YU28700A - Upotreba potencijatora osetljivosti na insulin u proizvodnji leka za lečenje hiperglikemije - Google Patents

Upotreba potencijatora osetljivosti na insulin u proizvodnji leka za lečenje hiperglikemije

Info

Publication number: YU28700A
Authority: YU; Yugoslavia
Prior art keywords: hyperglycaemia; treatment; thiazolidinediones; mammal; pharmaceutically acceptable
Prior art date: 1997-10-13

Application number

YU28700A

Other languages

English (en)

Serbo-Croatian (sh)

Inventor

Robin Edwin Buckingham

Stephen Alistair Smith

Original Assignee

Smithkline Beecham P.L.C.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-13

Filing date

1998-10-12

Publication date

2003-10-31

1998-10-12 Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.

2003-10-31 Publication of YU28700A publication Critical patent/YU28700A/sh

Links

201000001421 hyperglycemia Diseases 0.000 title abstract 2
229940123464 Thiazolidinedione Drugs 0.000 title 1
150000001467 thiazolidinediones Chemical class 0.000 title 1
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
231100000489 sensitizer Toxicity 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
Emergency Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

YU28700A 1997-10-13 1998-10-12 Upotreba potencijatora osetljivosti na insulin u proizvodnji leka za lečenje hiperglikemije YU28700A (sh)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9721692.3A GB9721692D0 (en)	1997-10-13	1997-10-13	Novel treatment

Publications (1)

Publication Number	Publication Date
YU28700A true YU28700A (sh)	2003-10-31

Family

ID=10820481

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU28700A YU28700A (sh)	1997-10-13	1998-10-12	Upotreba potencijatora osetljivosti na insulin u proizvodnji leka za lečenje hiperglikemije

Country Status (24)

Country	Link
EP (1)	EP1023057A1 (cs)
JP (1)	JP2001519383A (cs)
KR (1)	KR20010024482A (cs)
CN (1)	CN1281358A (cs)
AP (1)	AP1223A (cs)
AU (1)	AU9547198A (cs)
BG (1)	BG104405A (cs)
BR (1)	BR9815220A (cs)
CA (1)	CA2305289A1 (cs)
CZ (1)	CZ20001298A3 (cs)
EA (1)	EA200000418A1 (cs)
GB (1)	GB9721692D0 (cs)
HR (1)	HRP20000256A2 (cs)
HU (1)	HUP0003673A3 (cs)
ID (1)	ID24439A (cs)
IL (1)	IL135515A0 (cs)
NO (1)	NO20001897L (cs)
OA (1)	OA11519A (cs)
PL (1)	PL339804A1 (cs)
SK (1)	SK5322000A3 (cs)
TR (1)	TR200000957T2 (cs)
UA (1)	UA66809C2 (cs)
WO (1)	WO1999018944A1 (cs)
YU (1)	YU28700A (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7045519B2 (en)	1998-06-19	2006-05-16	Chiron Corporation	Inhibitors of glycogen synthase kinase 3
AP2001002036A0 (en) *	1998-07-21	2001-03-31	Smithkline Beecham Plc	Use of glucose uptake enhancer for reducing apoptosis.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0842925A1 (en) *	1987-09-04	1998-05-20	Beecham Group Plc	Substituted thiazolidinedione derivatives
GB9218830D0 (en) *	1992-09-05	1992-10-21	Smithkline Beecham Plc	Novel compounds
US5478852C1 (en) *	1993-09-15	2001-03-13	Sankyo Co	Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus

1997
- 1997-10-13 GB GBGB9721692.3A patent/GB9721692D0/en not_active Ceased
1998
- 1998-10-12 HU HU0003673A patent/HUP0003673A3/hu unknown
- 1998-10-12 UA UA2000042049A patent/UA66809C2/uk unknown
- 1998-10-12 KR KR1020007003935A patent/KR20010024482A/ko not_active Ceased
- 1998-10-12 AU AU95471/98A patent/AU9547198A/en not_active Abandoned
- 1998-10-12 YU YU28700A patent/YU28700A/sh unknown
- 1998-10-12 ID IDW20000670A patent/ID24439A/id unknown
- 1998-10-12 CZ CZ20001298A patent/CZ20001298A3/cs unknown
- 1998-10-12 CN CN98812016A patent/CN1281358A/zh active Pending
- 1998-10-12 CA CA002305289A patent/CA2305289A1/en not_active Abandoned
- 1998-10-12 TR TR2000/00957T patent/TR200000957T2/xx unknown
- 1998-10-12 WO PCT/GB1998/003067 patent/WO1999018944A1/en not_active Ceased
- 1998-10-12 AP APAP/P/2000/001788A patent/AP1223A/en active
- 1998-10-12 PL PL98339804A patent/PL339804A1/xx unknown
- 1998-10-12 IL IL13551598A patent/IL135515A0/xx unknown
- 1998-10-12 EA EA200000418A patent/EA200000418A1/ru unknown
- 1998-10-12 OA OA1200000107A patent/OA11519A/en unknown
- 1998-10-12 EP EP98949088A patent/EP1023057A1/en not_active Withdrawn
- 1998-10-12 SK SK532-2000A patent/SK5322000A3/sk unknown
- 1998-10-12 BR BR9815220-3A patent/BR9815220A/pt not_active Application Discontinuation
- 1998-10-12 JP JP2000515579A patent/JP2001519383A/ja active Pending
- 1998-10-12 HR HR20000256A patent/HRP20000256A2/hr not_active Application Discontinuation
2000
- 2000-04-12 NO NO20001897A patent/NO20001897L/no not_active Application Discontinuation
- 2000-05-05 BG BG104405A patent/BG104405A/xx unknown

Also Published As

Publication number	Publication date
EA200000418A1 (ru)	2000-10-30
BR9815220A (pt)	2000-11-14
GB9721692D0 (en)	1997-12-10
CA2305289A1 (en)	1999-04-22
NO20001897L (no)	2000-06-09
HUP0003673A2 (hu)	2001-10-28
TR200000957T2 (tr)	2000-08-21
CZ20001298A3 (cs)	2001-08-15
HUP0003673A3 (en)	2001-12-28
AP2000001788A0 (en)	2000-06-30
BG104405A (en)	2000-12-29
PL339804A1 (en)	2001-01-02
NO20001897D0 (no)	2000-04-12
OA11519A (en)	2004-02-09
AP1223A (en)	2003-11-13
HRP20000256A2 (en)	2000-12-31
AU9547198A (en)	1999-05-03
SK5322000A3 (en)	2000-09-12
KR20010024482A (ko)	2001-03-26
JP2001519383A (ja)	2001-10-23
WO1999018944A1 (en)	1999-04-22
EP1023057A1 (en)	2000-08-02
ID24439A (id)	2000-07-20
UA66809C2 (uk)	2004-06-15
IL135515A0 (en)	2001-05-20
CN1281358A (zh)	2001-01-24

Publication	Publication Date	Title
EP1787646A3 (en)	2007-10-03	Novel method of treatment
PL325825A1 (en)	1998-08-03	Microemulsion for use as a carrier for administering active compounds
MY124695A (en)	2006-06-30	Novel composition and use.
EP1127579A3 (en)	2004-01-21	Method for increasing bioavailability of oral pharmaceutical compositions
AU3215597A (en)	1998-03-19	Method of inhibiting fibrosis with a somatostatin agonist
CA2352552A1 (en)	1991-10-26	Treatment of erectile dysfunction
CA2339218A1 (en)	2000-02-17	Methods and compositions for increasing insulin sensitivity
WO1999004772A3 (en)	1999-04-08	Use of levobupivacaine
MY106528A (en)	1995-06-30	Method of treating impotence.
MY155219A (en)	2015-09-30	Treatment of diabetes with thiazolidinedione, insulin secretagogue and biguanide
BG104059A (en)	2000-10-31	Diabetes treatment with rosiglytazone and insulin
CA2190837A1 (en)	1995-11-30	Transdermal delivery of anti-epileptic drugs
EP1561462A3 (en)	2005-08-24	Anti arrhytmic composition and methods of treatment
BG104058A (en)	2000-10-31	Diabetes treatment with thiazolydindion and sulphonylurea
EP1023901A4 (en)	2004-10-27	MEDICINES FOR HEPATITIS C AND THE USE THEREOF
AP9901720A0 (en)	1999-12-31	Treatment of diabetes with thiazolidinedione and alpha-glucosidase inhibitors.
YU28700A (sh)	2003-10-31	Upotreba potencijatora osetljivosti na insulin u proizvodnji leka za lečenje hiperglikemije
BG104062A (en)	2000-11-30	Treatment of diabetes with thiazolidindion, stimulant of insulin secretion and alpha-glucosidase inhibitor
BG101884A (en)	1998-10-30	Salts of the clavulanic acid
MY138246A (en)	2009-05-29	Treatment of diabetes with thiazolidione and sulphonylurea.
CA2234936A1 (en)	1999-10-17	Composition for and treatment of inflammatory bowel disease by colon administration of n-acetylglucosamine
NZ503862A (en)	2003-01-31	Use of insulin sensitisers (especially thiazolidinediones) for the treatment of hyperglycaemia
EP1347754A4 (en)	2004-10-13	COMPOSITIONS FOR PREVENTION OF ADHESION
MY118982A (en)	2005-02-28	Method of reducing tissue damage associated with ischemia
WO1999033454A3 (en)	1999-10-21	S-procyclidine for treating urinary incontinence