WO2013092579A3 - Verfahren zur herstellung eines oder mehrerer komplexbildner, ausgewählt aus methylglycindiessigsäure, glutaminsäurediessigsäure und deren salzen - Google Patents

Verfahren zur herstellung eines oder mehrerer komplexbildner, ausgewählt aus methylglycindiessigsäure, glutaminsäurediessigsäure und deren salzen Download PDF

Info

Publication number
WO2013092579A3
WO2013092579A3 PCT/EP2012/075939 EP2012075939W WO2013092579A3 WO 2013092579 A3 WO2013092579 A3 WO 2013092579A3 EP 2012075939 W EP2012075939 W EP 2012075939W WO 2013092579 A3 WO2013092579 A3 WO 2013092579A3
Authority
WO
WIPO (PCT)
Prior art keywords
acid
salts
producing
complexing agents
methylglycinediacetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2012/075939
Other languages
English (en)
French (fr)
Other versions
WO2013092579A2 (de
Inventor
Robert Baumann
Markus Christian Biel
Axel Franzke
Alfred Oftring
Friedhelm Teich
Paul Klingelhoefer
Guido Henze
Marie Katrin SCHRÖTER
Olesya KISTER
Sabine Borchers
Pavel TUZINA
Beate DEIMLING
Udo LEIDEL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
BASF SE
Original Assignee
BASF Schweiz AG
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF Schweiz AG, BASF SE filed Critical BASF Schweiz AG
Publication of WO2013092579A2 publication Critical patent/WO2013092579A2/de
Publication of WO2013092579A3 publication Critical patent/WO2013092579A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/70—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of the iron group metals or copper
    • B01J23/72—Copper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J21/00—Catalysts comprising the elements, oxides, or hydroxides of magnesium, boron, aluminium, carbon, silicon, titanium, zirconium, or hafnium
    • B01J21/06—Silicon, titanium, zirconium or hafnium; Oxides or hydroxides thereof
    • B01J21/066—Zirconium or hafnium; Oxides or hydroxides thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J35/00—Catalysts, in general, characterised by their form or physical properties
    • B01J35/60—Catalysts, in general, characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J35/61—Surface area
    • B01J35/613—10-100 m2/g
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J35/00—Catalysts, in general, characterised by their form or physical properties
    • B01J35/60—Catalysts, in general, characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J35/61—Surface area
    • B01J35/615—100-500 m2/g
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J37/00—Processes, in general, for preparing catalysts; Processes, in general, for activation of catalysts
    • B01J37/02—Impregnation, coating or precipitation
    • B01J37/03—Precipitation; Co-precipitation
    • B01J37/031—Precipitation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J37/00—Processes, in general, for preparing catalysts; Processes, in general, for activation of catalysts
    • B01J37/02—Impregnation, coating or precipitation
    • B01J37/03—Precipitation; Co-precipitation
    • B01J37/031—Precipitation
    • B01J37/033—Using Hydrolysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J37/00—Processes, in general, for preparing catalysts; Processes, in general, for activation of catalysts
    • B01J37/16—Reducing
    • B01J37/18—Reducing with gases containing free hydrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/02—Formation of carboxyl groups in compounds containing amino groups, e.g. by oxidation of amino alcohols
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2235/00—Indexing scheme associated with group B01J35/00, related to the analysis techniques used to determine the catalysts form or properties
    • B01J2235/15—X-ray diffraction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J35/00—Catalysts, in general, characterised by their form or physical properties
    • B01J35/70—Catalysts, in general, characterised by their form or physical properties characterised by their crystalline properties, e.g. semi-crystalline
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J35/00—Catalysts, in general, characterised by their form or physical properties
    • B01J35/80—Catalysts, in general, characterised by their form or physical properties characterised by their amorphous structures

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

Verfahren zur Herstellung eines oder mehrerer Komplexbildner, ausgewählt aus Methylglycindiessigsäure, Glutaminsäurediessigsäure und deren Salzen, durch katalytische Dehydrierung von N,N-Bis-(2-hydroxyethyl)-alanin und/oder N,N-Bis-(2-hydroxyethyl)-glutaminsäure bzw. deren Salzen in Gegenwart von Alkalihydroxid, wobei ein Katalysator enthaltend Kupfer und Zirkoniumdioxid eingesetzt wird, dessen Aktivierung eine Reduktion ist, dadurch gekennzeichnet, dass die Vorstufe des betreffenden Katalysators einen Kristallisationsgrad K, definiert als (I) im Bereich von 0 bis 50 % aufweist.
PCT/EP2012/075939 2011-12-23 2012-12-18 Verfahren zur herstellung eines oder mehrerer komplexbildner, ausgewählt aus methylglycindiessigsäure, glutaminsäurediessigsäure und deren salzen Ceased WO2013092579A2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP11195527 2011-12-23
EP11195527.4 2011-12-23
EP12164465 2012-04-17
EP12164465.2 2012-04-17

Publications (2)

Publication Number Publication Date
WO2013092579A2 WO2013092579A2 (de) 2013-06-27
WO2013092579A3 true WO2013092579A3 (de) 2013-08-15

Family

ID=47435947

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2012/075939 Ceased WO2013092579A2 (de) 2011-12-23 2012-12-18 Verfahren zur herstellung eines oder mehrerer komplexbildner, ausgewählt aus methylglycindiessigsäure, glutaminsäurediessigsäure und deren salzen

Country Status (1)

Country Link
WO (1) WO2013092579A2 (de)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2148287A (en) * 1983-10-05 1985-05-30 Nippon Catalytic Chem Ind Preparation of aminocarboxylic acid salts from amino alcohols
WO1998013140A1 (de) * 1996-09-26 1998-04-02 Akzo Nobel N.V. Katalysator zur dehydrogenierung von aminoalkoholen zu aminocarbonsäuren oder von ethylenglykol(derivaten) zu oxycarbonsäuren, verfahren zu seiner herstellung und seine verwendung
JPH11158130A (ja) * 1997-11-26 1999-06-15 Kao Corp アミノポリカルボン酸の製造法
CN101733100A (zh) * 2008-11-17 2010-06-16 浙江师范大学 用于制备亚氨基二乙酸的非晶态铜锆催化剂

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2148287A (en) * 1983-10-05 1985-05-30 Nippon Catalytic Chem Ind Preparation of aminocarboxylic acid salts from amino alcohols
WO1998013140A1 (de) * 1996-09-26 1998-04-02 Akzo Nobel N.V. Katalysator zur dehydrogenierung von aminoalkoholen zu aminocarbonsäuren oder von ethylenglykol(derivaten) zu oxycarbonsäuren, verfahren zu seiner herstellung und seine verwendung
JPH11158130A (ja) * 1997-11-26 1999-06-15 Kao Corp アミノポリカルボン酸の製造法
CN101733100A (zh) * 2008-11-17 2010-06-16 浙江师范大学 用于制备亚氨基二乙酸的非晶态铜锆催化剂

Also Published As

Publication number Publication date
WO2013092579A2 (de) 2013-06-27

Similar Documents

Publication Publication Date Title
MY182428A (en) Crystalline forms of a prolyl hydroxylase inhibitor
WO2012150155A9 (de) Verfahren zur herstellung eines kristallinen l-mgda-trialkalimetallsalzes
MX348977B (es) Preparación de sales de guanidina bicíclica en un medio acuoso.
UA102817C2 (ru) Способ синтеза агомелатина
MX2012002244A (es) Metodo para producir un solido cristalino de derivados de acido glicina-n, n-diacetico con higroscopicidad suficientemente reducida.
WO2012063252A3 (en) A method for preparing ramipril
NZ718607A (en) Synthetic route to 2’-deoxy-2’,2’-difluorotetrahydrouridines
MY157569A (en) Method for producing a solid with sufficiently low hygroscopicity which comprises glutamic acid-n,n-diacetic acid (glda) or a derivative thereof
FR2972452B1 (fr) Procede de preparation du difluoroacetonitrile et de ses derives
JO2928B1 (en) Method of synthesis of ferroquine by convergent reductive amination
PH12012502427A1 (en) Process for preparing crystalline 3,6,9-triaza-3,6,9-tris(carboxymethyl)-4-(4-ethoxybenzyl)undecanedioic acid and use for production of primovist
WO2009053840A3 (en) Solid forms of (±)-o-desmethylvenlafaxine salts
WO2012112841A3 (en) [1,2,4]oxadiazol-3-yl acid salts and crystalline forms and their preparation
WO2009122429A3 (en) Crystalline oxybutynin and process for preparing the same
WO2012140490A3 (en) Processes for preparing pitavastatin calcium
WO2011016052A3 (en) Process for preparing pregabalin
BR112015000966A2 (pt) método para a síntese de n-(fosfonometil)glicina ou um de seus derivados selecionados a partir do grupo que consiste em seus sais, seus ésteres de fosfonato e seus sais de éster de fosfonato
MX342570B (es) Proceso para producir granulos que comprende una o mas sales de agentes complejantes.
MX337997B (es) Nuevo procedimiento de sintesis de la ivabradina y de sus sales de adicion a un acido farmaceuticamente aceptable.
WO2013092579A3 (de) Verfahren zur herstellung eines oder mehrerer komplexbildner, ausgewählt aus methylglycindiessigsäure, glutaminsäurediessigsäure und deren salzen
EA028190B9 (ru) Монооксид азота в качестве катализатора цис/транс-изомеризации ненасыщенных соединений
MY157220A (en) Cyclohexanol, method for producing cyclohexanol, and method for producing adipic acid
WO2014133291A9 (ko) (2rs)-아미노-(3s)-히드록시-부티르산 또는 이의 유도체의 제조방법
IL178154A0 (en) Process for the preparation of gabapentin
WO2009101458A3 (en) New polymorph and amorphous forms of desvenlafaxine fumarate

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12806437

Country of ref document: EP

Kind code of ref document: A2

DPE1 Request for preliminary examination filed after expiration of 19th month from priority date (pct application filed from 20040101)
122 Ep: pct application non-entry in european phase

Ref document number: 12806437

Country of ref document: EP

Kind code of ref document: A2