WO2024254478A3 - Microbis pour inhibition bactérienne - Google Patents

Microbis pour inhibition bactérienne Download PDF

Info

Publication number
WO2024254478A3
WO2024254478A3 PCT/US2024/033048 US2024033048W WO2024254478A3 WO 2024254478 A3 WO2024254478 A3 WO 2024254478A3 US 2024033048 W US2024033048 W US 2024033048W WO 2024254478 A3 WO2024254478 A3 WO 2024254478A3
Authority
WO
WIPO (PCT)
Prior art keywords
nrrl
strains
microbials
relates
bacterial inhibition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2024/033048
Other languages
English (en)
Other versions
WO2024254478A2 (fr
Inventor
Sona SON
Michael R. King
Jessica EDWARD
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Discovery Group LLC
Original Assignee
Microbial Discovery Group LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Discovery Group LLC filed Critical Microbial Discovery Group LLC
Priority to CN202480042253.7A priority Critical patent/CN121712518A/zh
Publication of WO2024254478A2 publication Critical patent/WO2024254478A2/fr
Publication of WO2024254478A3 publication Critical patent/WO2024254478A3/fr
Priority to MX2025014302A priority patent/MX2025014302A/es
Anticipated expiration legal-status Critical
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/30Feeding-stuffs specially adapted for particular animals for swines
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/70Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75Feeding-stuffs specially adapted for particular animals for birds for poultry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07Bacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Husbandry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Fodder In General (AREA)

Abstract

La présente invention concerne des microbes d'alimentation directe destinés à être utilisés dans l'inhibition d'E. coli, de Salmonell, et/ou de Clostridium chez l'animal. Plus particulièrement, l'invention concerne des souches isolées de Bacillus CM256 (NRRL N° B-67706), CM857 (NRRL N° B-67705), CM978 (NRRL N° B-67703), CM1004 (NRRL N° B-67708) et MDG1607 (NRRL N° B-67666), ainsi que des souches possédant toutes les caractéristiques d'identification de ces souches, pour une utilisation comprenant l'utilisation susmentionnée. L'invention concerne également l'utilisation de souches isolées de Bacillus CM256 (NRRL N° B-67706), CM857 (NRRL N° B-67705), CM978 (NRRL N° B-67703) et CM1004 (NRRL N° B-67708), ainsi que des souches possédant toutes les caractéristiques d'identification de ces souches, pour traiter des plantes atteintes de maladies provoquées par E. coli, Salmonella et/ou Clostridium .<u />
PCT/US2024/033048 2023-06-08 2024-06-07 Microbis pour inhibition bactérienne Pending WO2024254478A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202480042253.7A CN121712518A (zh) 2023-06-08 2024-06-07 用于细菌抑制的微生物
MX2025014302A MX2025014302A (es) 2023-06-08 2025-11-28 Microbianos para la inhibicion bacteriana

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363506993P 2023-06-08 2023-06-08
US63/506,993 2023-06-08

Publications (2)

Publication Number Publication Date
WO2024254478A2 WO2024254478A2 (fr) 2024-12-12
WO2024254478A3 true WO2024254478A3 (fr) 2025-05-08

Family

ID=93794619

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2024/033048 Pending WO2024254478A2 (fr) 2023-06-08 2024-06-07 Microbis pour inhibition bactérienne

Country Status (3)

Country Link
CN (1) CN121712518A (fr)
MX (1) MX2025014302A (fr)
WO (1) WO2024254478A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100093860A1 (en) * 2006-05-01 2010-04-15 University Gent Hydroxybutyrate and poly-hydroxybutyrate as components of animal feed or feed additives
US20200276279A1 (en) * 2011-02-18 2020-09-03 Dupont Nutrition Biosciences Aps Feed additive composition
US20210236563A1 (en) * 2018-05-01 2021-08-05 Microbial Discovery Group, Llc Microbials for feed

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100093860A1 (en) * 2006-05-01 2010-04-15 University Gent Hydroxybutyrate and poly-hydroxybutyrate as components of animal feed or feed additives
US20200276279A1 (en) * 2011-02-18 2020-09-03 Dupont Nutrition Biosciences Aps Feed additive composition
US20210236563A1 (en) * 2018-05-01 2021-08-05 Microbial Discovery Group, Llc Microbials for feed

Also Published As

Publication number Publication date
WO2024254478A2 (fr) 2024-12-12
CN121712518A (zh) 2026-03-20
MX2025014302A (es) 2026-01-07

Similar Documents

Publication Publication Date Title
KR100437497B1 (ko) 로타바이러스 및 유해 미생물 억제 활성을 가지는 신규내산성 락토바실러스 루테리 프로바이오-16 및 이를함유하는 생균활성제
Svetoch et al. Isolation of Bacillus circulans and Paenibacillus polymyxa strains inhibitory to Campylobacter jejuni and characterization of associated bacteriocins
US6251461B1 (en) Antimicrobial activity of hops extract against Clostridium botulinum, Clostridium difficile and Helicobacter pylori
Barefoot et al. Identification and purification of a protein that induces production of the Lactobacillus acidophilus bacteriocin lactacin B
WO2001013927A3 (fr) Compositions topiques ameliorees contenant des bacteries probiotiques, des spores et des produits extra-cellulaires et leur utilisation
Gao et al. Garviecin LG34, a novel bacteriocin produced by Lactococcus garvieae isolated from traditional Chinese fermented cucumber
WO2020074547A8 (fr) Souches probiotiques de lactobacillus crispatus appropriées pour le traitement de levures urogénitales et d&#39;infections bactériennes
Pereira et al. Isolation of three novel Antarctic psychrotolerant feather-degrading bacteria and partial purification of keratinolytic enzyme from Lysobacter sp. A03
KR101498272B1 (ko) 김치에서 분리되고 항균물질생성 및 면역활성 효능을 가진 바실러스 서브틸리스 균주 및 이를 이용한 생균제 조성물
Gao et al. Purification and characteristics of a novel bacteriocin produced by Enterococcus faecalis L11 isolated from Chinese traditional fermented cucumber
Upadhyay et al. Pseudomonas cepacia causes mycelial deformities and inhibition of conidiation in phytopathogenic fungi
RU2020132317A (ru) Применение микробных препаратов для приема в пищу в предупреждении и/или лечении инфекций, опосредованных e. coli, у животных
ES553227A0 (es) Un procedimiento para preparar derivados monoamidicos basicos de actagardina
WO2024254478A3 (fr) Microbis pour inhibition bactérienne
KR20160107635A (ko) 제한된 항균작용을 갖는 박테리오신 생산 락토바실러스 람노서스 cjnu 0519 및 이의 용도
AU740898B1 (en) Antimicrobial agent against acid-resistant and heat-resistant bacteria
Ceccoli et al. Polyclonal antibodies against O6-methylguanine-DNA methyltransferase in adapted bacteria
Upadhyay Growth and bacteriolytic activity of a soil amoeba, Hartmannella glebae
KR102445675B1 (ko) 신규한 바실러스 서브틸리스 균주 및 이를 이용하여 발효한 생강의 기능성
Jagadeesan et al. Assessment of synthesis machinery of two antimicrobial peptides from Paenibacillus alvei NP75
Venturina et al. Isolation and identification of subtilosin A-producing Bacillus subtilis from mongo sprouts, silage and soil samples in the Philippines
Oladipo et al. Bioprotective potential of bacteriocinogenic Enterococcus gallinarum strains isolated from some Nigerian fermented foods, and of their bacteriocins
MX2025012250A (es) Composiciones microbianas para inhibir fusobacterium o trueperella
Kim et al. Antimicrobial and antioxidant peptide from Bacillus strain CBS73 isolated from Korean Food
MX2023002033A (es) Microbios y antibioticos.

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: MX/A/2025/014302

Country of ref document: MX

REG Reference to national code

Ref country code: BR

Ref legal event code: B01A

Ref document number: 112025026421

Country of ref document: BR

WWP Wipo information: published in national office

Ref document number: MX/A/2025/014302

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 2024820147

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2024820147

Country of ref document: EP

Effective date: 20260108

ENP Entry into the national phase

Ref document number: 2024820147

Country of ref document: EP

Effective date: 20260108

ENP Entry into the national phase

Ref document number: 2024820147

Country of ref document: EP

Effective date: 20260108

ENP Entry into the national phase

Ref document number: 2024820147

Country of ref document: EP

Effective date: 20260108

ENP Entry into the national phase

Ref document number: 2024820147

Country of ref document: EP

Effective date: 20260108

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 24820147

Country of ref document: EP

Kind code of ref document: A2