UA99659C2 - Мультивалентна вакцина з нативних везикул зовнішньої мембрани менінгококів, способи її застосування - Google Patents

Мультивалентна вакцина з нативних везикул зовнішньої мембрани менінгококів, способи її застосування

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Publication number
UA99659C2
UA99659C2 UAA201015812A UAA201015812A UA99659C2 UA 99659 C2 UA99659 C2 UA 99659C2 UA A201015812 A UAA201015812 A UA A201015812A UA A201015812 A UAA201015812 A UA A201015812A UA 99659 C2 UA99659 C2 UA 99659C2
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UA
Ukraine
Prior art keywords
outer membrane
methods
making
membrane vesicle
native outer
Prior art date
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UAA201015812A
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English (en)
Russian (ru)
Inventor
Уенделл Девід Золлінгер
Міхаіл Донєц
Дебора Шміль
Боріс Іонін
Райан МАРКЕС
Елізабет Еллен Моран
Original Assignee
Дзе Ю.Ес.Ей., Ес Репрезентед Бай Дзе Секретарі Оф Дзе Армі, Он Бехаф Оф Уолтер Рід Армі
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Application filed by Дзе Ю.Ес.Ей., Ес Репрезентед Бай Дзе Секретарі Оф Дзе Армі, Он Бехаф Оф Уолтер Рід Армі filed Critical Дзе Ю.Ес.Ей., Ес Репрезентед Бай Дзе Секретарі Оф Дзе Армі, Он Бехаф Оф Уолтер Рід Армі
Publication of UA99659C2 publication Critical patent/UA99659C2/uk

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Даний спосіб належить до композиції вакцин, що містить нативні везикули зовнішньої мембрани менінгококів (NOMV) щонайменше з двох генетично модифікованих штамів Neisseria, що забезпечує захисний імунітет проти менінгококової інфекції, більш переважно, інфекції, що викликається менінгококами підтипу В. Заявлений спосіб також належить до способів імунізації тварини або людини проти менінгококової інфекції, що включають в себе введення вакцинної композиції за даним винаходом.
UAA201015812A 2008-05-30 2009-06-01 Мультивалентна вакцина з нативних везикул зовнішньої мембрани менінгококів, способи її застосування UA99659C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5746208P 2008-05-30 2008-05-30
PCT/US2009/045818 WO2009158142A1 (en) 2008-05-30 2009-06-01 Meningococcal multivalent native outer membrane vesicle vaccine, methods of making and use thereof

Publications (1)

Publication Number Publication Date
UA99659C2 true UA99659C2 (uk) 2012-09-10

Family

ID=41444870

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201015812A UA99659C2 (uk) 2008-05-30 2009-06-01 Мультивалентна вакцина з нативних везикул зовнішньої мембрани менінгококів, способи її застосування

Country Status (19)

Country Link
US (2) US9387239B2 (uk)
EP (1) EP2296699A4 (uk)
JP (2) JP5723768B2 (uk)
KR (1) KR20110053314A (uk)
CN (1) CN102105166A (uk)
AU (1) AU2009262893B2 (uk)
BR (1) BRPI0913268A2 (uk)
CA (1) CA2726465A1 (uk)
CO (1) CO6341569A2 (uk)
CR (1) CR11812A (uk)
DO (1) DOP2010000364A (uk)
EC (1) ECSP10010723A (uk)
IL (1) IL209660A0 (uk)
MX (1) MX2010012999A (uk)
NZ (1) NZ589812A (uk)
RU (1) RU2477145C2 (uk)
UA (1) UA99659C2 (uk)
WO (1) WO2009158142A1 (uk)
ZA (1) ZA201008548B (uk)

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Also Published As

Publication number Publication date
ZA201008548B (en) 2012-06-27
KR20110053314A (ko) 2011-05-20
IL209660A0 (en) 2011-02-28
AU2009262893A9 (en) 2015-05-21
WO2009158142A1 (en) 2009-12-30
US20170100471A1 (en) 2017-04-13
RU2010153658A (ru) 2012-08-10
NZ589812A (en) 2012-08-31
MX2010012999A (es) 2012-03-07
AU2009262893B2 (en) 2015-05-21
CO6341569A2 (es) 2011-11-21
AU2009262893A1 (en) 2009-12-30
EP2296699A4 (en) 2013-11-13
JP5723768B2 (ja) 2015-05-27
CN102105166A (zh) 2011-06-22
CA2726465A1 (en) 2009-12-30
BRPI0913268A2 (pt) 2016-03-15
US20110182942A1 (en) 2011-07-28
ECSP10010723A (es) 2011-05-31
CR11812A (es) 2011-07-06
EP2296699A1 (en) 2011-03-23
JP2011521976A (ja) 2011-07-28
JP2015061870A (ja) 2015-04-02
US9387239B2 (en) 2016-07-12
RU2477145C2 (ru) 2013-03-10
DOP2010000364A (es) 2011-07-15

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