WO2012120532A3 - Peptides cycliques à chaîne courte - Google Patents

Peptides cycliques à chaîne courte Download PDF

Info

Publication number
WO2012120532A3
WO2012120532A3 PCT/IN2012/000078 IN2012000078W WO2012120532A3 WO 2012120532 A3 WO2012120532 A3 WO 2012120532A3 IN 2012000078 W IN2012000078 W IN 2012000078W WO 2012120532 A3 WO2012120532 A3 WO 2012120532A3
Authority
WO
WIPO (PCT)
Prior art keywords
short chain
analog peptides
pth analog
cyclic
cyclic short
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2012/000078
Other languages
English (en)
Other versions
WO2012120532A2 (fr
Inventor
Rajesh H Bahekar
Vjay PRAJAPATI
Mukul R. Jain
Pankaj R. Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zydus Lifesciences Ltd
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Publication of WO2012120532A2 publication Critical patent/WO2012120532A2/fr
Publication of WO2012120532A3 publication Critical patent/WO2012120532A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne de nouveaux peptides cycliques à chaîne courte présentant des propriétés pharmaceutiques bénéfiques. L'invention concerne aussi un procédé de préparation de tels peptides à chaîne courte et des compositions phamaceutiques renfermant les peptides cycliques de la présente invention. A-Z 1-Z2-Z3-Z4-Z5-Z6-Z7-Z8-Z9-Z10-Z11-Z 12-Z13-Z 14-Z 15-B (I)
PCT/IN2012/000078 2011-02-02 2012-02-02 Peptides cycliques à chaîne courte Ceased WO2012120532A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN301MU2011 2011-02-02
IN301/MUM/2011 2011-02-02

Publications (2)

Publication Number Publication Date
WO2012120532A2 WO2012120532A2 (fr) 2012-09-13
WO2012120532A3 true WO2012120532A3 (fr) 2013-03-14

Family

ID=46579272

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2012/000078 Ceased WO2012120532A2 (fr) 2011-02-02 2012-02-02 Peptides cycliques à chaîne courte

Country Status (1)

Country Link
WO (1) WO2012120532A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113736741A (zh) * 2021-08-18 2021-12-03 上海市食品药品检验研究院 一种用于测定特立帕肽生物学活性的克隆化细胞株
CN115925802B (zh) * 2023-02-22 2024-07-23 西南交通大学 一种具有增强抗菌活性和血清稳定性的抗菌肽及其应用
WO2025250872A1 (fr) * 2024-05-31 2025-12-04 Florida Atlantic University Board Of Trustees Région de détermination complémentaire d'anticorps de mimétiques de chaîne lourde 3 et ses procédés d'utilisation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004067021A1 (fr) * 2003-01-24 2004-08-12 Gardella Thomas J Analogues de parathormone (pth) a contrainte conformationnelle avec ponts lactame
WO2008068487A1 (fr) * 2006-12-08 2008-06-12 Zealand Pharma A/S Peptides pth tronqués à configuration cyclique
WO2010128521A2 (fr) * 2009-04-24 2010-11-11 Cadila Healthcare Limited Peptides à chaîne courte comme agoniste du récepteur de l'hormone parathyroïdienne (pth)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1123401A1 (fr) 1998-10-22 2001-08-16 The General Hospital Corporation PEPTIDES ET DERIVES PEPTIDIQUES BIOACTIFS DE L'HORMONE PARATHYROIDE (PTH) ET DE LA PROTEINE LIEE A L'HORMONE PARATHYROIDE (PTHrP)
AU2002339843B2 (en) 2001-07-23 2007-12-06 The General Hospital Corporation Conformationally constrained parathyroid hormone (PTH) analogs
AU2002951372A0 (en) 2002-09-13 2002-09-26 St Vincent's Institute Of Medical Research Parathyroid hormone-like polypeptides
AU2003220380A1 (en) 2003-03-19 2004-11-19 Bristol-Myers Squibb Company CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH Alpha-HELIX STABILIZERS
JP4871128B2 (ja) 2003-07-17 2012-02-08 ザ ジェネラル ホスピタル コーポレイション 高次構造的に制約された副甲状腺ホルモン（ｐｔｈ）アナログ
WO2005077918A1 (fr) 2004-02-11 2005-08-25 Smithkline Beecham Corporation Agonistes de pth
US20070099940A1 (en) 2004-02-11 2007-05-03 Spearing Paul K Pth agonists
ITMI20041440A1 (it) 2004-07-19 2004-10-19 Abiogen Pharma Spa Peptidi analoghi del pth-1-11
CA2621264A1 (fr) 2005-09-06 2007-11-15 Zelos Therapeutics, Inc. Analogues de l'hormone parathyroidienne et procedes les utilisant

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004067021A1 (fr) * 2003-01-24 2004-08-12 Gardella Thomas J Analogues de parathormone (pth) a contrainte conformationnelle avec ponts lactame
WO2008068487A1 (fr) * 2006-12-08 2008-06-12 Zealand Pharma A/S Peptides pth tronqués à configuration cyclique
WO2010128521A2 (fr) * 2009-04-24 2010-11-11 Cadila Healthcare Limited Peptides à chaîne courte comme agoniste du récepteur de l'hormone parathyroïdienne (pth)

Also Published As

Publication number Publication date
WO2012120532A2 (fr) 2012-09-13

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