WO2016205902A3 - Compositions et méthodes pour le traitement de biofilms - Google Patents

Compositions et méthodes pour le traitement de biofilms Download PDF

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Publication number
WO2016205902A3
WO2016205902A3 PCT/BE2016/000028 BE2016000028W WO2016205902A3 WO 2016205902 A3 WO2016205902 A3 WO 2016205902A3 BE 2016000028 W BE2016000028 W BE 2016000028W WO 2016205902 A3 WO2016205902 A3 WO 2016205902A3
Authority
WO
WIPO (PCT)
Prior art keywords
biofilms
composition
compositions
methods
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/BE2016/000028
Other languages
English (en)
Other versions
WO2016205902A8 (fr
WO2016205902A2 (fr
Inventor
Bruno Cammue
Tanne COOLS
Jan Wouter Drijfhout
Karin Thevissen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Katholieke Universiteit Leuven
Leids Universitair Medisch Centrum LUMC
Original Assignee
Katholieke Universiteit Leuven
Leids Universitair Medisch Centrum LUMC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1511051.3A external-priority patent/GB201511051D0/en
Priority claimed from GBGB1511447.3A external-priority patent/GB201511447D0/en
Application filed by Katholieke Universiteit Leuven, Leids Universitair Medisch Centrum LUMC filed Critical Katholieke Universiteit Leuven
Publication of WO2016205902A2 publication Critical patent/WO2016205902A2/fr
Publication of WO2016205902A3 publication Critical patent/WO2016205902A3/fr
Publication of WO2016205902A8 publication Critical patent/WO2016205902A8/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Paints Or Removers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne une nouvelle composition destinée à être utilisée dans l'inhibition ou le traitement de la formation d'un biofilm microbien, ladite composition comprenant une défensine de plante ou un dérivé peptidique de celle-ci et un composé antifongique, de préférence la caspofungine, l'anidulafungine, la micafungine, ou l'amphotéricine B. Par conséquent, la présente invention concerne l'utilisation de ladite composition pour l'inhibition ou le traitement de biofilms, en particulier des biofilms fongiques, tels que des biofilms de Candida, chez un sujet ou sur une surface ou un autre milieu sensible à la formation de biofilms.
PCT/BE2016/000028 2015-06-23 2016-06-23 Compositions et méthodes pour le traitement de biofilms Ceased WO2016205902A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB1511051.3A GB201511051D0 (en) 2015-06-23 2015-06-23 Compositions and methods for treating biofilms
GB1511051.3 2015-06-23
GBGB1511447.3A GB201511447D0 (en) 2015-06-30 2015-06-30 Compositions and methods for treating biofilms
GB1511447.7 2015-06-30

Publications (3)

Publication Number Publication Date
WO2016205902A2 WO2016205902A2 (fr) 2016-12-29
WO2016205902A3 true WO2016205902A3 (fr) 2017-02-02
WO2016205902A8 WO2016205902A8 (fr) 2017-03-30

Family

ID=56851315

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BE2016/000028 Ceased WO2016205902A2 (fr) 2015-06-23 2016-06-23 Compositions et méthodes pour le traitement de biofilms

Country Status (1)

Country Link
WO (1) WO2016205902A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202100018542A1 (it) 2021-07-14 2023-01-14 Clever Bioscience S R L Liposomi contenenti combinazioni antimicrobiche sinergiche a base di peptidi selezionati e acidi grassi
IT202100018530A1 (it) 2021-07-14 2023-01-14 Clever Bioscience S R L Composizioni antimicrobiche sinergiche contenenti peptidi selezionati e acidi grassi

Family Cites Families (20)

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US3490201A (en) 1966-08-05 1970-01-20 Oliver D Colvin Method and apparatus for drying gases
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SE365720B (fr) 1971-08-06 1974-04-01 Atlas Copco Ab
SE368662B (fr) 1972-03-10 1974-07-15 Munters Ab Carl
US4783432A (en) 1987-04-28 1988-11-08 Pall Corporation Dryer regeneration through heat of compression and pressure swing desorption
US5683532A (en) 1990-08-12 1997-11-04 Kabushiki Kaisha Seibu Giken Method of manufacturing an active silica gel honeycomb adsorbing body usable in an atmosphere having 100% relative humidity
BE1005764A3 (nl) 1992-04-15 1994-01-18 Atlas Copco Airpower Nv Inrichting voor het drogen van een gas.
DE69906370T2 (de) 1998-12-09 2003-12-18 Domnick Hunter Limited, Durham Gastrockner
AU5466400A (en) 1999-06-04 2000-12-28 Flair Corporation Rotating drum adsorber process and system
BE1013389A3 (nl) 2000-04-13 2001-12-04 Atlas Copco Airpower Nv Compressorinstallatie voorzien van een drooginrichting.
BE1013441A3 (nl) 2000-05-17 2002-01-15 Atlas Copco Airpower Nv Compressorinstallatie voorzien van een adsorptiedroger en adsorptiedroger daarvoor.
US6375722B1 (en) 2000-08-22 2002-04-23 Henderson Engineering Co., Inc. Heat of compression dryer
BE1013828A3 (nl) 2000-11-08 2002-09-03 Atlas Copco Airpower Nv Werkwijze voor het regelen van een compressorinstallatie met een droger en daarbij gebruikte compressorinstallatie.
US6957403B2 (en) 2001-03-30 2005-10-18 Syntest Technologies, Inc. Computer-aided design system to automate scan synthesis at register-transfer level
US7166149B2 (en) 2004-01-12 2007-01-23 Uop Llc Adsorption process for continuous purification of high value gas feeds
BE1016145A3 (nl) 2004-08-02 2006-04-04 Atlas Copco Airpower Nv Verbeterde compressorinrichting.
BE1016149A3 (nl) 2004-08-04 2006-04-04 Atlas Copco Airpower Nv Werkwijze voor het drogen van een gas en inrichting daarbij toegepast.
BE1016309A3 (nl) 2004-11-10 2006-07-04 Atlas Copco Airpower Nv Werkwijze voor het drogen van samengeperst gas en inrichting daarbij toegepast.
WO2007079533A1 (fr) 2006-01-10 2007-07-19 South Eastern Sydney And Illawarra Area Health Service Méthode d'établissement et de prolifération de cse humaines par culture jointe avec des cellules nourricières allogéniques dans un milieu sans sérum
EP2332631B1 (fr) 2009-12-03 2012-11-14 Kaeser Kompressoren GmbH Dispositif de séchage par adsorption ainsi que procédé de séchage par adsorption

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* Cited by examiner, † Cited by third party
Title
AN M. AERTS ET AL: "The Antifungal Plant Defensin HsAFP1 from Heuchera Sanguinea Induces Apoptosis in Candida Albicans", FRONTIERS IN MICROBIOLOGY, vol. 2, 1 January 2011 (2011-01-01), XP055309602, DOI: 10.3389/fmicb.2011.00047 *
ANA VALENTE ET AL: "Revealing the Properties of Plant Defensins through Dynamics", MOLECULES, vol. 18, no. 9, 13 September 2013 (2013-09-13), pages 11311 - 11326, XP055309768, DOI: 10.3390/molecules180911311 *
KIM VRIENS ET AL: "Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures", PLOS ONE, vol. 10, no. 8, 6 August 2015 (2015-08-06), pages e0132701, XP055309561, DOI: 10.1371/journal.pone.0132701 *
THEVISSEN ET AL: "Therapeutic potential of antifungal plant and insect defensins", DRUG DISCOVERY TODAY, ELSEVIER, RAHWAY, NJ, US, vol. 12, no. 21-22, 1 November 2007 (2007-11-01), pages 966 - 971, XP022338227, ISSN: 1359-6446, DOI: 10.1016/J.DRUDIS.2007.07.016 *
UMA SHANKAR SAGARAM ET AL: "Structure-Activity Determinants in Antifungal Plant Defensins MsDef1 and MtDef4 with Different Modes of Action against Fusarium graminearum", PLOS ONE, vol. 6, no. 4, 1 January 2011 (2011-01-01), pages e18550 - e18550, XP055063980, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0018550 *
VRIENS KIM ET AL: "The radish defensins RsAFP1 and RsAFP2 act synergistically with caspofungin againstCandida albicansbiofilms", PEPTIDES, vol. 75, 28 November 2015 (2015-11-28), pages 71 - 79, XP029380968, ISSN: 0196-9781, DOI: 10.1016/J.PEPTIDES.2015.11.001 *
YAN JIANG ET AL: "Antimicrobial activities of recombinant mouse Î-defensin 3 and its synergy with antibiotics", JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE, KLUWER ACADEMIC PUBLISHERS, BO, vol. 23, no. 7, 21 April 2012 (2012-04-21), pages 1723 - 1728, XP035076877, ISSN: 1573-4838, DOI: 10.1007/S10856-012-4645-Z *

Also Published As

Publication number Publication date
WO2016205902A8 (fr) 2017-03-30
WO2016205902A2 (fr) 2016-12-29

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