WO2004016065A3 - SISTEMA Y PROCEDIMIENTO INMUNOCROMATOGRÁFICO PARA LA INDENTIFICACIÓN SIMULTÁNEA DE ANTICUERPOS FRENTE A AGA Y t-TG, Y SU USO EN EL DIAGNOSTICO DE ENFERMEDAD CELIACA - Google Patents

SISTEMA Y PROCEDIMIENTO INMUNOCROMATOGRÁFICO PARA LA INDENTIFICACIÓN SIMULTÁNEA DE ANTICUERPOS FRENTE A AGA Y t-TG, Y SU USO EN EL DIAGNOSTICO DE ENFERMEDAD CELIACA Download PDF

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Publication number
WO2004016065A3
WO2004016065A3 PCT/ES2003/000425 ES0300425W WO2004016065A3 WO 2004016065 A3 WO2004016065 A3 WO 2004016065A3 ES 0300425 W ES0300425 W ES 0300425W WO 2004016065 A3 WO2004016065 A3 WO 2004016065A3
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WO
WIPO (PCT)
Prior art keywords
antibodies
celiac disease
aga
diagnosis
immunochromatography system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/ES2003/000425
Other languages
English (en)
French (fr)
Other versions
WO2004016065A2 (es
Inventor
Corman Enrique Mendez
Asin Carlos Gustavo Genzor
Sierra Susana Gamen
Pamplona Vicente Manu Corbaton
Galindo Antonio Navarro
Ruiz Manuel Villacampa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to DE60311278T priority Critical patent/DE60311278T2/de
Priority to EP03787825A priority patent/EP1538445B1/en
Priority to ES03787825T priority patent/ES2279980T3/es
Priority to AU2003260516A priority patent/AU2003260516A1/en
Publication of WO2004016065A2 publication Critical patent/WO2004016065A2/es
Publication of WO2004016065A3 publication Critical patent/WO2004016065A3/es
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

El objeto de la presente invención es un sistema inmunocromatográfico que comprende dos tiras o sticks inmunocromatográficas que permiten la intensificación simultánea de distintos anticuerpos presentes en una muestra biológica de pacientes con enfermedad celiaca (EC) específicos de los autoantígenos característicos de la EC como el AGA (anticuerpos antigliadinas) y t-TG (transglutaminasa tisular). Otro objeto de la invención lo constituye un procedimiento de identificación de anticuerpos presentes en pacientes con EC basado en el sistema inmunocromatográfico anterior y el uso de ambos, sistema y procedimiento inmunocromatográfico, para el diagnóstico de pacientes con enfermedad celiaca.
PCT/ES2003/000425 2002-08-16 2003-08-14 SISTEMA Y PROCEDIMIENTO INMUNOCROMATOGRÁFICO PARA LA INDENTIFICACIÓN SIMULTÁNEA DE ANTICUERPOS FRENTE A AGA Y t-TG, Y SU USO EN EL DIAGNOSTICO DE ENFERMEDAD CELIACA Ceased WO2004016065A2 (es)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE60311278T DE60311278T2 (de) 2002-08-16 2003-08-14 Immunochromatographiesystem und verfahren zur gleichzeitigen identifikation von aga-und t-tg-antikörpern und verwendung dafür zur diagnose der zöliakiekrankheit
EP03787825A EP1538445B1 (en) 2002-08-16 2003-08-14 Immunochromatography system and method for the simultaneous identification of aga and t-tg antibodies and use thereof for the diagnosis of celiac disease
ES03787825T ES2279980T3 (es) 2002-08-16 2003-08-14 Sistema y procedimiento inmunocromatografico para la identificacion simultanea de anticuerpos frente a aga y t-tg, y su uso en el diagnostico de enfermedad celiaca.
AU2003260516A AU2003260516A1 (en) 2002-08-16 2003-08-14 Immunochromatography system and method for the simultaneous identification of aga and t-tg antibodies and use thereof for the diagnosis of celiac disease

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200201939A ES2214108B1 (es) 2002-08-16 2002-08-16 Sistema y procedimiento inmunocromatografico para la identificacion simultanea de anticuerpos frente a aga y t-tg, y su uso en el diagnostico de enfermedad celiaca.
ESP200201939 2002-08-16

Publications (2)

Publication Number Publication Date
WO2004016065A2 WO2004016065A2 (es) 2004-02-26
WO2004016065A3 true WO2004016065A3 (es) 2004-03-25

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2003/000425 Ceased WO2004016065A2 (es) 2002-08-16 2003-08-14 SISTEMA Y PROCEDIMIENTO INMUNOCROMATOGRÁFICO PARA LA INDENTIFICACIÓN SIMULTÁNEA DE ANTICUERPOS FRENTE A AGA Y t-TG, Y SU USO EN EL DIAGNOSTICO DE ENFERMEDAD CELIACA

Country Status (7)

Country Link
EP (1) EP1538445B1 (es)
AT (1) ATE352037T1 (es)
AU (1) AU2003260516A1 (es)
DE (1) DE60311278T2 (es)
ES (2) ES2214108B1 (es)
PT (1) PT1538445E (es)
WO (1) WO2004016065A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090305303A1 (en) 2006-07-25 2009-12-10 Cecile Besson Duvanel immunochromatography device for the diagnosis of diseases in a sample
CN101261270B (zh) * 2007-03-09 2012-11-07 中国人民解放军军事医学科学院微生物流行病研究所 一种免疫层析多重检测试纸盘及免疫层析多重检测方法
ES2385455B2 (es) * 2010-12-28 2013-09-25 Universidad De Sevilla Determinación de niveles de péptidos inmunogénicos del gluten en muestras humanas.
WO2013098441A1 (es) * 2011-12-29 2013-07-04 Universidad De Sevilla Determinación de niveles de péptidos inmunogénicos del gluten en muestras humanas
US20190094218A1 (en) * 2016-02-23 2019-03-28 Tanaka Kikinzoku Kogyo K.K. Immunochromatography Analysis Device for Detecting Gliadin, Immunochromatography Analysis Kit and Immunochromatography Analysis Method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2141679A1 (es) * 1998-05-22 2000-03-16 Consejo Superior Investigacion Aplicacion de un inmunoensayo visual para la identificacion de la enfermedad celiaca utilizando como antigeno gliadinas de trigo.
EP1164375A2 (en) * 2000-06-07 2001-12-19 Centro De Ingenieria Genetica Y Biotecnologia Assay for anti transglutaminase antibodies

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2141679A1 (es) * 1998-05-22 2000-03-16 Consejo Superior Investigacion Aplicacion de un inmunoensayo visual para la identificacion de la enfermedad celiaca utilizando como antigeno gliadinas de trigo.
EP1164375A2 (en) * 2000-06-07 2001-12-19 Centro De Ingenieria Genetica Y Biotecnologia Assay for anti transglutaminase antibodies

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BAZZIGALUPPI E. ET AL: "Comparison of tissue trans-glutaminase-specific antibody measurements for coelias disease", JOURNAL OF AUTOIMMUNITY, vol. 12, no. 1, February 1999 (1999-02-01), pages 51 - 56, XP001097614 *
PALACIOS S. ET AL: "Anticuerpo antitransglutaminasa: utilidad en el diagnostico de la engermedad celiaca", AN ESP. PEDIATR., vol. 53, no. 6, July 2000 (2000-07-01), pages 542 - 546, XP002976803 *
SORELL L. ET AL: "One-step immunochromatographic assay for screening or coeliac disease", LANCET, vol. 359, no. 9310, March 2002 (2002-03-01), pages 945 - 946, XP001097616 *

Also Published As

Publication number Publication date
ES2214108A1 (es) 2004-09-01
PT1538445E (pt) 2007-04-30
ES2214108B1 (es) 2005-11-16
ES2279980T3 (es) 2007-09-01
AU2003260516A8 (en) 2004-03-03
WO2004016065A2 (es) 2004-02-26
DE60311278D1 (de) 2007-03-08
EP1538445B1 (en) 2007-01-17
ATE352037T1 (de) 2007-02-15
EP1538445A2 (en) 2005-06-08
AU2003260516A1 (en) 2004-03-03
DE60311278T2 (de) 2007-11-15

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