WO2010077795A3 - Compositions et méthodes pour une santé buccale améliorée - Google Patents

Compositions et méthodes pour une santé buccale améliorée Download PDF

Info

Publication number
WO2010077795A3
WO2010077795A3 PCT/US2009/067809 US2009067809W WO2010077795A3 WO 2010077795 A3 WO2010077795 A3 WO 2010077795A3 US 2009067809 W US2009067809 W US 2009067809W WO 2010077795 A3 WO2010077795 A3 WO 2010077795A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
methods
oral health
health
pneumonia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2009/067809
Other languages
English (en)
Other versions
WO2010077795A2 (fr
Inventor
Zamzam Kabiry Roughead
Kala Marie Kaspar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nestec SA
Original Assignee
Nestec SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2011540944A priority Critical patent/JP2012512171A/ja
Priority to AU2009333388A priority patent/AU2009333388A1/en
Priority to EP09793395A priority patent/EP2379091A2/fr
Priority to CN2009801503950A priority patent/CN102245191A/zh
Priority to US13/139,787 priority patent/US20120039860A1/en
Priority to RU2011129693/15A priority patent/RU2011129693A/ru
Priority to CA2747231A priority patent/CA2747231A1/fr
Priority to BRPI0922924A priority patent/BRPI0922924A2/pt
Application filed by Nestec SA filed Critical Nestec SA
Priority to MX2011006488A priority patent/MX2011006488A/es
Priority to SG2011040367A priority patent/SG171930A1/en
Publication of WO2010077795A2 publication Critical patent/WO2010077795A2/fr
Publication of WO2010077795A3 publication Critical patent/WO2010077795A3/fr
Anticipated expiration legal-status Critical
Priority to ZA2011/05261A priority patent/ZA201105261B/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G3/366—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing microorganisms, enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention porte sur des compositions et des méthodes de prévention et de traitement de maladies associées à la santé buccale. Dans un mode de réalisation général, les compositions et méthodes de la présente invention peuvent améliorer la santé buccale en réduisant l'incidence de pneumonies par aspiration, de pneumonies extrahospitalières et de pneumonies nosocomiales, en permettant de réduire la gingivite et la plaque dentaire, et en assurant une flore de la langue améliorée. Par l'utilisation de probiotiques naturellement présents dans la cavité buccale ou le tractus gastro-intestinal, les compositions et méthodes selon les modes de réalisation de la présente invention peuvent réduire les bacilles gram-négatifs anaérobies et augmenter la présence de la flore normale. Grâce à la prévention et le traitement de problèmes associés à la santé buccale chez un patient, des problèmes de santé ultérieurs peuvent être prévenus ou limités, ce qui peut conduire à des coûts de soin de santé réduits pour le patient dans le futur.
PCT/US2009/067809 2008-04-10 2009-12-14 Compositions et méthodes pour une santé buccale améliorée Ceased WO2010077795A2 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CA2747231A CA2747231A1 (fr) 2008-12-16 2009-12-14 Compositions et methodes pour une sante buccale amelioree
EP09793395A EP2379091A2 (fr) 2008-12-16 2009-12-14 Compositions et méthodes pour une santé buccale améliorée
CN2009801503950A CN102245191A (zh) 2008-12-16 2009-12-14 用于改善口腔健康的组合物和方法
US13/139,787 US20120039860A1 (en) 2008-04-10 2009-12-14 Compositions and methods for improved oral health
RU2011129693/15A RU2011129693A (ru) 2008-12-16 2009-12-14 Композиции и способы улучшения здоровья полости рта
BRPI0922924A BRPI0922924A2 (pt) 2008-12-16 2009-12-14 composições para melhoria da saúde oral, método de uso de uma composição e uso de pelo menos uma bactéria benéfica para a preparação de uma composição para melhoria da saúde oral
MX2011006488A MX2011006488A (es) 2008-12-16 2009-12-14 Composiciones y metodos para la salud oral mejorada.
JP2011540944A JP2012512171A (ja) 2008-12-16 2009-12-14 改善された口腔健康のための組成物及び方法
AU2009333388A AU2009333388A1 (en) 2008-12-16 2009-12-14 Compositions and methods for improved oral health
SG2011040367A SG171930A1 (en) 2008-12-16 2009-12-14 Compositions and methods for improved oral health
ZA2011/05261A ZA201105261B (en) 2008-12-16 2011-07-15 Compositions and methods for improved oral health

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12290308P 2008-12-16 2008-12-16
US61/122,903 2008-12-16
US24082909P 2009-09-09 2009-09-09
US61/240,829 2009-09-09

Publications (2)

Publication Number Publication Date
WO2010077795A2 WO2010077795A2 (fr) 2010-07-08
WO2010077795A3 true WO2010077795A3 (fr) 2010-12-09

Family

ID=42236618

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/067809 Ceased WO2010077795A2 (fr) 2008-04-10 2009-12-14 Compositions et méthodes pour une santé buccale améliorée

Country Status (11)

Country Link
EP (1) EP2379091A2 (fr)
JP (1) JP2012512171A (fr)
CN (1) CN102245191A (fr)
AU (1) AU2009333388A1 (fr)
BR (1) BRPI0922924A2 (fr)
CA (1) CA2747231A1 (fr)
MX (1) MX2011006488A (fr)
RU (1) RU2011129693A (fr)
SG (1) SG171930A1 (fr)
WO (1) WO2010077795A2 (fr)
ZA (1) ZA201105261B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2420580A1 (fr) * 2010-08-18 2012-02-22 AB-Biotics, S.A. Composition probiotique pour santé buccale
KR101166798B1 (ko) * 2011-12-19 2012-07-26 김대현 락토바실러스 애시도필러스 엘비의 사균을 포함하는 알레르기 질환의 치료 또는 예방용 의약 조성물
CN102533790B (zh) * 2011-12-23 2013-10-02 光明乳业股份有限公司 一种检测植物乳杆菌st-ⅲ的pcr检测方法及其引物和试剂盒
CA2783414A1 (fr) 2012-07-22 2014-01-22 Integral Medical Inc. Composition probiotique
JP2016513631A (ja) 2013-03-14 2016-05-16 ネステク ソシエテ アノニム ラクトバチルス・プランタルムｎｃｃ２９３６調製物及び口腔健康
CN104825380A (zh) * 2015-04-21 2015-08-12 溧水区人民医院 一种快速恢复口腔正常菌群的护理液及其制备方法
CN105193857A (zh) * 2015-09-25 2015-12-30 南昌大学 一种人工培养口腔细菌移植在口腔疾病治疗中的应用
CN105193859A (zh) * 2015-09-25 2015-12-30 南昌大学 一种天然口腔细菌移植在口腔疾病治疗中的应用
EP3405205B1 (fr) 2016-01-19 2020-07-15 Symrise AG Probiotiques pour utilisation en tant qu'agents anti-inflammatoires dans la cavité buccale
GB201600975D0 (en) 2016-01-19 2016-03-02 Probi Ab Novel strain of probiotic bacteria and compositions and uses thereof
EP3196318A1 (fr) 2016-01-19 2017-07-26 Symrise AG Probiotiques pour modifier la composition des biofilms oraux
CN106727819A (zh) * 2016-12-09 2017-05-31 湖南文理学院 朝鲜蓟口腔清新剂的制备方法
EP3351259A1 (fr) 2017-01-18 2018-07-25 Symrise AG Probiotiques pour agrégation avec des espèces associées à une maladie dans la cavité buccale
CN107158040B (zh) * 2017-04-12 2020-12-08 华南农业大学 一种口腔微生态制剂及其制备方法
WO2020001747A1 (fr) 2018-06-26 2020-01-02 Symrise Ag Lactobacillus plantarum pour soins de la peau
CN108553406B (zh) * 2018-07-24 2020-12-01 北京斯利安药业有限公司 一种组合物、其应用及具有改善口腔健康作用的口服制剂
KR102555748B1 (ko) * 2023-03-23 2023-07-17 주식회사 그린스토어 항균, 항진균, 항염 활성 및 치아 우식 억제 활성을 갖는 신규한 스트렙토코커스 살리바리우스 균주 kccm13161p 및 이를 포함하는 구강용 조성물
CN118028182B (zh) * 2024-04-12 2024-06-18 四川厌氧生物科技有限责任公司 一种改善口腔健康的约翰逊氏乳杆菌及其用途

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000009080A1 (fr) * 1998-08-12 2000-02-24 Societe Des Produits Nestle S.A. Incorporation de bacteries lactiques exogenes a la flore microbienne de la cavite buccale
EP1159951A1 (fr) * 2000-06-02 2001-12-05 Societe Des Produits Nestle S.A. Utilisation de souches de bacteries d'acide lactique exogenes pour le traitement de maladies correspondant aux Actinomyces naeslundii
US20040101495A1 (en) * 2002-11-27 2004-05-27 Leena Nase Method for improving dental health
WO2010008879A2 (fr) * 2008-06-24 2010-01-21 Wm. Wrigley Jr. Company Procédé de fabrication de gomme à mâcher probiotique
WO2010054439A1 (fr) * 2008-11-14 2010-05-20 Unistraw Patent Holdings Limited Compositions probiotiques, procédés et appareil pour leur administration

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1260227A1 (fr) * 2001-05-23 2002-11-27 Societe Des Produits Nestle S.A. L'acide lipoteichoique des bacteries lactiques et son utilisation pour moduler des responses immunitaites induites par des bacteries a gram negatif, gram positif

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000009080A1 (fr) * 1998-08-12 2000-02-24 Societe Des Produits Nestle S.A. Incorporation de bacteries lactiques exogenes a la flore microbienne de la cavite buccale
EP1159951A1 (fr) * 2000-06-02 2001-12-05 Societe Des Produits Nestle S.A. Utilisation de souches de bacteries d'acide lactique exogenes pour le traitement de maladies correspondant aux Actinomyces naeslundii
US20040101495A1 (en) * 2002-11-27 2004-05-27 Leena Nase Method for improving dental health
WO2010008879A2 (fr) * 2008-06-24 2010-01-21 Wm. Wrigley Jr. Company Procédé de fabrication de gomme à mâcher probiotique
WO2010054439A1 (fr) * 2008-11-14 2010-05-20 Unistraw Patent Holdings Limited Compositions probiotiques, procédés et appareil pour leur administration

Non-Patent Citations (26)

* Cited by examiner, † Cited by third party
Title
AHOLA A J ET AL: "Short-term consumption of probiotic-containing cheese and its effect on dental caries risk factors.", ARCHIVES OF ORAL BIOLOGY, vol. 47, no. 11, November 2002 (2002-11-01), pages 799 - 804, XP002604329, ISSN: 0003-9969 *
BURTON J P ET AL: "A preliminary study of the effect of probiotic Streptococcus salivarius K12 on oral malodour parameters", April 2006, JOURNAL OF APPLIED MICROBIOLOGY, VOL. 100, NR. 4, PAGE(S) 754-764, ISSN: 1364-5072, XP002594147 *
BURTON J P ET AL: "Safety assessment of the oral cavity probiotic Streptococcus salivarius K12", April 2006, APPLIED AND ENVIRONMENTAL MICROBIOLOGY APRIL 2006 AMERICAN SOCIETY FOR MICROBIOLOGY US, VOL. 72, NR. 4, PAGE(S) 3050 - 3053, XP002594146 *
BURTON J P ET AL: "The rationale and potential for the reduction of oral malodour using Streptococcus salivarius probiotics.", 2005, ORAL DISEASES 2005 LNKD- PUBMED:15752094, VOL. 11 SUPPL 1, PAGE(S) 29 - 31, ISSN: 1601-0825, XP002594149 *
CAGLAR E ET AL: "Bacteriotherapy and probiotics' role on oral health", May 2005, ORAL DISEASES 200505 DK, VOL. 11, NR. 3, PAGE(S) 131 - 137, ISSN: 1354-523X, XP002594144 *
CAGLAR ESBER ET AL: "A probiotic lozenge administered medical device and its effect on salivary mutans streptococci and lactobacilli.", INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY / THE BRITISH PAEDODONTIC SOCIETY [AND] THE INTERNATIONAL ASSOCIATION OF DENTISTRY FOR CHILDREN JAN 2008 LNKD- PUBMED:18086024, vol. 18, no. 1, January 2008 (2008-01-01), pages 35 - 39, XP002604324, ISSN: 0960-7439 *
COMELLI ELENA MARIA ET AL: "Selection of dairy bacterial strains as probiotics for oral health", EUROPEAN JOURNAL OF ORAL SCIENCES, vol. 110, no. 3, June 2002 (2002-06-01), pages 218 - 224, XP002604331, ISSN: 0909-8836 *
COSSEAU CELINE ET AL: "The commensal Streptococcus salivarius K12 downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis", September 2008, INFECTION AND IMMUNITY, VOL. 76, NR. 9, PAGE(S) 4163-4175, ISSN: 0019-9567, XP002594153 *
ELAHI S ET AL: "Enhanced clearance of Candida albicans from the oral cavities of mice following oral administration of Lactobacillus acidophilus", CLINICAL AND EXPERIMENTAL IMMUNOLOGY 200507 GB LNKD- DOI:10.1111/J.1365-2249.2005.02811.X, vol. 141, no. 1, July 2005 (2005-07-01), pages 29 - 36, XP002604333, ISSN: 0009-9104 *
HATAKKA K ET AL: "Probiotics in intestinal and non-intestinal infectious diseases - Clinical evidence", CURRENT PHARMACEUTICAL DESIGN 200805 NL LNKD- DOI:10.2174/138161208784480162, vol. 14, no. 14, May 2008 (2008-05-01), pages 1351 - 1367, XP002604334, ISSN: 1381-6128 *
HATAKKA K ET AL: "Probiotics reduce the prevalence of oral Candida in the elderly - A randomized controlled trial", JOURNAL OF DENTAL RESEARCH, vol. 86, no. 2, February 2007 (2007-02-01), pages 125 - 130, XP002604328, ISSN: 0022-0345 *
HAUKIOJA A ET AL: "Oral adhesion and survival of probiotic and other lactobacilli and bifidobacteria in vitro", ORAL MICROBIOLOGY AND IMMUNOLOGY, vol. 21, no. 5, October 2006 (2006-10-01), pages 326 - 332, XP002604327, ISSN: 0902-0055 *
KLARIN B ET AL: "Use of the probiotic Lactobacillus plantarum 299 to reduce pathogenic bacteria in the oropharynx of intubated patients: A randomised controlled open pilot study", 6 November 2008, CRITICAL CARE 20081106 GB LNKD- DOI:10.1186/CC7109, VOL. 12, NR. 6, ISSN: 1364-8535 1466-609X, XP002594142 *
KOLL P ET AL: "Characterization of oral lactobacilli as potential probiotics for oral health", April 2008, ORAL MICROBIOLOGY AND IMMUNOLOGY, VOL. 23, NR. 2, PAGE(S) 139-147, ISSN: 0902-0055, XP002594151 *
KRASSE PER ET AL: "Decreased gum bleeding and reduced gingivitis by the probiotic Lactobacillus reuteri.", SWEDISH DENTAL JOURNAL 2006 LNKD- PUBMED:16878680, vol. 30, no. 2, 2006, pages 55 - 60, XP008127657, ISSN: 0347-9994 *
MAKRAS L ET AL: "Kinetic analysis of the antibacterial activity of probiotic lactobacilli towards Salmonella enterica serovar Typhimurium reveals a role for lactic acid and other inhibitory compounds", RESEARCH IN MICROBIOLOGY, ELSEVIER, AMSTERDAM, NL LNKD- DOI:10.1016/J.RESMIC.2005.09.002, vol. 157, no. 3, 1 April 2006 (2006-04-01), pages 241 - 247, XP025101166, ISSN: 0923-2508, [retrieved on 20060401] *
MARIK PAUL E ET AL: "The role of anaerobes in patients with ventilator-associated pneumonia and aspiration pneumonia: A prospective study", January 1999, CHEST, VOL. 115, NR. 1, PAGE(S) 178-183, ISSN: 0012-3692, XP002594150 *
NIKAWA H ET AL: "Lactobacillus reuteri in bovine milk fermented decreases the oral carriage of mutans streptococci", INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, vol. 95, no. 2, 1 September 2004 (2004-09-01), pages 219 - 223, XP002604325, ISSN: 0168-1605 *
NIKAWA H ET AL: "The effect of saliva or serum on bacterial and Candida albicans colonization on type I collagen.", October 2006, JOURNAL OF ORAL REHABILITATION OCT 2006 LNKD- PUBMED:16938106, VOL. 33, NR. 10, PAGE(S) 767 - 774, ISSN: 0305-182X, XP002594152 *
NIV ET AL: "The efficacy of Lactobacillus reuteri ATCC 55730 in the treatment of patients with irritable bowel syndrome-a double blind, placebo-controlled, randomized study", CLINICAL NUTRITION, CHURCHILL LIVINGSTONE, LONDON, GB LNKD- DOI:10.1016/J.CLNU.2005.06.001, vol. 24, no. 6, 1 December 2005 (2005-12-01), pages 925 - 931, XP005177032, ISSN: 0261-5614 *
PHAM LIEN CHI ET AL: "Effects of probiotic Lactobacillus salivarius W24 on the compositional stability of oral microbial communities", 30 October 2008, ARCHIVES OF ORAL BIOLOGY, VOL. 54, NR. 2, PAGE(S) 132-137, ISSN: 0003-9969, XP002594145 *
PHILIP K ET AL: "Microbial Competition in Oral Health", INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, vol. 12, no. Suppl. 1, 22 June 2008 (2008-06-22), & 13TH INTERNATIONAL CONGRESS ON INFECTIOUS DISEASES; KUALA LUMPUR, MALAYSIA;, pages E216, XP002604326, ISSN: 1201-9712 *
POWER D A ET AL: "Preliminary investigations of the colonisation of upper respiratory tract tissues of infants using a paediatric formulation of the oral probiotic Streptococcus salivarius K12", 17 June 2008, EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES 200812 DE LNKD- DOI:10.1007/S10096-008-0569-4, VOL. 27, NR. 12, PAGE(S) 1261 - 1263, ISSN: 0934-9723, XP002594148 *
SIMARK-MATTSSON CHARLOTTE ET AL: "Lactobacillus-mediated interference of mutans streptococci in caries-free vs. caries-active subjects", EUROPEAN JOURNAL OF ORAL SCIENCES, vol. 115, no. 4, August 2007 (2007-08-01), pages 308 - 314, XP002604332, ISSN: 0909-8836 *
TEUGHELS WIM ET AL: "Probiotics and oral healthcare.", PERIODONTOLOGY 2000 2008 LNKD- PUBMED:18715361, vol. 48, 7 August 2008 (2008-08-07), pages 111 - 147, XP002594143, ISSN: 1600-0757 *
YLI-KNUUTTILA H ET AL: "Colonization of Lactobacillus rhamnosus GG in the oral cavity", ORAL MICROBIOLOGY AND IMMUNOLOGY, vol. 21, no. 2, April 2006 (2006-04-01), pages 129 - 131, XP002604330, ISSN: 0902-0055 *

Also Published As

Publication number Publication date
CA2747231A1 (fr) 2010-07-08
AU2009333388A1 (en) 2011-06-30
SG171930A1 (en) 2011-07-28
JP2012512171A (ja) 2012-05-31
ZA201105261B (en) 2012-12-27
WO2010077795A2 (fr) 2010-07-08
EP2379091A2 (fr) 2011-10-26
RU2011129693A (ru) 2013-01-27
CN102245191A (zh) 2011-11-16
BRPI0922924A2 (pt) 2017-06-06
MX2011006488A (es) 2011-07-13

Similar Documents

Publication Publication Date Title
WO2010077795A3 (fr) Compositions et méthodes pour une santé buccale améliorée
Armitage Position paper: diagnosis of periodontal diseases
WO2011056748A3 (fr) Compositions buccales destinées à traiter la sécheresse buccale
WO2007144770A3 (fr) Bactérie
WO2010068444A3 (fr) Composition de blanchiment contenant de la silice fondue
PL1673100T3 (pl) Szczepy bakterii Bifidobacterium wytwarzające kwas foliowy, preparaty i ich zastosowanie
WO2008086457A3 (fr) Compositions d'hygiène bucco-dentaire contenant un extrait d'hippophae
WO2008053444A3 (fr) Méthodes visant à traiter un trouble respiratoire au moyen d'un traitement probiotique
WO2008117266A3 (fr) Souches de bifidobacterium probiotique
ZA200805413B (en) Method for modifying gut flora in animals
PL1986669T3 (pl) Zastosowanie Bifidobacterium longum do zapobiegania i leczenia zapalenia
PT2131680E (pt) Probióticos para melhorar a microflora intestinal
WO2008128115A3 (fr) Formulations de doxépine à faible dose et procédé de préparation et d'utilisation de celle-ci
WO2009100262A3 (fr) Méthodes et systèmes de soins oraux
IL178686A (en) Preparations of bacterial strain of lactic acid and their uses
WO2011056759A3 (fr) Compositions orales pour le traitement de la sécheresse buccale
EP1812023B8 (fr) Bacteries lactiques utilisees comme souches probiotiques et compositions les contenant
SG127405A1 (en) Use of lactic acid bacteria for decreasing gum bleeding and reducing oral inflammation
PL1857507T3 (pl) Pigmenty z tlenku żelaza stabilne wobec utleniania, sposób ich wytwarzania i zastosowanie
PL1857506T3 (pl) Stabilne oksydacyjnie pigmenty tlenku żelaza, sposób ich wytwarzania i ich zastosowanie
FR2908042B1 (fr) Ensemble d'intubation monocanaliculonasal et/ou monocanaliculaire,notamment pour l'imperforation lacrymonasale.
DK1880727T3 (da) Topisk vaginal farmaceutiske sammensætninger
WO2009059054A3 (fr) Souches de bactéries et bactériocine produite à partir de celles-ci
WO2009102939A3 (fr) Produit de soins oraux d’animaux de compagnie et procédé
AP2409A (en) Novel enterococcus and streptococcus strains and bacteriocins.

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200980150395.0

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09793395

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 12011501081

Country of ref document: PH

WWE Wipo information: entry into national phase

Ref document number: 4247/DELNP/2011

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2011540944

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2747231

Country of ref document: CA

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: MX/A/2011/006488

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 2009793395

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2009333388

Country of ref document: AU

Date of ref document: 20091214

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 13139787

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2011129693

Country of ref document: RU

REG Reference to national code

Ref country code: BR

Ref legal event code: B01E

Ref document number: PI0922924

Country of ref document: BR

ENP Entry into the national phase

Ref document number: PI0922924

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20110614