UY37155A - Inhibidores de ret - Google Patents

Inhibidores de ret

Info

Publication number
UY37155A
UY37155A UY0001037155A UY37155A UY37155A UY 37155 A UY37155 A UY 37155A UY 0001037155 A UY0001037155 A UY 0001037155A UY 37155 A UY37155 A UY 37155A UY 37155 A UY37155 A UY 37155A
Authority
UY
Uruguay
Prior art keywords
compounds
ret inhibitors
ret
inhibitors
methods
Prior art date
Application number
UY0001037155A
Other languages
English (en)
Inventor
D Brubaker Jason
L Kim Joseph
J Wilson Kevin
Original Assignee
Blueprint Medicines Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blueprint Medicines Corp filed Critical Blueprint Medicines Corp
Publication of UY37155A publication Critical patent/UY37155A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

En la presente memoria se describen compuestos que inhiben a RET de tipo silvestre y sus mutantes resistentes, composiciones farmacéuticas que incluyen a dichos compuestos, y métodos para utilizar dichos compuestos y composiciones.
UY0001037155A 2016-03-17 2017-03-17 Inhibidores de ret UY37155A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662309748P 2016-03-17 2016-03-17

Publications (1)

Publication Number Publication Date
UY37155A true UY37155A (es) 2017-10-31

Family

ID=58428429

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001037155A UY37155A (es) 2016-03-17 2017-03-17 Inhibidores de ret

Country Status (5)

Country Link
US (1) US10183928B2 (es)
AR (1) AR107912A1 (es)
TW (1) TW201738228A (es)
UY (1) UY37155A (es)
WO (1) WO2017161269A1 (es)

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DK3395814T3 (da) 2013-10-25 2022-07-04 Blueprint Medicines Corp Hæmmere af fibroblastvækstfaktorreceptoren
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NZ742351A (en) 2015-11-02 2023-03-31 Blueprint Medicines Corp Inhibitors of ret
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UY37155A (es) 2016-03-17 2017-10-31 Blueprint Medicines Corp Inhibidores de ret
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WO2020083332A1 (zh) * 2018-10-24 2020-04-30 南京明德新药研发有限公司 作为ret抑制剂的嘧啶衍生物
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CN111285882B (zh) * 2018-12-07 2022-12-02 四川科伦博泰生物医药股份有限公司 稠环化合物、包含其的药物组合物及其制备方法和用途
CN111484479B (zh) * 2019-01-25 2023-06-13 四川科伦博泰生物医药股份有限公司 氮杂环化合物、包含其的药物组合物及其制备方法和用途
CN111499613B (zh) * 2019-01-31 2023-05-12 浙江海正药业股份有限公司 N-甲酰胺衍生物、其制备方法及其在医药上的用途
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CN111961034A (zh) * 2019-05-20 2020-11-20 浙江同源康医药股份有限公司 用作ret激酶抑制剂的化合物及其应用
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MX2018006195A (es) 2015-11-19 2018-09-05 Blueprint Medicines Corp Compuestos y composiciones utiles para el tratamiento de trastornos relacionados con ntrk.
UY37155A (es) 2016-03-17 2017-10-31 Blueprint Medicines Corp Inhibidores de ret
FI3442977T3 (fi) 2016-04-15 2023-09-26 Blueprint Medicines Corp Aktiviinireseptorin kaltaisen kinaasin estäjät
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Also Published As

Publication number Publication date
US10183928B2 (en) 2019-01-22
WO2017161269A1 (en) 2017-09-21
US20170267661A1 (en) 2017-09-21
AR107912A1 (es) 2018-06-28
TW201738228A (zh) 2017-11-01

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