YU43499A - Kristalna hidratovana natrijumova so (e)-4,6-dihloro-3- (2-okso-1-fenilpirolidin-3-iliden metil)-1h-indol-2- karboksilne kiseline - Google Patents

Kristalna hidratovana natrijumova so (e)-4,6-dihloro-3- (2-okso-1-fenilpirolidin-3-iliden metil)-1h-indol-2- karboksilne kiseline

Info

Publication number: YU43499A
Authority: YU; Yugoslavia
Prior art keywords: sodium salt; phenylpyrrolidin; indole; dichloro; oxo
Prior art date: 1997-03-05

Application number

YU43499A

Other languages

English (en)

Serbo-Croatian (sh)

Inventor

Zadeo Cimarosti

Paolo Maragni

Original Assignee

Glaxo Wellcome S.P.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-05

Filing date

1998-03-03

Publication date

2000-12-28

1998-03-03 Application filed by Glaxo Wellcome S.P.A. filed Critical Glaxo Wellcome S.P.A.

2000-12-28 Publication of YU43499A publication Critical patent/YU43499A/sh

Links

159000000000 sodium salts Chemical class 0.000 title abstract 2
VDIRQCDDCGAGET-DHZHZOJOSA-N 4,6-dichloro-3-[(e)-(2-oxo-1-phenylpyrrolidin-3-ylidene)methyl]-1h-indole-2-carboxylic acid Chemical compound OC(=O)C=1NC2=CC(Cl)=CC(Cl)=C2C=1\C=C(C1=O)/CCN1C1=CC=CC=C1 VDIRQCDDCGAGET-DHZHZOJOSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrrole Compounds (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

YU43499A 1997-03-05 1998-03-03 Kristalna hidratovana natrijumova so (e)-4,6-dihloro-3- (2-okso-1-fenilpirolidin-3-iliden metil)-1h-indol-2- karboksilne kiseline YU43499A (sh)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9704498.6A GB9704498D0 (en)	1997-03-05	1997-03-05	Chemical compound

Publications (1)

Publication Number	Publication Date
YU43499A true YU43499A (sh)	2000-12-28

Family

ID=10808697

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU43499A YU43499A (sh)	1997-03-05	1998-03-03	Kristalna hidratovana natrijumova so (e)-4,6-dihloro-3- (2-okso-1-fenilpirolidin-3-iliden metil)-1h-indol-2- karboksilne kiseline

Country Status (29)

Country	Link
EP (1)	EP0966463A1 (is)
JP (1)	JP2001513796A (is)
KR (1)	KR20000075907A (is)
CN (1)	CN1249750A (is)
AP (1)	AP9901637A0 (is)
AR (1)	AR011178A1 (is)
AU (1)	AU6825198A (is)
BG (1)	BG103779A (is)
BR (1)	BR9808305A (is)
CA (1)	CA2282851A1 (is)
CO (1)	CO4940415A1 (is)
EA (1)	EA199900710A1 (is)
EE (1)	EE9900387A (is)
GB (1)	GB9704498D0 (is)
HR (1)	HRP980114A2 (is)
HU (1)	HUP0002109A2 (is)
ID (1)	ID24207A (is)
IL (1)	IL131489A0 (is)
IS (1)	IS5166A (is)
NO (1)	NO994303L (is)
NZ (1)	NZ337315A (is)
OA (1)	OA11154A (is)
PE (1)	PE51399A1 (is)
PL (1)	PL335652A1 (is)
SK (1)	SK119699A3 (is)
TR (1)	TR199902117T2 (is)
WO (1)	WO1998039327A1 (is)
YU (1)	YU43499A (is)
ZA (1)	ZA981791B (is)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9704499D0 (en) *	1997-03-05	1997-04-23	Glaxo Wellcome Spa	Method of manufacture
GB9825988D0 (en) *	1998-11-27	1999-01-20	Pfizer Ltd	Indole derivatives
GB9915231D0 (en)	1999-06-29	1999-09-01	Pfizer Ltd	Pharmaceutical complex
US9737531B2 (en)	2012-07-12	2017-08-22	Glytech, Llc	Composition and method for treatment of depression and psychosis in humans
CN110996948A (zh)	2017-06-12	2020-04-10	格莱泰施有限责任公司	用nmda拮抗剂和d2/5ht2a或选择性5ht2a拮抗剂治疗抑郁症

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9321221D0 (en) *	1993-10-14	1993-12-01	Glaxo Spa	Heterocyclic compounds

1997
- 1997-03-05 GB GBGB9704498.6A patent/GB9704498D0/en active Pending
1998
- 1998-03-03 KR KR1019997007987A patent/KR20000075907A/ko not_active Withdrawn
- 1998-03-03 WO PCT/EP1998/001146 patent/WO1998039327A1/en not_active Ceased
- 1998-03-03 EE EEP199900387A patent/EE9900387A/xx unknown
- 1998-03-03 EP EP98913613A patent/EP0966463A1/en not_active Withdrawn
- 1998-03-03 AU AU68251/98A patent/AU6825198A/en not_active Abandoned
- 1998-03-03 NZ NZ337315A patent/NZ337315A/en unknown
- 1998-03-03 SK SK1196-99A patent/SK119699A3/sk unknown
- 1998-03-03 TR TR1999/02117T patent/TR199902117T2/xx unknown
- 1998-03-03 JP JP53813598A patent/JP2001513796A/ja active Pending
- 1998-03-03 PE PE1998000149A patent/PE51399A1/es not_active Application Discontinuation
- 1998-03-03 CA CA002282851A patent/CA2282851A1/en not_active Abandoned
- 1998-03-03 HU HU0002109A patent/HUP0002109A2/hu unknown
- 1998-03-03 CN CN98803053A patent/CN1249750A/zh active Pending
- 1998-03-03 ZA ZA9801791A patent/ZA981791B/xx unknown
- 1998-03-03 PL PL98335652A patent/PL335652A1/xx unknown
- 1998-03-03 IL IL13148998A patent/IL131489A0/xx unknown
- 1998-03-03 AP APAP/P/1999/001637A patent/AP9901637A0/en unknown
- 1998-03-03 EA EA199900710A patent/EA199900710A1/ru unknown
- 1998-03-03 YU YU43499A patent/YU43499A/sh unknown
- 1998-03-03 AR ARP980100948A patent/AR011178A1/es unknown
- 1998-03-03 BR BR9808305-8A patent/BR9808305A/pt not_active Application Discontinuation
- 1998-03-03 CO CO98011404A patent/CO4940415A1/es unknown
- 1998-03-03 ID IDW990976A patent/ID24207A/id unknown
- 1998-03-04 HR HR9704498.6A patent/HRP980114A2/hr not_active Application Discontinuation
1999
- 1999-08-27 IS IS5166A patent/IS5166A/is unknown
- 1999-09-02 OA OA9900201A patent/OA11154A/fr unknown
- 1999-09-03 NO NO994303A patent/NO994303L/no not_active Application Discontinuation
- 1999-10-04 BG BG103779A patent/BG103779A/xx unknown

Also Published As

Publication number	Publication date
GB9704498D0 (en)	1997-04-23
WO1998039327A1 (en)	1998-09-11
BR9808305A (pt)	2000-05-16
EP0966463A1 (en)	1999-12-29
ID24207A (id)	2000-07-13
EE9900387A (et)	2000-04-17
CO4940415A1 (es)	2000-07-24
PE51399A1 (es)	1999-06-07
IS5166A (is)	1999-08-27
IL131489A0 (en)	2001-01-28
AU6825198A (en)	1998-09-22
SK119699A3 (en)	2000-05-16
KR20000075907A (ko)	2000-12-26
ZA981791B (en)	1999-09-03
TR199902117T2 (xx)	2000-03-21
HRP980114A2 (en)	1998-12-31
NO994303L (no)	1999-11-03
PL335652A1 (en)	2000-05-08
JP2001513796A (ja)	2001-09-04
OA11154A (en)	2003-04-16
CN1249750A (zh)	2000-04-05
NO994303D0 (no)	1999-09-03
AP9901637A0 (en)	1999-09-30
NZ337315A (en)	2001-02-23
EA199900710A1 (ru)	2000-04-24
AR011178A1 (es)	2000-08-02
BG103779A (en)	2000-06-30
CA2282851A1 (en)	1998-09-11
HUP0002109A2 (hu)	2001-04-28

Publication	Publication Date	Title
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ATE179976T1 (de)	1999-05-15	Neue 5-pyrrolyl-2-pyridylmethylsulfinyl benzimidazol-derivate
EE9900217A (et)	1999-12-15	Sulfiinhappe derivaadid, nende valmistamine ja kasutamine
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YU35697A (en)	1999-11-22	Substituted 6,6-hetero-bicyclic derivatives
ATE306261T1 (de)	2005-10-15	Antithrombosemittel
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AU4831899A (en)	2000-01-17	5-HT1F agonists
GB9514518D0 (en)	1995-09-13	Guanidine salt inhibitors of NO synthase and cyclooxygenase
MY123908A (en)	2006-06-30	Meta-azacyclic amino benzoic acid compounds and derivatives thereof
AU2135695A (en)	1995-10-23	Pyrimidine or triazine carboxylic acid derivatives to be used as medicaments
TR199700206A2 (xx)	1997-10-21	Floralkil- ve floralkoksi ikame edilmi� heterosiklik bradikinin-antagonistleri, bunlar�n imal edilmesine mahsus usul ve bunlar�n kullan�lmalar�.
TR200001909T2 (tr)	2000-12-21	Matris metaloprotez inhibitörleri.
DK0758312T3 (da)	2000-05-01	Substituerede fusionerede og broforbundne bicykliske forbindelser som terapeutiske midler
TR199902117T2 (xx)	2000-03-21	(E)-4,6- Dikloro-3-(2-okso-1-fenilpirolidin-3-iliden metil)-1H-�ndol-2-karboksilik asidin kristalimsi hidratlanm�� sodyum tuzu.
ATE248163T1 (de)	2003-09-15	Neuartige, pharmazeutisch aktive verbindung
AU562643B2 (en)	1987-06-18	N-arylpiperazine derivatives
PT1104419E (pt)	2002-09-30	Derivados de azabicicloheptano substituidos no azoto sua preparacao e utilizacao
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ATE268768T1 (de)	2004-06-15	Antithrombosemittel