BRPI0411921A - processo para preparar intermediários úteis para preparar determinadas hidroxilaminas de n-formila antibacterianas - Google Patents

processo para preparar intermediários úteis para preparar determinadas hidroxilaminas de n-formila antibacterianas

Info

Publication number
BRPI0411921A
BRPI0411921A BRPI0411921-5A BRPI0411921A BRPI0411921A BR PI0411921 A BRPI0411921 A BR PI0411921A BR PI0411921 A BRPI0411921 A BR PI0411921A BR PI0411921 A BRPI0411921 A BR PI0411921A
Authority
BR
Brazil
Prior art keywords
preparing
certain antibacterial
intermediates useful
formyl
hydroxylamines
Prior art date
Application number
BRPI0411921-5A
Other languages
English (en)
Inventor
Joel Slade
James Anthony Vivelo
Guang-Pei Chen
Joginder Singh Bajwa
David John Parker
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0411921A publication Critical patent/BRPI0411921A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

"PROCESSO PARA PREPARAR INTERMEDIáRIOS úTEIS PARA PREPARAR DETERMINADAS HIDROXILAMINAS DE NFORMILA ANTIBACTERIANAS". A presente invenção refere-se a um processo para preparar intermediários que são úteis para preparar determinados compostos de hidroxilamina de N-formila antibacterianos, que são inibidores de deformilase de peptídeos.
BRPI0411921-5A 2003-06-26 2004-06-25 processo para preparar intermediários úteis para preparar determinadas hidroxilaminas de n-formila antibacterianas BRPI0411921A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48268603P 2003-06-26 2003-06-26
PCT/EP2004/006915 WO2005000835A1 (en) 2003-06-26 2004-06-25 Process for preparing intermediates useful to prepare certain antibacterial n-formyl hydroxylamines

Publications (1)

Publication Number Publication Date
BRPI0411921A true BRPI0411921A (pt) 2006-08-15

Family

ID=33552002

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0411921-5A BRPI0411921A (pt) 2003-06-26 2004-06-25 processo para preparar intermediários úteis para preparar determinadas hidroxilaminas de n-formila antibacterianas

Country Status (11)

Country Link
US (2) US20070060753A1 (pt)
EP (1) EP1641778A1 (pt)
JP (1) JP2009513485A (pt)
KR (1) KR20060026445A (pt)
CN (1) CN100410251C (pt)
AU (2) AU2004251876A1 (pt)
BR (1) BRPI0411921A (pt)
CA (1) CA2530142A1 (pt)
IL (1) IL172681A0 (pt)
MX (1) MXPA05014217A (pt)
WO (1) WO2005000835A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2283589T3 (es) 2001-06-15 2007-11-01 Vicuron Pharmaceuticals, Inc. Compuestos biciclicos de pirrolidina.
US7589216B2 (en) 2002-09-19 2009-09-15 Novartis Ag Process for preparing N-hydroxyformamido-propyl pyrrolidin compounds and intermediates
JP2006519786A (ja) 2003-02-21 2006-08-31 ノバルティス アクチエンゲゼルシャフト Ｎ−ホルミルヒドロキシルアミン化合物を得るための中間体作成に関する化学的方法
GT200600196A (es) * 2005-05-23 2007-01-15 Compuestos n-formil de hidroxilamina
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria
CN112538058B (zh) * 2020-12-26 2022-05-27 温州大学新材料与产业技术研究院 含恶唑环砜类化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613676A (en) * 1983-11-23 1986-09-23 Ciba-Geigy Corporation Substituted 5-amino-4-hydroxyvaleryl derivatives
DE69701298T2 (de) * 1996-04-15 2000-10-05 Takeda Chemical Industries, Ltd. Hydroxypyridin-Derivate, ihre Herstellung und ihre pharmazeutische Verwendung
GB2349884A (en) * 1998-02-07 2000-11-15 British Biotech Pharm Antibacterial agents
GB9907055D0 (en) * 1999-03-29 1999-05-19 British Biotech Pharm Antibacterial agents
AR036053A1 (es) * 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas

Also Published As

Publication number Publication date
IL172681A0 (en) 2006-04-10
JP2009513485A (ja) 2009-04-02
KR20060026445A (ko) 2006-03-23
AU2009201025A1 (en) 2009-04-02
EP1641778A1 (en) 2006-04-05
CA2530142A1 (en) 2005-01-06
US20090118515A1 (en) 2009-05-07
AU2004251876A1 (en) 2005-01-06
CN100410251C (zh) 2008-08-13
MXPA05014217A (es) 2006-03-09
US20070060753A1 (en) 2007-03-15
CN1829710A (zh) 2006-09-06
WO2005000835A1 (en) 2005-01-06

Similar Documents

Publication Publication Date Title
BRPI0411268C8 (pt) Processo para a preparação de compostos 3-aril butil-amina substituído
BRPI0615705A2 (pt) processo para preparar um composto, e, composto
BRPI0518459A2 (pt) composto ou um sal farmaceuticamente aceitÁvel do mesmo, composiÇço farmacÊutica, uso de um composto, e, processo para preparar o composto ou um sal farmaceuticamente aceitÁvel do mesmo
CR9866A (es) Novedosos derivados de 1-aza-bicicloalquilo para el tratamiento de trastornos psicoticos y neurodegenerativos
BR0305258A (pt) Inibidores de polimerase de ns5b de hcv
BR0308158B1 (pt) processo para o melhoramento de correntes brutas de hidrocarbonetos.
BRPI0500480A (pt) processo para a sìntese de (1s)-4,5-dimetóxi- 1-(metilaminometil)-benzociclobutano e sais de adição deste, e aplicação na sìntese de ivabradina e sais de adição desta com um ácido farmaceuticamente aceitável
DE602004024798D1 (de) Herstellung von quetiapin
UA102817C2 (ru) Способ синтеза агомелатина
BRPI0417992A (pt) método para purificar fsh
UA102220C2 (ru) Способ синтеза агомелатина
BR0301667B1 (pt) processo para a preparaÇço de polÍmeros em emulsço com pureza elevada.
HRP20080057T3 (en) 9,10-alpha,alpha-oh-taxane analogs and methods for production thereof
BRPI0715051A2 (pt) Processo e intermediários para a síntese de derivados de 2-(quinolin-5il)-4,5 dissubstituído-azol
BRPI0411921A (pt) processo para preparar intermediários úteis para preparar determinadas hidroxilaminas de n-formila antibacterianas
EA200500202A1 (ru) Новый способ синтеза (7-метокси-3,4-дигидро-1-нафталинил)ацетонитрила и его применение при синтезе агомелатина
BRPI0720835A2 (pt) processo para preparação de 3,5-di-omicron-acil-2-fluoro-2-c-metil-d-ribono-gama-lactona
BRPI0411652A (pt) processo para a preparação de derivados de espirobenzoazepina substituìdos não-peptìdicos
BRPI0412721A (pt) processo para preparar bromidrato de eletriptano alfa-polimórfico
BRPI0507979A (pt) processo para preparação de um composto
BRPI0408104A (pt) processo para a produção de tibolona
BR0314592A (pt) Processo para preparação de intermediários
BRPI0408453A (pt) composto, composição farmacêutica, uso de um composto, e, método para o tratamento de um distúrbio afetivo
BR0209842A (pt) Processo para a preparação de imipenem
BR0315508A (pt) Processo para preparação de compostos de pirazol

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 7A. ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE A 7A ANUIDADE.