WO2011004387A3 - Procédé de préparation de formes polymorphes du dexlansoprazole - Google Patents

Procédé de préparation de formes polymorphes du dexlansoprazole Download PDF

Info

Publication number
WO2011004387A3
WO2011004387A3 PCT/IN2010/000415 IN2010000415W WO2011004387A3 WO 2011004387 A3 WO2011004387 A3 WO 2011004387A3 IN 2010000415 W IN2010000415 W IN 2010000415W WO 2011004387 A3 WO2011004387 A3 WO 2011004387A3
Authority
WO
WIPO (PCT)
Prior art keywords
dexlansoprazole
preparation
polymorphic forms
amorphous
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2010/000415
Other languages
English (en)
Other versions
WO2011004387A2 (fr
Inventor
Ramakoteswara Rao Jetti
Neelima Bhagavatula
Saswata Lahiri
Lakshmana Rao Vadali
Swamy Saidugari
Veera Narayana Bandlamudi
Shankar Rama
Seshardi Rao Manukonda
Srinivasa Rao P. V.
Debashish Datta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mylan Laboratories Ltd
Original Assignee
Matrix Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matrix Laboratories Ltd filed Critical Matrix Laboratories Ltd
Publication of WO2011004387A2 publication Critical patent/WO2011004387A2/fr
Publication of WO2011004387A3 publication Critical patent/WO2011004387A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne un nouveau procédé de préparation de dexlansoprazole amorphe à partir d'un solvate de dexlansoprazole. La présente invention concerne également de nouveaux procédés de préparation des formes polymorphes IV, VI et des formes amorphes, anhydres et semi-hydratées du dexlansoprazole.
PCT/IN2010/000415 2009-06-18 2010-06-17 Procédé de préparation de formes polymorphes du dexlansoprazole Ceased WO2011004387A2 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IN1436/CHE/2009 2009-06-18
IN1436CH2009 2009-06-18
IN2408/CHE/2009 2009-10-05
IN2408CH2009 2009-10-05
IN0359/CHE/2010 2010-02-15
IN359CH2010 2010-02-15

Publications (2)

Publication Number Publication Date
WO2011004387A2 WO2011004387A2 (fr) 2011-01-13
WO2011004387A3 true WO2011004387A3 (fr) 2011-06-23

Family

ID=43218704

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2010/000415 Ceased WO2011004387A2 (fr) 2009-06-18 2010-06-17 Procédé de préparation de formes polymorphes du dexlansoprazole

Country Status (1)

Country Link
WO (1) WO2011004387A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1395118B1 (it) 2009-07-29 2012-09-05 Dipharma Francis Srl Procedimento per la preparazione di dexlansoprazolo cristallino
AU2012274967A1 (en) * 2011-06-21 2014-01-23 Sun Pharmaceutical Industries Limited Process for the preparation of dexlansoprazole
CN105017216A (zh) * 2014-04-16 2015-11-04 天津药物研究院 右兰索拉唑晶型iii及其制备方法和用途
WO2015171723A1 (fr) 2014-05-06 2015-11-12 Research Development Foundation Méthodes pour traiter la résistance à l'insuline et pour sensibiliser des patients à un traitement avec un agoniste du glp1
CN105017218A (zh) * 2015-07-01 2015-11-04 合肥安德生制药有限公司 一种右兰索拉唑晶型及其制备方法
IT201700050223A1 (it) * 2017-05-09 2018-11-09 Dipharma Francis Srl Procedimento per la preparazione di dexlansoprazolo cristallino
WO2024153744A1 (fr) 2023-01-20 2024-07-25 Institut National de la Santé et de la Recherche Médicale Activateurs d'autophagie pour le traitement de la rhabdomyolyse

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998021201A1 (fr) * 1996-11-14 1998-05-22 Takeda Chemical Industries, Ltd. Cristaux de derives benzimidazole et leur production
WO2002044167A1 (fr) * 2000-12-01 2002-06-06 Takeda Chemical Industries, Ltd. Procede de cristallisation du (r)- ou du (s)-lansoprazole
WO2003082857A2 (fr) * 2002-03-27 2003-10-09 Teva Pharmaceutical Industries Ltd. Polymorphes de lansoprazole et procedes de preparation de ces derniers
WO2004083200A1 (fr) * 1999-06-17 2004-09-30 Akira Fujishima Forme cristalline de (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole
EP1552833A1 (fr) * 2002-10-16 2005-07-13 Takeda Chemical Industries, Ltd. Preparations solides stables
WO2009117489A1 (fr) * 2008-03-18 2009-09-24 Dr. Reddy's Laboratories Ltd. Procédé de préparation du dexlansoprazole et autres formes polymorphes
EP2216333A2 (fr) * 2009-02-06 2010-08-11 Dipharma Francis S.r.l. Formules cristallines de dexlansoprazole
WO2010104314A2 (fr) * 2009-03-09 2010-09-16 한미약품 주식회사 Procédé de préparation de (+)-lansoprazole non cristallin et alcoolate de (+)-lansoprazole utilisé dans ce procédé

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
DE4035455A1 (de) 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
HRP960232A2 (en) 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
JP3828648B2 (ja) 1996-11-14 2006-10-04 武田薬品工業株式会社 ２−（２−ピリジルメチルスルフィニル）ベンズイミダゾール系化合物の結晶およびその製造法
WO1999038513A1 (fr) 1998-01-30 1999-08-05 Sepracor Inc. Compositions et procedes d'utilisation du r-lansoprazole
DE60131649T2 (de) 2000-05-15 2008-10-30 Takeda Pharmaceutical Co. Ltd. Verfahren zur herstellung eines kristalls
JP5412023B2 (ja) 2000-08-04 2014-02-12 武田薬品工業株式会社 ベンズイミダゾール化合物の塩およびその用途
US20100280077A1 (en) 2007-12-18 2010-11-04 Watson Pharma Private Limited Process for Preparation of Stable Amorphous R-Lansoprazole
JP2011507977A (ja) 2007-12-31 2011-03-10 武田薬品工業株式会社 （ｒ）−２−［［［３−メチル−４−（２，２，２−トリフルオロエトキシ）−２−ピリジニル］メチル］スルフィニル］−１ｈ−ベンズイミダゾールの溶媒和物結晶形
EA017064B1 (ru) 2008-03-10 2012-09-28 Такеда Фармасьютикал Компани Лимитед Кристаллическое производное бензимидазола

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998021201A1 (fr) * 1996-11-14 1998-05-22 Takeda Chemical Industries, Ltd. Cristaux de derives benzimidazole et leur production
WO2004083200A1 (fr) * 1999-06-17 2004-09-30 Akira Fujishima Forme cristalline de (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole
WO2002044167A1 (fr) * 2000-12-01 2002-06-06 Takeda Chemical Industries, Ltd. Procede de cristallisation du (r)- ou du (s)-lansoprazole
WO2003082857A2 (fr) * 2002-03-27 2003-10-09 Teva Pharmaceutical Industries Ltd. Polymorphes de lansoprazole et procedes de preparation de ces derniers
EP1552833A1 (fr) * 2002-10-16 2005-07-13 Takeda Chemical Industries, Ltd. Preparations solides stables
WO2009117489A1 (fr) * 2008-03-18 2009-09-24 Dr. Reddy's Laboratories Ltd. Procédé de préparation du dexlansoprazole et autres formes polymorphes
EP2216333A2 (fr) * 2009-02-06 2010-08-11 Dipharma Francis S.r.l. Formules cristallines de dexlansoprazole
WO2010104314A2 (fr) * 2009-03-09 2010-09-16 한미약품 주식회사 Procédé de préparation de (+)-lansoprazole non cristallin et alcoolate de (+)-lansoprazole utilisé dans ce procédé

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2010, JANG, SUN YOUNG ET AL: "Method for preparing non- crystalline (+)-lansoprazole and (+)-lansoprazole alcoholate used in same", XP002614116, retrieved from STN Database accession no. 2010:1161381 *

Also Published As

Publication number Publication date
WO2011004387A2 (fr) 2011-01-13

Similar Documents

Publication Publication Date Title
WO2011039108A3 (fr) Procédés de préparation de dérivés de benzyl-benzène substitués par un glucopyranosyle
WO2011004387A3 (fr) Procédé de préparation de formes polymorphes du dexlansoprazole
WO2011022596A3 (fr) Préparation de bazédoxifène et de ses sels
WO2010139981A3 (fr) Procédés d'élaboration de formes cristallines
WO2012015999A3 (fr) Procédé de préparation de mésylate d'imatinib
WO2011024192A3 (fr) Nouveaux polymorphes du raltegravir
WO2010076810A3 (fr) Procédé d'élaboration de géfitinibe
EP2280039B8 (fr) Procédé de production d un composé de polysilane
WO2011015882A3 (fr) Nouvel anhydrate
WO2011015287A3 (fr) Procédé pour la préparation de dérivés d'acide 1-(2-halogénobiphényl-4-yl)-cyclopropanecarboxylique
WO2010123545A3 (fr) Inhibiteurs de l'angiogenèse
MX2011009898A (es) Proceso para la obtencion de derivados de acido propionico.
WO2010004578A3 (fr) Nouveaux procédés améliorés de préparation de la palipéridone
UA106988C2 (uk) Спосіб одержання 1-бензил-3-гідроксиметил-1h-індазолу і його похідних та необхідні проміжні сполуки магнію
WO2010121877A3 (fr) Procédé de préparation de l'olopatadine
MX2012002818A (es) Nuevo procedimiento de sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable.
WO2010083996A8 (fr) Procédé de synthèse de la mémantine
WO2011018771A3 (fr) Procédé de préparation de chlorhydrate de valganciclovir
WO2014087208A3 (fr) Procédé de préparation d'alcaftadine
WO2011058524A3 (fr) Formes cristallines du sel de bosentan et leurs procédés de préparation
WO2009060297A3 (fr) Procédé perfectionné pour la préparation de la palipéridone et de ses intermédiaires
WO2009147626A3 (fr) Forme amorphe anhydre de imatinib mesylate
WO2010146595A3 (fr) Nouveaux polymorphes d'hydrochlorure de flibansérine
WO2011100282A3 (fr) Polymorphes de mésylate d'imatinib
TN2012000154A1 (en) Process for the manufacture of organic compounds

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10768081

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10768081

Country of ref document: EP

Kind code of ref document: A2