WO2003043565A3 - Methodes de diagnostic et de traitement de maladies associees a l'expression modifiee de nrf2 - Google Patents
Methodes de diagnostic et de traitement de maladies associees a l'expression modifiee de nrf2 Download PDFInfo
- Publication number
- WO2003043565A3 WO2003043565A3 PCT/IB2002/005830 IB0205830W WO03043565A3 WO 2003043565 A3 WO2003043565 A3 WO 2003043565A3 IB 0205830 W IB0205830 W IB 0205830W WO 03043565 A3 WO03043565 A3 WO 03043565A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- diagnosis
- treatment
- nrf2
- methods
- diseases associated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2002364889A AU2002364889A1 (en) | 2001-09-24 | 2002-09-24 | Methods for diagnosis and treatment of diseases associated with altered expression of nrf2 |
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/963,131 | 2001-09-24 | ||
| US09/962,916 | 2001-09-24 | ||
| US09/962,916 US20030077590A1 (en) | 2000-09-22 | 2001-09-24 | Methods for diagnosis and treatment of diseases associated with altered expression of neurogranin |
| US09/962,854 | 2001-09-24 | ||
| US09/962,855 | 2001-09-24 | ||
| US09/962,854 US20030044803A1 (en) | 2000-09-22 | 2001-09-24 | Methods for diagnosis and treatment of diseases associated with altered expression of JAK1 |
| US09/963,131 US20030224460A1 (en) | 2000-09-22 | 2001-09-24 | Novel compositions and methods for lymphoma and leukemia |
| US09/962,929 | 2001-09-24 | ||
| US09/962,929 US20020115058A1 (en) | 2000-09-22 | 2001-09-24 | Methods for diagnosis and treatment of diseases associated with altered expression of Pik3r1 |
| US09/962,855 US20020164576A1 (en) | 2000-09-22 | 2001-09-24 | Methods for diagnosis and treatment of diseases associated with altered expression of Nrf2 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2003043565A2 WO2003043565A2 (fr) | 2003-05-30 |
| WO2003043565A3 true WO2003043565A3 (fr) | 2003-11-13 |
Family
ID=27542309
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IB2002/004197 Ceased WO2003027295A2 (fr) | 2001-09-24 | 2002-09-24 | Procedes de diagnostic et de traitement de maladies associees a l'expression alteree de la jak1 |
| PCT/IB2002/004134 Ceased WO2003027276A2 (fr) | 2001-09-24 | 2002-09-24 | Nouvelles compositions et procedes relatifs aux lymphomes et aux leucemies |
| PCT/IB2002/005830 Ceased WO2003043565A2 (fr) | 2001-09-24 | 2002-09-24 | Methodes de diagnostic et de traitement de maladies associees a l'expression modifiee de nrf2 |
| PCT/IB2002/004158 Ceased WO2003027321A2 (fr) | 2001-09-24 | 2002-09-24 | Methodes de diagnostic et de traitement de maladies associees a une expression alteree de neurogranine |
| PCT/IB2002/004123 Ceased WO2003027320A2 (fr) | 2001-09-24 | 2002-09-24 | Methodes de diagnostic et de traitement de maladies associees a l'expression modifiee de pik3r1 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IB2002/004197 Ceased WO2003027295A2 (fr) | 2001-09-24 | 2002-09-24 | Procedes de diagnostic et de traitement de maladies associees a l'expression alteree de la jak1 |
| PCT/IB2002/004134 Ceased WO2003027276A2 (fr) | 2001-09-24 | 2002-09-24 | Nouvelles compositions et procedes relatifs aux lymphomes et aux leucemies |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IB2002/004158 Ceased WO2003027321A2 (fr) | 2001-09-24 | 2002-09-24 | Methodes de diagnostic et de traitement de maladies associees a une expression alteree de neurogranine |
| PCT/IB2002/004123 Ceased WO2003027320A2 (fr) | 2001-09-24 | 2002-09-24 | Methodes de diagnostic et de traitement de maladies associees a l'expression modifiee de pik3r1 |
Country Status (2)
| Country | Link |
|---|---|
| AU (4) | AU2002330713A1 (fr) |
| WO (5) | WO2003027295A2 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006265113A1 (en) * | 2005-07-01 | 2007-01-11 | The Johns Hopkins University | Compositions and methods for the treatment or prevention of disorders relating to oxidative stress |
| SG169981A1 (en) * | 2006-02-14 | 2011-04-29 | Harvard College | Mitotic progression genes and methods of modulating mitosis |
| US12577278B2 (en) * | 2019-06-07 | 2026-03-17 | Emory University | KRAS G12V mutant binds to JAK1, inhibitors, pharmaceutical compositions, and methods related thereto |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999041985A1 (fr) * | 1998-02-23 | 1999-08-26 | Quark Biotech, Inc. | Secretion de facteurs inhibiteurs de croissance dependant de p53 |
| WO1999065928A2 (fr) * | 1998-06-19 | 1999-12-23 | Genzyme Corporation | Population de polynucleotides isoles de tissus mammaires tumoraux metastatiques ou non metastatiques |
| WO2001057189A2 (fr) * | 2000-02-07 | 2001-08-09 | Quark Biotech, Inc. | Genes de la voie fas |
| WO2001096390A2 (fr) * | 2000-06-09 | 2001-12-20 | Corixa Corporation | Compositions et procedes pour la therapie et le diagnostic du cancer du colon |
| WO2002020849A2 (fr) * | 2000-09-08 | 2002-03-14 | New York University | Marqueurs de gene utiles pour detecter des lesions de la peau dues au rayonnement ultraviolet |
| WO2002020846A2 (fr) * | 2000-09-08 | 2002-03-14 | New York University | Methodes de criblage pour identifier des composes modulant une reponse d'une cellule a l'exposition a un rayonnement ultraviolet |
| WO2002022884A2 (fr) * | 2000-09-12 | 2002-03-21 | Transgenetics Incorporated | Organisation en micro-reseaux de genes cibles de facteur de transcription |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ237669A (en) * | 1990-04-13 | 1992-08-26 | Res Dev Foundation | T-cell proteins expressed in t-cell development and their preparation |
| US5821069A (en) * | 1993-06-30 | 1998-10-13 | Ludwig Institute For Cancer Research | Method for determining tyrosine kinase in a sample |
| US6300058B1 (en) * | 1992-01-29 | 2001-10-09 | Hitachi Chemical Research Center, Inc. | Method for measuring messenger RNA |
| WO1997003358A1 (fr) * | 1995-07-07 | 1997-01-30 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Procede pour identifier des inhibiteurs de la voie de transduction de signaux jak-stat |
| WO1998016557A1 (fr) * | 1996-10-11 | 1998-04-23 | The General Hospital Corporation | Dosages pour recepteurs lies a la proteine g |
| WO1998020126A1 (fr) * | 1996-11-01 | 1998-05-14 | Onyx Pharmaceuticals, Inc. | Sequences nucleotidiques codant des proteines associees de phosphatidylinositol-3 kinase et leurs utilisations |
| US5994076A (en) * | 1997-05-21 | 1999-11-30 | Clontech Laboratories, Inc. | Methods of assaying differential expression |
| JP2002504812A (ja) * | 1997-05-21 | 2002-02-12 | クローンテック ラボラトリーズ,インコーポレイテッド | 核酸アレイ |
| JP2002519000A (ja) * | 1998-01-28 | 2002-07-02 | カイロン コーポレイション | ヒト遺伝子および遺伝子発現産物ii |
| ATE269295T1 (de) * | 1998-04-17 | 2004-07-15 | Parker Hughes Inst | Btk inhibitoren und verfahren zur identifizierung und verwendung |
| DE19817947A1 (de) * | 1998-04-17 | 1999-10-28 | Metagen Gesellschaft Fuer Genomforschung Mbh | Menschliche Nukleinsäuresequenzen aus Myometrium-Tumorgewebe |
| US6100090A (en) * | 1999-06-25 | 2000-08-08 | Isis Pharmaceuticals Inc. | Antisense inhibition of PI3K p85 expression |
| EP1140973A4 (fr) * | 1998-12-22 | 2002-10-30 | Myriad Genetics Inc | Interactions proteine-proteine dans les troubles neurodegeneratifs |
| US6110664A (en) * | 1999-06-25 | 2000-08-29 | Isis Pharmaceuticals Inc. | Antisense inhibition of G-alpha-S1 expression |
| GB9917165D0 (en) * | 1999-07-22 | 1999-09-22 | Knoll Ag | Polypeptides polynuclcotides and uses thereof |
| AU779908B2 (en) * | 1999-09-10 | 2005-02-17 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| WO2001030973A2 (fr) * | 1999-10-25 | 2001-05-03 | Princeton University | Sequences genetiques associees a la proliferation et aux pathologies des cellules neuronales |
| WO2001034633A2 (fr) * | 1999-11-12 | 2001-05-17 | Fred Hutchinson Cancer Research Center | Methodes de traitement de la forme humaine de la maladie de huntington et methodes de criblage d'agents actifs |
| CA2395607A1 (fr) * | 2000-01-07 | 2001-07-19 | Curagen Corporation | Acides nucleiques renfermant des polymorphismes de nucleotide simple et procede d'utilisation associe |
| GEP20084317B (en) * | 2000-04-25 | 2008-02-25 | Icos Corp | Inhibitors of human phosphatidyl-inositol 3-kinase delta |
| CN1173975C (zh) * | 2000-04-27 | 2004-11-03 | 山之内制药株式会社 | 咪唑并吡啶衍生物 |
| WO2002022882A2 (fr) * | 2000-09-13 | 2002-03-21 | Archemix Corporation | Biocapteur d'acide nucleique active par une cible et ses procedes d'utilisation |
| WO2002040637A2 (fr) * | 2000-11-20 | 2002-05-23 | Isis Pharmaceuticals, Inc. | Modulation antisens de l'expression de pi3k p85 |
| WO2002059367A2 (fr) * | 2000-11-30 | 2002-08-01 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Jeu de microechantillons de diagnostic pour ibd, maladie de crohn et colite ulcereuse |
| AUPR279101A0 (en) * | 2001-01-30 | 2001-02-22 | Cytopia Pty Ltd | Protein kinase signalling |
| US20040102455A1 (en) * | 2001-01-30 | 2004-05-27 | Burns Christopher John | Method of inhibiting kinases |
| ATE429511T1 (de) * | 2001-03-01 | 2009-05-15 | Epigenomics Ag | Verfahren zur entwicklung von gensätzen zu diagnostischen und therapeutischen zwecken auf grundlage des expressions- und methylierungsstatus der gene |
| AU2002330039A1 (en) * | 2001-09-17 | 2003-04-01 | Eos Biotechnology, Inc. | Methods of diagnosis of cancer compositions and methods of screening for modulators of cancer |
| GB0122914D0 (en) * | 2001-09-22 | 2001-11-14 | Univ Nottingham | Modulation of stat activity |
-
2002
- 2002-09-24 AU AU2002330713A patent/AU2002330713A1/en not_active Abandoned
- 2002-09-24 AU AU2002329000A patent/AU2002329000A1/en not_active Abandoned
- 2002-09-24 AU AU2002337442A patent/AU2002337442A1/en not_active Abandoned
- 2002-09-24 WO PCT/IB2002/004197 patent/WO2003027295A2/fr not_active Ceased
- 2002-09-24 WO PCT/IB2002/004134 patent/WO2003027276A2/fr not_active Ceased
- 2002-09-24 AU AU2002364889A patent/AU2002364889A1/en not_active Abandoned
- 2002-09-24 WO PCT/IB2002/005830 patent/WO2003043565A2/fr not_active Ceased
- 2002-09-24 WO PCT/IB2002/004158 patent/WO2003027321A2/fr not_active Ceased
- 2002-09-24 WO PCT/IB2002/004123 patent/WO2003027320A2/fr not_active Ceased
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999041985A1 (fr) * | 1998-02-23 | 1999-08-26 | Quark Biotech, Inc. | Secretion de facteurs inhibiteurs de croissance dependant de p53 |
| WO1999065928A2 (fr) * | 1998-06-19 | 1999-12-23 | Genzyme Corporation | Population de polynucleotides isoles de tissus mammaires tumoraux metastatiques ou non metastatiques |
| WO2001057189A2 (fr) * | 2000-02-07 | 2001-08-09 | Quark Biotech, Inc. | Genes de la voie fas |
| WO2001096390A2 (fr) * | 2000-06-09 | 2001-12-20 | Corixa Corporation | Compositions et procedes pour la therapie et le diagnostic du cancer du colon |
| WO2002020849A2 (fr) * | 2000-09-08 | 2002-03-14 | New York University | Marqueurs de gene utiles pour detecter des lesions de la peau dues au rayonnement ultraviolet |
| WO2002020846A2 (fr) * | 2000-09-08 | 2002-03-14 | New York University | Methodes de criblage pour identifier des composes modulant une reponse d'une cellule a l'exposition a un rayonnement ultraviolet |
| WO2002022884A2 (fr) * | 2000-09-12 | 2002-03-21 | Transgenetics Incorporated | Organisation en micro-reseaux de genes cibles de facteur de transcription |
Non-Patent Citations (8)
| Title |
|---|
| ALIZADEH A A ET AL: "DISTINCT TYPES OF DIFFUSE LARGE B-CELL LYMPHOMA IDENTIFIED BY GENE EXPRESSION PROFILING", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 403, 3 February 2000 (2000-02-03), pages 503 - 512, XP002943414, ISSN: 0028-0836 * |
| BLOOD, vol. 94, no. 10 SUPPL. 1 PART 2, 15 November 1999 (1999-11-15), Forty-first Annual Meeting of the American Society of Hematology;New Orleans, Louisiana, USA; December 3-7, 1999, pages 140b, ISSN: 0006-4971 * |
| CHAN KAIMIN ET AL: "NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 93, no. 24, 1996, 1996, pages 13943 - 13948, XP002251107, ISSN: 0027-8424 * |
| CHENAIS BENOIT: "Requirement of GATA-1 and p45 NF-E2 expression in butyric acid-induced erythroid differentiation.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 253, no. 3, 30 December 1998 (1998-12-30), pages 883 - 886, XP002251109, ISSN: 0006-291X * |
| CHUI DAVID H K ET AL: "CDNA cloning of murine Nrf 2 gene, coding for a p45 NF-E2 related transcription factor.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 209, no. 1, 1995, pages 40 - 46, XP002934232, ISSN: 0006-291X * |
| DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 15 November 1999 (1999-11-15), LEHNHARDT ANJA ET AL: "Expression of fNF-E2 mRNA, but not aNF-E2-mRNA correlates with GATA-1 mRNA and NF-E2 p45 protein expression in leukemic cell lines and in primary cells.", XP002251108, Database accession no. PREV200000046601 * |
| MOI P ET AL: "Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 91, no. 21, 1994, 1994, pages 9926 - 9930, XP002964572, ISSN: 0027-8424 * |
| RAMOS-GOMEZ M ET AL: "Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 13 MAR 2001 UNITED STATES, vol. 98, no. 6, 13 March 2001 (2001-03-13), pages 3410 - 3415, XP002251110, ISSN: 0027-8424 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003027321A2 (fr) | 2003-04-03 |
| WO2003027295A2 (fr) | 2003-04-03 |
| AU2002337442A1 (en) | 2003-04-07 |
| WO2003027321A3 (fr) | 2003-11-06 |
| WO2003027320A2 (fr) | 2003-04-03 |
| WO2003027320A3 (fr) | 2003-10-23 |
| AU2002329000A1 (en) | 2003-04-07 |
| AU2002364889A8 (en) | 2003-06-10 |
| AU2002330713A1 (en) | 2003-04-07 |
| WO2003027276A2 (fr) | 2003-04-03 |
| WO2003027295A3 (fr) | 2003-10-16 |
| WO2003027276A3 (fr) | 2004-02-12 |
| WO2003043565A2 (fr) | 2003-05-30 |
| AU2002364889A1 (en) | 2003-06-10 |
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