WO2009124794A1 - Tambour d'enrobage fermé totalement perforé - Google Patents

Tambour d'enrobage fermé totalement perforé Download PDF

Info

Publication number
WO2009124794A1
WO2009124794A1 PCT/EP2009/051442 EP2009051442W WO2009124794A1 WO 2009124794 A1 WO2009124794 A1 WO 2009124794A1 EP 2009051442 W EP2009051442 W EP 2009051442W WO 2009124794 A1 WO2009124794 A1 WO 2009124794A1
Authority
WO
WIPO (PCT)
Prior art keywords
drum
air
tablets
wall
coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2009/051442
Other languages
English (en)
Inventor
Alfons Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gebrueder Loedige Maschinenbau GmbH
Original Assignee
Gebrueder Loedige Maschinenbau GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gebrueder Loedige Maschinenbau GmbH filed Critical Gebrueder Loedige Maschinenbau GmbH
Publication of WO2009124794A1 publication Critical patent/WO2009124794A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005—Coating of tablets or the like
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/0002—Processes of manufacture not relating to composition and compounding ingredients
    • A23G3/0095—Coating by tumbling with a liquid or powder, spraying device-associated, drum, rotating pan
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/02—Apparatus specially adapted for manufacture or treatment of sweetmeats or confectionery; Accessories therefor
    • A23G3/20—Apparatus for coating or filling sweetmeats or confectionery
    • A23G3/26—Apparatus for coating by tumbling with a liquid or powder, spraying device-associated, drum, rotating pan
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/02—Apparatus specially adapted for manufacture or treatment of chewing gum
    • A23G4/025—Apparatus specially adapted for manufacture or treatment of chewing gum for coating or surface-finishing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/006—Coating of the granules without description of the process or the device by which the granules are obtained
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/12—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in rotating drums
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B13/00—Machines or plants for applying liquids or other fluent materials to surfaces of objects or other work by spraying, not covered by groups B05B1/00 - B05B11/00
    • B05B13/02—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work
    • B05B13/0221—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work characterised by the means for moving or conveying the objects or other work, e.g. conveyor belts
    • B05B13/025—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work characterised by the means for moving or conveying the objects or other work, e.g. conveyor belts the objects or work being present in bulk
    • B05B13/0257—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work characterised by the means for moving or conveying the objects or other work, e.g. conveyor belts the objects or work being present in bulk in a moving container, e.g. a rotatable foraminous drum

Definitions

  • the invention relates to a device and method for coating tablets.
  • Document WO 2005/1 23267 Al discloses a device for coating tablets comprising a horizontally supported, rotatable drum .
  • the drum has perforated segments.
  • the drum comprises an emptying opening and a lockable opening provided at an end side of the drum .
  • the tablets are put into the drum through the lockable opening .
  • the tablets are coated in the drum .
  • the emptying opening is part of the circumference of the drum. If the emptying opening is located at the bottom, the drum can be easily emptied, due to gravity, through this opening .
  • a mixing mechanism can be provided within the drum . This is made such that the tablets located in the drum are conveyed towards the end side comprising the door upon rotation in a direction opposite to the direction of rotation during mixing or coating, in order to thus be able to remove tablets through the lateral opening, for example.
  • the coating agent to be applied onto the tablets is introduced into the drum via a first feed, as seen from the end side having the lateral opening.
  • aqueous suspensions or paints, or suspensions or paints provided with organic solvents are thus introduced into the interior of the mixing container via the first feed .
  • the coating agent exits via at least one downwardly directed nozzle.
  • the nozzle is made such that the suspension is sprayed around on the inside of the drum .
  • the mixing container is slowly rotated about the horizontal axis in the process.
  • the drum typically rotates at up to 25 rotations per minute.
  • conditioned air i .e. air of a certain temperature, dried and filtered
  • conditioned air i .e. air of a certain temperature, dried and filtered
  • the air stream causes the coating agent deposited on a tablet to dry.
  • the punched sheet in the state of the art is arranged above the nozzle and in such a way as to face in the same direction as the nozzle.
  • the air stream then exits again through the perforation of the drum segments via a suction device.
  • the perforation is distributed over the circumference of the drum .
  • four segments of equal size distributed over the circumference may be provided with the perforation .
  • coating material for the tablets is fed via an end side of the drum, and air is fed via the opposite side.
  • Dust is inevitably generated during the coating process in the drum, which can exit unimpeded through the perforation, soiling the surrounding housing.
  • the dust load leads to a correspondingly large cleaning effort with respect to the coating device. It is the object of the present invention to avoid the dust loads in devices for coating tablets.
  • a drum for coating tablets is provided, the circumference of which is provided with an inner and an outer wall.
  • the inner wall has perforations.
  • the drum comprises means for suctioning air exiting from the perforation . Dust is suctioned off together with the air. The dust can now be separated from the suctioned-off air and can be disposed of . A dust load and a very laborious cleaning process of the housing of the device for coating tablets and parts located therein can thus be avoided.
  • the means for suctioning off air exiting the perforation preferably comprise at least one suction opening disposed adjacent the circumference at an end side of the drum .
  • the opening can be combined with a ventilator or a comparable means in order to suction off air from the area between the inner and the outer wall .
  • Figure 1 shows a drum 1 for coating tablets.
  • the circumference of the drum is formed by an inner wall 2 and an outer wall 3. Two segments of the outer wall are not shown in Fig. 1 in order to be able to view the segments of the inner wall beneath them .
  • the inner wall 2 is provided with a perforation 4. Between the inner wall and the outer wall, there are partition walls 5 in regular intervals which divide the interspace between the inner and the outer wall into individual chambers 1 0 (see Fig. 2) . Because of the partition walls, air cannot move from one chamber directly to an adjacent chamber. If air enters one of the chambers through the perforation 4, the chamber is preferably screened off by the walls in such a way that the air can only be passed on through a lateral suction opening 6.
  • this configuration makes suctioning off the air from the individual chambers via the openings in a controlled manner.
  • the uncontrolled and undesired flow of air from the drum towards the outside can thus be avoided .
  • the air is preferably only exhausted from the drum via perforated segments beneath it in order to thus coat in a suitable and effective manner.
  • air is only suctioned off from a chamber if it is located at the bottom . This ensures that the air flows in the intended manner.
  • the drum comprises one suction opening 6 as well as a conduit 7 per chamber, via which the air is suctioned from the respective chamber.
  • a discharge helix 8 can be provided in the interior of the drum . After the coating process, the direction of rotation of the drum is changed in such a way that the coated tablets are transported towards the opening provided in an end wall by the helices. The tablets can now be easily removed through the opening . This embodiment avoids a greater technical effort which would otherwise be necessary for a removal opening through the inner and outer wall.
  • Fig. 2 shows a device for coating tablets having a drum 1 shown in Fig. 1 .
  • Air and the coating means are directed in a downward direction towards the tablets to be coated, namely in particular in the way known from the printed publication WO 2005/1 23267 Al .
  • a conduit 7 of the drum is located at the bottom, its outer opening is adjacent to a suction opening 9 which is adjacent to the drum, via which opening the air is suctioned from the corresponding chamber 1 0.
  • a suction opening 9 adjacent to the drum is provided only in the bottom area in order to thus achieve the air only being suctioned from a chamber 1 0 if the chamber is located at the bottom .
  • a suspension used for the coating process is fed laterally via a first side of the drum, and the air is fed laterally at the opposite side. It is thus accomplished that there is more room at the side from which the operation is carried out by the user as compared to the case where suspension and air is fed through an end wall .
  • the feed as well the nozzle via which the suspension is fed must be cleaned from time to time. It is therefore advantageous to provide this feed from the front side, i .e. from the side of the operator. This reduces the cleaning effort. No or a significantly smaller cleaning effort is required for the air feed . Therefore, the air feed is preferably carried out from the rear, which is comparatively hard to access.
  • the suspension is being fed to the drum beneath or at the level of its axis of rotation.
  • the air is fed to the drum entirely or predominantly above the axis of rotation.
  • the air, coming from above can be directed towards the material to be mixed, and it can transport the nebulized suspension towards the material to be mixed or the tablets in the process.
  • the material to be mixed that is, the tablets, roll around in the interior of the drum, they are, on average, not located at the lowermost point during the coating process, but slightly displaced laterally from this lowermost point, depending on the speed of rotation of the drum .
  • this is taken into account when arranging the feeds of air and suspension by the means for feeding air and suspension being oriented such that the suspension as well as the air are being directed towards this laterally displaced point.
  • the punched plate as well as the nozzle are preferably oriented not exactly vertically, but correspondingly obliquely. The punched plate is then oriented in an approximately parallel direction to the surface which the tablets form during coating .
  • air and suspension exit in the same direction from the respective feeding means.
  • the direction of discharge of air and suspension then enclose an angle with the vertical that is larger than 0° and smaller than 90°.
  • this angle is between 1 0° and 60°, in particular between 25° to 50°, at the common speeds of rotation of up to 25 revolutions per minute. Therefore, one or more suction openings 9, which are adjacent to a conduit 7 of the drum from the outside, are provided correspondingly offset from the lowermost point. In that case, there are preferably no further suction openings 9 beyond that.
  • Air can be fed, for example, via an annular recess at the front side of the drum .
  • the drum at its rear comprises a circular plate which is rotatably connected to the rest of the drum .
  • the rotatable connection is formed to be sealing .
  • the drum rotates, and not the circular plate.
  • the air is passed, via an appropriate passage, through this circular plate.
  • the technical area of the device for example, electronic controllers, motors etc, is then arranged behind the rear of the drum . This technical area is thus separated from the production area, which is an advantage with respect to a trouble-free operation .

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention porte sur un tambour, sur un dispositif et sur un procédé pour enrober des cachets. Le tambour (1) pour enrober les cachets a une périphérie formée par une paroi externe (3) et une paroi interne totalement ou partiellement perforée (2). Des moyens (6, 7) pour aspirer de l'air sortant de la perforation (4) sont présents. L'invention porte également sur un dispositif pour enrober comprenant un tel tambour.
PCT/EP2009/051442 2008-04-10 2009-02-09 Tambour d'enrobage fermé totalement perforé Ceased WO2009124794A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008001104.5 2008-04-10
DE102008001104A DE102008001104A1 (de) 2008-04-10 2008-04-10 Geschlossen vollperforierte Coating Trommel

Publications (1)

Publication Number Publication Date
WO2009124794A1 true WO2009124794A1 (fr) 2009-10-15

Family

ID=40456811

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/051442 Ceased WO2009124794A1 (fr) 2008-04-10 2009-02-09 Tambour d'enrobage fermé totalement perforé

Country Status (2)

Country Link
DE (1) DE102008001104A1 (fr)
WO (1) WO2009124794A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3089756A1 (fr) * 2018-12-17 2020-06-19 Roquette Freres Formes solides dragéifiées présentant une stabilité améliorée
JP2023093686A (ja) * 2017-06-19 2023-07-04 ロケット フレール 新規な糖衣コーティング方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19507281A1 (de) * 1994-03-03 1995-09-07 Freunt Ind Co Ltd Trogüberzugsvorrichtung
EP0744212A2 (fr) * 1995-05-24 1996-11-27 L.B. BOHLE PHARMATECHNIK GmbH Tambour pour enrober
US5589225A (en) * 1994-03-11 1996-12-31 Freund Industrial Co., Ltd. Granulating-coating apparatus and granulating and coating method using the same
EP1402941A1 (fr) * 2001-06-22 2004-03-31 Kabushiki Kaisha Powrex Dispositif de traitement de particules de poudre
US20070209582A1 (en) * 2006-03-10 2007-09-13 Narimichi Takei Coating apparatus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3834347A (en) * 1971-06-16 1974-09-10 Freunt Ind Co Ltd Tablet coating apparatus
JPS5125694U (fr) * 1974-08-17 1976-02-25
JPS5544380A (en) * 1978-09-26 1980-03-28 Okawara Mfg Co Ltd Drafty rotary drum type coater
DE3302589A1 (de) * 1982-01-29 1984-02-09 Glatt Maschinen- und Apparatebau AG, 4133 Pratteln Vorrichtung zum ueberziehen von teilchen, insbesondere arzneimittel-teilchen, und verwendung der vorrichtung
DE3207869A1 (de) * 1982-03-05 1983-09-15 Boehringer Mannheim Gmbh, 6800 Mannheim Vorrichtung zum ueberziehen eines dragiergutes
DE4445618C2 (de) * 1994-12-21 1997-09-04 Loedige Maschbau Gmbh Geb Vorrichtung für die Filmlackierung und/oder Zuckerdragierung
US6511541B2 (en) * 2001-02-27 2003-01-28 Spray Dynamics, Ltd. Powder applicator for particulate material coating
EP1607139B1 (fr) 2004-06-17 2009-01-21 Gebr. Lödige Maschinenbau Gesellschaft mbH Appareil et méthode pour le revêtement des pilules avec un tambour rotatif
DE102005020992B3 (de) * 2005-05-03 2006-12-14 Uhde Gmbh Mehrstufige Coatingvorrichtung für Formkörper

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19507281A1 (de) * 1994-03-03 1995-09-07 Freunt Ind Co Ltd Trogüberzugsvorrichtung
US5589225A (en) * 1994-03-11 1996-12-31 Freund Industrial Co., Ltd. Granulating-coating apparatus and granulating and coating method using the same
EP0744212A2 (fr) * 1995-05-24 1996-11-27 L.B. BOHLE PHARMATECHNIK GmbH Tambour pour enrober
EP1402941A1 (fr) * 2001-06-22 2004-03-31 Kabushiki Kaisha Powrex Dispositif de traitement de particules de poudre
US20070209582A1 (en) * 2006-03-10 2007-09-13 Narimichi Takei Coating apparatus

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023093686A (ja) * 2017-06-19 2023-07-04 ロケット フレール 新規な糖衣コーティング方法
JP7715355B2 (ja) 2017-06-19 2025-07-30 ロケット フレール 新規な糖衣コーティング方法
FR3089756A1 (fr) * 2018-12-17 2020-06-19 Roquette Freres Formes solides dragéifiées présentant une stabilité améliorée
WO2020128290A1 (fr) * 2018-12-17 2020-06-25 Roquette Freres Formes solides dragéifiées présentant une stabilité améliorée
CN113347964A (zh) * 2018-12-17 2021-09-03 罗盖特公司 具有改善的稳定性的包糖衣的固体形式

Also Published As

Publication number Publication date
DE102008001104A1 (de) 2009-10-15

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