WO2014127547A1 - Matrice de couverture de dent et procédés de blanchiment de dent - Google Patents

Matrice de couverture de dent et procédés de blanchiment de dent Download PDF

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Publication number
WO2014127547A1
WO2014127547A1 PCT/CN2013/072167 CN2013072167W WO2014127547A1 WO 2014127547 A1 WO2014127547 A1 WO 2014127547A1 CN 2013072167 W CN2013072167 W CN 2013072167W WO 2014127547 A1 WO2014127547 A1 WO 2014127547A1
Authority
WO
WIPO (PCT)
Prior art keywords
whitening
agent
resin layer
whitening agent
tooth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2013/072167
Other languages
English (en)
Chinese (zh)
Inventor
何靖
陈诗薇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EASTING BIOTECHNOLOGY CO Ltd
Original Assignee
EASTING BIOTECHNOLOGY CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EASTING BIOTECHNOLOGY CO Ltd filed Critical EASTING BIOTECHNOLOGY CO Ltd
Publication of WO2014127547A1 publication Critical patent/WO2014127547A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • A61C19/066—Bleaching devices; Whitening agent applicators for teeth, e.g. trays or strips

Definitions

  • the present invention relates to a dental overmold and a method for whitening the teeth thereof, and more particularly to a dental overmold using a whitening agent in combination with an alkaline contact agent for performing a whitening reaction and a method for whitening the teeth.
  • Teeth whitening is one of the most fashionable beauty projects, and a mild oxidizing agent is commonly applied to the teeth to destroy pigmentation on the teeth.
  • a mild oxidizing agent is commonly applied to the teeth to destroy pigmentation on the teeth.
  • tooth whitening agents for example, the addition of fluoride to increase the effectiveness of dental caries, the addition of sodium nitrate to reduce the irritation of tooth whitening agents on the gums, the addition of spices, the addition of antihistamines, etc.
  • fluoride to increase the effectiveness of dental caries
  • sodium nitrate to reduce the irritation of tooth whitening agents on the gums
  • spices the addition of antihistamines, etc.
  • antihistamines etc.
  • the method of whitening teeth used in the prior art is usually applied by the user to the teeth in the oral cavity, but the problem is that the unevenness of the application and the enzyme contained in the saliva interfere with the whitening agent, so the effect of whitening is not uniform and effective.
  • the whitening agent is applied to the tooth mold so that the user can put the tooth mold into the mouth when the white teeth are needed.
  • the method of applying the whitening agent to the tooth mold may reduce the chance of the user swallowing the medicament.
  • the method of previously applying the whitening agent to the tooth form of the tooth exposes the agent to the air early, which affects the whitening efficiency of the agent.
  • a dental sleeve mold comprising a thermoplastic resin layer, a whitening agent layer, and an alkali-soluble resin layer.
  • the whitening agent layer may be disposed on one side of the thermoplastic resin layer and contains a whitening agent.
  • the alkali-soluble resin layer is disposed on the whitening agent layer.
  • the thermoplastic resin layer is an acid-resistant oxidizing agent, and the softening temperature of the thermoplastic resin layer It is 35 ⁇ 95 °C.
  • thermoplastic resin layer may be composed of one or a combination of polyurethane, polyacrylic acid, polyvinyl acetate.
  • the whitening agent layer is a polypropylene non-woven fabric.
  • the whitening agent comprises hydrogen peroxide or urea peroxide.
  • the whitening agent further comprises a stabilizer which is an acidic buffer for shielding transition metal ions.
  • the acidic buffer comprises tartaric acid, phosphoric acid, phytic acid or pyrophosphoric acid.
  • the alkali-soluble resin layer is obtained by kneading polyacrylic acid and polyacrylic acid methyl ester.
  • Another main object of the present invention is to provide a tooth whitening method for applying the above-mentioned tooth cover film to teeth, comprising the steps of: applying an alkaline contact agent to an alkali-soluble resin layer to dissolve the alkaline contact agent; The alkali-soluble resin layer is then reacted with a whitening agent to cause the whitening agent to release at least one reactive oxygen medium.
  • the whitening agent after the reaction with the alkaline contact agent is confined between the dental mold and the teeth to perform a tooth whitening reaction.
  • the basic catalyzing agent comprises sodium hydroxide as a Lewis base and a neutral or basic amino acid as a Lewis acid.
  • the Lewis acid comprises glycine, alanine, lysine or arginine.
  • the alkaline contact agent may have a pH of from 7 to 11.5.
  • the at least one reactive oxygen medium may comprise hydrogen peroxide ion (HOO-), oxygen radical (0-), ozone radical (0 3 ⁇ ) or ozone (0 3 ).
  • the tooth cover mold of the present invention and the method for applying the tooth whitening method have the advantages of greatly reducing the probability of mixing saliva with the medicine, and not allowing the whitening agent to easily flow into the oral cavity, and further enabling the whitening agent to be used only when needed. Mildly activated to achieve tooth whitening effect.
  • Figure 1 is a schematic view showing the structure of a dental sleeve mold of the present invention.
  • FIG. 2 is a flow chart of a method for applying a tooth cover mold to teeth whitening according to the present invention.
  • Reference numeral 1 Dental mold.
  • the dental sleeve mold 1 comprises a thermoplastic resin layer 10, a whitening agent layer 11, and an alkali-soluble resin layer 12.
  • the whitening agent layer 11 is provided on one side of the thermoplastic resin layer 10, and the whitening agent layer 11 contains a whitening agent.
  • the alkali-soluble resin layer 12 is provided on the whitening agent layer 11.
  • the thermoplastic resin layer 10 is an acid-resistant oxidizing agent, and the thermoplastic resin layer 10 may have a softening temperature of 35 to 95 °C.
  • the thermoplastic resin layer 10 is composed of a combination of one or a combination of polyurethane, polyacrylic acid, and polyvinyl acetate.
  • the whitening agent layer 11 is a polypropylene non-woven fabric having a whitening agent containing hydrogen peroxide or urea peroxide. It is worth noting that the whitening agent may also contain a stabilizer, an acidifying agent for shielding the transition metal ions, for example: tartaric acid, phosphoric acid, phytic acid or pyrophosphoric acid. Further, the alkali-soluble resin layer 12 may be a mixture of polyacrylic acid and polyacrylic acid methyl ester.
  • the alkaline contact agent dissolves the alkali-soluble resin layer.
  • the alkaline contact agent reacts with the whitening agent to release the whitening agent to release at least one reactive oxygen medium for whitening the teeth.
  • the user may first apply the alkaline contact agent to the alkali-soluble resin layer 12, at which time the alkaline contact agent dissolves the alkali-soluble resin layer 12 first, and then gradually with the alkali-soluble resin layer 12
  • the whitening agent contained in the coated whitening agent layer 11 is reacted to cause the whitening agent to release at least one reactive oxygen medium. It is worth noting that since the user can customize the dental mold 1 according to the tooth size or tooth state of each user, the whitening agent after reacting with the alkaline contact agent will be limited to the dental mold 1 and the user. Tooth whitening reaction between the teeth without easily leaking the whitening agent or alkaline contact agent.
  • the dental sleeve mold 1 of the present invention can be regarded as a thermoplastic composite sheet structure. After the thermoplastic composite sheet is softened by heating, it can be attached to the teeth of the user, and the thermoplastic composite sheet is molded by using the teeth as a male mold. The female mold of the shape of the user's teeth is removed after cooling to obtain the dental mold of the present invention.
  • the structure of the dental sleeve 1 is based on a thermoplastic resin, and is selected from a thermoplastic resin having an acid-resistant oxidizing agent having a softening point of between 45 and 75 ° C, and a non-woven fabric impregnated with a whitening agent is disposed thereon.
  • the upper layer of the whitening agent impregnated nonwoven fabric is coated with an alkali-soluble resin film.
  • the alkali-soluble resin film can protect the whitening agent impregnated non-woven fabric from contamination or dilution during the thermoplastic forming operation, and the material can be selected by mixing acrylic acid and methyl acrylate.
  • the structure of the above dental sleeve 1 is used by first spraying a thermoplastic tooth mold into hot water, allowing the temperature of the dental mold to exceed the first glass transition temperature Tgl of the thermoplastic resin and approaching the melting point, and then taking out and attaching it.
  • Tgl first glass transition temperature
  • the user can apply a quantitative alkaline contact agent to the alkali-soluble resin film surface of the dental mold, and can fit the tooth mold over the teeth, when the alkaline contact agent and the alkali are dissolved.
  • the reaction procedure is triggered.
  • the alkaline contact agent dissolves the alkali-soluble resin film on the surface of the dental mold
  • the whitening agent enclosed in the dental mold is released, and the release activity is released after the whitening agent is contacted with the alkaline contact agent.
  • the reaction of the oxygen medium, the active oxygen medium can whiten the teeth. Therefore, the tooth cover mold of the present invention can not only reduce the effect of the drug being diluted into the oral cavity by saliva, but also prevent the user from being uncomfortable by swallowing an excessive amount of the drug.
  • the whitening agent of the present invention is a substance which forms a hydrogen bond or an ionic bond in combination with a tooth whitening agent (as an oxidizing agent), binds to a tooth whitening agent, and can form a hydrogen bond or an ionic bond with a tooth whitening agent (as an oxidizing agent).
  • the tooth whitening agent can be stabilized without losing the oxidizing ability to achieve stable storage and avoid eroding the packaging container.
  • Hydrogen peroxide can form urea peroxide with urea to achieve the goal of stabilization.
  • the whitening agent can be added with the necessary stabilizer, and the stabilizer can be selected with an acidic buffer that shields the transition metal ions, such as tartaric acid, phosphoric acid, phytic acid, Pyrophosphate and the like.
  • the tooth mold of the present invention pre-sets the whitening agent in the whitening agent layer of the dental mold, the whitening agent is stored separately from the alkaline contact agent until the tooth whitening is performed before mixing. Make sure you get a higher level of efficacy during use.
  • the whitening agent contained in the dental sleeve of the present invention is quantitatively disposed therein to prevent the user from using an excessive or insufficient whitening agent under the operation of applying the whitening agent by itself, thereby affecting the effect of whitening the teeth.
  • the alkaline contact agent used in the present invention can be used to leach the whitening agent to precipitate a reactive oxygen medium, which comprises hydrogen peroxide ion (HOO-), oxygen radical ( ⁇ ), ozone radical (0 3 ⁇ ) or ozone (0 3 ) and so on.
  • the alkaline contact agent is configured such that sodium hydroxide is a Lewis base, a neutral or basic amino acid is a Lewis acid, and the neutral or basic amino acid may be selected from the group consisting of glycine, alanine, and lysine. , arginine, etc.
  • the pH of the alkaline contact agent can range from 8 to 10.5.
  • thermoplastic resin Ethylene-vinyl acetate was used as a thermoplastic resin layer (having a thickness of about 0.8 awake, a melting point of about 70 ° C, and VA 30 ); and cutting into a suitable shape.
  • the adhered polypropylene non-woven fabric was used as a whitening agent layer (having a thickness of about 0.4 mm), and was placed on the thermoplastic resin layer by pressurization and heat fusion.
  • the formulation of the whitening agent is: 30% hydrogen peroxide 100 ml, urea 63 g, 50% phytic acid 0.5 ml, pure water to a volume of about 150 ml, and a pH of 3.5 to 4.5.
  • the whitening agent was dropped into the whitening agent layer of the polypropylene non-woven fabric, and after drying, it became a whitening agent layer having a whitening agent.
  • the alkali-soluble resin layer was applied to the whitening agent layer to a thickness of about 0.02 mm.
  • the alkali-soluble resin layer may be obtained by kneading polymethyl methacrylate (PMMA) and polyacrylic acid (PAA) at a ratio of 55% to 45%.
  • alkaline contact agent The main formula of alkaline contact agent:
  • Glycine 200 g / L using pure water as a solvent, with sodium hydroxide to control its pH of 9.5 ⁇ 10.5. Among them, the amount of whitening of each tooth is about 1 ml.

Landscapes

  • Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne une matrice de couverture de dent et un procédé de blanchiment de dent. La matrice de couverture de dent comprend une couche de résine thermoplastique, une couche d'agent de blanchiment, et une couche de résine soluble dans un alcali. La couche d'agent de blanchiment est disposée sur un côté de la couche de résine thermoplastique et comprend un agent de blanchiment. La couche de résine soluble dans un alcali est disposée sur la couche d'agent de blanchiment. Le procédé de blanchiment de dent utilisant la matrice de couverture de dent comprend les étapes suivantes : application d'un agent de contact alcalin sur la couche de résine soluble dans un alcali, dissolution de la couche de résine soluble dans un alcali par l'agent de contact alcalin, et réaction avec l'agent de blanchiment pour amener l'agent de blanchiment à libérer au moins une espèce active de l'oxygène.
PCT/CN2013/072167 2013-02-21 2013-03-05 Matrice de couverture de dent et procédés de blanchiment de dent Ceased WO2014127547A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201310055123.0 2013-02-21
CN2013100551230A CN103142324A (zh) 2013-02-21 2013-02-21 牙齿套模及其牙齿美白方法

Publications (1)

Publication Number Publication Date
WO2014127547A1 true WO2014127547A1 (fr) 2014-08-28

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PCT/CN2013/072167 Ceased WO2014127547A1 (fr) 2013-02-21 2013-03-05 Matrice de couverture de dent et procédés de blanchiment de dent

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CN (1) CN103142324A (fr)
WO (1) WO2014127547A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101831259B1 (ko) * 2016-01-04 2018-02-23 오스템임플란트 주식회사 안정성이 향상된 치아 미백제 조성물
CN111419462A (zh) * 2019-01-09 2020-07-17 曹荣华 一种口腔保健用品

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6343932B1 (en) * 2000-11-13 2002-02-05 Peter E. Wiesel Delivery system for whitening teeth
WO2004105629A2 (fr) * 2003-05-27 2004-12-09 Ultradent Products, Inc. Dispositifs de blanchiment dentaire et procedes et trousses dans lesquels ils sont utilises
CN1571654A (zh) * 2001-08-17 2005-01-26 史密丝克莱恩比彻姆有限公司 口腔护理物质递送膜片
WO2005123024A1 (fr) * 2004-06-09 2005-12-29 Lornamead Brands, Inc. Produits pour le blanchiment des dents et leurs procedes de fabrication
CN1956696A (zh) * 2004-05-10 2007-05-02 高露洁-棕榄公司 多层牙齿增白条

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Publication number Priority date Publication date Assignee Title
ES2221173T3 (es) * 1997-06-06 2004-12-16 THE PROCTER & GAMBLE COMPANY Sistema de administracion para un blanqueante dental que usa una tira de material que tiene baja rigidez de flexion.
KR100403699B1 (ko) * 2000-03-17 2003-11-01 주식회사 엘지생활건강 치아 미백용 패취
US20020146666A1 (en) * 2001-04-04 2002-10-10 Sagel Paul Albert Kits for whitening teeth
US8840918B2 (en) * 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
CN1522687A (zh) * 2003-02-17 2004-08-25 北京泰瑞伟业科技有限公司 用粘结材料作为载体的口腔保健产品
CN101411646A (zh) * 2008-10-27 2009-04-22 金耀 一种含有激活剂的牙齿漂白系统
CN202211758U (zh) * 2011-08-19 2012-05-09 沃康生技股份有限公司 牙模片结构

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6343932B1 (en) * 2000-11-13 2002-02-05 Peter E. Wiesel Delivery system for whitening teeth
CN1571654A (zh) * 2001-08-17 2005-01-26 史密丝克莱恩比彻姆有限公司 口腔护理物质递送膜片
WO2004105629A2 (fr) * 2003-05-27 2004-12-09 Ultradent Products, Inc. Dispositifs de blanchiment dentaire et procedes et trousses dans lesquels ils sont utilises
CN1956696A (zh) * 2004-05-10 2007-05-02 高露洁-棕榄公司 多层牙齿增白条
WO2005123024A1 (fr) * 2004-06-09 2005-12-29 Lornamead Brands, Inc. Produits pour le blanchiment des dents et leurs procedes de fabrication

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