WO2017013644A2 - Lentille de contact pour une correction de la vision - Google Patents

Lentille de contact pour une correction de la vision Download PDF

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Publication number
WO2017013644A2
WO2017013644A2 PCT/IL2016/050780 IL2016050780W WO2017013644A2 WO 2017013644 A2 WO2017013644 A2 WO 2017013644A2 IL 2016050780 W IL2016050780 W IL 2016050780W WO 2017013644 A2 WO2017013644 A2 WO 2017013644A2
Authority
WO
WIPO (PCT)
Prior art keywords
lens
contact lens
cornea
regions
continuous wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2016/050780
Other languages
English (en)
Other versions
WO2017013644A3 (fr
Inventor
Yair Alster
Omer Rafaeli
Ofer Pintel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pres by Vision Ltd
Original Assignee
Pres by Vision Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pres by Vision Ltd filed Critical Pres by Vision Ltd
Publication of WO2017013644A2 publication Critical patent/WO2017013644A2/fr
Publication of WO2017013644A3 publication Critical patent/WO2017013644A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes
    • G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures

Definitions

  • the present invention relates to a lens and, more particularly, to various embodiments of a contact lens which can be used to correct vision problems such as presbyopia.
  • Typical vision problems such as myopia (nearsightedness), hyperopia (farsightedness) or presbyopia (loss of accommodation and subsequent loss of near and intermediate vision) are readily correctable using eyeglasses.
  • myopia nearsightedness
  • hyperopia farsightedness
  • presbyopia loss of accommodation and subsequent loss of near and intermediate vision
  • eyeglasses some individuals prefer contact lenses for vision correction due to an active life style or aesthetic preferences.
  • multifocal lenses which simultaneously focus light from a range of distances via several focal regions and bifocal lenses that include two simultaneously distinct lens powers, a central region for correction of myopia and a surrounding region for correction of hyperopia.
  • the latter lenses translate with respect to the optical axis of the eye to provide both near and far vision correction depending on the eye gaze angle.
  • bifocal and multifocal lenses can correct presbyopia
  • translation of the bifocal lens with respect to the cornea - anywhere from 2-6 mm (significantly more than standard contact lenses that typically translate about 0 to 0.5 mm) - can cause irritation and significant discomfort to the user while simultaneous focusing of light from several distances - as is the case for multifocal lenses - requires the user to 'process' light coming in from several distances.
  • anatomical variability with respect to the distance between the optical axis and lower lid margin necessitates individual fitting of lenses and patient adjustment to correctly align the near- vision correction region of the bifocal lens to the optical axis during near vision tasks.
  • a contact lens comprising a continuous wall surrounding an internal volume, the contact lens being capable of rolling on a surface of a cornea such that opposing regions of the continuous wall move in opposite directions with respect to each other along an axis parallel to the surface of the cornea.
  • opposing regions of the continuous wall include optical regions of different optical power.
  • the volume is filled with a fluid.
  • a first regions of the opposing regions has a first optical power and a second region of the opposing regions has a second optical power.
  • the contact lens is shaped as an oblate spheroid preferably with a concave cornea-contacting surface.
  • the continuous wall is fabricated from a hydrogel, silicone, silicone hydrogel (SH) or fluorosilicone-acrylate.
  • the oblate spheroid is 5-20 mm in diameter.
  • the oblate spheroid is has a base curve radius of 7.8- 10.0 mm.
  • an internal surface of the continuous wall is fabricated from, or coated with, hydrophobic material and the volume is filled with a hydrophilic fluid.
  • a contact lens comprising a first material less pliable than a second material, wherein an end portion of the contact lens is formed from the first material.
  • the end portion is circumferential and surrounds a central portion made from the second material.
  • the first material and the second material are silicone and the first material exhibits a lower Shore A than the second material.
  • the end portion of the contact lens has a non-zero optical power.
  • the lens is shaped so as to translate over a carrier lens when in an eye.
  • a base curvature of the end portion is different than that of the central region.
  • a cornea- contacting surface of the lens is hydrophobic.
  • the contact is fabricated from silicone hydrogel with a Modulus of 0.1 to 2.5 MPa or silicone with a Modulus of 0.27 to 8.68 MPa.
  • the present invention successfully addresses the shortcomings of the presently known configurations by providing a lens configured for correcting presbyopia while being stable and comfortable to wear and use.
  • FIGs. 1A-B illustrates the shape of the present lens prior to (FIG. 1A) and following (FIG. IB) positioning over the surface of a cornea.
  • FIG. 2 illustrates the front and back surfaces of the lens.
  • FIG. 3 illustrates the forces acting on the front and back surfaces of the lens.
  • FIGs. 4A-B illustrate one embodiment of the present lens showing opposing surfaces of the lens. Opposing walls of the lens are indicated by different shading for illustrative purposes. FIGs. 4A-B illustrate 'rolling' of lens walls and movement of opposing wall regions.
  • FIGs. 5A-B illustrate the lens of FIG. 4 when positioned over the eye during gaze forward (FIG. 5a) and gaze down (FIG. 5b). Opposing walls of the lens are indicated by different shading for illustrative purposes.
  • FIGs. 6A-6B illustrates a lens suitable for use in a two lens system for correcting vision disorders.
  • FIGs. 7A-B illustrate the lens of FIGs. 6A-6B mounted over a carrier lens under gaze forward (FIG. 7A) and gaze down (FIG. 7B) conditions.
  • the present invention is of a lens system that can be used to correct visions in hyperopic, myopic or ametropic individuals with presbyopia. Specifically, the present invention can be used to provide both near, intermediate and far vision while traversing comfort and usability problems of prior art bifocal and multifocal lenses.
  • Multifocal contact lenses as well as translating lenses (both rigid and soft) are available commercially but have not gained significant market share. Multifocal contact lens reduce vision quality while bifocal lenses require significant fitting effort and cause significant discomfort in many individuals.
  • LLM-COP Lower Lid Margin to the Center Of Pupil
  • the present inventors While reducing the present invention to practice, the present inventors have devised a single body (one continuous wall/surface) lens which can be used for correction of presbyopia.
  • the present inventors have also devised a contact lens which can be used as a piggyback lens in a two lens system for correcting presbyopia.
  • a contact lens for correction of vision disorders including presbyopia.
  • the term “lens” refers to a light-passing element.
  • the lens can be any shape and configuration and can have regions of zero, negative or positive optical power as well as cylindrical power.
  • the lens is fabricated from a continuous wall surrounding an internal volume.
  • the contact lens is configured to be capable of rolling on a surface of a cornea such that opposing regions of the continuous wall move in opposite directions with respect to each other along an axis parallel to the surface of the cornea.
  • the lens can be a collapsed sphere, e.g., an oblate spheroid-like shape with the proximal (cornea-contacting) wall being concave to match the curvature of the cornea.
  • the present inventors examined the forces on such a lens when positioned in an eye.
  • a collapsed sphere-type lens fabricated from a thin, soft material, (e.g. Silicon, Silicon Hydrogel (SH) and/or Hydrogel with total thickness ranging between 50 to 800 microns stretched over a cornea forms the dome shown in FIGs. 1A - IB.
  • the dome-shaped lens includes two domed surfaces/walls lying one on top of the other, a "front” or distal surface and a "back” or proximal surface (FIG. 2).
  • the total area of the lens which is in contact with the cornea is equal to the area of the front surface in contact with the back surface (a collapsed sphere-like lens is totally symmetric and rolls on the corneal surface as such, at any given position, the internal surface of the lens will be identical to the surface between the lens and the cornea).
  • FIG. 3 summarizes the forces acting on the lens.
  • F 2 is controllable and is a function of thickness, material, geometry and distance between walls, the latter denoted ⁇ , as:
  • F 2 f (thickness, material, geometry, ⁇ ).
  • Fi is the force of the lid on the front surface.
  • the lens has to be designed to provide ⁇ ⁇ 2 > ⁇ > ⁇ ⁇ ⁇ + ⁇ 2 .
  • the present lens is designed with the following properties:
  • Geometry and dimensions - diameter between 6-20mm, wall thickness can vary between 20-700 mm. Areas of optical power can be thinner or thicker according to corrective power desired.
  • volume - walls can be 0-1 mm apart and the volume can be 0—500 mm .
  • the volume can be filled with a non-optical fluid such as air, saline, water and the like or it can be filled with an optical fluid to provide near or far sight vision correction.
  • the lens can be provided with an optical region for additional vision correction (e.g. for correcting for near vision while the entire lens around the particular optical region provides far vision correction).
  • lens 10 One embodiment of the present lens which is referred to herein as lens 10 is shown in FIG.s 4A, 4B, 5A and 5B.
  • lens 10 is formed from a contiguous wall 12 surrounding a volume 14.
  • lens 10 is shaped as an oblate sphere with a concave back surface.
  • Lens 10 can be fabricated from silicone, silicon hydrogel, Hydrogel, RGP and the like, with a surface roughness of 20-1500Microns. When not positioned in the eye, lens 10 can be 6-20 mm in diameter and up to 1 mm in thickness. Once positioned in the eye, lens 10 can adapt to the shape of the cornea to completely or partially flatten. Lens 10 can include one or more optical regions 16 of various focusing power. Such optical regions 16 can have zero, positive or negative power depending on the use of lens 10.
  • Optical regions 16 can have an area of 3 mm 2 to 60 mm 2 and a shape and thickness suitable for the optical power desired.
  • FIGs. 5A-B illustrate lens 10 positioned over a corneal surface during gaze forward (FIG. 5A) and gaze down (FIG. 5B) showing movement of optical regions 16 and 16'.
  • a presbyopic configuration of lens 10 can include two optical regions a first optical region 16 having a positive diopter (e.g. +1 to +2.5) and a second optical region 16' having a negative diopter (e.g. -2 to -4).
  • first optical region 16 having a positive diopter e.g. +1 to +2.5
  • second optical region 16' having a negative diopter e.g. -2 to -4.
  • rolling of the lens on the corneal surface moves optical region 16' out of the optical axis and brings optical region 16 with near vision correction into the optical axis of the eye.
  • Lens 10 can include regions of higher thickness (e.g. at 16 and/or 16') that can act as 'roll stop' regions. Such regions would increase the resistance of lens 10 to roll once positioned at the 'edge' (periphery) of lens 10.
  • Lens 10 can be fabricated using well known approaches such as injection/blow molding, vacuum forming, machining and the like.
  • Coating of materials on the inner and outer surfaces of the lens can be effected using plasma deposition and the like.
  • the present inventors have also devised a lens suitable for use in a two lens system for correcting vision disorders and in particular presbyopia.
  • a contact lens which includes an end portion formed from a first material which is less pliable than a second material forming a non-end portion of the lens.
  • FIGs. 6A, 6B, 7A and 7B illustrate one embodiment of such a lens which is referred to herein as lens 50.
  • Lens 50 includes a central portion 54 formed from the second material surrounded by a ring-like end portion 56 formed from the first material (FIG. 6A).
  • FIG. 6 illustrates lens 50 when out of the eye (carrier lens 52 shown in FIG. 6B)
  • FIGs. 7A-B illustrate lens 50 mounted over carrier lens 52 during gaze forward (FIG. 7A) and gaze down (FIG. 7B).
  • Lens 50 is sized and configured to efficiently translate over carrier lens 52 (preferably a hydrophilic lens fabricated from Silicon hydrogel/Hydrogel or the like) without appreciable movement of carrier lens 52 over cornea or displacement/detachment of lens 50 from carrier lens 52.
  • carrier lens 52 preferably a hydrophilic lens fabricated from Silicon hydrogel/Hydrogel or the like
  • Such efficient translation is a function of both lens configuration (less pliable lens 50 edge or periphery) and the front surface of lens 52 and back surface of lens 50, and in particular, the back surface of central portion 54.
  • Lens 50 is 6-15 mm in diameter with a radius of curvature of 7-9 mm.
  • Several approaches can be used to make end portion 56 of lens 50 less pliable than central portion 54. Such approaches do not employ variable thickness but rather use of different materials and durometer.
  • lens 50 can be fabricated from silicon Hydrogel (SH) with Modulus values ranging from 0.1 to 1.9 MPa (with central portion 54 having a lower MPa value than end portion 56, e.g. 0.5 MPa for central portion 54 and 1.5 MPa for end portion 56) or from Silicone having a Shore A value of 20 to 80 (between 2.0 MPa to 9.7 MPa) with central portion 54 having a lower Shore A value than end portion 56 [e.g. Shore A value of 20 for central portion 54 and Shore A value of 50 for end portion 56].
  • SH silicon Hydrogel
  • Modulus values ranging from 0.1 to 1.9 MPa (with central portion 54 having a lower MPa value than end portion 56, e.g. 0.5 MPa for central portion 54 and 1.5 MP
  • portion 54 can also be provided via one or more holes or a pattern of openings.
  • portion 54 can include a single central hole that covers at some or all of the area of portion 54.
  • central portion 54 The pliability of central portion 54 is selected such that it adapts (conforms with) the front curvature of carrier lens 52. Since the friction between hydrophilic and hydrophobic surfaces is lower than the friction between carrier lens 52 and the cornea, lens 50 will translate on carrier lens 52 which will remain relatively stationary on the cornea.
  • Lens 50 can include a lid engagement element 58 for engaging a lower lid 60.
  • Lid engagement element 58 can be a protrusion on the external surface of lens 50. Such a protrusion can be wedged shaped with a height (maximum) of 0.1-1 mm.
  • Lens 50 is designed to fit any type of carrier lens 52 including, for example, an off the shelf SH/Hydrogel spherical non-spherical or cylindrical lens. Lens 50 does not interfere with the optical correction of carrier lens 52 when mounted thereupon, e.g. when lens 50 is mounted on lens 52, the optical power region of lens 50 does not reside within the optical power region of lens 52 during gaze forward (e.g. central region 54 of lens 50 does not have any optical power).
  • the base curve and geometry of lens 50 are selected so as to form and maintain adhesion between lenses 50 and 52 during gaze forward and gaze down and translation between these two states.
  • a lens 50 with a base curve (BC) of 8.0 will 'float' (and thus will be less stable) over a carrier lens 52 having a front surface with a BC of 7.5 mm; a lens 50 with a BC of 7.0 mm will be more stable over such a carrier lens 52 with increased resistance to translation.
  • the more pliable central portion 54 will adapt its central radius to that of the front curve of carrier lens 52 and thus form strong adhesion therewith.
  • the less pliable edge portion 56 will include region(s) of optical power and variable thickness and a base curve that can be different than that of central portion 54. Due to its lower pliability (higher rigidity) and a base curve that does not match that of carrier lens 52, edge portion 56 will not conform well to the front curvature of lens 52. As a result, adhesion forces between lens 52 and 50 will be lower and the gap therebetween will enable fluid to flow between lens 50 and lens 52.

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Eyeglasses (AREA)

Abstract

L'invention concerne un système de lentille de contact. Ledit système comprend une première lentille conçue pour être positionnée sur la cornée et une seconde lentille qui peut être positionnée au-dessus de la première lentille. Le système est conçu de telle sorte que la résistance au mouvement latéral de la première lentille par rapport à la cornée est supérieur à la résistance au mouvement latéral de la seconde lentille par rapport à la première lentille.
PCT/IL2016/050780 2015-07-22 2016-07-17 Lentille de contact pour une correction de la vision Ceased WO2017013644A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562195497P 2015-07-22 2015-07-22
US62/195,497 2015-07-22

Publications (2)

Publication Number Publication Date
WO2017013644A2 true WO2017013644A2 (fr) 2017-01-26
WO2017013644A3 WO2017013644A3 (fr) 2017-05-18

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2016/050780 Ceased WO2017013644A2 (fr) 2015-07-22 2016-07-17 Lentille de contact pour une correction de la vision

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Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2720824B1 (fr) * 1994-06-02 1997-01-24 Macofar Spa Procédé pour le contrôle en ligne du poids de capsules et appareil relatif.
JP2000226016A (ja) * 1999-02-03 2000-08-15 Shionogi Qualicaps Kk 不良カプセルの除去機構
AUPR276601A0 (en) * 2001-01-31 2001-02-22 Newman, Steve A contact lens for refractive correction and capable of engagement with an eye either inside out or right way out
US7699464B2 (en) * 2006-01-05 2010-04-20 In Technology Holdings Llc Hydrodynamically operated multifocal contact lens

Also Published As

Publication number Publication date
WO2017013644A3 (fr) 2017-05-18

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