или которые облегчают с помощью лигандов Н-гистаминовых рецепторов.Также раскрыты фармацевтические композиции, которые содержат лиганды Н-гистаминовых рецепторов, применение таких соединений и композиций и способ получения соединений, которые входят в область, которая определяется формулой (I).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81593406P | 2006-06-23 | 2006-06-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA98772C2 true UA98772C2 (ru) | 2012-06-25 |
Family
ID=38670977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200900472A UA98772C2 (ru) | 2006-06-23 | 2007-06-22 | Производные циклопропиламина как модуляторы н3-гистаминового рецептора |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US8829041B2 (ru) |
| EP (1) | EP2049472B1 (ru) |
| JP (1) | JP5203360B2 (ru) |
| KR (1) | KR20090024811A (ru) |
| CN (2) | CN101472887A (ru) |
| AU (1) | AU2007260836B2 (ru) |
| BR (1) | BRPI0712823A2 (ru) |
| CA (1) | CA2655604C (ru) |
| CR (1) | CR10540A (ru) |
| DO (1) | DOP2011000283A (ru) |
| EC (1) | ECSP099046A (ru) |
| ES (1) | ES2533009T3 (ru) |
| IL (1) | IL196094A0 (ru) |
| MX (1) | MX2008016343A (ru) |
| NO (1) | NO20090282L (ru) |
| NZ (2) | NZ597498A (ru) |
| RU (1) | RU2449989C2 (ru) |
| SG (1) | SG173312A1 (ru) |
| TW (1) | TW200808773A (ru) |
| UA (1) | UA98772C2 (ru) |
| UY (1) | UY31527A1 (ru) |
| WO (1) | WO2007150010A2 (ru) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006132914A2 (en) * | 2005-06-03 | 2006-12-14 | Abbott Laboratories | Cyclobutyl amine derivatives |
| CA2655604C (en) | 2006-06-23 | 2016-08-09 | Abbott Laboratories | Cyclopropyl amine derivatives |
| US9108948B2 (en) * | 2006-06-23 | 2015-08-18 | Abbvie Inc. | Cyclopropyl amine derivatives |
| CN101835750B (zh) | 2007-08-22 | 2013-07-17 | 阿斯利康(瑞典)有限公司 | 环丙基酰胺衍生物 |
| AU2013216616B2 (en) * | 2007-12-14 | 2016-04-21 | Abbvie Bahamas Ltd. | Cyclopropyl amine derivatives |
| TW201039825A (en) * | 2009-02-20 | 2010-11-16 | Astrazeneca Ab | Cyclopropyl amide derivatives 983 |
| US9186353B2 (en) * | 2009-04-27 | 2015-11-17 | Abbvie Inc. | Treatment of osteoarthritis pain |
| US20110201623A1 (en) | 2010-02-18 | 2011-08-18 | Uczynski Michael A | Crystalline Form Of A Cyclopropyl Benzamide Derivative |
| JP5746718B2 (ja) * | 2010-02-18 | 2015-07-08 | アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag | シクロプロピルアミド誘導体からなる固体形態 |
| WO2012037258A1 (en) | 2010-09-16 | 2012-03-22 | Abbott Laboratories | Processes for preparing 1,2-substituted cyclopropyl derivatives |
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| GB8615313D0 (en) | 1986-06-23 | 1986-07-30 | Ici Plc | Chemical process |
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| UA71945C2 (en) | 1999-01-27 | 2005-01-17 | Pfizer Prod Inc | Substituted bicyclic derivatives being used as anticancer agents |
| WO2000063208A1 (en) | 1999-04-16 | 2000-10-26 | Novo Nordisk A/S | Substituted imidazoles, their preparation and use |
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| SG173312A1 (en) | 2011-08-29 |
| ES2533009T3 (es) | 2015-04-06 |
| KR20090024811A (ko) | 2009-03-09 |
| US20080021081A1 (en) | 2008-01-24 |
| AU2007260836A1 (en) | 2007-12-27 |
| AU2007260836B2 (en) | 2012-11-15 |
| UY31527A1 (es) | 2009-08-03 |
| DOP2011000283A (es) | 2011-10-31 |
| RU2449989C2 (ru) | 2012-05-10 |
| CA2655604C (en) | 2016-08-09 |
| CN103382174A (zh) | 2013-11-06 |
| JP2009541350A (ja) | 2009-11-26 |
| EP2049472B1 (en) | 2015-01-21 |
| BRPI0712823A2 (pt) | 2012-07-24 |
| NZ597498A (en) | 2013-06-28 |
| US8829041B2 (en) | 2014-09-09 |
| RU2009102048A (ru) | 2010-07-27 |
| CA2655604A1 (en) | 2007-12-27 |
| JP5203360B2 (ja) | 2013-06-05 |
| EP2049472A2 (en) | 2009-04-22 |
| WO2007150010A3 (en) | 2008-05-02 |
| ECSP099046A (es) | 2009-02-27 |
| MX2008016343A (es) | 2009-01-19 |
| CR10540A (es) | 2009-02-05 |
| NO20090282L (no) | 2009-03-19 |
| IL196094A0 (en) | 2009-09-01 |
| TW200808773A (en) | 2008-02-16 |
| CN101472887A (zh) | 2009-07-01 |
| NZ611323A (en) | 2014-10-31 |
| WO2007150010A2 (en) | 2007-12-27 |
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