WO1993014792A1 - Liquides desinfectant/nettoyant et hydratant pour verres de contact, et leur utilisation - Google Patents

Liquides desinfectant/nettoyant et hydratant pour verres de contact, et leur utilisation Download PDF

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Publication number
WO1993014792A1
WO1993014792A1 PCT/FI1992/000025 FI9200025W WO9314792A1 WO 1993014792 A1 WO1993014792 A1 WO 1993014792A1 FI 9200025 W FI9200025 W FI 9200025W WO 9314792 A1 WO9314792 A1 WO 9314792A1
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WO
WIPO (PCT)
Prior art keywords
fluid
equivalent
contact lenses
disinfecting
known art
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FI1992/000025
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English (en)
Inventor
Mauno Sakari Reiala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to PCT/FI1992/000025 priority Critical patent/WO1993014792A1/fr
Priority to EP19920904267 priority patent/EP0588795A1/fr
Priority to AU12023/92A priority patent/AU1202392A/en
Publication of WO1993014792A1 publication Critical patent/WO1993014792A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/12—Non-macromolecular oxygen-containing compounds, e.g. hydrogen peroxide or ozone

Definitions

  • the objects of the invention are a disinfecting-cleansing fluid and a moisturising fluid for contact lenses and their use.
  • a known art disinfectant used in the aforementioned maintenance of contact lenses is a hydrogen peroxide solution of about three percent. This substance irritates the eye and it must always be neutralised and removed from the lens by means of a separate neutralising agent during a maintenance stage that takes about ten minutes to carry out.
  • the disadvantage is that small amounts of the said substance are retained in the lens pores.
  • the neutralisation and the lens maintenance necessary because of the possible remnants of storage substances in the lens must be performed daily.
  • the experience with lenses worn overnight is that the user is unable to see with the dry lenses because of the reduced nighttime secretion of lacrimal fluid.
  • the practice has been for contact lenses to be removed for the night and to be stored in a container of storage fluid.
  • a contact lens is a partial obstacle to the entry of oxygen to dissolve into the lacrimal fluid behind the lens and attempts have been made to avoid this problem by manufacturing lenses to be of 55 - 70 percent porosity instead of the known art 40 percent porosity.
  • Tiny amounts of hydrogen peroxide have been transferred with the lenses onto the eyes.
  • Another inconvenience connected to contact lenses has been the experience that they are not so well suited for older and busy people. They have been troublesome to wear in dusty conditions and in sports that induce heavy perspiration. In both of these situations the lenses have to be occasionally removed for cleansing purposes and this is bothersome.
  • boracic acid solution disinfects the eyes and is composed of sterile water containing boracic acid, collyrium boricum (2 percent or 20 mg/ml) and phenylhydrarg.nitr. 0.01 mg/ml.
  • Oxygen may be dissolved in water just like it can be dissolved in a solution of boracic acid in the same manner as is used with indoor aquariums by blowing bubbles of air into it.
  • the lens of the eye has no blood veins and gets its nourishment from the surrounding chamber fluid. Fish in an aquarium do well when a continuous stream of air is blown into the water so that the oxygen concentration in the water is about 10-20 mg/1.
  • Contact lens storage fluid for storing soft contact lenses in a container is known on the basis of EP patent application 95524.
  • the said storage fluid contains relatively large amounts of sodium chloride, boracic acid and borax as is required by container storage. No oxygen has been dissolved in the said storage fluid.
  • a cleansing-rubbing solution for the purpose of removing deposits from the surfaces of hard and soft contact lenses is known on the basis of EP patent application 279 378.
  • This substance contains small particles that remove dirt.
  • the solution may as such contain boracic acid along with many other substances. This solution must not come into contact with the eyes.
  • FI patent 62463 describes a method whereby the hydrogen peroxide is disintegrated from contact lenses disinfected in a container by means of the same treatment by hydrogen peroxide and the said hydrogen peroxide is then removed using a catalyst made of metals. The solution containing the catalyst must not come into contact with the eyes.
  • FI patent publication 85816 describes the contact lens disinfec ⁇ ting-cleansing fluid and how it is used.
  • the cornea of the eye is no longer irritated by the daily putting into position of the contact lenses, and since there is no longer hydrogen peroxide to be retained in contact lens pores, and since dirty air is no longer sucked into bottles of rinsing fluid and bacteria are thus eliminated from coming into contact with contact lenses, and since disinfecting of the lenses now takes place by the lens pores being partially evacuated and then being refilled with mildly disinfecting fluid, and since oxygen deficiency underneath the lenses is reduced, the wearing of contact lenses results in less or no risk at all of eye ailments such as keratitis as compared to the situation before.
  • the purpose of the invention is to bring about such a disinfec ⁇ ting-cleansing fluid for contact lenses as will enable contact lenses to be daily disinfected and cleaned and any protein contained by them to be removed without the user ever needing to remove the lenses from the eyes, and so that all the afore ⁇ mentioned contact lens disadvantages as well the possible risk of the lenses causing eye ailments can be minimised or altoget ⁇ her eliminated.
  • the purpose of the invention is to bring about the use of the disinfecting-cleansing fluid.
  • a further purpose of the invention is also to bring about an improved moisturising fluid suitable for contact lenses and the use of the said fluid.
  • Yet another purpose of the invention is to bring about such a drop bottle for the aforementioned fluids as will not suck in unclean air.
  • the disinfecting-cleansing fluid in accordance with the invention is as follows:
  • It is composed of a 2 percent solution of as such known art boracic acid solution eye lotion into which oxygen has been dissolved using a method as such of known art so that the oxygen content in the said solution is c. 0.001 - 0.002 % or c. 10 - 20 mg/1.
  • the use of the fluid for disinfecting and cleansing of and removing of protein from contact lenses without it being necessary for the lens to be removed from the eyes is such that drops of the said fluid are caused to fall onto contact lenses kept permanently on the eyes at the moment the user opens his/her eyes on awakening.
  • the disinfecting-cleansing fluid may be composed to function as the moisturising fluid for contact lenses.
  • An example of such use is in the evening so that the said fluid contains as such known art eye moisturising fluid whose active components are: Duasorb, benzalkon.chloride 0.01 %, sod.edet. 0.05 %, or equivalent, c. 10 - 40 %, and it is cleaned away from contact lenses in accordance with claim 2.
  • the drop bottle for the said fluids or equivalent can be formed of as such known art disposable syringe or equivalent so that the syringe is filled with the said fluid or equivalent in the course of factory manufacturing or equivalent and so that it is provided with a stopper or equivalent.
  • the disinfecting-cleansing fluid for contact lenses was made by blowing as such known art medical inhalation air through a gas sterilising filter into a 2 % solution of boracic acid eye lotion.
  • the amount of oxygen dissolved in the liquid came to be c. 0.002 %.
  • Examples of other gases contained by the inhalation air and dissolved into the liquid were nitrogen and argon.
  • the contact lenses were as such known art hydrophilic polymer lenses with 62 % phemfilcon A and 38 % water.
  • the contact lenses were worn continuously on the eyes for a period of over a year and even further without the lenses being removed during the period.
  • the disinfecting-cleansing of the contact lenses was carried out according to user instructions.
  • the fluid dropped onto the eyes in the morning filled the partially evacuated lens pores and the lens base during the night and disinfected and cleansed the lens on all sides and softened the lens into normal softness within c. 4 seconds.
  • Contact lenses such as those used in the example, for example, can be worn on the eyes continuously for a period of one year by using a disinfecting-cleansing fluid in accordance with the patent claim in the manner described in the user instructions.
  • the results obtained so far indicate that a person can wear contact lenses in this manner for his entire lifetime.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Eyeglasses (AREA)

Abstract

Liquide désinfectant/nettoyant pour verres de contact constitué d'une lotion ophtalmique connue en soi comportant une solution de 2 % environ d'acide borique, ou analogue, et dans lequel on a dissous de 0,001 à 0,002 % environ ou de 10 à 20 mg/l environ d'oxygène à l'aide d'un procédé connu en soi, par exemple le soufflage d'air. L'utilisation dudit liquide est telle que, dès que l'utilisateur ouvre les yeux, des gouttes dudit liquide ou du liquide analogue tombent sur les verres de contact destinés à être portés en permanence. Le liquide désinfectant/nettoyant peut également servir de liquide hydratant pour verres de contact, que l'on peut utiliser par exemple lorsqu'on regarde la télévision le soir. Dans ce cas, le liquide contient un liquide hydratant ophtalmique connu en soi dont les ingrédients actifs sont le Duasorb, le chlorure de benzalkonium constituant 0,01 %, et l'édétate de sodium constituant 0,05 %, ou un liquide hydratant analogue constituant de 10 à 40 % environ. En outre, le liquide hydratant est enlevé des verres conformément à la revendication no. 2, ou de manière analogue. Un flacon distributeur de gouttelettes des liquides précités peut être constitué d'une seringue jetable connue en soi ou analogue, la seringue étant remplie dudit liquide ou du liquide analogue lors de sa fabrication dans l'usine, ou de manière analogue, et ledit flacon étant pourvu d'un bouchon ou analogue.
PCT/FI1992/000025 1992-01-30 1992-01-30 Liquides desinfectant/nettoyant et hydratant pour verres de contact, et leur utilisation Ceased WO1993014792A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PCT/FI1992/000025 WO1993014792A1 (fr) 1992-01-30 1992-01-30 Liquides desinfectant/nettoyant et hydratant pour verres de contact, et leur utilisation
EP19920904267 EP0588795A1 (fr) 1992-01-30 1992-01-30 Liquides desinfectant/nettoyant et hydratant pour verres de contact, et leur utilisation
AU12023/92A AU1202392A (en) 1992-01-30 1992-01-30 A disinfecting-cleansing fluid and moisturising fluid for contact lenses and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/FI1992/000025 WO1993014792A1 (fr) 1992-01-30 1992-01-30 Liquides desinfectant/nettoyant et hydratant pour verres de contact, et leur utilisation

Publications (1)

Publication Number Publication Date
WO1993014792A1 true WO1993014792A1 (fr) 1993-08-05

Family

ID=8556526

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI1992/000025 Ceased WO1993014792A1 (fr) 1992-01-30 1992-01-30 Liquides desinfectant/nettoyant et hydratant pour verres de contact, et leur utilisation

Country Status (3)

Country Link
EP (1) EP0588795A1 (fr)
AU (1) AU1202392A (fr)
WO (1) WO1993014792A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006089108A3 (fr) * 2005-02-17 2007-05-31 Oxyband Technologies Inc Procede et appareil d'alimentation d'une zone en gaz

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0095524A1 (fr) * 1982-06-01 1983-12-07 Hoya Lens Corporation Composition pour la conservation de lentilles de contact souples
DE3524407A1 (de) * 1985-07-09 1987-01-15 Erwin Sander Elektroapparateba Einrichtung zur sterilisation von kontaktlinsen mit ozon

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0095524A1 (fr) * 1982-06-01 1983-12-07 Hoya Lens Corporation Composition pour la conservation de lentilles de contact souples
DE3524407A1 (de) * 1985-07-09 1987-01-15 Erwin Sander Elektroapparateba Einrichtung zur sterilisation von kontaktlinsen mit ozon

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006089108A3 (fr) * 2005-02-17 2007-05-31 Oxyband Technologies Inc Procede et appareil d'alimentation d'une zone en gaz
JP2008529739A (ja) * 2005-02-17 2008-08-07 オキシバンド テクノロジーズ インコーポレイテッド ガスをエリアに供給する方法および装置

Also Published As

Publication number Publication date
AU1202392A (en) 1993-09-01
EP0588795A1 (fr) 1994-03-30

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