WO2012120532A3 - Cyclic short chain pth analog peptides - Google Patents

Cyclic short chain pth analog peptides Download PDF

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Publication number
WO2012120532A3
WO2012120532A3 PCT/IN2012/000078 IN2012000078W WO2012120532A3 WO 2012120532 A3 WO2012120532 A3 WO 2012120532A3 IN 2012000078 W IN2012000078 W IN 2012000078W WO 2012120532 A3 WO2012120532 A3 WO 2012120532A3
Authority
WO
WIPO (PCT)
Prior art keywords
short chain
analog peptides
pth analog
cyclic
cyclic short
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2012/000078
Other languages
French (fr)
Other versions
WO2012120532A2 (en
Inventor
Rajesh H Bahekar
Vjay PRAJAPATI
Mukul R. Jain
Pankaj R. Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zydus Lifesciences Ltd
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Publication of WO2012120532A2 publication Critical patent/WO2012120532A2/en
Publication of WO2012120532A3 publication Critical patent/WO2012120532A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention provides novel cyclic short-chain peptideshaving pharmaceutically beneficial properties. The invention also provides a process for preparing such short chain peptides and pharmaceutical compositions containing the cyclic peptides of the present invention. A-Z 1-Z2-Z3-Z4-Z5-Z6-Z7-Z8-Z9-Z10-Z11-Z 12-Z13-Z 14-Z 15-B (I)
PCT/IN2012/000078 2011-02-02 2012-02-02 Cyclic short chain peptides Ceased WO2012120532A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN301MU2011 2011-02-02
IN301/MUM/2011 2011-02-02

Publications (2)

Publication Number Publication Date
WO2012120532A2 WO2012120532A2 (en) 2012-09-13
WO2012120532A3 true WO2012120532A3 (en) 2013-03-14

Family

ID=46579272

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2012/000078 Ceased WO2012120532A2 (en) 2011-02-02 2012-02-02 Cyclic short chain peptides

Country Status (1)

Country Link
WO (1) WO2012120532A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113736741A (en) * 2021-08-18 2021-12-03 上海市食品药品检验研究院 A cloned cell line for determining the biological activity of teriparatide
CN115925802B (en) * 2023-02-22 2024-07-23 西南交通大学 Antibacterial peptide with enhanced antibacterial activity and serum stability and application thereof
WO2025250872A1 (en) * 2024-05-31 2025-12-04 Florida Atlantic University Board Of Trustees Antibody complementary determining region of heavy chain 3 mimics and methods of use thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004067021A1 (en) * 2003-01-24 2004-08-12 Gardella Thomas J Conformationally constrained parathyroid hormone (pth) analogs with lactam bridges
WO2008068487A1 (en) * 2006-12-08 2008-06-12 Zealand Pharma A/S Truncated pth peptides with a cyclic conformation
WO2010128521A2 (en) * 2009-04-24 2010-11-11 Cadila Healthcare Limited Short-chain peptides as parathyroid hormone (pth) receptor agonist

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1447600A (en) 1998-10-22 2000-05-08 Thomas J. Gardella Bioactive peptides and peptide derivatives of parathyroid hormone (pth) and parathyroid hormone-related peptide (pthrp)
CA2454275C (en) 2001-07-23 2012-10-23 The General Hospital Corporation Conformationally constrained parathyroid hormone (pth) analogs
AU2002951372A0 (en) 2002-09-13 2002-09-26 St Vincent's Institute Of Medical Research Parathyroid hormone-like polypeptides
US7795220B2 (en) 2003-03-19 2010-09-14 The General Hospital Corporation Conformationally constrained parathyroid hormones with alpha-helix stabilizers
WO2005009358A2 (en) 2003-07-17 2005-02-03 The General Hospital Corporation Conformationally constrained parathyroid hormone (pth) analogs
WO2005077918A1 (en) 2004-02-11 2005-08-25 Smithkline Beecham Corporation Pth agonists
WO2005077959A1 (en) 2004-02-11 2005-08-25 Smithkline Beecham Corporation Pth agonists
ITMI20041440A1 (en) 2004-07-19 2004-10-19 Abiogen Pharma Spa ANALOGUE PEPTIDES OF PTH-1-11
WO2007130113A2 (en) 2005-09-06 2007-11-15 Zelos Therapeutics, Inc. Parathyroid hormone analogues and methods of use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004067021A1 (en) * 2003-01-24 2004-08-12 Gardella Thomas J Conformationally constrained parathyroid hormone (pth) analogs with lactam bridges
WO2008068487A1 (en) * 2006-12-08 2008-06-12 Zealand Pharma A/S Truncated pth peptides with a cyclic conformation
WO2010128521A2 (en) * 2009-04-24 2010-11-11 Cadila Healthcare Limited Short-chain peptides as parathyroid hormone (pth) receptor agonist

Also Published As

Publication number Publication date
WO2012120532A2 (en) 2012-09-13

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