YU39480B - Process for obtaining 4,5,6,7-tetrahydrotheno(2,3-c)pyridine derivatives - Google Patents

Process for obtaining 4,5,6,7-tetrahydrotheno(2,3-c)pyridine derivatives

Info

Publication number
YU39480B
YU39480B YU1462/76A YU146276A YU39480B YU 39480 B YU39480 B YU 39480B YU 1462/76 A YU1462/76 A YU 1462/76A YU 146276 A YU146276 A YU 146276A YU 39480 B YU39480 B YU 39480B
Authority
YU
Yugoslavia
Prior art keywords
tetrahydrotheno
obtaining
pyridine derivatives
pyridine
derivatives
Prior art date
Application number
YU1462/76A
Other languages
English (en)
Other versions
YU146276A (en
Inventor
J P Mafrand
Original Assignee
Parcor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parcor filed Critical Parcor
Publication of YU146276A publication Critical patent/YU146276A/xx
Publication of YU39480B publication Critical patent/YU39480B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
YU1462/76A 1975-06-27 1976-06-15 Process for obtaining 4,5,6,7-tetrahydrotheno(2,3-c)pyridine derivatives YU39480B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7520241A FR2315274A1 (fr) 1975-06-27 1975-06-27 Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications

Publications (2)

Publication Number Publication Date
YU146276A YU146276A (en) 1982-05-31
YU39480B true YU39480B (en) 1984-12-31

Family

ID=9157178

Family Applications (1)

Application Number Title Priority Date Filing Date
YU1462/76A YU39480B (en) 1975-06-27 1976-06-15 Process for obtaining 4,5,6,7-tetrahydrotheno(2,3-c)pyridine derivatives

Country Status (26)

Country Link
US (1) US4075340A (fr)
JP (1) JPS607633B2 (fr)
AR (1) AR211777A1 (fr)
AT (1) AT347950B (fr)
BE (1) BE843402A (fr)
CA (1) CA1071635A (fr)
CH (1) CH596169A5 (fr)
DD (1) DD125080A5 (fr)
DE (1) DE2628045A1 (fr)
DK (1) DK279976A (fr)
ES (1) ES449191A1 (fr)
FR (1) FR2315274A1 (fr)
GB (1) GB1492239A (fr)
GR (1) GR60042B (fr)
HU (1) HU172697B (fr)
IE (1) IE43915B1 (fr)
IL (1) IL49702A (fr)
LU (1) LU75230A1 (fr)
MX (1) MX3565E (fr)
NL (1) NL183032C (fr)
PL (1) PL105962B1 (fr)
PT (1) PT65271B (fr)
SE (1) SE421698B (fr)
SU (1) SU628820A3 (fr)
YU (1) YU39480B (fr)
ZA (1) ZA763270B (fr)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4127580A (en) * 1975-02-07 1978-11-28 Parcor Process for the preparation of thieno-pyridine derivatives
FR2395271A1 (fr) * 1977-06-21 1979-01-19 Parcor Procede de preparation de thieno (2,3-c) et thieno (3,2-c) pyridines
GB2038625B (en) * 1978-12-29 1983-01-12 Parcor Therapeutic composition having an antithrombotic and antiblood-platelet-aggregating activity
US4749692A (en) * 1977-06-22 1988-06-07 Sanofi, S.A. Therapeutic compositions having anti-thrombotic and anti-blood-platelet-aggregating activity
FR2397417A1 (fr) * 1977-07-12 1979-02-09 Parcor Procede de preparation de derives de la thienopyridine
AT368504B (de) * 1977-10-15 1982-10-25 Boehringer Sohn Ingelheim Verfahren zur herstellung neuer 4-phenyl-thieno- (2,3-c)-piperidine
US4321266A (en) * 1980-10-06 1982-03-23 Sanofi 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-C] pyridine
FR2508453A1 (fr) * 1981-06-30 1982-12-31 Sanofi Sa Procede de preparation de derives des (thienyl-2)- et thienyl-3)-2 ethylamines et produits ainsi obtenus
US4547514A (en) * 1983-12-05 1985-10-15 A. H. Robins Company, Incorporated Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity
DE3736664A1 (de) * 1987-10-29 1989-05-11 Boehringer Ingelheim Kg Tetrahydro-furo- und -thieno(2,3-c)pyridine, ihre verwendung als arzneimittel und verfahren zu ihrer herstellung
US5294621A (en) * 1992-10-07 1994-03-15 Ortho Pharmaceutical Corporation Thieno tetrahydropyridines useful as class III antiarrhythmic agents
WO2000000472A1 (fr) * 1998-06-30 2000-01-06 Du Pont Pharmaceuticals Company Antagonistes du recepteur 5-ht¿7?
US6090797A (en) * 1998-09-02 2000-07-18 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno(2,3-C)pyridine derivatives
WO2000014090A1 (fr) * 1998-09-02 2000-03-16 Novo Nordisk A/S Derives de 4,5,6,7-tetrahydro-thieno[2,3-c]pyridine
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
AU2003217747A1 (en) * 2002-02-26 2003-09-09 North Shore-Long Island Jewish Research Insitute Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors
EP1734941A2 (fr) 2004-03-25 2006-12-27 The Feinstein Institute for Medical Research Garrot neural
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
WO2006073484A2 (fr) 2004-12-27 2006-07-13 North Shore-Long Island Jewish Research Institute Traitement de troubles inflammatoires par la stimulation electrique du nerf vague
US8391970B2 (en) 2007-08-27 2013-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
WO2009146030A1 (fr) 2008-03-31 2009-12-03 The Feinstein Institute For Medical Research Méthodes et systèmes de réduction d’une inflammation par neuromodulation de l’activité des lymphocytes t
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
CN102215909B (zh) 2008-11-18 2014-09-10 赛博恩特医疗器械公司 优化用于消炎刺激的电极放置的装置和方法
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8788034B2 (en) 2011-05-09 2014-07-22 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
EP2440284B1 (fr) 2009-06-09 2018-09-12 Setpoint Medical Corporation Manchon pour nerf muni d'une poche pour stimulateur sans fil
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
US11051744B2 (en) 2009-11-17 2021-07-06 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
EP2515996B1 (fr) 2009-12-23 2019-09-18 Setpoint Medical Corporation Dispositifs de stimulation neurale et systèmes pour le traitement d'une inflammation chronique
US12172017B2 (en) 2011-05-09 2024-12-24 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
AU2013235487B2 (en) 2012-03-23 2017-09-07 Memorial Sloan-Kettering Cancer Center Treatment of pancreatic and related cancers with 5-acyl-6,7-dihydrothieno[3,2-c]pyridines
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
EP3180327B1 (fr) * 2014-07-28 2019-05-08 Merck Sharp & Dohme Corp. Inhibiteurs du facteur xia
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
US11406833B2 (en) 2015-02-03 2022-08-09 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
EP3405255B1 (fr) 2016-01-20 2025-12-31 Setpoint Medical Corporation Microstimulateurs implantables et systèmes de recharge par induction
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
CN108882885A (zh) 2016-01-20 2018-11-23 赛博恩特医疗器械公司 迷走神经刺激的控制
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
EP3668402B1 (fr) 2017-08-14 2024-07-31 Setpoint Medical Corporation Test de dépistage pour stimulation du nerf vague
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
US12343535B2 (en) 2019-04-12 2025-07-01 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
EP4090424A4 (fr) 2020-01-13 2024-02-21 The Feinstein Institutes for Medical Research Traitement du saignement et de troubles de saignement par stimulation ultrasonore focalisée à haute intensité de la rate
US11938324B2 (en) 2020-05-21 2024-03-26 The Feinstein Institutes For Medical Research Systems and methods for vagus nerve stimulation
WO2022245878A1 (fr) 2021-05-17 2022-11-24 Setpoint Medical Corporation Système d'authentification et d'expiration de paramètre de neurostimulation pour neurostimulation
EP4466064A4 (fr) 2022-01-20 2026-01-14 Setpoint Medical Corp Traitement de troubles inflammatoires

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2215948B1 (fr) * 1973-02-01 1976-05-14 Centre Etd Ind Pharma

Also Published As

Publication number Publication date
JPS525793A (en) 1977-01-17
IE43915B1 (en) 1981-07-01
HU172697B (hu) 1978-11-28
DD125080A5 (fr) 1977-03-30
PT65271A (fr) 1976-07-01
MX3565E (es) 1981-03-13
NL7606574A (nl) 1976-12-29
CA1071635A (fr) 1980-02-12
GR60042B (en) 1978-04-01
SE421698B (sv) 1982-01-25
NL183032C (nl) 1988-07-01
AU1537576A (en) 1978-01-05
ES449191A1 (es) 1977-12-01
NL183032B (nl) 1988-02-01
IE43915L (en) 1976-12-27
ATA461776A (de) 1978-06-15
LU75230A1 (fr) 1977-02-18
ZA763270B (en) 1977-05-25
AR211777A1 (es) 1978-03-15
PL105962B1 (pl) 1979-11-30
BE843402A (fr) 1976-12-27
CH596169A5 (fr) 1978-02-28
FR2315274B1 (fr) 1979-08-10
GB1492239A (en) 1977-11-16
DE2628045A1 (de) 1977-01-20
US4075340A (en) 1978-02-21
FR2315274A1 (fr) 1977-01-21
AT347950B (de) 1979-01-25
PT65271B (fr) 1977-12-10
DK279976A (da) 1976-12-28
SE7607201L (sv) 1976-12-28
SU628820A3 (ru) 1978-10-15
YU146276A (en) 1982-05-31
JPS607633B2 (ja) 1985-02-26
IL49702A0 (en) 1976-08-31
IL49702A (en) 1979-01-31

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