YU32402A - Konjugati gama interferona - Google Patents

Konjugati gama interferona

Info

Publication number
YU32402A
YU32402A YU32402A YUP32402A YU32402A YU 32402 A YU32402 A YU 32402A YU 32402 A YU32402 A YU 32402A YU P32402 A YUP32402 A YU P32402A YU 32402 A YU32402 A YU 32402A
Authority
YU
Yugoslavia
Prior art keywords
polypeptide
interferon gamma
amino acid
conjugate
conjugates
Prior art date
Application number
YU32402A
Other languages
English (en)
Inventor
Anne Dam Jensen
Kim Vilbour Andersen
Christian Karsten Hansen
Original Assignee
Maxygen Holdings Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maxygen Holdings Ltd. filed Critical Maxygen Holdings Ltd.
Publication of YU32402A publication Critical patent/YU32402A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Konjugat koji ispoljava aktivnost gama interferona i koji uključuje najmanje jedan prvi ne-polipeptidni deo kovalentno vezan za IFG polipeptid, polipeptid koji uključuje amino kiselinsku sekvencu, koja se razlikuje od one kod IFNG polipeptida roditelja po najmanje jednom uvedenom i/ili uklonjenom amino kiselinskom ostatku koji obuhvata vezujuću grupu za ne-polipeptidni deo. Konjugat se može koristiti za lečenje raznih bolesti.[A conjugate exhibiting interferon gamma activity and comprising at least one first non-polypeptide moiety covalently linked to an IFG polypeptide, the polypeptide comprising an amino acid sequence that differs from that of a parent IFNG polypeptide in at least one introduced and/or at least one removed amino acid residue comprising an attachment group for the non-polypeptide moiety. The conjugate may be used for treatment of various diseases.
YU32402A 1999-11-12 2000-11-13 Konjugati gama interferona YU32402A (sh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199901631 1999-11-12
US16629399P 1999-11-18 1999-11-18
DKPA200000447 2000-03-17

Publications (1)

Publication Number Publication Date
YU32402A true YU32402A (sh) 2005-03-15

Family

ID=34195933

Family Applications (1)

Application Number Title Priority Date Filing Date
YU32402A YU32402A (sh) 1999-11-12 2000-11-13 Konjugati gama interferona

Country Status (3)

Country Link
US (1) US7230081B1 (sh)
CN (1) CN1309423C (sh)
YU (1) YU32402A (sh)

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US7982010B2 (en) * 2006-03-31 2011-07-19 Baxter International Inc. Factor VIII polymer conjugates
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PT2101821E (pt) 2006-12-15 2014-10-03 Baxter Int Fator conjugado viia-ácido (poli)siálico com prolongamento do tempo de meia vida in vivo
US8809501B2 (en) 2009-07-27 2014-08-19 Baxter International Inc. Nucleophilic catalysts for oxime linkage
US8642737B2 (en) 2010-07-26 2014-02-04 Baxter International Inc. Nucleophilic catalysts for oxime linkage
ES2597954T3 (es) * 2009-07-27 2017-01-24 Baxalta GmbH Conjugados de proteína de la coagulación sanguínea
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EP3093029A1 (en) 2009-07-27 2016-11-16 Baxalta GmbH Blood coagulation protein conjugates
BR112013015898A2 (pt) 2010-12-22 2018-06-26 Baxter International Inc. derivado de ácido graxo solúvel em água, e, métodos para preparar um derivado de ácido graxo e uma proteína terapêutica conjugada.

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Also Published As

Publication number Publication date
CN1433324A (zh) 2003-07-30
US7230081B1 (en) 2007-06-12
CN1309423C (zh) 2007-04-11

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