YU49499A - Postupak za dobijanje halogenida o-(3-amino-2-hidroksi- propil)-hidroksimske kiseline - Google Patents

Postupak za dobijanje halogenida o-(3-amino-2-hidroksi- propil)-hidroksimske kiseline

Info

Publication number: YU49499A
Authority: YU; Yugoslavia
Prior art keywords: formula; hydroxy; amino; carboxamide oxime; propyl
Prior art date: 1997-04-03

Application number

YU49499A

Other languages

English (en)

Serbo-Croatian (sh)

Inventor

Laszlo Urogdi

Mihaly Barabas

Dzede Marvanyos

Magdolna Torok

Zita Csakai

Original Assignee

Biorex Kutato Es Fejleszto Rt.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-03

Filing date

1997-12-15

Publication date

2001-09-28

1997-12-15 Application filed by Biorex Kutato Es Fejleszto Rt. filed Critical Biorex Kutato Es Fejleszto Rt.

2001-09-28 Publication of YU49499A publication Critical patent/YU49499A/sh

Links

239000002253 acid Substances 0.000 title abstract 3
150000004820 halides Chemical class 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title abstract 2
-1 carboxamide oxime Chemical class 0.000 abstract 4
238000000034 method Methods 0.000 abstract 2
LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 abstract 2
HXKKHQJGJAFBHI-UHFFFAOYSA-N 1-aminopropan-2-ol Chemical class CC(O)CN HXKKHQJGJAFBHI-UHFFFAOYSA-N 0.000 abstract 1
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
230000001476 alcoholic effect Effects 0.000 abstract 1
229910001854 alkali hydroxide Inorganic materials 0.000 abstract 1
150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
150000001450 anions Chemical class 0.000 abstract 1
GMWFCJXSQQHBPI-UHFFFAOYSA-N azetidin-3-ol Chemical class OC1CNC1 GMWFCJXSQQHBPI-UHFFFAOYSA-N 0.000 abstract 1
239000002585 base Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000012954 diazonium Substances 0.000 abstract 1
150000001989 diazonium salts Chemical class 0.000 abstract 1
239000012433 hydrogen halide Substances 0.000 abstract 1
229910000039 hydrogen halide Inorganic materials 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
235000010288 sodium nitrite Nutrition 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
- C07C249/12—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reactions not involving the formation of oxyimino groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/02—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by halogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Emergency Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

YU49499A 1997-04-03 1997-12-15 Postupak za dobijanje halogenida o-(3-amino-2-hidroksi- propil)-hidroksimske kiseline YU49499A (sh)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU9700699A HU220971B1 (hu)	1997-04-03	1997-04-03	Eljárás 0-(3-amino-2-hidroxi-propil)-hidroximsav-halogenidek előállítására

Publications (1)

Publication Number	Publication Date
YU49499A true YU49499A (sh)	2001-09-28

Family

ID=89994956

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU49499A YU49499A (sh)	1997-04-03	1997-12-15	Postupak za dobijanje halogenida o-(3-amino-2-hidroksi- propil)-hidroksimske kiseline

Country Status (33)

Country	Link
US (1)	US6180787B1 (fr)
EP (1)	EP0975585A1 (fr)
JP (1)	JP2001521498A (fr)
KR (1)	KR20010005943A (fr)
CN (1)	CN1251574A (fr)
AP (1)	AP9901646A0 (fr)
AR (1)	AR012308A1 (fr)
AU (1)	AU737994B2 (fr)
BG (1)	BG63116B1 (fr)
BR (1)	BR9714717A (fr)
CA (1)	CA2285360A1 (fr)
CO (1)	CO4940491A1 (fr)
EA (1)	EA199900899A1 (fr)
EE (1)	EE03868B1 (fr)
EG (1)	EG22104A (fr)
HR (1)	HRP980175A2 (fr)
HU (1)	HU220971B1 (fr)
ID (1)	ID20016A (fr)
IL (1)	IL132048A0 (fr)
IS (1)	IS5174A (fr)
MA (1)	MA26143A1 (fr)
NO (1)	NO312027B1 (fr)
NZ (1)	NZ500020A (fr)
PE (1)	PE83299A1 (fr)
PL (1)	PL336072A1 (fr)
SK (1)	SK134899A3 (fr)
TN (1)	TNSN98046A1 (fr)
TR (1)	TR199902207T2 (fr)
TW (1)	TW455573B (fr)
UY (1)	UY24945A1 (fr)
WO (1)	WO1998043948A1 (fr)
YU (1)	YU49499A (fr)
ZA (1)	ZA982755B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUP9900475D0 (en) *	1999-02-26	1999-04-28	Biorex Kutato Fejlesztoe Kft	O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component
WO2003057664A1 (fr)	2002-01-11	2003-07-17	Biorex Kutató És Fejlesztö Rt.	Derives de carboxamidine et leur utilisation pour traiter des troubles vasculaires
HUP0303584A3 (en)	2003-10-30	2009-12-28	Cytrx Corp	Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases
WO2013092778A2 (fr) *	2011-12-23	2013-06-27	Akzo Nobel Chemicals International B.V.	Composés chimiques
EP2861413B1 (fr) *	2012-06-14	2019-05-01	Novartis AG	Copolymères contenant de l'azétidinium et leurs utilisations
CN103804309B (zh) *	2012-11-09	2019-08-02	广州喜鹊医药有限公司	一种氯肟类化合物及其制备方法和在制药中的应用
EP4247792A1 (fr)	2020-11-19	2023-09-27	Zevra Denmark A/S	Procédés de préparation de citrate d'arimoclomol et intermédiaires associés

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU207305B (en) *	1988-03-23	1993-03-29	Chinoin Gyogyszer Es Vegyeszet	Improved process for producing amidoxime derivatives
HU207988B (en) *	1988-10-20	1993-07-28	Biorex Kutato Fejlesztoe Kft	Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components
HUT54347A (en) *	1989-01-10	1991-02-28	Chinoin Gyogyszer Es Vegyeszet	Improved process for producing amidoximes

1997
- 1997-04-03 HU HU9700699A patent/HU220971B1/hu not_active IP Right Cessation
- 1997-12-05 KR KR1019997009020A patent/KR20010005943A/ko not_active Withdrawn
- 1997-12-05 NZ NZ500020A patent/NZ500020A/en unknown
- 1997-12-05 JP JP54132298A patent/JP2001521498A/ja active Pending
- 1997-12-05 BR BR9714717-6A patent/BR9714717A/pt not_active Application Discontinuation
- 1997-12-05 AP APAP/P/1999/001646A patent/AP9901646A0/en unknown
- 1997-12-05 SK SK1348-99A patent/SK134899A3/sk unknown
- 1997-12-05 EA EA199900899A patent/EA199900899A1/ru unknown
- 1997-12-05 EP EP97947819A patent/EP0975585A1/fr not_active Withdrawn
- 1997-12-05 AU AU54055/98A patent/AU737994B2/en not_active Ceased
- 1997-12-05 EE EEP199900438A patent/EE03868B1/xx not_active IP Right Cessation
- 1997-12-05 CA CA002285360A patent/CA2285360A1/fr not_active Abandoned
- 1997-12-05 TR TR1999/02207T patent/TR199902207T2/xx unknown
- 1997-12-05 US US09/402,267 patent/US6180787B1/en not_active Expired - Fee Related
- 1997-12-05 CN CN97182087A patent/CN1251574A/zh active Pending
- 1997-12-05 PL PL97336072A patent/PL336072A1/xx unknown
- 1997-12-05 WO PCT/HU1997/000082 patent/WO1998043948A1/fr not_active Ceased
- 1997-12-15 YU YU49499A patent/YU49499A/sh unknown
1998
- 1998-03-30 MA MA25016A patent/MA26143A1/fr unknown
- 1998-03-31 EG EG36098A patent/EG22104A/xx active
- 1998-04-01 ZA ZA982755A patent/ZA982755B/xx unknown
- 1998-04-02 AR ARP980101495A patent/AR012308A1/es not_active Application Discontinuation
- 1998-04-02 TN TNTNSN98046A patent/TNSN98046A1/fr unknown
- 1998-04-02 PE PE1998000247A patent/PE83299A1/es not_active Application Discontinuation
- 1998-04-02 UY UY24945A patent/UY24945A1/es not_active IP Right Cessation
- 1998-04-03 ID IDP980507A patent/ID20016A/id unknown
- 1998-04-03 CO CO98018891A patent/CO4940491A1/es unknown
- 1998-04-03 HR HRP9700699A patent/HRP980175A2/hr not_active Application Discontinuation
- 1998-04-07 TW TW087105087A patent/TW455573B/zh not_active IP Right Cessation
1999
- 1999-09-10 IS IS5174A patent/IS5174A/is unknown
- 1999-09-23 IL IL13204899A patent/IL132048A0/xx unknown
- 1999-09-23 NO NO19994628A patent/NO312027B1/no not_active IP Right Cessation
- 1999-11-02 BG BG103847A patent/BG63116B1/bg unknown

Also Published As

Publication number	Publication date
AU737994B2 (en)	2001-09-06
CO4940491A1 (es)	2000-07-24
NZ500020A (en)	2001-09-28
EE9900438A (et)	2000-04-17
HUP9700699A2 (hu)	1999-01-28
SK134899A3 (en)	2000-06-12
TW455573B (en)	2001-09-21
IS5174A (is)	1999-09-10
EP0975585A1 (fr)	2000-02-02
TNSN98046A1 (fr)	2005-03-15
BG103847A (en)	2000-07-31
US6180787B1 (en)	2001-01-30
TR199902207T2 (xx)	2000-02-21
HU9700699D0 (en)	1997-05-28
BR9714717A (pt)	2000-06-20
NO994628L (no)	1999-09-23
HUP9700699A3 (en)	1999-04-28
PE83299A1 (es)	1999-09-01
CA2285360A1 (fr)	1998-10-08
IL132048A0 (en)	2001-03-19
WO1998043948A1 (fr)	1998-10-08
HU220971B1 (hu)	2002-07-29
AR012308A1 (es)	2000-10-18
NO994628D0 (no)	1999-09-23
JP2001521498A (ja)	2001-11-06
CN1251574A (zh)	2000-04-26
AP9901646A0 (en)	1999-09-30
EE03868B1 (et)	2002-10-15
MA26143A1 (fr)	2004-07-01
AU5405598A (en)	1998-10-22
EA199900899A1 (ru)	2000-04-24
BG63116B1 (bg)	2001-04-30
NO312027B1 (no)	2002-03-04
ZA982755B (en)	1998-10-01
EG22104A (en)	2002-07-31
KR20010005943A (ko)	2001-01-15
ID20016A (id)	1998-09-10
PL336072A1 (en)	2000-06-05
HRP980175A2 (en)	1999-06-30
UY24945A1 (es)	1998-09-28

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US4226778A (en)	1980-10-07	Process for the manufacture of alkylene carbonates
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