UY34285A - Nuevos sulfóxidos de piperidino-dihidrotienopirimidina y su uso para tratar epoc y asma - Google Patents

Nuevos sulfóxidos de piperidino-dihidrotienopirimidina y su uso para tratar epoc y asma

Info

Publication number
UY34285A
UY34285A UY0001034285A UY34285A UY34285A UY 34285 A UY34285 A UY 34285A UY 0001034285 A UY0001034285 A UY 0001034285A UY 34285 A UY34285 A UY 34285A UY 34285 A UY34285 A UY 34285A
Authority
UY
Uruguay
Prior art keywords
asthma
piperidine
new
dihydrotienopirimidine
sulphoxides
Prior art date
Application number
UY0001034285A
Other languages
English (en)
Inventor
Kim Soojin
Bing-Shiou Yang
Werthmann Ulrike
Pascale A J Pouzet
Nickolaus Peter
Rogelio P Frutos
Jason Alan Mulder
Patel Nitinchandra
Chris H Senanayake
Thomas G Tampone
Wei Xudong
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46924393&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY34285(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of UY34285A publication Critical patent/UY34285A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A61P11/02—Nasal agents, e.g. decongestants
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    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
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    • C07B2200/13—Crystalline forms, e.g. polymorphs
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se divulgan nuevos sulfóxidos de piperidino-dihidrotienopirimidina de fórmula I, en donde los sustituyentes A, R y S*, son tales como se describen en la memoria y en las reivindicaciones correspondientes, y todas las sales aceptables para uso farmacéutico, enantiómeros y racematos, hidratos y solvatos de los mismos, y el uso de estos compuestos para el tratamiento de enfermedades inflamatorias o alérgicas del tracto respiratorio tales como EPOC o asma.
UY0001034285A 2011-08-24 2012-08-23 Nuevos sulfóxidos de piperidino-dihidrotienopirimidina y su uso para tratar epoc y asma UY34285A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161526861P 2011-08-24 2011-08-24

Publications (1)

Publication Number Publication Date
UY34285A true UY34285A (es) 2013-02-28

Family

ID=46924393

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001034285A UY34285A (es) 2011-08-24 2012-08-23 Nuevos sulfóxidos de piperidino-dihidrotienopirimidina y su uso para tratar epoc y asma

Country Status (27)

Country Link
US (3) US20130059866A1 (es)
EP (1) EP2748156B1 (es)
JP (1) JP5851038B2 (es)
KR (1) KR101959194B1 (es)
CN (1) CN103889970B (es)
AP (1) AP2014007401A0 (es)
AR (2) AR087655A1 (es)
AU (1) AU2012298599B2 (es)
BR (2) BR112014003378B1 (es)
CA (1) CA2846183C (es)
CL (1) CL2014000296A1 (es)
CO (1) CO6900138A2 (es)
DK (1) DK2748156T5 (es)
EA (1) EA024033B1 (es)
EC (1) ECSP14013254A (es)
ES (1) ES2563028T3 (es)
HU (1) HUE028531T2 (es)
IL (1) IL230592A0 (es)
MX (1) MX358651B (es)
PE (1) PE20141532A1 (es)
PH (1) PH12014500395A1 (es)
PL (1) PL2748156T4 (es)
TN (1) TN2014000081A1 (es)
TW (1) TWI597283B (es)
UY (1) UY34285A (es)
WO (1) WO2013026797A1 (es)
ZA (1) ZA201400792B (es)

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KR20250046278A (ko) 2022-08-09 2025-04-02 시젱 하이스코 파마수티칼 씨오., 엘티디. Pde4b 억제제 및 이의 용도
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US20130059866A1 (en) 2013-03-07
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TN2014000081A1 (en) 2015-07-01
US20130079359A1 (en) 2013-03-28
EA201400252A1 (ru) 2014-12-30
EP2748156B1 (en) 2015-12-16
BR112014003378B1 (pt) 2022-05-17
MX2014002025A (es) 2014-03-27
PE20141532A1 (es) 2014-10-31
KR101959194B1 (ko) 2019-03-19
BR112014003378A2 (pt) 2017-03-01
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AU2012298599A1 (en) 2014-02-13
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US9150586B2 (en) 2015-10-06
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