WO2001041776A3 - Use of honey in medical dressings - Google Patents

Use of honey in medical dressings Download PDF

Info

Publication number
WO2001041776A3
WO2001041776A3 PCT/NZ2000/000248 NZ0000248W WO0141776A3 WO 2001041776 A3 WO2001041776 A3 WO 2001041776A3 NZ 0000248 W NZ0000248 W NZ 0000248W WO 0141776 A3 WO0141776 A3 WO 0141776A3
Authority
WO
WIPO (PCT)
Prior art keywords
honey
viscosity increasing
medical dressings
gels
honeys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/NZ2000/000248
Other languages
French (fr)
Other versions
WO2001041776B1 (en
WO2001041776A2 (en
Inventor
Peter Molan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WaikatoLink Ltd
Original Assignee
WaikatoLink Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26652142&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2001041776(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from NZ50168799A external-priority patent/NZ501687A/en
Priority to DE60008790T priority Critical patent/DE60008790T3/en
Priority to JP2001543121A priority patent/JP2003516357A/en
Application filed by WaikatoLink Ltd filed Critical WaikatoLink Ltd
Priority to EP00981937A priority patent/EP1237561B2/en
Priority to US10/149,116 priority patent/US6956144B2/en
Priority to AT00981937T priority patent/ATE260669T1/en
Priority to AU19038/01A priority patent/AU781878B2/en
Priority to US12/420,344 priority patent/USRE42755E1/en
Priority to CA002397614A priority patent/CA2397614C/en
Publication of WO2001041776A2 publication Critical patent/WO2001041776A2/en
Publication of WO2001041776A3 publication Critical patent/WO2001041776A3/en
Publication of WO2001041776B1 publication Critical patent/WO2001041776B1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention is directed to the use of honey in medical dressings. Preferred embodiments modify honey with a viscosity increasing agent, resulting in a range of possible compositions including ointments and salves, self-adhesive gels such as for use on mouth ulcers and pustules, and pliable or flexible sheets which can be used as a wound covering. Preferred viscosity increasing agents include both particulate and continuous gels, respective examples of each including agars and alginates. Selected honeys preferably, but not necessarily, exhibit antibacterial properties other than what is merely conferred by osmolarity and sugar concentration effects.
PCT/NZ2000/000248 1999-12-09 2000-12-11 Use of honey in medical dressings Ceased WO2001041776A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
US12/420,344 USRE42755E1 (en) 1999-12-09 2000-12-11 Honey based wound dressing
JP2001543121A JP2003516357A (en) 1999-12-09 2000-12-11 Honey-based medical dressing
CA002397614A CA2397614C (en) 1999-12-09 2000-12-11 Honey based wound dressing
DE60008790T DE60008790T3 (en) 1999-12-09 2000-12-11 MEDICAL ASSOCIATIONS CONTAINING LOVELY HONEY
EP00981937A EP1237561B2 (en) 1999-12-09 2000-12-11 Medical dressings comprising gelled honey
US10/149,116 US6956144B2 (en) 1999-12-09 2000-12-11 Honey based wound dressing
AT00981937T ATE260669T1 (en) 1999-12-09 2000-12-11 MEDICAL DRESSES CONTAINING JELLY HONEY
AU19038/01A AU781878B2 (en) 1999-12-09 2000-12-11 Use of honey in medical dressings

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NZ50168799A NZ501687A (en) 1999-12-09 1999-12-09 A medical composition comprising a combination of one or more honeys with one or more gelling agents to form a pliable solid
NZ501687 1999-12-09
NZ50174899 1999-12-13
NZ501748 1999-12-13

Publications (3)

Publication Number Publication Date
WO2001041776A2 WO2001041776A2 (en) 2001-06-14
WO2001041776A3 true WO2001041776A3 (en) 2001-11-08
WO2001041776B1 WO2001041776B1 (en) 2002-02-28

Family

ID=26652142

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NZ2000/000248 Ceased WO2001041776A2 (en) 1999-12-09 2000-12-11 Use of honey in medical dressings

Country Status (10)

Country Link
US (2) USRE42755E1 (en)
EP (1) EP1237561B2 (en)
JP (2) JP2003516357A (en)
CN (1) CN1409636A (en)
AT (1) ATE260669T1 (en)
AU (1) AU781878B2 (en)
CA (1) CA2397614C (en)
DE (1) DE60008790T3 (en)
ES (1) ES2217000T5 (en)
WO (1) WO2001041776A2 (en)

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US20070009586A1 (en) * 2000-02-29 2007-01-11 Cohen Kelman I Wound dressings containing complexes of transition metals and alginate for elastase sequestering
NZ505514A (en) * 2000-06-30 2003-02-28 Bee & Herbal New Zealand Ltd Method of manufacturing a wound dressing for the application of honey
GB0110715D0 (en) * 2001-05-02 2001-06-27 Acordis Speciality Fibres Ltd Wound dressing
GB2382527A (en) * 2001-12-03 2003-06-04 Acordis Speciality Fibres Ltd Wound dressings
WO2004091537A2 (en) * 2003-04-14 2004-10-28 Fmc Corporation Process for making gel films
PT1757309E (en) * 2004-04-28 2013-05-07 Hisamitsu Pharmaceutical Co Adhesive material
NZ533121A (en) * 2004-05-21 2006-02-24 Apimed Medical Honey Ltd Wound dressing comprising adhesive portions linked by non-elastic threads, and a treatment composition positioned between the adhesive portions
NZ542258A (en) * 2005-09-06 2010-05-28 Comvita New Zealand Ltd A medical composition comprising honey or sugar syrup and a viscosity increasing agent for use on wounds
JP4990150B2 (en) * 2005-09-20 2012-08-01 久光製薬株式会社 Patch
US8632810B2 (en) * 2005-10-26 2014-01-21 Medihoney Pty Ltd. Hydrocolloid composition
US20070098671A1 (en) * 2005-11-02 2007-05-03 Martin Gregory D Composition and method of treatment for irritated skin
DE202005019670U1 (en) 2005-12-14 2006-04-27 Riesinger, Birgit Wound treatment device with elastically deformable negative pressure generating element
FR2899479B1 (en) * 2006-04-10 2009-07-24 Agelys Lab CICATRISANTE COMPOSITION
US8568790B2 (en) * 2006-05-31 2013-10-29 Medihoney Pty Ltd. Medicinal compositions containing honey
US20100049262A1 (en) * 2006-11-20 2010-02-25 Puchek Daniel R Method of treating a severe diabetic ulcer
WO2008117019A1 (en) * 2007-03-24 2008-10-02 University College Cardiff Consultants Limited Tlr4 ligand isolated from honey
JP5313132B2 (en) * 2007-04-16 2013-10-09 喜久二 山口 Helicobacter pylori disinfectant
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KR101242579B1 (en) * 2010-09-20 2013-03-19 한국원자력연구원 Preparing method of Gel paste for treatment an ulcer including a honey by radiation and Gel paste for treatment an ulcer thereby
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ITMI20120180A1 (en) * 2012-02-09 2013-08-10 Marco Gandini COMPOSITION FOR THE PREVENTION OF POST-OPERATIVE ADHERENCE
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US9107974B2 (en) 2013-07-11 2015-08-18 Links Medical Products, Inc Honey impregnated composite dressing having super absorbency and intelligent management of wound exudate and method of making same
US20150030688A1 (en) * 2013-07-25 2015-01-29 Saint Louis University Honey and growth factor eluting scaffold for wound healing and tissue engineering
DK3041488T3 (en) 2013-09-02 2020-05-18 Honeylab Ltd HONEY FORMATIONS
US10086017B2 (en) * 2013-09-19 2018-10-02 Medline Industries, Inc. Wound dressing containing polysaccharides
US10342891B2 (en) 2013-09-19 2019-07-09 Medline Industries, Inc. Wound dressing containing saccharide and collagen
GB2519072B (en) * 2013-10-07 2019-12-04 Welland Medical Ltd Composition comprising collagen and honey
GB2522416B (en) * 2014-01-22 2020-07-22 Welland Medical Ltd Flange extender comprising honey
EP3245871A1 (en) * 2014-04-30 2017-11-22 Matoke Holdings Limited Antimicrobial compositions
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ES2995038T3 (en) 2017-12-06 2025-02-05 Univ Cornell Manually-operated negative pressure wound therapy (npwt) bandage with improved pump efficiency, automatic pressure indicator and automatic pressure limiter
IL270762B (en) * 2019-11-19 2021-10-31 Sion Biotext Medical Ltd A dressing that includes a combination of hydrogel and honey, a method of preparation and the uses of the dressing
WO2021188651A1 (en) 2020-03-19 2021-09-23 Friedman Joel M Novel approach to sustained production and delivery of nitric oxide and s-nitrosothiols
US12059493B2 (en) 2020-11-09 2024-08-13 Albert Einstein College Of Medicine Transdermal delivery formulations
EP4240365A4 (en) 2020-11-09 2024-07-10 Albert Einstein College of Medicine FORMULATIONS FOR TRANSDERMAL ADMINISTRATION
US12151019B2 (en) 2020-11-09 2024-11-26 Albert Einstein College Of Medicine Compositions for blood storage and transfusions
US12605332B2 (en) 2020-11-09 2026-04-21 Albert Einstein College Of Medicine Transdermal delivery formulations
US12419917B2 (en) 2021-04-23 2025-09-23 Ndal Mfg Inc Compositions and methods for treatment of conditions using fractionated honey
CN113318129A (en) * 2021-06-24 2021-08-31 中国人民大学 Efficient antibacterial honey paste and preparation method thereof
US11786712B2 (en) 2021-08-30 2023-10-17 Albert Einstein College Of Medicine Nitric oxide-releasing device
TW202608461A (en) * 2024-08-27 2026-03-01 高雄醫學大學 Pharmaceutical composition including royal jelly extracellular vesicles and the use thereof

Citations (6)

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Publication number Priority date Publication date Assignee Title
EP0355536A2 (en) * 1988-08-13 1990-02-28 LTS Lohmann Therapie-Systeme GmbH & Co. KG Flexible hydrophilic gel film, process for its preparation and use
EP0460588A1 (en) * 1990-06-07 1991-12-11 LTS LOHMANN THERAPIE-SYSTEME GmbH & CO.KG Manufacture process of fast-desintegrating film-formed administration forms
WO1997036501A1 (en) * 1996-04-02 1997-10-09 Byron Australia Pty. Ltd. Spreadable gelled food product
EP0909557A1 (en) * 1997-10-13 1999-04-21 L'oreal Use of honey as an agent for decreasing micro-organisms adhesion
WO1999055349A1 (en) * 1998-04-24 1999-11-04 Suleiman Dado Substance mixture for topical application comprising olive oil and honey
US5980875A (en) * 1996-04-12 1999-11-09 Mousa; Mahmoud A. Honey preparations

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Publication number Priority date Publication date Assignee Title
EP0355536A2 (en) * 1988-08-13 1990-02-28 LTS Lohmann Therapie-Systeme GmbH & Co. KG Flexible hydrophilic gel film, process for its preparation and use
EP0460588A1 (en) * 1990-06-07 1991-12-11 LTS LOHMANN THERAPIE-SYSTEME GmbH & CO.KG Manufacture process of fast-desintegrating film-formed administration forms
WO1997036501A1 (en) * 1996-04-02 1997-10-09 Byron Australia Pty. Ltd. Spreadable gelled food product
US5980875A (en) * 1996-04-12 1999-11-09 Mousa; Mahmoud A. Honey preparations
EP0909557A1 (en) * 1997-10-13 1999-04-21 L'oreal Use of honey as an agent for decreasing micro-organisms adhesion
WO1999055349A1 (en) * 1998-04-24 1999-11-04 Suleiman Dado Substance mixture for topical application comprising olive oil and honey

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Title
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MOLAN P C ET AL: "The effects of gamma-irradiation on the antibacterial activity of honey.", JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 48, no. 11, 1996, pages 1206 - 1209, XP000994783, ISSN: 0022-3573 *

Also Published As

Publication number Publication date
DE60008790T2 (en) 2005-03-10
ES2217000T3 (en) 2004-11-01
ES2217000T5 (en) 2009-10-01
US20040054313A1 (en) 2004-03-18
EP1237561B2 (en) 2009-04-22
AU1903801A (en) 2001-06-18
CA2397614A1 (en) 2001-06-14
JP2012006971A (en) 2012-01-12
CA2397614C (en) 2009-11-10
EP1237561A2 (en) 2002-09-11
ATE260669T1 (en) 2004-03-15
AU781878C (en) 2001-06-18
USRE42755E1 (en) 2011-09-27
AU781878B2 (en) 2005-06-16
WO2001041776B1 (en) 2002-02-28
JP2003516357A (en) 2003-05-13
US6956144B2 (en) 2005-10-18
WO2001041776A2 (en) 2001-06-14
DE60008790T3 (en) 2009-12-10
DE60008790D1 (en) 2004-04-08
CN1409636A (en) 2003-04-09
EP1237561B1 (en) 2004-03-03

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