WO2003016170A1 - Systeme de contenant plus seringue - Google Patents

Systeme de contenant plus seringue Download PDF

Info

Publication number
WO2003016170A1
WO2003016170A1 PCT/KR2002/001543 KR0201543W WO03016170A1 WO 2003016170 A1 WO2003016170 A1 WO 2003016170A1 KR 0201543 W KR0201543 W KR 0201543W WO 03016170 A1 WO03016170 A1 WO 03016170A1
Authority
WO
WIPO (PCT)
Prior art keywords
container
syringe
rubber stopper
needle
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2002/001543
Other languages
English (en)
Inventor
Yeo Saeng Yoon
Byoung Hoon Park
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boo Yoon Tech Inc
Daewoong Co Ltd
Original Assignee
Boo Yoon Tech Inc
Daewoong Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boo Yoon Tech Inc, Daewoong Co Ltd filed Critical Boo Yoon Tech Inc
Publication of WO2003016170A1 publication Critical patent/WO2003016170A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2065—Connecting means having aligning and guiding means

Definitions

  • the present invention relates to a container plus syringe system, and more particularly, to a container plus syringe system capable of separately charging and storing two different medicaments in a container and a syringe, which secures safety and stability of medicaments, prevents medicaments from contamination by microorganisms or environmental pathogens, facilitates its use to mix medicaments, and eventually, optimizes the efficiency and preservation of health.
  • medicaments which are stored separately and mixed or dissolved in fluid either prior to or during administration, are in the form of powers, solutions, lyophilized cakes, or tablets.
  • these medicaments are stored separately and mixed either prior to or during administration, there is a possibility that the contents may be contaminated by microorganisms or environmental pathogens or require a high manufacturing cost, thus being insufficient for practical uses.
  • a clinician or a technician may be able to reduce the likelihood of contamination but the risk still exists. Then, it may be much harder for patients or the old and the weak to use such products and avoid the contamination.
  • pre-filled syringes having two separate storages requires high cost of manufacture and maintenance, is limited only to an intravascular administration, and is difficult to be properly packaged and used because a container and a syringe are prepared separately.
  • a container plus syringe system the use of which comprising steps of pressing a needle part mounted between a needle case and a syringe with ease, mixing two medicaments by injecting a medicament in a syringe into a medicament in a container, removing the needle case and the syringe, and holding the container containing mixed medicaments safely with a support as well as gripping the same conveniently with a finger grip.
  • the container plus syringe system of the present invention comprises: a container containing one medicament wherein one side is clogged by a content discharging member and the other side by a rubber stopper; a syringe containing the other medicament wherein one side is sealed by a rubber stopper and the other by a content pressurizing member; a needle part having a double-edged needle; and a needle case connecting the container and the syringe, where the medicament in the syringe is injected by pressing the content pressurizing member into the medicament in the container to mix employing the needle case.
  • the container containing the mixed medicaments is stored by holding the rubber stopper thereof safely with a support.
  • the content discharging member of the container may be a spray nozzle, a seal with brush, or a dropper, or a special seal with ball type or sponge type.
  • the syringe comprises: a glass tube containing a medicament; a plunger rubber at the front end to charge the medicament; a plunger rod combined with the plunger rubber; a rubber stopper to seal the front end of the glass tube; an aluminum cap to cover the rubber stopper except the center thereof; and a finger grip connected to the terminal end of the glass tube and supporting fingers when the plunger rod is pressed.
  • the plunger rubber is mounted on a screw of a plunger rod.
  • the rubber stopper includes 3 protruded support hump sides at equal intervals at the site inserted into the front end of the glass tube.
  • the needle case comprises two portions: a portion where the needle case is connected with the container, and a portion with a certain length as a body of the needle where the needle case is connected with the syringe.
  • the inner diameter portion of the needle case includes a first internal catching projection to set up the first insertion position of the rubber stopper of the syringe at the terminal end, and two axially-spaced, generally parallel, second internal catching projections to set up the first setting position of the needle part at a middle portion of the needle case.
  • the needle part comprises a cylindrical body to be positioned at the second internal catching projections of the inner diameter portion of the needle case; and a needle with a certain length inserted piercing through the cylindrical body wherein one side is toward the rubber stopper of the container and the other is toward the rubber stopper of the syringe.
  • the support 26 to stand the container on end comprises a tube holding portion having internal round jaw and certain height at the upper side to insert the rubber stopper, and a flat portion having wider area at the bottom side.
  • Fig. 1 is a perspective vie'w showing the entire constitution of the container plus syringe system according to the present invention
  • Fig. 2 is a cross-sectional perspective view showing the assembly of the container plus syringe system according to the present invention
  • Fig. 3 is a cross-sectional view of the container plus syringe system according to the present invention wherein a medicament in the container and a medicament in the syringe are confined to its respective place ready to be mixed;
  • Fig. 4 is a cross-sectional view showing the combined state among the container, needle part and syringe of the container plus syringe system according to the present invention
  • Fig. 5 is a cross-sectional view after mixing a medicament in the container and a medicament in the syringe of the container plus syringe system according to the present invention
  • Fig. 6 is a partial sectional view showing the container containing the mixed medicaments of the container plus syringe system according to the present invention
  • Fig. 7 is a cross-sectional perspective view showing the needle part of the container plus syringe system according to the present invention.
  • Fig. 8 is a perspective view showing the rubber stopper of the syringe of the container plus syringe system according to the present invention.
  • Figs. 9a-9d are perspective views showing the rubber stopper of the container of the container plus syringe system according to the present invention.
  • Fig. 10 is a cross-sectional perspective view showing the combined state between the syringe body and the finger grip of the container plus syringe system according to the present invention.
  • Fig. 1 is a perspective view showing the entire constitution of the container plus syringe system according to the present invention.
  • a needle case 12 interconnects a container 10, a syringe 11 and a needle part 24 and serves as a place where a medicament filled in a container 10 and a medicament filled in a syringe 11 are admixed in the container 10.
  • the container 10 is sealed one side with a content discharging member such as a spray nozzle, a seal with brush, a dropper, and a special seal with ball or sponge, and the other side with a rubber stopper 13a and an aluminum cap 14a to store the medicament safely.
  • a content discharging member such as a spray nozzle, a seal with brush, a dropper, and a special seal with ball or sponge
  • the aluminum cap 14a covers the rubber stopper 13a except the center thereof to rupture the rubber stopper with a needle.
  • the spray nozzle 16 is applied for the content discharging member and the reference number 17 represents a clear cap capable of closing the spray nozzle 16.
  • the syringe 11 comprises a glass tube 18 which is a main body of the syringe; a plunger rubber 19 at the front end to administer the medicament; a plunger rod 20 where users directly provide pressure; and a finger grip 21 connected to the terminal end of the glass tube 18 and supporting fingers when the plunger rod is pressed.
  • the glass tube 18 wherein one side is clogged by the plunger rubber 19, the other side is sealed by a rubber stopper 13b and aluminum cap 14b to prevent the discharge of contents in the glass tube 18 unless the plunger rod 20 is operated.
  • the needle 15 may rupture the center of the aluminum cap 14b to release the contained composition in the glass tube and the plunger rubber 19 is mounted on a screw of the plunger rod 20 to hold firmly each other while the operation of the plunger rod 20.
  • the finger grip 21 has a polygonal shape which is close to a circle, preferably a hexagonal shape, to place fingers freely during the operation of the plunger rod 20.
  • the needle case 12 having a cylindrical body comprises an outer diameter portion 22 to insert the rubber stopper 13a of the container and an inner diameter portion 23 having a certain length as a body of the needle.
  • the needle part 24 holding a needle 15 is installed to release the medicament in the syringe 11 into the medicament in the container inside of the inner diameter portion 23.
  • Fig. 2 is a sectional perspective view showing the combined state of the container plus syringe system according to the present invention.
  • the rubber stopper 13a of the container 10 and the aluminum cap 14a are attached to the outer diameter portion 22 of the needle case 12 and the rubber stopper 13b of the syringe 11 and the aluminum cap 14b are attached to the inner diameter portion 23. Further, the needle part 24 is installed at the middle portion of the inner diameter portion 23 of the needle case 12.
  • the rubber stopper 13a of the container 10 and the aluminum cap 14a are inserted into the third internal catching projection 25c formed in the outer diameter portion 22, while the rubber stopper 13b of the syringe 11 and the aluminum cap 14b are positioned at the first internal catching projection 25a of the inner diameter portion 23 and the needle part 24 is positioned at the two axially-spaced, generally parallel, second internal catching projection 25b formed in the middle of the inner diameter portion 23.
  • each medicament contained in the container and the syringe may be mixed.
  • Fig. 3 is a sectional view prior to mixing a medicament in the container and a medicament in the syringe of the container plus syringe system according to the present invention.
  • the container 10 and the syringe 11 having the needle case 12 inbetween are firmly positioned by each catching projections, 25a, 25b, and 25c.
  • Fig. 4 is a sectional view showing the combined state among the container, needle part and syringe of the container plus syringe system according to the present invention.
  • Fig. 5 is a sectional view after mixing a medicament in the container and a medicament in the syringe of the container plus syringe system according to the present invention.
  • FIG. 6 is a partial sectional view showing the container containing the mixed medicaments of the container plus syringe system according to the present invention.
  • the container containing the mixed contents may be stored by sealing the rubber stopper which is held by the aluminum cap and held safely with the support 26.
  • the support 26 comprises a tube holding portion having internal round jaw
  • Fig. 7 is a cross-sectional perspective view showing the needle part of the container plus syringe system according to the present invention.
  • the outer round of the cylindrical body of the needle case 24 is contacted with the inner round of the inner diameter portion 23 of the needle case 12, and the needle 15 piercing through the center of the body is held by a couple of projections 28 at the center of the body.
  • Fig. 8 is a perspective view showing the rubber stopper of the syringe of the container plus syringe system according to the present invention
  • the rubber stopper 13b includes three support humps 29a at 120° intervals at the site inserted into the glass tube 18.
  • Figs. 9a-9d are perspective views showing the rubber stopper of the container of the container plus syringe system according to the present invention.
  • FIG. 10 is a sectional perspective view showing the combined state between the syringe body and the finger grip of the container plus syringe system according to the present invention.
  • the finger grip 21 is slidably mounted onto the outer diameter of the glass tube 18 by a base which may also include a ring 30 to prevent movement of the finger grip 21 too far down the glass tube 18.
  • the container plus syringe system of the present invention provides optimal stability and safety preventing contamination by microorganisms or environmental pathogens, facilitates its use relating to mixing contents to be delivered, and simplifies the process to use after mixing contents, thus eventually, exhibiting improvement in preservation of health and effectiveness of treatments.

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La présente invention concerne un système de contenant plus seringue qui est facile à prendre en main lorsqu'on l'utilise et qui renferme une composition pharmaceutique contenue dans une seringue qu'on introduit facilement dans un contenant lorsqu'on pousse la partie d'aiguille dans le logement d'aiguille, ceci permettant de mélanger la composition pharmaceutique contenue dans une seringue et la composition pharmaceutique contenue dans ledit contenant, le logement d'aiguille et la partie seringue étant ensuite enlevés et ledit contenant renfermant ledit mélange étant stocké en position verticale.
PCT/KR2002/001543 2001-08-13 2002-08-13 Systeme de contenant plus seringue Ceased WO2003016170A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR2001-48647 2001-08-13
KR10-2001-0048647A KR100431704B1 (ko) 2001-08-13 2001-08-13 용기 플러스 시린지 시스템

Publications (1)

Publication Number Publication Date
WO2003016170A1 true WO2003016170A1 (fr) 2003-02-27

Family

ID=19713143

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2002/001543 Ceased WO2003016170A1 (fr) 2001-08-13 2002-08-13 Systeme de contenant plus seringue

Country Status (2)

Country Link
KR (1) KR100431704B1 (fr)
WO (1) WO2003016170A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017057659A1 (fr) * 2015-09-30 2017-04-06 科研製薬株式会社 Dispositif de seringue pour amener deux types de substances en communication et procédé associé
CN113776726A (zh) * 2021-08-17 2021-12-10 宁波旭日温压仪表有限公司 一种测压接头及测压系统

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7174953B2 (ja) * 2019-03-28 2022-11-18 大成化工株式会社 シリンジ用の調製補助具

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171219A (en) * 1989-06-08 1992-12-15 Sumitomo Pharmaceuticals Co., Ltd. Pharmaceutical preparation administrator
US5588745A (en) * 1994-09-02 1996-12-31 Howmedica Methods and apparatus for mixing bone cement components using an evacuated mixing chamber
US6149623A (en) * 1996-01-11 2000-11-21 Duoject Medical Systems Inc. Delivery system for pharmaceuticals packed in pharmaceutical vials

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0752060Y2 (ja) * 1990-03-05 1995-11-29 阪神化成工業株式会社 二物体の分離収納容器
JPH0796978A (ja) * 1993-09-21 1995-04-11 Kanae:Kk 分離収納及び混合使用兼用容器
JP3456019B2 (ja) * 1994-06-17 2003-10-14 ニプロ株式会社 液体導入針およびそれを用いた乾燥製剤溶解補助具
DE19513666C1 (de) * 1995-04-11 1996-11-28 Behringwerke Ag Vorrichtung zum Zusammenführen einer ersten flüssigen und einer zweiten festen oder flüssigen Komponente mittels Unterdruck unter sterilen Bedingungen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171219A (en) * 1989-06-08 1992-12-15 Sumitomo Pharmaceuticals Co., Ltd. Pharmaceutical preparation administrator
US5588745A (en) * 1994-09-02 1996-12-31 Howmedica Methods and apparatus for mixing bone cement components using an evacuated mixing chamber
US6149623A (en) * 1996-01-11 2000-11-21 Duoject Medical Systems Inc. Delivery system for pharmaceuticals packed in pharmaceutical vials

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017057659A1 (fr) * 2015-09-30 2017-04-06 科研製薬株式会社 Dispositif de seringue pour amener deux types de substances en communication et procédé associé
CN108135777A (zh) * 2015-09-30 2018-06-08 科研制药株式会社 用于连通两种物质的注射器装置及其方法
JPWO2017057659A1 (ja) * 2015-09-30 2018-07-26 科研製薬株式会社 ２種類の物質を連通するためのシリンジ装置及びその方法
US10646402B2 (en) 2015-09-30 2020-05-12 Kaken Pharmaceutical Co., Ltd. Syringe device for communicating two types of substances to each other and method thereof
RU2726477C1 (ru) * 2015-09-30 2020-07-14 Какен Фармасьютикал Ко., Лтд. Шприцевое устройство для взаимодействия двух типов веществ друг с другом и способ для этого
CN108135777B (zh) * 2015-09-30 2022-02-18 科研制药株式会社 用于连通两种物质的注射器装置及其方法
CN113776726A (zh) * 2021-08-17 2021-12-10 宁波旭日温压仪表有限公司 一种测压接头及测压系统
CN113776726B (zh) * 2021-08-17 2023-11-24 宁波旭日温压仪表有限公司 一种测压接头及测压系统

Also Published As

Publication number Publication date
KR20030014785A (ko) 2003-02-20
KR100431704B1 (ko) 2004-05-17

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