US3011945A - Phenylcyclopropylamine -10-(omega-aminoalkyl)-phenothiazine ataractic composition - Google Patents

Phenylcyclopropylamine -10-(omega-aminoalkyl)-phenothiazine ataractic composition Download PDF

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Publication number
US3011945A
US3011945A US12917A US1291760A US3011945A US 3011945 A US3011945 A US 3011945A US 12917 A US12917 A US 12917A US 1291760 A US1291760 A US 1291760A US 3011945 A US3011945 A US 3011945A
Authority
US
United States
Prior art keywords
phenylcyclopropylamine
phenothiazine
ataractic
aminoalkyl
free base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US12917A
Other languages
English (en)
Inventor
Charles L Bolling
Carl R Stevenson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline & French Laboratories Ltd
Original Assignee
Smith Kline & French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline & French Laboratories Ltd filed Critical Smith Kline & French Laboratories Ltd
Priority to US12917A priority Critical patent/US3011945A/en
Priority to GB6764/61A priority patent/GB911229A/en
Priority to BE600835A priority patent/BE600835A/fr
Priority to FR854858A priority patent/FR981M/fr
Application granted granted Critical
Publication of US3011945A publication Critical patent/US3011945A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame

Definitions

  • a method of treating emotionally disturbed human beings in accordance with claim 10 characterized in that the trans-2-phenylcyclopropylamine sulfate and the 2- trifluoromethyl 10 [3 (1 methyl 4 piperazinyl) propyl]-phenothiazine dihydrochloride are combined with a pharmaceutical carrier.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
US12917A 1960-03-07 1960-03-07 Phenylcyclopropylamine -10-(omega-aminoalkyl)-phenothiazine ataractic composition Expired - Lifetime US3011945A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US12917A US3011945A (en) 1960-03-07 1960-03-07 Phenylcyclopropylamine -10-(omega-aminoalkyl)-phenothiazine ataractic composition
GB6764/61A GB911229A (en) 1960-03-07 1961-02-23 Improvements in or relating to ataractic compositions
BE600835A BE600835A (fr) 1960-03-07 1961-03-02 Compositions ataractiques.
FR854858A FR981M (fr) 1960-03-07 1961-03-07

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12917A US3011945A (en) 1960-03-07 1960-03-07 Phenylcyclopropylamine -10-(omega-aminoalkyl)-phenothiazine ataractic composition

Publications (1)

Publication Number Publication Date
US3011945A true US3011945A (en) 1961-12-05

Family

ID=21757361

Family Applications (1)

Application Number Title Priority Date Filing Date
US12917A Expired - Lifetime US3011945A (en) 1960-03-07 1960-03-07 Phenylcyclopropylamine -10-(omega-aminoalkyl)-phenothiazine ataractic composition

Country Status (4)

Country Link
US (1) US3011945A (fr)
BE (1) BE600835A (fr)
FR (1) FR981M (fr)
GB (1) GB911229A (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3134676A (en) * 1961-06-21 1964-05-26 Smith Kline French Lab Animal feed compositions and methods for their administration
US3177255A (en) * 1961-01-07 1965-04-06 Hoechst Ag Phenylpropylamine derivatives
US3188347A (en) * 1961-12-18 1965-06-08 Schering Corp 5(4-dimethylaminocyclohexy)-dibenzo [a, d] cyclohepta[1, 4]diene and salts thereof
US3192229A (en) * 1962-07-03 1965-06-29 Colgate Palmolive Co Phenylcyclopropyl amides
US3192207A (en) * 1963-03-11 1965-06-29 Robins Co Inc A H Aminoalkyl esters of 4-carboxyalkyl-2-pyrrolidinones and 4-carboxyalkyl-2-thionpyrrolidinones
US3221054A (en) * 1962-01-04 1965-11-30 May & Baker Ltd N-propargyl-phenoxyalkylamines
US3515785A (en) * 1958-12-06 1970-06-02 Geigy Chem Corp Compositions and methods for treating endogenous depression with 3-chloro - 5 - (gamma - dimethylamino - propyl)-iminodibenzyl
US3621097A (en) * 1970-03-30 1971-11-16 Jan Marcel Didier Aron Samuel Method and compositions for treatment of mental illness
WO2016210292A1 (fr) 2015-06-25 2016-12-29 Children's Medical Center Corporation Procédés et compositions se rapportant à l'expansion, l'enrichissement et la conservation de cellules souches hématopoïétiques
WO2017161001A1 (fr) 2016-03-15 2017-09-21 Children's Medical Center Corporation Procédés et compositions concernant l'expansion de cellules souches hématopoïétiques

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444789A (en) * 1980-05-30 1984-04-24 University Of Georgia Research Foundation, Inc. Use of 8-anilino-1-naphthalenesulfonate as a vaginal contraceptive

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3515785A (en) * 1958-12-06 1970-06-02 Geigy Chem Corp Compositions and methods for treating endogenous depression with 3-chloro - 5 - (gamma - dimethylamino - propyl)-iminodibenzyl
US3177255A (en) * 1961-01-07 1965-04-06 Hoechst Ag Phenylpropylamine derivatives
US3134676A (en) * 1961-06-21 1964-05-26 Smith Kline French Lab Animal feed compositions and methods for their administration
US3188347A (en) * 1961-12-18 1965-06-08 Schering Corp 5(4-dimethylaminocyclohexy)-dibenzo [a, d] cyclohepta[1, 4]diene and salts thereof
US3221054A (en) * 1962-01-04 1965-11-30 May & Baker Ltd N-propargyl-phenoxyalkylamines
US3192229A (en) * 1962-07-03 1965-06-29 Colgate Palmolive Co Phenylcyclopropyl amides
US3192207A (en) * 1963-03-11 1965-06-29 Robins Co Inc A H Aminoalkyl esters of 4-carboxyalkyl-2-pyrrolidinones and 4-carboxyalkyl-2-thionpyrrolidinones
US3621097A (en) * 1970-03-30 1971-11-16 Jan Marcel Didier Aron Samuel Method and compositions for treatment of mental illness
WO2016210292A1 (fr) 2015-06-25 2016-12-29 Children's Medical Center Corporation Procédés et compositions se rapportant à l'expansion, l'enrichissement et la conservation de cellules souches hématopoïétiques
WO2017161001A1 (fr) 2016-03-15 2017-09-21 Children's Medical Center Corporation Procédés et compositions concernant l'expansion de cellules souches hématopoïétiques
EP4049665A1 (fr) 2016-03-15 2022-08-31 Children's Medical Center Corporation Procédés et compositions associées à l'expansion de cellules souches hématopoïétiques

Also Published As

Publication number Publication date
GB911229A (en) 1962-11-21
BE600835A (fr) 1961-09-04
FR981M (fr) 1961-12-04

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