WO2012165831A2 - Composition aromatique ayant des effets anti-stress et relaxants et composition cosmétique la contenant - Google Patents

Composition aromatique ayant des effets anti-stress et relaxants et composition cosmétique la contenant Download PDF

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Publication number
WO2012165831A2
WO2012165831A2 PCT/KR2012/004212 KR2012004212W WO2012165831A2 WO 2012165831 A2 WO2012165831 A2 WO 2012165831A2 KR 2012004212 W KR2012004212 W KR 2012004212W WO 2012165831 A2 WO2012165831 A2 WO 2012165831A2
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WO
WIPO (PCT)
Prior art keywords
oil
composition
weight
fragrance
cream
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Ceased
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PCT/KR2012/004212
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English (en)
Korean (ko)
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WO2012165831A3 (fr
Inventor
이은주
서형제
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Amorepacific Corp
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Amorepacific Corp
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Priority to CN201280025673.1A priority Critical patent/CN103619322B/zh
Publication of WO2012165831A2 publication Critical patent/WO2012165831A2/fr
Publication of WO2012165831A3 publication Critical patent/WO2012165831A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Definitions

  • the present invention relates to a perfume composition and a cosmetic composition having a stress relief and soothing effect.
  • Stress is a psychological / physical state of tension when faced with difficult conditions. Long-term stress can lead to physical illnesses such as heart disease, gastric ulcers and hypertension, and psychological negatives such as insomnia, neurosis and depression. In an industrial society in which conflicts and competition are fierce, as the society changes structurally and functionally, most of the modern people who have to respond to it face a lot of physical and psychological stress. Proper stress can also be a vital energy source for life because it drives life, increases efficiency and productivity. However, stress can be an important health risk factor because excessive stress can lead to illness or death. Therefore, awareness of and management of stress is essential for maintaining and promoting health.
  • An object of the present invention is to provide a perfume composition and a cosmetic composition that alleviate stress and have a physiological and psychological therapeutic effect. .
  • the present invention is an active ingredient selected from the group consisting of Patchouli oil (Patchouli oil), Ptankin sense oil (Frankincense) and Sandalwood oil (Sandalwood oil) It provides a fragrance composition containing.
  • this invention provides the cosmetic composition containing the said fragrance composition.
  • the perfume composition according to the present invention has a physiological and psychological therapeutic effect, has a stress relaxation, tension relaxation, relaxation, emotional stability, relaxation effect, and can be used in various fields such as beauty and cosmetics.
  • Figure 1 is a relative alpha wave according to the use of the perfume composition of an embodiment of the present invention
  • Figure 2 is a map of the brain waves according to the use of the perfume composition of an embodiment of the present invention
  • Figure 3 is a relative beta wave according to the use of the fragrance composition of one embodiment of the present invention.
  • FIG. 4 shows the heart rate change rate by measuring the average heart rate interval (RRI) after the use of the perfume composition of an embodiment of the present invention.
  • Figure 5 shows the activity ratio (LF / HF value) of the sympathetic nerve to the parasympathetic nerve of the heart after using the perfume composition of an embodiment of the present invention.
  • FIG. 6 shows a comparison result of the average skin electroresistance for 1 minute using the perfume composition of one embodiment of the present invention.
  • FIG. ' shows a comparison result of the average skin electroresistance for 1 minute using the perfume composition of one embodiment of the present invention.
  • One embodiment of the present invention is a patchouli oil (Patchouli oil), Ptankin sense oil
  • It provides a fragrance composition containing at least one natural oil selected from the group consisting of Frankincense oil and Sandalwood oil as an active ingredient.
  • the fragrance composition is fine oil (Pine oil), Mandarin oil (Mandarine oil), Bergamot oil (Bergamot oil), Orange oil (Orange oil), Lavender oil (Lavender oil), Clove oil, Lemongrass oil oil) and geranium oil may further contain one or more natural oils selected from the group consisting of:
  • the fragrance composition is patchouli oil, Franklinsense oil, sandalwood oil, pine oil, mandarin oil, bergamot oil, orange oil, lavender oil, clove oil, lemongrass oil and Geranium. May contain oil.
  • Patchouli oil is a dark brown liquid obtained by distillation of lamiaceae and evergreen shrub (/ os a! 70/2 cabUn)
  • ⁇ is a sweet aromatic essential oil of dark wood. It has long been used for deodorization and insect repellent treatment, and has anti-inflammatory, anti-allergic and bactericidal effect. It is also effective in relieving stress, such as reducing depression and anxiety.
  • Ptankinsense oil is a brownish, viscous liquid derived from olive tree carterii (birdwood), a resin-based essential oil with a fresh, sweet flavor. It is effective in stabilizing breathing, disinfecting and disinfecting bronchial system, improving asthma, inducing comfortable sleep, reducing tension, reducing anxiety and stress, and used as a fragrance for cosmetics, perfumes, drinks and food.
  • Sandalwood oil is a light brown liquid obtained by distilling dandelion and sandalwood (532 3 / ⁇ 77 Album). It is a woody essential oil with a mild wood scent. It has anti-inflammatory and antiseptic effect and moisturizes dry skin. It also helps relieve anxiety and tension and is effective for a good night's sleep.
  • Pine oil is a generic term for oil extracted from the leaves of pine 0 ° / 2i / s Palustris or Abies Siberica, also called pine needle fragrance oil.
  • leaf (coniferous) sites can be extracted via steam distillation.
  • Reticulata is a fresh, flaky oil from skin. In France, it has been used to treat children's digestive disorders and hiccups, and it is effective for skin softening, wound recovery, sterilization, fat reduction, anti-depression, diversion, and relaxation.
  • Bergamot is an evergreen tree (Y n / s) with dicotyledonous rats.
  • Bergamia ⁇ , cultivated in Europe for fragrance and essential oils, also planted for ornamental purposes.
  • Bergamot oil is a general term for the fragrance oil obtained from the skin of bergamot.
  • Bergamot oil is a colorless liquid with a fresh, tangy scent of citrus-based oil, which helps to stabilize the mind, help breathing, and release tension muscles caused by mental stress.
  • Orange oil is an evergreen tree with dicotyledonous rats. ⁇ Citrus Oil extracted from the rind gives a sweet and warm citrus flavor. Orange oil is known to relieve hysteria, mental strain, fatigue and relieve depression, and to help skin cells regenerate and remove toxins.
  • Lavender is a perennial ALavandula Officinalis belonging to the dicotyledons Lavendera and Lavandula. It is purple or purple and has a refreshing and light herb all over the abandonment.
  • Lavender oil which is obtained by extracting or steam distilling lavender lavender, is known to be effective in activating skin cells, stratum corneum, disinfecting, restoring fatigue, reducing tension, and insomnia.
  • Clove oil is dicotyledonous plated cactus clove ( ⁇ i ⁇ /
  • Caryophyllata ⁇ ⁇ The pale yellow oil that is extracted and has a strong, spicy aroma. It can be used as a spice in foods, or as a painkiller in dentistry. It is also known to be effective against antibacterial, antioxidant, antiseptic and anxious emotions.
  • Lemongrass is a perennial with cypresses. Cymbopogon — lemon scents throughout the plant. Oils from leaves and roots are known to relieve stress and mental fatigue, insomnia and depression, as well as analgesic and antibacterial effects.
  • Geranium is a perennial genus of rats and grasshoppers ⁇ ⁇ Pelargonium
  • GraveoJens has a rose-like scent throughout the plant and extracts oil from leaves and branches. Geranium oil is known to relieve respiratory disease and reduce stress.
  • the fragrance composition based on the total weight of the composition, 0.1-20% by weight of patchouli oil, 1-50% by weight of Ptankin sense oil, 1-50% by weight of sandalwood oil , 1-50% by weight of fine oil, 1-50% by weight of mandarin oil, 1-50% by weight of bergamot oil, 1-50% by weight of orange oil, 1-50% by weight of lavender oil, 0.1-10% by weight of clove oil , Lemon Glass oil may contain 0.1 to 10% by weight and geranium oil to 0.1 to 10% by weight.
  • the composition ratio of the fragrance composition is to take into consideration the effect of emotional stability and at the same time, considering the user's preference through the harmony of the fragrance of each component, if the ratio of the essential oil is out of the above range, the specific fragrance becomes stronger Therefore, it is preferable not to deviate from the above range because the palatability may deteriorate due to a burden that is not suitable for the user's taste.
  • the fragrance S property may increase alpha waves in brain waves and reduce beta waves. In EEG, alpha ( ⁇ ) waves are at rest, beta ( ⁇ ) waves are unstable or nervous, theta waves are pleasant or sleepy, and delta waves occur at deep sleep.
  • the increase in the activity ratio of the alpha wave means that it has a relaxing and calming effect on the human body and makes people feel comfortable.
  • the composition can be used as a composition for relaxation, relaxation, emotional stability and relaxation.
  • the perfume composition of the present invention can reduce the sympathetic nerve activity.
  • the composition may be a composition for stress relief.
  • the perfume composition of the present invention can increase the average heart rate (RRI) when measuring the rate of change in heart rate.
  • the perfume composition may reduce the skin electrical resistance value.
  • the perfume composition may be a composition for physiological and psychological treatment
  • An embodiment of the present invention provides a cosmetic composition containing the perfume composition.
  • the fragrance composition may be contained in an amount of 0.001 to 10 weight 3 ⁇ 4>, specifically, 0.01 to 1.0 weight% based on the total weight of the cosmetic composition. If the content of the fragrance composition is less than 0.001% by weight, it is difficult to expect the effect, and when the content exceeds 10% by weight, the strength may be so strong that the palatability for odor may not be good.
  • the content of the perfume composition can be adjusted within the above range according to the characteristics of the cosmetic composition.
  • the formulation of the cosmetic composition for example, supple cosmetics, astringent cosmetics, nourishing cosmetics, nutrition lotion, nutrition essence, nutrition cream, massage cream, essence, eye cream eye essence, Cleansing cream, cleansing product, cleansing water, pack, gel, powder, makeup base, body lotion, body cream, body oil, body essence, lotion, ointment, gel, cream, patch and spray Can be.
  • a patchouli oil (Example 1)
  • a combination fragrance (Example 2)
  • a Frankensense oil (Example 3)
  • a sandalwood oil (Example 4)
  • the fragrance composition is provided, and the physiological signals such as EEG of the central nervous system, average heart rate (average RR interval) of the autonomic nervous system, skin electrical resistance, etc. was measured.
  • the specific method is as follows.
  • Subject is in their twenties, healthy, not currently taking medication, and not blind
  • the subjects were 20 women in their 30s. Restrictions on excessive exercise and excessive alcohol intake on the day before the experiment may affect the central nervous system and sense of smell. Refrain from smoking, drinks, drugs, and chewing gum. This study was conducted in adult women, and it was reported that there is a correlation between women's menstrual cycle and mood change.
  • Experimental samples include patchouli oil (excitation) (example 1), combination fragrance (example 2), frucchinense oil (incense) (example 3), sandalwood oil (sandalwood) (example 4) ), The control group In Comparative Example 1, no incense was used. The physiological response was measured while subjects smelled the fragrance provided in the experiment.
  • the patchouli oil is obtained by steam distillation of dried grass and evergreen shrub (/ 3 ⁇ 4gos e / z? I cabling].
  • the extract is steam distilled or extracted by steam distillation of resin obtained from the olive oil of olive oil family.
  • the oil obtained was used, and sandalwood oil was prepared by steam distillation of fennel and sandalwood, and a combination scent was prepared by mixing natural flavor oils according to the composition ratios of Table 1 above.
  • the experiment was carried out in the olfactory laboratory (4.8 mX3 mX2.4 m), and inside the intake and exhaust facilities for the purpose of reducing the smell of olfactory, and the subject's participation ' maximize the participation and the influence of the external environment during the experiment. Sound insulation is installed to rule out.
  • the internal temperature (25 ° C), humidity (40-50) and roughness (150-200 Lx) were kept constant during the experiment. After the experiment was completed for one condition, the subject was rested sufficiently so that there was no influence on odor and fatigue on the fragrance, and the experiment was performed after ventilating the inside of the laboratory.
  • EEG putting the frontal parietal lobe, an electrode for brain wave measurement on the temporal lobe, occipital lobe portion (GRASS, USA) according to the International 10-20 electrode batch method using a GRASS (USA) equipment, MP system 100 (USA), Program Acknowledge (USA) Measured.
  • the resistance value between each measurement site was set to 10 kQ or less, and the sampling rate was set to 512 Hz.
  • Electrocardiogram was performed by attaching an electrocardiogram electrode to the chest, and galvanic skin response was measured by attaching a sensor to the left hand middle finger and ring finger.
  • Physiological signals were measured using MP 100 system / Acknowledge program and the sampling rate was set to 512 Hz.
  • EEG was analyzed by the power spectrum by FFT method, and then ⁇ / ( ⁇ + ⁇ + ⁇ + ⁇ ) and ⁇ / ( ⁇ + ⁇ + ⁇ + ⁇ ) 1- were calculated according to the frequency band.
  • HRV Heart rate change rate
  • HRV Heart rate change rate
  • LF Low frequency: 0.04-0.08 Hz
  • HF High frequency: 0.15-0.4 Hz
  • GSR Skin electrical resistance
  • the physiological signal analysis values according to the experimental conditions were obtained from the mean and standard deviation. Statistical analysis was performed using the SPSS program and AN-VA analysis and t-test for each perfume. The correlation was verified by Pearson correlation analysis.
  • Patchouli oil, Ptankinsens oil, sandalwood oil and combination fragrances showed a higher rate of alpha waves during calm / relaxation than none provided.
  • the ratio of relative alpha waves increased the most when the combination fragrance was provided.
  • EEG which appears when a person sells Alpha relaxed state will accepting comfortable it toward a subject is presented that increases its rate, and incense that alfalfa increased activation is that the feel is complete and calm, comfortable to humans .
  • the combination fragrance that showed the highest alpha wave ratio has the most relaxing effect.
  • Figure 2 shows the mapping of the brain waves according to the use of the fragrance composition of the present invention (mapping).
  • Alpha wave activity is more active when the fragrance is provided than when the fragrance is not provided.
  • alpha wave activity was higher in all brain regions including the occipital lobe than in other fragrance conditions.
  • Example 4 using sandalwood oil (sandalwood)
  • similar mapping as in Example 3 was observed, but at 12.5 seconds treatment, red mapping was more excessively observed in the occipital lobe.
  • Example 2 using the combination fragrance, the most predominant red color mapping was observed in the whole range of the brain, especially the occipital lobe, 2.5 seconds after the combination fragrance treatment. It was built.
  • Beta wave is an electroencephalogram that appears when anxious or nervous. A high rate indicates that the subject is in an elongated or awake state. In other words, the fact that the beta wave ratio was lower than when none of the above was suggested suggests that each of the fragrances has a relaxing effect.
  • Heart rate change rate refers to the high frequency of heart rate and was measured by the average heart rate (average RR interval: RRI) in this experiment (Fig. 4). Comparing the average heart rate (mean RR interval) for 1 minute when fragrance was provided, the heart rate interval was wider in patchouli oil, Ptankin sense oil, sandalwood oil and combination fragrance conditions than when nothing was presented. When the tension increases, the heart rate becomes narrower, and when relaxing, the heart rate becomes smaller and the heart rate becomes wider. In other words, increasing average RR intervals means Running slowly means feeling comfortable and secure.
  • the activity ratio (LF / HF) of the sympathetic nerve to the parasympathetic nerve of the heart is shown in FIG. 5.
  • the ratio of sympathetic activity (LF / HF) to the parasympathetic nerve of the heart is the ratio of sympathetic and parasympathetic nerves, which is proportional to sympathetic nerve activity and inversely proportional to sympathetic nerve activity.
  • the activity ratio of sympathetic and parasympathetic nerves (LF / HF) was significantly decreased in patchouli oil, ptankinsen oil, sandalwood oil and combination fragrance conditions when nothing was presented.
  • the low activity ratio (LF / HF) of the sympathetic and parasympathetic nerves of the heart means that the activity of the sympathetic nerves is low, which means that the brain is in a stable state. In other words, brain activity is stabilized in patchouli oil, ptankin sense oil, sandalwood oil and combination fragrance conditions rather than nothing.
  • the electrical resistance of skin refers to the change over time and the average amplitude value (potential difference) of the waveform. When the tension is relaxed, the amplitude value becomes large and when relaxed, the amplitude value becomes small.
  • the average skin electrical resistance value was reduced when Patchouli oil, Frampkinsense oil, Sandalwood oil and Combination fragrance were provided compared to when nothing was presented. Patchouli oil, ptankin sense oil, sandalwood oil, and combination fragrances have lower skin electrical resistance values than when none were presented, which may help to relax and stabilize the skin.
  • the nourishing cream containing the composition of Example 2 was prepared according to a conventional method as shown in Table 4 below. ⁇
  • a pack containing the composition of Example 2 was prepared according to a conventional method as shown in Table 6 below.
  • Cosmetic preparations were prepared according to conventional methods.
  • Example 9 As shown in Table 9 below, two cakes and powder cosmetics containing the composition of Example 2 were prepared according to a conventional method.
  • the fragrance composition according to the present invention has a physiological and psychological therapeutic effect, has a stress relaxation, tension relaxation, relaxation, emotional stability, relaxation effect, and can be used in various fields such as beauty and cosmetics.

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Abstract

La présente invention concerne une composition aromatique et une composition cosmétique la contenant. La composition aromatique comprend, comme principe actif, au moins une huile naturelle choisie dans le groupe comprenant l'essence de patchouli, l'encens et l'essence de bois de santal. La composition présente des effets de traitement physiologique et psychologique, des effets anti-stress, des effets soulageant la tension, des effets calmants, des effets stabilisateurs sur le plan émotionnel et des effets relaxants, et peut donc être utilisée dans le domaine de la beauté et des cosmétiques.
PCT/KR2012/004212 2011-05-27 2012-05-29 Composition aromatique ayant des effets anti-stress et relaxants et composition cosmétique la contenant Ceased WO2012165831A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201280025673.1A CN103619322B (zh) 2011-05-27 2012-05-29 具有缓解压力以及镇静效果的香料组合物以及包含其的化妆品组合物

Applications Claiming Priority (2)

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KR1020110050499A KR20120131970A (ko) 2011-05-27 2011-05-27 스트레스 완화 및 진정 효과를 갖는 향료 조성물 및 이를 함유하는 화장료 조성물
KR10-2011-0050499 2011-05-27

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WO2012165831A2 true WO2012165831A2 (fr) 2012-12-06
WO2012165831A3 WO2012165831A3 (fr) 2013-03-28

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KR102213993B1 (ko) 2016-11-24 2021-02-09 (주)아모레퍼시픽 둥근정향나무꽃의 향취를 재현한 향료 조성물

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