WO2008114732A1 - しわ防止・改善剤 - Google Patents

しわ防止・改善剤 Download PDF

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Publication number
WO2008114732A1
WO2008114732A1 PCT/JP2008/054765 JP2008054765W WO2008114732A1 WO 2008114732 A1 WO2008114732 A1 WO 2008114732A1 JP 2008054765 W JP2008054765 W JP 2008054765W WO 2008114732 A1 WO2008114732 A1 WO 2008114732A1
Authority
WO
WIPO (PCT)
Prior art keywords
wrinkling
preventing
modifying agent
general formula
nitrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/054765
Other languages
English (en)
French (fr)
Inventor
Makoto Tsunenaga
Mikiko Kaminuma
Masaru Suetsugu
Chika Katagiri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shiseido Co Ltd
Original Assignee
Shiseido Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiseido Co Ltd filed Critical Shiseido Co Ltd
Priority to HK10106070.8A priority Critical patent/HK1139857B/xx
Priority to US12/530,841 priority patent/US8173705B2/en
Priority to CN2008800086096A priority patent/CN101677931B/zh
Priority to EP08722161.0A priority patent/EP2123253B1/en
Priority to JP2009505201A priority patent/JP5501758B2/ja
Publication of WO2008114732A1 publication Critical patent/WO2008114732A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

　加齢や光老化等の皮膚バリア機能低下によって生じるしわ、すなわち、図形しわあるいは線状しわを防止・改善する効果に優れた、しわ防止・改善剤を提供する。 　下記一般式（１）で表されるγ－アミノ酪酸誘導体又は一般式（３）で示されるＮ，Ｎ，Ｎ－トリメチルγ－アミノ酪酸、及びそれらの塩からなる群から選ばれる化合物の１種又は２種以上からなるしわ防止・改善剤。   （一般式（１）中、Ｒ１及びＲ２はそれぞれ独立に水素原子、炭素数１～３のアルキル基、ベンジルオキシカルボニル基、シクロヘキシル基、シクロヘキサンメチル基、シクロヘキサンカルボニル基、窒素原子を含んで形成されるグアニジノ基、窒素原子を含んで形成されるウレイド基、一般式（２）で表される基のいずれかを表す。また、Ｒ１及びＲ２は、Ｒ１及びＲ２によりピペリジン環、モルホリン環又はピロリジン環を構成しても構わない。なお、Ｒ１及びＲ２が同時に水素原子であることはない。）
PCT/JP2008/054765 2007-03-16 2008-03-14 しわ防止・改善剤 Ceased WO2008114732A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
HK10106070.8A HK1139857B (en) 2007-03-16 2008-03-14 Wrinkling-preventing and-modifying agent
US12/530,841 US8173705B2 (en) 2007-03-16 2008-03-14 Agent for alleviating wrinkles
CN2008800086096A CN101677931B (zh) 2007-03-16 2008-03-14 皱纹防止、改善剂
EP08722161.0A EP2123253B1 (en) 2007-03-16 2008-03-14 Wrinkling-preventing and -alleviating agent
JP2009505201A JP5501758B2 (ja) 2007-03-16 2008-03-14 しわ防止・改善剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007069134 2007-03-16
JP2007-069134 2007-03-16

Publications (1)

Publication Number Publication Date
WO2008114732A1 true WO2008114732A1 (ja) 2008-09-25

Family

ID=39765840

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/054765 Ceased WO2008114732A1 (ja) 2007-03-16 2008-03-14 しわ防止・改善剤

Country Status (6)

Country Link
US (1) US8173705B2 (ja)
EP (1) EP2123253B1 (ja)
JP (1) JP5501758B2 (ja)
KR (1) KR101560840B1 (ja)
CN (1) CN101677931B (ja)
WO (1) WO2008114732A1 (ja)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009242341A (ja) * 2008-03-31 2009-10-22 Shiseido Co Ltd Ｎ−ベンゼンスルホニル−γ−アミノ酪酸及び／またはその塩を活性成分とするＳＣＣＡ−１産生抑制剤
WO2010126102A1 (ja) * 2009-04-28 2010-11-04 株式会社資生堂 カルボキシアミド誘導体及び／またはその塩を活性成分とするｓｃｃａ-１産生抑制剤
WO2012124738A1 (ja) * 2011-03-15 2012-09-20 株式会社資生堂 ブレオマイシン水解酵素産生促進剤
JP2015134737A (ja) * 2014-01-18 2015-07-27 共栄化学工業株式会社 皮膚外用剤
JP2016509052A (ja) * 2013-02-25 2016-03-24 ロレアル ゲル型化粧料組成物
WO2016063991A1 (ja) * 2014-10-24 2016-04-28 株式会社資生堂 角層剥離の抑制又は亢進に起因する肌状態を改善するための美容方法及び評価方法
JP2016513121A (ja) * 2013-02-25 2016-05-12 ロレアル ゲル型化粧料組成物
CN106038345A (zh) * 2016-06-06 2016-10-26 山东水晶生物科技股份有限公司 一种含伽玛氨基丁酸的面膜
WO2020158643A1 (ja) * 2019-01-29 2020-08-06 丸善製薬株式会社 外用剤
JP2022003017A (ja) * 2020-06-23 2022-01-11 株式会社ノエビア 皮膚外用剤
JP2022507332A (ja) * 2018-11-13 2022-01-18 彭険峰 動物飼料添加剤の調製におけるアミノ酸のアシル誘導体の用途
US11311465B2 (en) 2014-08-28 2022-04-26 L'oreal Gel-type cosmetic composition with improved staying power
EP3914242A4 (en) * 2019-01-23 2023-02-01 Epitracker, Inc. COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF QUALITY OF AGING AND LONGEVITY DISORDERS
US11951088B2 (en) 2017-10-23 2024-04-09 Epitracker, Inc. Fatty acid analogs and their use in the treatment of conditions related to metabolic syndrome
US11992473B2 (en) 2018-05-23 2024-05-28 Epitracker, Inc. Compositions and methods for diagnosis and treatment of conditions related to the quality of aging and longevity
US12370166B2 (en) 2021-11-03 2025-07-29 Epitracker, Inc. Pentadecanoylcarnitine for treatment of conditions related to the quality of aging and longevity
US12427179B2 (en) 2019-01-09 2025-09-30 Epitracker, Inc. Compositions and methods for diagnosis and treatment of neurodegenerative diseases
US12440473B2 (en) 2019-03-04 2025-10-14 Epitracker, Inc. Fatty acid analogs and their use in the treatment of cognitive impairment, behavioral conditions, and chronic pain

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2731917C1 (ru) * 2016-11-28 2020-09-09 Пола Кемикал Индастриз, Инк. Средство для устранения морщин
CN116209433B (zh) * 2020-08-20 2025-05-23 俄勒冈健康科学大学 小分子白蛋白结合剂

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WO2002053127A1 (en) * 2000-12-28 2002-07-11 Shiseido Company, Ltd. Agents for inhibiting or restoring skin damage caused by drying and method of evaluating the same
WO2003053466A1 (fr) * 2001-12-13 2003-07-03 Shiseido Company, Ltd. Accelerateurs de reparation de la fonction barriere de la peau
JP2005027343A (ja) 1993-06-07 2005-01-27 Microsoft Corp インテリジェントファクシミリのユーザインタフェース及びその使用方法
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JPH07116146A (ja) 1993-10-21 1995-05-09 Shiseido Co Ltd シワの測定方法及び装置
JPH09202710A (ja) * 1995-11-20 1997-08-05 Kao Corp しわ改善剤
WO2002053127A1 (en) * 2000-12-28 2002-07-11 Shiseido Company, Ltd. Agents for inhibiting or restoring skin damage caused by drying and method of evaluating the same
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JP2007069134A (ja) 2005-09-07 2007-03-22 Dainippon Printing Co Ltd 減圧装置

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Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009242341A (ja) * 2008-03-31 2009-10-22 Shiseido Co Ltd Ｎ−ベンゼンスルホニル−γ−アミノ酪酸及び／またはその塩を活性成分とするＳＣＣＡ−１産生抑制剤
WO2010126102A1 (ja) * 2009-04-28 2010-11-04 株式会社資生堂 カルボキシアミド誘導体及び／またはその塩を活性成分とするｓｃｃａ-１産生抑制剤
WO2012124738A1 (ja) * 2011-03-15 2012-09-20 株式会社資生堂 ブレオマイシン水解酵素産生促進剤
JP2012193136A (ja) * 2011-03-15 2012-10-11 Shiseido Co Ltd ブレオマイシン水解酵素産生促進剤
US10238584B2 (en) 2013-02-25 2019-03-26 L'oreal Gel-type cosmetic composition
JP2016509052A (ja) * 2013-02-25 2016-03-24 ロレアル ゲル型化粧料組成物
JP2016513121A (ja) * 2013-02-25 2016-05-12 ロレアル ゲル型化粧料組成物
US10398631B2 (en) 2013-02-25 2019-09-03 L'oreal Gel-type cosmetic composition
JP2015134737A (ja) * 2014-01-18 2015-07-27 共栄化学工業株式会社 皮膚外用剤
US11311465B2 (en) 2014-08-28 2022-04-26 L'oreal Gel-type cosmetic composition with improved staying power
WO2016063991A1 (ja) * 2014-10-24 2016-04-28 株式会社資生堂 角層剥離の抑制又は亢進に起因する肌状態を改善するための美容方法及び評価方法
JPWO2016063991A1 (ja) * 2014-10-24 2017-08-31 株式会社 資生堂 角層剥離の抑制又は亢進に起因する肌状態を改善するための美容方法及び評価方法
CN106038345A (zh) * 2016-06-06 2016-10-26 山东水晶生物科技股份有限公司 一种含伽玛氨基丁酸的面膜
US11951088B2 (en) 2017-10-23 2024-04-09 Epitracker, Inc. Fatty acid analogs and their use in the treatment of conditions related to metabolic syndrome
US11992473B2 (en) 2018-05-23 2024-05-28 Epitracker, Inc. Compositions and methods for diagnosis and treatment of conditions related to the quality of aging and longevity
JP7348459B2 (ja) 2018-11-13 2023-09-21 アニファー テクノロジーズ ピー ティー ワイ エル ティー ディー 動物飼料添加剤の調製におけるアミノ酸のアシル誘導体の使用、飼料用組成物及び動物飼料の調製における飼料用組成物の使用。
JP2022507332A (ja) * 2018-11-13 2022-01-18 彭険峰 動物飼料添加剤の調製におけるアミノ酸のアシル誘導体の用途
US12427179B2 (en) 2019-01-09 2025-09-30 Epitracker, Inc. Compositions and methods for diagnosis and treatment of neurodegenerative diseases
EP3914242A4 (en) * 2019-01-23 2023-02-01 Epitracker, Inc. COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF QUALITY OF AGING AND LONGEVITY DISORDERS
JPWO2020158643A1 (ja) * 2019-01-29 2021-12-02 丸善製薬株式会社 外用剤
WO2020158643A1 (ja) * 2019-01-29 2020-08-06 丸善製薬株式会社 外用剤
US12440473B2 (en) 2019-03-04 2025-10-14 Epitracker, Inc. Fatty acid analogs and their use in the treatment of cognitive impairment, behavioral conditions, and chronic pain
JP2022003017A (ja) * 2020-06-23 2022-01-11 株式会社ノエビア 皮膚外用剤
US12370166B2 (en) 2021-11-03 2025-07-29 Epitracker, Inc. Pentadecanoylcarnitine for treatment of conditions related to the quality of aging and longevity

Also Published As

Publication number Publication date
CN101677931A (zh) 2010-03-24
US8173705B2 (en) 2012-05-08
KR20090122443A (ko) 2009-11-30
KR101560840B1 (ko) 2015-10-15
EP2123253A1 (en) 2009-11-25
EP2123253A4 (en) 2013-03-13
CN101677931B (zh) 2013-01-02
EP2123253B1 (en) 2017-06-28
US20100113450A1 (en) 2010-05-06
JPWO2008114732A1 (ja) 2010-07-01
HK1139857A1 (en) 2010-09-30
JP5501758B2 (ja) 2014-05-28

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