YU104191A - Supstituisani benzimidazoli i postupak za njihovo dobijanje - Google Patents

Supstituisani benzimidazoli i postupak za njihovo dobijanje

Info

Publication number: YU104191A
Authority: YU; Yugoslavia
Prior art keywords: carbon atoms; substituted benzimidazoles; procedure; obtaining; alkyl containing
Prior art date: 1990-06-20

Application number

YU104191A

Other languages

English (en)

Serbo-Croatian (sh)

Inventor

A.E. Braendstroem

P.L. Lindberg

G.E. Sinnden

Original Assignee

Aktiebolaget Astra

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-20

Filing date

1991-06-12

Publication date

1994-01-20

1991-06-12 Application filed by Aktiebolaget Astra filed Critical Aktiebolaget Astra

1994-01-20 Publication of YU104191A publication Critical patent/YU104191A/sh

Links

150000001556 benzimidazoles Chemical class 0.000 title abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)

YU104191A 1990-06-20 1991-06-12 Supstituisani benzimidazoli i postupak za njihovo dobijanje YU104191A (sh)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9002206A SE9002206D0 (sv)	1990-06-20	1990-06-20	New compounds

Publications (1)

Publication Number	Publication Date
YU104191A true YU104191A (sh)	1994-01-20

Family

ID=20379831

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU104191A YU104191A (sh)	1990-06-20	1991-06-12	Supstituisani benzimidazoli i postupak za njihovo dobijanje

Country Status (27)

Country	Link
EP (1)	EP0535081A1 (is)
JP (1)	JPH05507713A (is)
CN (1)	CN1058212A (is)
AP (1)	AP215A (is)
AU (1)	AU649453B2 (is)
BG (1)	BG97200A (is)
CA (1)	CA2083714A1 (is)
CZ (1)	CZ279772B6 (is)
FI (1)	FI925766A0 (is)
HU (1)	HUT62881A (is)
IE (1)	IE912025A1 (is)
IL (1)	IL98470A0 (is)
IS (1)	IS3721A7 (is)
LT (2)	LT3977B (is)
LV (1)	LV10953A (is)
MA (1)	MA22199A1 (is)
NO (1)	NO924775L (is)
NZ (1)	NZ238546A (is)
OA (1)	OA09682A (is)
PT (1)	PT98035A (is)
RO (1)	RO110493B1 (is)
SE (1)	SE9002206D0 (is)
TN (1)	TNSN91049A1 (is)
TW (1)	TW216418B (is)
WO (1)	WO1991019711A1 (is)
YU (1)	YU104191A (is)
ZA (2)	ZA914297B (is)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9002043D0 (sv) *	1990-06-07	1990-06-07	Astra Ab	Improved method for synthesis
SE9103776D0 (sv) *	1991-12-19	1991-12-19	Astra Ab	New compounds
IS4232A (is) *	1993-12-06	1995-06-07	Astra Aktiebolag	Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun
SE504459C2 (sv) *	1994-07-15	1997-02-17	Astra Ab	Förfarande för framställning av substituerade sulfoxider
SE9500422D0 (sv) *	1995-02-06	1995-02-06	Astra Ab	New oral pharmaceutical dosage forms
SE9500478D0 (sv) *	1995-02-09	1995-02-09	Astra Ab	New pharmaceutical formulation and process
SE9600070D0 (sv)	1996-01-08	1996-01-08	Astra Ab	New oral pharmaceutical dosage forms
AU5424500A (en)	2000-02-24	2001-09-03	Kopran Res Lab Ltd	Orally administrable acid stable anti-ulcer benzimidazole derivatives
SE0101379D0 (sv)	2001-04-18	2001-04-18	Diabact Ab	Komposition som hämmar utsöndring av magsyra
US8206741B2 (en)	2001-06-01	2012-06-26	Pozen Inc.	Pharmaceutical compositions for the coordinated delivery of NSAIDs
MXPA04009968A (es)	2002-04-09	2004-12-13	Flamel Tech Sa	Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de principio (s) activo (s).
SE0203065D0 (sv)	2002-10-16	2002-10-16	Diabact Ab	Gastric acid secretion inhibiting composition
US8246986B2 (en)	2003-09-26	2012-08-21	Alza Corporation	Drug coating providing high drug loading
TW200606163A (en)	2004-04-22	2006-02-16	Eisai Co Ltd	Imidazopyridine compound
US8541026B2 (en)	2004-09-24	2013-09-24	Abbvie Inc.	Sustained release formulations of opioid and nonopioid analgesics
US20070015782A1 (en)	2005-04-15	2007-01-18	Eisai Co., Ltd.	Benzimidazole compound
US9040564B2 (en)	2005-04-28	2015-05-26	Eisai R&D Management Co., Ltd.	Stabilized composition
US7803817B2 (en)	2005-05-11	2010-09-28	Vecta, Ltd.	Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en)	2005-05-11	2011-07-19	Vecta, Ltd.	Compositions and methods for inhibiting gastric acid secretion
WO2007122686A1 (ja) *	2006-04-14	2007-11-01	Eisai R & D Management Co., Ltd.	ベンズイミダゾール化合物
US9233092B2 (en)	2006-07-25	2016-01-12	Vecta, Ltd.	Compositions and methods for inhibiting gastric acid secretion using derivatives of small dicarboxylic acids in combination with PPI
EP2065379A4 (en) *	2006-10-13	2011-01-19	Eisai R&D Man Co Ltd	BENZIMIDAZOLE HAVING INHIBITORY ACTIVITY OF GASTRIC ACID SECRETION
EA201100313A1 (ru)	2008-09-09	2011-10-31	Астразенека Аб	Способ доставки фармацевтической композиции пациенту, нуждающемуся в этом
CA2764963C (en)	2009-06-25	2016-11-01	Astrazeneca Ab	Method for treating a patient at risk for developing an nsaid-associated ulcer
WO2011080501A2 (en)	2009-12-29	2011-07-07	Orexo Ab	New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080502A2 (en)	2009-12-29	2011-07-07	Orexo Ab	New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080500A2 (en)	2009-12-29	2011-07-07	Orexo Ab	New pharmaceutical dosage form for the treatment of gastric acid-related disorders
EP2601947A1 (en)	2011-12-05	2013-06-12	Abo Bakr Mohammed Ali Al-Mehdar	Fixed-dose combination for treatment of helicobacter pylori associated diseases
BR112014016085A8 (pt)	2011-12-28	2017-07-04	Pozen Inc	composições aprimoradas e métodos para distribuição de omeprazol mais ácido acetilsalicílico
CA3036250C (en)	2016-09-14	2023-09-26	Yufeng Jane Tseng	Novel substituted benzimidazole derivatives as d-amino acid oxidase (daao) inhibitors

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE418966B (sv)	1974-02-18	1981-07-06	Haessle Ab	Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv)	1974-05-16	1981-01-26	Haessle Ab	Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (is)	1977-09-19	1981-07-25	Hoffmann La Roche
SE7804231L (sv)	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
US4359465A (en)	1980-07-28	1982-11-16	The Upjohn Company	Methods for treating gastrointestinal inflammation
CH644116A5 (de)	1980-08-21	1984-07-13	Hoffmann La Roche	Imidazolderivate.
SE8300736D0 (sv)	1983-02-11	1983-02-11	Haessle Ab	Novel pharmacologically active compounds
SE8301182D0 (sv)	1983-03-04	1983-03-04	Haessle Ab	Novel compounds
IL75400A (en) *	1984-06-16	1988-10-31	Byk Gulden Lomberg Chem Fab	Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
AU568441B2 (en) *	1984-09-24	1987-12-24	Upjohn Company, The	2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) *	1984-10-31	1988-08-31	Byk Gulden Lomberg Chem Fab	Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US4738975A (en)	1985-07-02	1988-04-19	Takeda Chemical Industries, Ltd.	Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) *	1985-10-29	1985-10-29	Haessle Ab	Novel pharmacological compounds
NZ234564A (en)	1986-11-21	1991-04-26	Haessle Ab	1-substituted benzimidazoles and pharmaceutical compositions
DE3722810A1 (de) *	1987-07-10	1989-01-19	Hoechst Ag	Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
WO1989003829A1 (en) *	1987-10-30	1989-05-05	Aktiebolaget Hässle	Omeprazole for treatment of diseases related to bone loss
WO1989005299A1 (fr) *	1987-12-11	1989-06-15	Byk Gulden Lomberg Chemische Fabrik Gmbh	Nouveaux derives benzoglyoxaline
WO1989011479A1 (fr) *	1988-05-25	1989-11-30	Byk Gulden Lomberg Chemische Fabrik Gmbh	Nouveaux composes fluores d'alkoxyde

1990
- 1990-06-20 SE SE9002206A patent/SE9002206D0/xx unknown
1991
- 1991-06-05 ZA ZA914297A patent/ZA914297B/xx unknown
- 1991-06-05 ZA ZA914296A patent/ZA914296B/xx unknown
- 1991-06-11 HU HU924033A patent/HUT62881A/hu unknown
- 1991-06-11 WO PCT/SE1991/000415 patent/WO1991019711A1/en not_active Ceased
- 1991-06-11 EP EP91911659A patent/EP0535081A1/en not_active Withdrawn
- 1991-06-11 JP JP91511435A patent/JPH05507713A/ja active Pending
- 1991-06-11 CA CA002083714A patent/CA2083714A1/en not_active Abandoned
- 1991-06-11 RO RO92-01581A patent/RO110493B1/ro unknown
- 1991-06-11 AU AU80097/91A patent/AU649453B2/en not_active Ceased
- 1991-06-12 TW TW080104582A patent/TW216418B/zh active
- 1991-06-12 IL IL98470A patent/IL98470A0/xx unknown
- 1991-06-12 YU YU104191A patent/YU104191A/sh unknown
- 1991-06-14 NZ NZ238546A patent/NZ238546A/en unknown
- 1991-06-14 IE IE202591A patent/IE912025A1/en unknown
- 1991-06-18 MA MA22462A patent/MA22199A1/fr unknown
- 1991-06-19 PT PT98035A patent/PT98035A/pt not_active Application Discontinuation
- 1991-06-19 AP APAP/P/1991/000285A patent/AP215A/en active
- 1991-06-19 TN TNTNSN91049A patent/TNSN91049A1/fr unknown
- 1991-06-20 CZ CS911894A patent/CZ279772B6/cs unknown
- 1991-06-20 IS IS3721A patent/IS3721A7/is unknown
- 1991-06-20 CN CN91105024A patent/CN1058212A/zh active Pending
1992
- 1992-11-27 OA OA60306A patent/OA09682A/en unknown
- 1992-12-10 NO NO92924775A patent/NO924775L/no unknown
- 1992-12-18 FI FI925766A patent/FI925766A0/fi not_active Application Discontinuation
- 1992-12-18 BG BG097200A patent/BG97200A/bg unknown
1993
- 1993-08-27 LV LV931045A patent/LV10953A/xx unknown
- 1993-12-30 LT LTIP1713A patent/LT3977B/lt not_active IP Right Cessation
- 1993-12-30 LT LTIP1712A patent/LT3952B/lt not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI925766A7 (fi)	1992-12-18
TNSN91049A1 (fr)	1992-10-25
BG97200A (bg)	1993-12-24
OA09682A (en)	1993-05-15
EP0535081A1 (en)	1993-04-07
LV10953A (lv)	1995-12-20
AU649453B2 (en)	1994-05-26
CS189491A3 (en)	1992-04-15
IE912025A1 (en)	1992-01-01
IL98470A0 (en)	1992-07-15
WO1991019711A1 (en)	1991-12-26
HUT62881A (en)	1993-06-28
LTIP1712A (en)	1995-08-25
LT3952B (en)	1996-05-27
PT98035A (pt)	1992-03-31
AP215A (en)	1992-09-02
CA2083714A1 (en)	1991-12-21
HU9204033D0 (en)	1993-03-29
SE9002206D0 (sv)	1990-06-20
ZA914296B (en)	1992-03-25
NO924775D0 (no)	1992-12-10
RO110493B1 (ro)	1996-01-30
JPH05507713A (ja)	1993-11-04
CZ279772B6 (cs)	1995-06-14
ZA914297B (en)	1992-03-25
IS3721A7 (is)	1991-12-21
FI925766A0 (fi)	1992-12-18
CN1058212A (zh)	1992-01-29
NZ238546A (en)	1994-03-25
AU8009791A (en)	1992-01-07
MA22199A1 (fr)	1992-04-01
LT3977B (en)	1996-06-25
LTIP1713A (en)	1995-08-25
NO924775L (no)	1992-12-10
TW216418B (is)	1993-11-21
AP9100285A0 (en)	1991-07-31

Publication	Publication Date	Title
TW234116B (en)	1994-11-11	2-Cyano-3-hydroxy-enamides and their preparation process
YU36998A (sh)	1999-09-27	Derivati supstituisane 4-hidroksi-fenilalkanske kiseline sa dejstvom agonista na ppar gama
YU64092A (sh)	1995-03-27	Fluoralkoksibenzamino derivati heterocikličnih jedinjenja koja sadrže azot
YU24792A (sh)	1994-09-09	Novi amidi ugljene kiseline
YU48714B (sh)	1999-07-28	Derivati benzofurana, benzotiofena, indola i indolizina i postupak za njihovo dobijanje
SE9002206D0 (sv)	1990-06-20	New compounds
ATE126517T1 (de)	1995-09-15	Verwendung von bis(3,4- dialkylbenzyliden)sorbitolacetale und diese enthaltende zusammensetzungen.
YU47116B (sh)	1994-12-28	Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata
YU30492A (sh)	1994-12-28	Derivati piperidina i postupci za njihovo dobijanje
EA199800987A1 (ru)	1999-06-24	Бензоксазиноновые антагонисты рецептора допамина d4
CS327391A3 (en)	1992-05-13	Novel 3-cycloalkylpropaneamides, their tautomeric forms and their salts, process of their preparation and their application as medicaments and compositions containing said 3-cycloalkylpropaneamides
FI834730A0 (fi)	1983-12-22	1-karboxialkanoylperhydro-indol-2-karboxylsyror och deras derivat
DE69319925D1 (de)	1998-08-27	Indol-piperazin-derivate als selektive liganden der 5ht1d und 5ht1b receptoren verwendbar als arzneimittel
US4129727A (en)	1978-12-12	9-Deoxy-9-methylene-PGF1 -pyrrolidylamides
YU45597B (sh)	1992-07-20	Postupak za dobijanje histaminskih h (index 2)-antagonista
ES2070623T3 (es)	1995-06-01	Oxisulfonilureas inhibidoras de acat.
ES485153A1 (es)	1980-05-16	Procedimiento para la obtencion de 6-arilpiridazin-3-onas
YU44592A (sh)	1994-12-28	Derivati 4-aril-3-(heteroarilkarbamido) hinolina
FI923492A0 (fi)	1992-08-03	Indolderivat, deras framstaellning och anvaendning.
ES8407059A1 (es)	1984-09-01	Procedimiento para la preparacion de un nuevo derivado del pirrolo ortocondensado
DE69316392D1 (de)	1998-02-19	Azanoradamantane
ATE215083T1 (de)	2002-04-15	Bicyclische carboxamide als 5-ht1a rezeptoren liganden
ES467861A1 (es)	1978-10-16	Procedimiento de preparacion de espiro-oxazolidinas esteroi-des y sus esteroisomeros.
ES442441A1 (es)	1977-04-01	Procedimiento para preparar derivados de oxatinino (1,4) (2,3-c) pirrol.
ES8707204A1 (es)	1987-07-16	Procedimiento para preparar diazepinoindoles