WO2002008414A1 - Novel nucleic acid probes and method of assaying nucleic acid by using the same - Google Patents

Novel nucleic acid probes and method of assaying nucleic acid by using the same Download PDF

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Publication number
WO2002008414A1
WO2002008414A1 PCT/IB2001/001147 IB0101147W WO0208414A1 WO 2002008414 A1 WO2002008414 A1 WO 2002008414A1 IB 0101147 W IB0101147 W IB 0101147W WO 0208414 A1 WO0208414 A1 WO 0208414A1
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
hybridization
same
assaying
fluorescent substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2001/001147
Other languages
English (en)
French (fr)
Inventor
Ryuichiro Kurane
Takahiro Kanagawa
Yoichi Kamagata
Masaki Torimura
Shinya Kurata
Kazutaka Yamada
Toyokazu Yokomaku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Advanced Industrial Science and Technology
Kankyo Engineering Co Ltd
Original Assignee
National Institute of Advanced Industrial Science and Technology
Kankyo Engineering Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2000193133A external-priority patent/JP3965872B2/ja
Application filed by National Institute of Advanced Industrial Science and Technology, Kankyo Engineering Co Ltd filed Critical National Institute of Advanced Industrial Science and Technology
Priority to DE60140804T priority Critical patent/DE60140804D1/de
Priority to EP01953279A priority patent/EP1295941B1/en
Priority to CA002383939A priority patent/CA2383939C/en
Publication of WO2002008414A1 publication Critical patent/WO2002008414A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PCT/IB2001/001147 2000-06-27 2001-06-27 Novel nucleic acid probes and method of assaying nucleic acid by using the same Ceased WO2002008414A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE60140804T DE60140804D1 (de) 2000-06-27 2001-06-27 Neue nukleinsäuresonden und verfahren zum testen von nukleinsäuren unter deren verwendung
EP01953279A EP1295941B1 (en) 2000-06-27 2001-06-27 Novel nucleic acid probes and method of assaying nucleic acid by using the same
CA002383939A CA2383939C (en) 2000-06-27 2001-06-27 Novel nucleic acid probes, method for determining nucleic acids by using the probes, and method for analyzing data obtained by the method

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2000-193133 2000-06-27
JP2000193133A JP3965872B2 (ja) 2000-06-27 2000-06-27 新規な定量的多型解析方法
JP2000-236115 2000-08-03
JP2000236115 2000-08-03
JP2000292483 2000-09-26
JP2000-292483 2000-09-26

Publications (1)

Publication Number Publication Date
WO2002008414A1 true WO2002008414A1 (en) 2002-01-31

Family

ID=27343862

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2001/001147 Ceased WO2002008414A1 (en) 2000-06-27 2001-06-27 Novel nucleic acid probes and method of assaying nucleic acid by using the same

Country Status (5)

Country Link
US (1) US7354707B2 (ja)
EP (1) EP1295941B1 (ja)
CA (1) CA2383939C (ja)
DE (1) DE60140804D1 (ja)
WO (1) WO2002008414A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1358346A2 (en) * 2000-03-07 2003-11-05 E.I. Dupont De Nemours And Company Real time quantitative pcr with intercalating dye for single and multiplex target dna
WO2003102179A1 (en) * 2002-05-31 2003-12-11 Kankyo Engineering Co., Ltd. Novel method of assyaing nucleic acid using labeled nucleotide
WO2010013317A1 (ja) * 2008-07-30 2010-02-04 株式会社Ｊ－Ｂｉｏ２１ 核酸プローブセットおよびその使用方法
US8346485B2 (en) 2008-11-25 2013-01-01 Quest Diagnostics Investments Incorporated Methods and apparatuses for estimating initial target nucleic acid concentration in a sample by modeling background signal and cycle-dependent amplification efficiency of a polymerase chain reaction

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CA2424614A1 (en) * 2001-03-27 2003-04-02 Kankyo Engineering Co., Ltd. Novel nucleic acid probe and novel method of assaying nucleic acids using the same
CN100439515C (zh) * 2003-03-03 2008-12-03 清华大学 一种核酸分析芯片实验室系统与应用
EP1601955B1 (en) 2003-03-07 2013-01-09 Luxcel Biosciences Limited An oxygen sensitive probe and method for measuring oxygen uptake
US7625723B2 (en) * 2003-04-16 2009-12-01 Arkray, Inc. Method of detecting or quantitatively determining mitochondrial DNA 3243 variation, and kit therefor
JP4454249B2 (ja) * 2003-04-18 2010-04-21 アークレイ株式会社 膵ラ氏島アミロイドタンパク質変異遺伝子の検出法ならびにそのための核酸プローブおよびキット
EP1625232B1 (en) * 2003-05-16 2013-09-04 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Internal control nucleic acid molecule for nucleic acid amplification systems
JP2007516426A (ja) * 2003-05-16 2007-06-21 ユニバーシティー オブ ロチェスター オリゴヌクレオチドの検出のための比色法および蛍光法
CN1280428C (zh) * 2003-05-19 2006-10-18 清华大学 一种基于微小颗粒的生物芯片系统及其应用
EP1716252A1 (en) * 2004-02-19 2006-11-02 University College Cork-National University of Ireland, Cork Detection of biologically active compounds
WO2006085964A2 (en) * 2004-06-30 2006-08-17 Applera Corporation Log-linear amplification
US20060110724A1 (en) 2004-11-19 2006-05-25 Burkhardt William Iii Quantitative real-time assay for noroviruses and enteroviruses with built in quality control standard
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US7794659B2 (en) 2005-03-10 2010-09-14 Gen-Probe Incorporated Signal measuring system having a movable signal measuring device
JP4789518B2 (ja) * 2005-06-30 2011-10-12 キヤノン株式会社 製造条件付きプローブ固定担体を用いた標的物質の検出方法ならびにそのための装置、キット及びシステム
US11001881B2 (en) 2006-08-24 2021-05-11 California Institute Of Technology Methods for detecting analytes
US8637436B2 (en) 2006-08-24 2014-01-28 California Institute Of Technology Integrated semiconductor bioarray
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US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
WO2008014485A2 (en) 2006-07-28 2008-01-31 California Institute Of Technology Multiplex q-pcr arrays
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
WO2008038259A1 (en) * 2006-09-28 2008-04-03 Stokes Bio Limited A qpcr analysis apparatus
EP2055789A4 (en) * 2006-11-30 2009-12-23 Arkray Inc PRIMER SET FOR THE REINFORCEMENT OF THE CYP2C19 GENE, REAGENT FOR THE REINFORCEMENT OF THE CYP2C19 GENE THEREFOR AND APPLICATION THEREOF
KR101110425B1 (ko) * 2006-11-30 2012-03-14 아크레이 가부시키가이샤 Ｎａｔ2 유전자 증폭용 프라이머 셋트, 그것을 포함하는 ｎａｔ2 유전자 증폭용 시약 및 그 용도
KR101179367B1 (ko) * 2007-01-10 2012-09-03 아크레이 가부시키가이샤 광학 검출 장치의 성능 확인 방법 및 그것에 이용하는 표준시약
US20100129796A1 (en) * 2008-11-24 2010-05-27 Micah Halpern Dye probe fluorescence resonance energy transfer genotyping
US9359639B2 (en) 2009-05-26 2016-06-07 Xiamen University Method for the detection of multiple single nucleotide variations or single nucleotide polymorphisms in a single tube
JP5575239B2 (ja) 2009-07-21 2014-08-20 ジェン−プローブ・インコーポレーテッド 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物
US8748095B2 (en) 2009-10-30 2014-06-10 Arkray, Inc. Probe for detecting polymorphism in EGFR gene and use of the probe
KR101982126B1 (ko) 2010-03-08 2019-05-27 몬산토 테크놀로지 엘엘씨 식물에서 유전자 조절을 위한 폴리뉴클레오타이드 분자
KR101386918B1 (ko) 2010-06-01 2014-04-18 아크레이 가부시키가이샤 Ｖｋｏｒｃ１ 유전자의 -1639번째의 염기의 다형 검출법, 및 그것을 위한 핵산 프로브 및 키트
JP5940771B2 (ja) 2010-07-12 2016-06-29 アークレイ株式会社 ａｂｌ遺伝子多型の検出用プローブおよびその用途
US9046507B2 (en) 2010-07-29 2015-06-02 Gen-Probe Incorporated Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure
EP2678664B1 (en) 2011-02-24 2019-08-07 Gen-Probe Incorporated Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector
KR20120103509A (ko) 2011-03-09 2012-09-19 아크레이 가부시키가이샤 Ｃｙｐ３ａ 유전자의 다형 검출용 프로브, 다형 검출 방법, 약효 평가 방법 및 다형 검출용 시약 키트
KR101660322B1 (ko) * 2011-04-28 2016-09-29 아크레이 가부시키가이샤 ＮＰＭ1 유전자의 ｅｘｏｎ12 변이의 검출용 프로브 및 그 용도
JP5757908B2 (ja) 2011-05-02 2015-08-05 アークレイ株式会社 多型検出用プローブ、多型検出方法、薬効評価方法、疾患予測方法及び多型検出用試薬キット
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
BR112014005975A8 (pt) * 2011-09-13 2017-09-12 Monsanto Technology Llc Método de controle de planta, método de redução de expressão de um gene pds em uma planta, cassete de expressão microbiana, método de fazer um polinucleotídeo, método de identificação de polinucleotídeos, e composições para controle de erva daninha
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
JP2013074888A (ja) 2011-09-15 2013-04-25 Arkray Inc ＩＬ２８Ｂ（ｒｓ８０９９９１７）とＩＴＰＡ（ｒｓ１１２７３５４）の変異を検出する方法
JP2013081450A (ja) * 2011-09-27 2013-05-09 Arkray Inc 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用試薬キット
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EP2698436A1 (en) * 2012-08-14 2014-02-19 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Colorectal cancer markers
JP5928906B2 (ja) 2013-08-27 2016-06-01 横河電機株式会社 核酸配列計測方法、核酸配列計測用デバイス、核酸配列計測用デバイスの製造方法および核酸配列計測装置
GB201319180D0 (en) * 2013-10-30 2013-12-11 Mast Group Ltd Nucleic acid probe
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US9708647B2 (en) 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1358346A2 (en) * 2000-03-07 2003-11-05 E.I. Dupont De Nemours And Company Real time quantitative pcr with intercalating dye for single and multiplex target dna
WO2003102179A1 (en) * 2002-05-31 2003-12-11 Kankyo Engineering Co., Ltd. Novel method of assyaing nucleic acid using labeled nucleotide
WO2010013317A1 (ja) * 2008-07-30 2010-02-04 株式会社Ｊ－Ｂｉｏ２１ 核酸プローブセットおよびその使用方法
US8346485B2 (en) 2008-11-25 2013-01-01 Quest Diagnostics Investments Incorporated Methods and apparatuses for estimating initial target nucleic acid concentration in a sample by modeling background signal and cycle-dependent amplification efficiency of a polymerase chain reaction

Also Published As

Publication number Publication date
EP1295941B1 (en) 2009-12-16
DE60140804D1 (de) 2010-01-28
EP1295941A1 (en) 2003-03-26
US7354707B2 (en) 2008-04-08
CA2383939C (en) 2009-12-01
CA2383939A1 (en) 2002-01-31
EP1295941A4 (en) 2004-06-16
US20020106653A1 (en) 2002-08-08

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