Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
  • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
  • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
  • A61L2/18—Liquid substances
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
  • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
  • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
  • A01N43/20—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom three- or four-membered rings

Definitions

• the present invention relates to a process for sterilizing surgical sutures, especially catgut or other synthetic surgical sutures with or without needles by means of ethylene oxide or propylene oxide in alcoholic solution.
• aliphatic saturated or unsaturated monoor di-carboxylic acids, or aromatic monoor di-carboxylic acids, aromatic phenol carboxylic acids, and organic bases such as alkylolamines or alkylamines are added to or admixed with the alcoholic solution.
• Still a further object of the present invention resides in the provision of a method for sterilizing surgical sutures or the like which utilizes relatively inexpensive ingredients to affect a high degree of sterilization.
• a further object of the present invention resides in the provision of a sterilization method and solution suitable therefor which does not require high temperatures for realizing a high degree of sterilization.
• Example I 130 ml. of a solution consisting of:
• Example II 130 ml. of a solution consisting of:
• water is added up to a total composition of 0.5 by weight of either benzene carboxylic acid or salicylic acid, brought to a pH factor of 6.5 by means of a base, is poured into a bottle which contains the suture material to be sterilized, and is left for 14 days at a temperature of 25 C.
• Example III ml. of a solution consisting of:
• water is added up to a total composition of 100% adjusted with triethanolamine to a pH factor of 6.8, is poured into a bottle which contains the suture material to be sterilized, and is left standing for 7 days at a temperature of about 30 C.
• Example IV Suture material of diameter 1 (according to USP XVI) is treated for about one day with a solution consisting of:
• the acids may consist of any saturated (such as acetic acid) or unsaturated monocarboxylic acids or di-carboxylic acids, aromatic monocarboxylic acids, di-carboxylic acids or aromatic phenol carboxylic acids or mixtures thereof.
• Any suitable organic base may be used for the present invention such as, for instance, alkylolamines or alkylamines.
• a method for sterilizing surgical sutures such as catgut or synthetic surgical sutures with or without needles which comprises immersing the sutures into an alcoholic solution containing a small quantity of an epoxide sterilizing agent, a small amount of an acid selected from the group consisting of aliphatic saturated and unsaturated monocarboxylic acids and di-carboxylic acids and aromatic mono-carboxylic acids and dicarboxylic acids and a base present in an amount sufficient to approximately neutralize the acid, said base being selected from the group consisting of alkylamines and alkylolamines, and leaving the sutures in the solution at about room temperature for a predetermined time.
• a solution for sterilizing surgical sutures such as catgut or synthetic surgical sutures with or without needles which comprises an aqueous alcohol solution, a small quantity of an epoxide sterilizing agent, a small amount of an acid selected from the group consisting of acetic acid, succinic acid, sorbic acid, benzoic acid, and salicylic acid and a base present in an amount sufiicient to approximately neutralize the acid, said base being selected from the group consisting of alkylamines and alkylolamines.
• a solution for sterilizing surgical sutures such as catgut or synthetic surgical sutures with or without needles which comprises an aqueous alcohol solution, a small quantity of an epoxide sterilizing agent, a small amount of an acid selected from the group consisting of aliphatic saturated and unsaturated monocarboxylic acids and dicarboxylic acids and aromatic mono-carboxylic acids and dicarboxylic acids and a base present in an amount sufficient to approximately neutralize the acid, said base being selected from the group consisting of alkylamines and al-kylolamines.
• a solution according to claim 5, wherein said acid is succinic acid.
• a solution according to claim 5, wherein said acid is salicylic acid.

Landscapes

• Life Sciences & Earth Sciences (AREA)
• Health & Medical Sciences (AREA)
• General Health & Medical Sciences (AREA)
• Environmental Sciences (AREA)
• Chemical Kinetics & Catalysis (AREA)
• Engineering & Computer Science (AREA)
• Dentistry (AREA)
• Pest Control & Pesticides (AREA)
• Wood Science & Technology (AREA)
• Zoology (AREA)
• Agronomy & Crop Science (AREA)
• Chemical & Material Sciences (AREA)
• Plant Pathology (AREA)
• General Chemical & Material Sciences (AREA)
• Epidemiology (AREA)
• Animal Behavior & Ethology (AREA)
• Public Health (AREA)
• Veterinary Medicine (AREA)
• Agricultural Chemicals And Associated Chemicals (AREA)
• Apparatus For Disinfection Or Sterilisation (AREA)

Applications Claiming Priority (1)

Publications (1)

Family

ID=7372135

Family Applications (1)

Country Status (3)

Cited By (2)

Citations (4)

• 1963
  • 1963-01-31 DE DE19631492425 patent/DE1492425A1/de not_active Withdrawn
• 1964
  • 1964-01-29 NL NL6400695A patent/NL6400695A/xx unknown
  • 1964-01-29 US US341115A patent/US3414370A/en not_active Expired - Lifetime

Patent Citations (4)

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