WO2003029208A3 - Verfahren zur herstellung von vanillylamin hydrochlorid - Google Patents

Verfahren zur herstellung von vanillylamin hydrochlorid Download PDF

Info

Publication number
WO2003029208A3
WO2003029208A3 PCT/EP2002/010803 EP0210803W WO03029208A3 WO 2003029208 A3 WO2003029208 A3 WO 2003029208A3 EP 0210803 W EP0210803 W EP 0210803W WO 03029208 A3 WO03029208 A3 WO 03029208A3
Authority
WO
WIPO (PCT)
Prior art keywords
producing
vanillylamine
organic
salts
produced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/010803
Other languages
English (en)
French (fr)
Other versions
WO2003029208A2 (de
Inventor
Oliver Meyer
Ingo Heddesheimer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH and Co KG, Boehringer Ingelheim Pharmaceuticals Inc filed Critical Boehringer Ingelheim Pharma GmbH and Co KG
Priority to DE50205226T priority Critical patent/DE50205226D1/de
Priority to AU2002333879A priority patent/AU2002333879A1/en
Priority to EP02800124A priority patent/EP1432675B1/de
Priority to JP2003532458A priority patent/JP4272521B2/ja
Priority to CA2461574A priority patent/CA2461574C/en
Priority to AT02800124T priority patent/ATE312071T1/de
Publication of WO2003029208A2 publication Critical patent/WO2003029208A2/de
Publication of WO2003029208A3 publication Critical patent/WO2003029208A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Verfahren zur Herstellung von Vanillylamin oder eines seiner Salze durch a) Umsetzung von Vanillin mit Hydroxylamin oder dessen Salzen in Gegenwart eines organischen Salzes, welches gegebenenfalls in situ erzeugt werden kann, und b) anschließende Hydrierung des entstandenen Vanillyloxims mit Wasserstoff in Gegenwart eines geeigneten Katalysators und einer organischen und/oder anorganischen Säure, dadurch gekennzeichnet, dass Schritt a) in einer anorganischen oder organischen Säure als Verdünnungsmittel durchgeführt wird.
PCT/EP2002/010803 2001-09-28 2002-09-26 Verfahren zur herstellung von vanillylamin hydrochlorid Ceased WO2003029208A2 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE50205226T DE50205226D1 (de) 2001-09-28 2002-09-26 Verfahren zur herstellung von vanillylamin hydrochlorid
AU2002333879A AU2002333879A1 (en) 2001-09-28 2002-09-26 Method for producing vanillylamine hydrochloride
EP02800124A EP1432675B1 (de) 2001-09-28 2002-09-26 Verfahren zur herstellung von vanillylamin hydrochlorid
JP2003532458A JP4272521B2 (ja) 2001-09-28 2002-09-26 バニリル塩酸塩の調製方法
CA2461574A CA2461574C (en) 2001-09-28 2002-09-26 Process for preparing vanillylamine hyrochloride
AT02800124T ATE312071T1 (de) 2001-09-28 2002-09-26 Verfahren zur herstellung von vanillylamin hydrochlorid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10147958A DE10147958A1 (de) 2001-09-28 2001-09-28 Verfahren zur Herstellung von Yanillylamin Hydrochlorid
DE10147958.1 2001-09-28

Publications (2)

Publication Number Publication Date
WO2003029208A2 WO2003029208A2 (de) 2003-04-10
WO2003029208A3 true WO2003029208A3 (de) 2003-09-12

Family

ID=7700689

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/010803 Ceased WO2003029208A2 (de) 2001-09-28 2002-09-26 Verfahren zur herstellung von vanillylamin hydrochlorid

Country Status (8)

Country Link
EP (1) EP1432675B1 (de)
JP (1) JP4272521B2 (de)
AT (1) ATE312071T1 (de)
AU (1) AU2002333879A1 (de)
CA (1) CA2461574C (de)
DE (2) DE10147958A1 (de)
ES (1) ES2253581T3 (de)
WO (1) WO2003029208A2 (de)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE760746C (de) * 1941-02-21 1953-05-18 Boehringer & Soehne Gmbh Verfahren zur Herstellung von primaeren Aminen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2397387A1 (fr) * 1976-04-27 1979-02-09 Serobiologiques Lab Sa 4,4'-bis-formyl-polyhalo-diphenoxyalcanes, procede de preparation et application a la synthese de 4,4'-dicyano-polyhalo-diphenoxyalcanes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE760746C (de) * 1941-02-21 1953-05-18 Boehringer & Soehne Gmbh Verfahren zur Herstellung von primaeren Aminen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ANU R. BAIPAI ET AL: "An efficient one-pot synthesis of armomatic nitriles from aldehydes using Fe modified K10", SYNTHETIC COMMUNICATION, vol. 30, no. 15, 2000, pages 2785 - 2791, XP009003066 *

Also Published As

Publication number Publication date
JP4272521B2 (ja) 2009-06-03
AU2002333879A1 (en) 2003-04-14
CA2461574A1 (en) 2003-04-10
JP2005527478A (ja) 2005-09-15
DE50205226D1 (de) 2006-01-12
ES2253581T3 (es) 2006-06-01
WO2003029208A2 (de) 2003-04-10
EP1432675B1 (de) 2005-12-07
CA2461574C (en) 2011-01-11
ATE312071T1 (de) 2005-12-15
EP1432675A2 (de) 2004-06-30
DE10147958A1 (de) 2003-04-30

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