Classifications

• • G—PHYSICS
  • G01—MEASURING; TESTING
  • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
  • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
  • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
• • G—PHYSICS
  • G01—MEASURING; TESTING
  • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
  • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
  • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
• • G—PHYSICS
  • G01—MEASURING; TESTING
  • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
  • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
  • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
  • G01N2035/00039—Transport arrangements specific to flat sample substrates, e.g. pusher blade
• • G—PHYSICS
  • G01—MEASURING; TESTING
  • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
  • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
  • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
  • G01N2035/00099—Characterised by type of test elements
  • G01N2035/00108—Test strips, e.g. paper

Definitions

• the present invention relates to an automatic dry chemical analyzer, and more particularly to a fully automatic dry chemical analyzer test strip dispensing device.
• test paper is placed on the side of the single reaction paper, and sent to the sample loading position, and each sample test paper is sampled by the sample needle and then sent to the instrument detection position for detection.
• the shortcomings of this method are mainly: a. It is difficult for the paper separation mechanism to ensure that all the test strips that are sent out are test paper faces up, and all are sent to the sample or detection position without bias. Therefore, the sample misdetection and the test paper waste phenomenon sometimes occur; b. Even if the test paper is normally sent to the sample loading position, it is difficult to ensure that each test paper block can be sampled and cause a certain Detection of missing items;
• test paper is immersed in the sample by the robot, and then the test paper impregnated with the sample is sent to the instrument detection position for detection.
• This approach solves the defect b of the previous method, but the defect a still exists, and the sample is contaminated and the excess sample causes contamination of the working environment because the reagent component on the test paper enters the sample.
• test paper can be conveniently stored to ensure that the test surface of the test strip faces upward, and each test item can be sampled, and the sample can be effectively avoided.
• Automatic dry chemical analyzer test strip dispensing device for contaminated working environment.
• an automatic dry chemical analyzer test strip dispensing device which comprises a plurality of test boxes equipped with test strips, which are stored in the test
• the test box conveying mechanism pushes the test box stored in the test box placing device to the test strip separation position, and the test strip dispensing mechanism will be in the test box in which the test strip is separated.
• the test strips are separated one by one and pushed one by one to the sample loading position.
• a sample loading device consisting of the pump valve line and the sample loading arm draws the sample and the test strip pushed to the sampled position is sampled by the leaching method.
• the test strip with the sample added is then pushed to the test position for detection by the testing mechanism.
• the test box is provided with a test strip outlet near one side of the test box, and the bottom of the test box is provided with a groove perpendicular to the test strip, and the test strip is layered and placed in the test box in a test-facing manner.
• the test box mounting device includes a top plate and a bottom plate, and the top plate and the bottom plate are supported by a pin connection, so that a cavity for storing the test box is formed between the top plate and the bottom plate.
• the pin on the output end of the test box mounting device is pivotally provided with a swinging plate disposed behind the storage test box, and an auxiliary pin is further disposed on the front side of the pin.
• a column, a tension spring is arranged between the auxiliary pin and the swing plate, so that the swingable swing plate is pulled by the tension spring and pressed on the test box.
• the driving mechanism includes a main motor, the main motor has an output shaft connected to the main and slave synchronous wheels, and the main and slave synchronous wheels are arranged with a timing belt, and the main and slave synchronous wheels are provided with a guide rod.
• the guiding rod is sleeved on the guiding rod, and the upper part of the guiding block is fixed with the lower section of the timing belt.
• the test box conveying mechanism comprises a mounting plate, the inside of the mounting plate is laterally mounted with two sliding bars, and the sliding rails are disposed between the two sliding bars, and the two sides of the double sliding slider are respectively sleeved on the two sliding bars
• Two sides of a "T" type pushing block are respectively sleeved on two sliding rods located in the double sliding block, and a first compression spring is arranged between the double sliding block and the pushing block, and the middle part of the pushing block is sleeved on the sliding
• one end of the double-type slider is provided with an automatically resetting claw
• the push block is provided with an automatically resettable claw
• the bottom surface of the push block is fixedly connected with a connecting plate, the connecting plate and the driving
• the guiding block of the mechanism is fixedly connected, and one end of the mounting plate is further provided with a first stop which can be automatically reset.
• the test strip dispensing mechanism includes a base, two sides of the base are mounted, and a push rail is disposed on the base between the two supports, and the bottom side of the push slide is installed There is a motor, the output shaft of the push-out motor protrudes to the other side of the push-out rail, and the output shaft of the push-out rail is mounted with a push-out main synchronous wheel, and the bottom of the push-out rail is pivoted from the other end of the slide rail.
• the push-out main belt and the slave synchronous wheel are arranged to push out the timing belt, and the upper part of the push-out belt is fixedly arranged to push out the push rod frame, and the middle part of the push rod frame is also sleeved on the pushing slide rail, so that the push rod
• the rack can be smoothly moved along the push rail, and the push rod frame is provided with juxtaposed push rods, and the front end of the push rods defines a notch for accommodating the test strip, and the height of the notch is greater than one and less than The height of 2 test strips.
• test box conveying mechanism can also include a line rail, the sliding rail is sleeved on the line rail, and the pushing member is fixedly connected with the guiding block of the driving mechanism, so that the main motor can be Driving the pusher member to move along the line.
• the pusher member is pivotally provided with a push pin, the lower end of the push pin protrudes from the push pin member, and abuts against one side of the outermost test box located in the test box mounting device, and the upper end of the push pin is coupled to the second compression spring
• the push part is connected, and a second baffle is arranged on the side of the test strip separation position.
• the push test box is moved to the test strip separation position by the second baffle, and then moved with the push part It is placed against the top side of the test box and finally moved to the other side of the test box to prepare for returning the test box.
• the present invention has the following beneficial effects:
• the test strip used in the present invention is stored in the test box.
• the push rod moves back and forth through the groove at the bottom of the test box, and the test strip falling on the front end of the push rod is pushed one by one to the sample loading position, and is pushed.
• the push slide rail disposed under the push rod frame ensures that the push rod can smoothly move forward with the test strip, so that the test strip can be pushed to the sample loading position without being biased, and after being sent to the sample loading position,
• the sample loading device adopts the leaching method to load the test strips, so that each test block on the test strip can be spotted, and the item missed condition is not caused because the sample is not spotted. [0012] 2.
• the present invention is further provided with a chute in the lower part of the front end of the push rod, the front end of the chute is facing downward, and the front end of the chute is provided with a flip tip through a compression spring, and the inverted tip is located at the front end of the push rod.
• the inverted tip abuts against the front side of the test strip, and as the test strip advances forward, the inverted tip presses the compression spring to move under the chute, thereby further ensuring that the test strip pushed by the push rod can be unbiased. Improperly pushed to the sample position.
• the invention puts the test paper or reagent in the test slot, and puts the test strips into the test box in the order of the test surface, which is not only convenient for storage, but also can effectively ensure the detection during the sample loading.
• the test surface is facing up, and does not cause the sample to be misdetected and the test paper is wasted, and the total weight of the test strip is increased due to the addition of the test slot, so that the flipping, winding and offset are less likely to occur during the transfer process.
• the test tank can also carry excess specimen liquid so that it does not flow directly onto the workbench, polluting the working environment.
• the multi-item chemical reaction test paper is embedded in the test slot and rests on the protrusion on the bottom of the groove, so as to effectively block the side leakage of the sample liquid on the test paper, and the sample liquid used in each test item does not flow together. , effectively avoiding cross-contamination between adjacent projects.
• the multi-item chemical reaction test strip used in the present invention may also be a test tank having a plurality of reaction pores at the inner bottom, each of which contains different chemical reaction reagents, each of which is a reaction well.
• the independent space can effectively block the side leakage of the reaction liquid of each project to avoid cross-contamination between adjacent projects.
• FIG. 1 is a schematic view of the overall structure of the present invention.
• FIG. 2 is a schematic structural view of a test box mounting device of the present invention.
• FIG 3 is a schematic structural view of a driving mechanism of the present invention.
• FIG. 4 is a schematic structural view of a first embodiment of a test box conveying mechanism of the present invention.
• FIG. 5 is a schematic view showing the action state of the first embodiment of the test box conveying mechanism of the present invention.
• FIG. 6 is a schematic structural view of a test strip dispensing mechanism of the present invention.
• FIG. 7A is a schematic structural view of a first embodiment of a test strip of the present invention.
• FIG. 7B is a schematic structural view of a second embodiment of the test strip of the present invention.
• FIG. 8 is a perspective exploded view of an embodiment of a test box structure of the present invention.
• FIG. 9 is a perspective view of the stereo combination of FIG. 8.
• FIG. 10 is a schematic view showing a state in which a test strip of the present invention is pushed from a test cartridge mounting device to a sample loading position.
• FIG. 11 is a schematic view showing the structure and operation state of a second embodiment of the test box conveying mechanism of the present invention.
• FIG. 12 is a schematic structural view of a second embodiment of a test strip dispensing mechanism according to the present invention.
• the automatic dry chemical analyzer test strip dispensing device of the present invention comprises a test with a test strip installed thereon. a cassette 5, a test box mounting device 6 and a drive mechanism 7, a test box transport mechanism 8, a test strip dispensing mechanism 9, and a sample loading device consisting of a pump valve line and a sample loading arm (the sample loading device is a known structure)
• the applicant only changes the loading mode of the sample loading device from the original spotting mode to the splicing mode, so that each test block on the test strip can be spotted, not because The item missed condition does not appear in the sample, and the improvement is completely realized by the control software, so the structure of the sample loading device is not described too much here.
• the test box mounting device 6 includes a top plate 29 and a bottom plate 33.
• the top plate 29 and the bottom plate 33 are connected and supported by a pin 31, thereby forming a cavity between the top plate 29 and the bottom plate 33.
• An oscillating plate 30 disposed at the rear of the storage test box 5 is pivotally disposed on the pin 31 of the output of the test box mounting device 6.
• the front side of the pin 31 is further provided with an auxiliary pin 311, and the auxiliary pin 311 is
• a tension spring 32 is provided between the swinging plates 30 to cause the swingable swinging plate 30 to be pulled by the tension spring 32, thereby pressing the test box 5.
• the driving mechanism 7 includes a motor bracket 11, one end of the motor bracket 11 locks the main motor 10, and the main synchronous wheel 13 is mounted on the output shaft of the main motor 10, and the motor bracket 11 is mounted on the output shaft of the main motor 10.
• the other end is provided with a timing belt 14', and the timing belt 14 is wound around the main and slave timing wheels 13, 13'.
• a guide bar 15 is disposed below the main and slave synchronous wheels 13, 13', and a guide block 12 is disposed on the guide bar 15, and an upper portion of the guide block 12 is fixed to a lower portion of the timing belt 14.
• the main motor 10 is a stepping motor capable of realizing forward and reverse rotation, and can drive the synchronous wheel 13 to perform forward and reverse rotation, so that the guide block 12 can be slid along the guide rod 15 by the timing belt 14 disposed thereon.
• the test box transport mechanism 8 includes a mounting plate 16, and the inside of the mounting plate 16 is laterally mounted with two sliding bars 19, and a sliding rail 24 is disposed between the two sliding bars 19.
• the two sides of a double slider 18 are respectively sleeved on the two slide bars 19.
• Two sides of a "T" type push block 22 are respectively sleeved on the two sliding bars 19 located in the double block slider 18, and a first compression spring 20 is disposed between the double block slider 18 and the push block 22, so that the push block is When the 22 is in motion, the double slider 18 also acts accordingly, and the middle portion of the push block 22 is sleeved on the slide rail 24.
• One end of the double slider 18 is provided with two first torsion springs 25, and each of the first torsion springs 25 is provided with a claw 26.
• the push block 22 is mounted with a finger 23 via a second torsion spring 21 so that the finger 23 can be rotated by a specific angle.
• the bottom surface of the push block 22 is fixedly connected to a connecting plate 17, and the connecting plate 17 is fixedly connected to the guiding block 12 of the driving mechanism 7.
• One end of the mounting plate 16 is also provided with a first stopper 28 via a third torsion spring 27 such that the first stopper 28 can be rotated by a specific angle.
• the first torsion springs 28 are respectively rotated by the first torsion springs 25, and the second torsion springs 27 are rotated by a certain angle by the first torsion springs 28, and then the claws 26, After the limit condition of the finger 23 and the first stopper 28 is released, the automatic reset can be performed, but the present invention is not limited thereto, and any measure for automatically resetting the claw 26, the finger 23 and the first stopper 28 is It is covered by the scope of this patent.
• test cartridge transport mechanism 8 The action of the test cartridge transport mechanism 8 is as shown in FIG. 5.
• the push block 22 When the test cartridge 5 is at the test strip separation position a, the push block 22 is at the position A (ie, the position shown in FIG. 4), when in the separation position a.
• the connecting plate 17 connected to the guiding block 12 drives the push block 22 to move to the position B, thereby pushing the empty test box 5 to move forward, and the double slider 18 also moves forward accordingly.
• the claw 26 collides with the first stopper 28, the first stopper 28 does not move, the claw 26 falls, and the push block 22 continues to move to the position C, at which time the test box 5 is fully pushed out, the finger 23 and the first gear
• the blocks 28 collide, the first block 28 does not move, and the finger 23 swings past the first block 28.
• the push block 22 is retracted to the position B by the action of the main motor 10, and the double slide 18 is also retracted by the pulling force of the push block 22 and the first compression spring 20, where During the process, the finger 23 again collides with the first stopper 28, at this time, the finger 23 does not move, the first stopper 28 falls, the claw 26 is lifted up, and the test box 5 in the storage position b enters. In the neutral position between the claw 26 and the push block 22, the push block 22 continues to retreat to the position A, and the pull claw 26 drives the test cartridge 5 to the separation position a.
• the test strip dispensing mechanism 9 includes a base 40.
• the middle portion of the base 40 is provided with a push-out rail 36.
• One side of the push-out rail 36 is provided with a push-out motor 39.
• Two push-out timing wheels 38 are pivotally disposed on one side, and a push-out timing belt 37 is disposed between the two push-out synchronous wheels 38.
• the output shaft of the push-out motor 39 passes through the push-out slide rail 36 as a pivot of one of the push-out synchronization wheels 38.
• the upper portion of the timing belt 37 is fixedly mounted with a push rod holder 35.
• the middle portion of the push rod holder 35 is sleeved on the ejection rail 36 so that the push rod holder 35 can smoothly move along the ejection rail 36.
• the push rod holder 35 At least two parallel push rods 351 are disposed at the front end of the push rods 351, and a front end of the push rods 351 defines a notch 352 for accommodating the test strips 41.
• the height of the gap 352 is greater than one and less than the height of the two test strips 41.
• the upper and lower ends of the mounting plate 16 of the test box conveying mechanism 8 are respectively connected to the top plate 29 and the bottom plate 33 of the test box mounting device 6, and the driving mechanism 7 is mounted on the top plate. Above the 29, the guide block 12 of the drive mechanism 7 is fixedly connected to the connecting plate 17 of the test cartridge transport mechanism 8.
• the first embodiment of the test strip 41 used in the present invention includes a test slot 412 having a plurality of projections for the overhead multi-item chemical reaction test paper on the inner bottom surface of the test slot 412. 413;
• the multi-item chemical reaction test strip 411 is embedded in the test slot 412 and rests on the protrusion 413;
• the test slot 412 is provided with a first guiding groove or guiding rib 414 at one end or both ends.
• the second embodiment of the test strip 41 used in the present invention is substantially the same as the first embodiment except that the inside of the test slot 412 is uniformly distributed with a plurality of reaction holes 415, and each Different chemical reaction reagents are contained in the reaction wells 415, respectively.
• the test cartridge 5 used in the present invention is used to store the test strip 41.
• the test box 5 - the embodiment includes an outer box 51 and an inner drawer 52.
• the inner side of the side panel 52 is provided with a second guiding convex that cooperates with the first guiding groove or the guiding rib 414 on the test strip 41.
• a rib or a guiding groove 521 one end of the outer box 51 is provided with an opening 511, and the inner drawer 52 is embedded in the outer box 51 from the opening 511.
• a test strip outlet 53 is formed to enable the test strip 41 to be inside.
• the drawer 52 is laterally pushed out.
• the lower portion of the inner drawer 52 is further provided with a recess 54 that cooperates with the push rod 351.
• the test box 5 can store tens to hundreds of pieces per box as needed, and the test slots 412 of all the test strips 41 are stored in the inner drawer 52 of the test box 5 in a downward direction of the test-facing test strip.
• test box 5 is a structure in which the outer box 51 is combined with the inner drawer 52
• the test box of the present invention is not limited thereto, and the test strip outlet 53 may be opened on the bottom side.
• the integrated box body is provided with a second guiding rib or guiding groove 521 which is matched with the first guiding groove or the guiding rib 414 on the test strip 41 on the inner side of the opposite side plates of the box body.
• the pusher frame 35 of the test strip dispensing mechanism 9 is mounted on the rear side of the test box 5, and each push rod 351 is established corresponding to a recess 54 at the bottom of the test box 5.
• the push rod 351 pushes the timing belt 37 under the action of the push-out motor 39 to drive the push rod holder 35 forward until the notch 352 is located just below the test box 5, so that a test strip 41 is just right.
• Falling into the notch 352 of the two push rods 351, and under the action of the pushing motor 39 the push rod 351 moves forward through the groove 54 at the bottom of the test box, and the test strip 41 falling on the front end of the push rod 351 is sent to the loading sample.
• the sample loading position of the device (not shown) is applied to the test strip 41 by the sample loading device.
• the sample loading device is of known structure, and therefore will not be described too much herein.
• the sample loading device only changes the sample loading mode to the leaching sample, so that the sample can be fully contacted with the test paper or the reagent, and Some test items have been missed due to lack of spotting.
• test box mounting device 6 is first placed in a test box 5 equipped with test strips 41, which are on the rear side swinging plate 30 and the tension spring 32. Under the combined action, it is pressed between the swinging plate 30 and the test box conveying mechanism 8. At this time, the frontmost test box 5 is just clamped by the push block 22 and the pull claw 26, and the main motor 10 is activated to move the guide block 12, the connecting plate 17 and the push block 22, and the test box 5 is sent to the separation position. a.
• the motor 39 is restarted, so that the notch 352 of the push rod 351 is located just below the inner box 52 of the test box 5, and then the push rod holder 35 is driven by the push-out motor 39 to push out the test strip 41 to the loading position c.
• the test strip 41 is sent to the tester (not shown) for inspection; after the test strip 41 is sent to the tester, the pusher frame 35 is reset by the push-out motor 39 to start the next push-out action. Until the test strip 41 runs out, the above actions are started.
• the second embodiment of the test cartridge transport mechanism 8 includes a line rail 71 on which the push pin member 72 is slidably sleeved, and the push pin member 72 is steerable with the drive mechanism 7.
• the block 12 is fixedly coupled such that the push pin member 72 can actuate the push pin member 72 along the line rail 71 under the action of the main motor 10.
• the push pin member 72 is pivotally provided with a push pin 74 via a pivot 73.
• the lower end of the push pin 74 extends from the push pin member 72 and can be used for dialing the test box 5 on one side thereof to the test strip separation position.
• a second baffle 75 is provided on the side.
• the upper end of the push pin 74 is connected to the push pin member 72 via a compression spring 76.
• the timing belt 14 drives the push pin member 72 to move along the line rail 71, and the push pin 74 moves with the push pin member 72 from the position a to the right to move the test box 5 on the bottom plate 33 of the test box mounting device 6, when Measurement After the test box 5 is blocked by the second baffle 75, the push pin member 72 continues to move to the right, and the push pin 74 receives a large resistance from the test box 5, and pivots around the pivot 73 at b to climb to the top of the test box 5, continuing to go to c Press the test box 5 to stabilize the test box 5 at the separation position of the test strip.
• test strip dispensing mechanism 9 After the test strip dispensing mechanism 9 completes the test strip dispensing work, push the row 74 to the d to leave the test box 5, and the push pin 74 is reversed. Moving left, the test cartridge 5 is pushed out, and the entire pusher member 72 returns to a (starting point), completing the action of the entire push test box.
• FIG. 12 it is a schematic structural view of a second embodiment of the test strip dispensing mechanism of the present invention.
• the front end of the push rail 36 can also be respectively provided with a plate 42.
• Each of the plates 42 is fixed with a chute 43 at the lower end of the front end of the push rod 351.
• the front end of the chute 43 faces downward, and the chute
• the front end of the 43 is provided with a tip 44 which is located at the front end of the push rod 351 by a compression spring.
• the inverted tip 44 abuts against the front side of the test strip 41, and as the test strip 41 travels forward, the inverted tip 44 continuously presses the compression spring to move under the chute 43 to further ensure the push rod.
• the test strip 41 pushed by the 351 can be pushed to the loading position without bias.
• the push rod can also be provided with an arc-shaped convex structure 45 at the position of the notch, so that when the test strip 41 is pushed out from the test box 5, when the convex structure 45 passes through the test box 5, the convex structure 45
• the test strip 41 to be separated in the test box 5 can be gradually topped up, so as to effectively prevent the test strip to be separated from sticking to the test strip being pushed out, and ensure that the test strip 41 being pushed out can be pushed out smoothly.
• the test strip to be separated in the test box 5 is arranged to be evenly stored in the test box 5, so that the test strip 41 is not stuck in the test box 5.

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• Physics & Mathematics (AREA)
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• Life Sciences & Earth Sciences (AREA)
• Chemical & Material Sciences (AREA)
• Analytical Chemistry (AREA)
• Biochemistry (AREA)
• General Health & Medical Sciences (AREA)
• General Physics & Mathematics (AREA)
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Cited By (4)

Citations (8)

• 2012
  • 2012-02-23 WO PCT/CN2012/071521 patent/WO2013123661A1/fr not_active Ceased

Patent Citations (8)

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