YU95986A - Process for making new derivatives 1,1,2,2-tetramethyl-1,2-bis-(2-fluorine-4-hydroxi-phenyl)-ethan - Google Patents

Process for making new derivatives 1,1,2,2-tetramethyl-1,2-bis-(2-fluorine-4-hydroxi-phenyl)-ethan

Info

Publication number: YU95986A
Authority: YU; Yugoslavia
Prior art keywords: group; hydroxi; ethan; tetramethyl; fluorine
Prior art date: 1985-06-08

Application number

YU00959/86A

Other languages

English (en)

Inventor

H Schoenenberger

R W Hartmaan

M Schneider

W Schwarz

J Engel

Original Assignee

Asta Werke Ag Chem Fab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-06-08

Filing date

1986-06-05

Publication date

1988-02-29

1986-06-05 Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab

1988-02-29 Publication of YU95986A publication Critical patent/YU95986A/xx

Links

206010028980 Neoplasm Diseases 0.000 abstract 1
206010060862 Prostate cancer Diseases 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000004457 alkyl amino carbonyl group Chemical group 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
201000001514 prostate carcinoma Diseases 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
- C07C39/367—Halogenated derivatives polycyclic non-condensed, containing only six-membered aromatic rings as cyclic parts, e.g. halogenated poly-hydroxyphenylalkanes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Compositions Of Macromolecular Compounds (AREA)
Polyesters Or Polycarbonates (AREA)
Hydrogenated Pyridines (AREA)
Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)

YU00959/86A 1985-06-08 1986-06-05 Process for making new derivatives 1,1,2,2-tetramethyl-1,2-bis-(2-fluorine-4-hydroxi-phenyl)-ethan YU95986A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3520622		1985-06-08

Publications (1)

Publication Number	Publication Date
YU95986A true YU95986A (en)	1988-02-29

Family

ID=6272805

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU00959/86A YU95986A (en)	1985-06-08	1986-06-05	Process for making new derivatives 1,1,2,2-tetramethyl-1,2-bis-(2-fluorine-4-hydroxi-phenyl)-ethan

Country Status (19)

Country	Link
US (1)	US4745233A (da)
EP (1)	EP0206021B1 (da)
JP (1)	JPS6242953A (da)
AT (1)	ATE36312T1 (da)
AU (1)	AU5847386A (da)
CA (1)	CA1273953A (da)
DD (1)	DD260490A5 (da)
DE (1)	DE3660489D1 (da)
DK (1)	DK268386A (da)
ES (1)	ES8705357A1 (da)
FI (1)	FI862431L (da)
GR (1)	GR861480B (da)
HU (1)	HUT43552A (da)
IL (1)	IL79055A0 (da)
NO (1)	NO862279L (da)
PT (1)	PT82726B (da)
SU (1)	SU1676459A3 (da)
YU (1)	YU95986A (da)
ZA (1)	ZA864262B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH01155753A (ja) *	1987-12-11	1989-06-19	Nippon Telegr & Teleph Corp <Ntt>	留守番電話機
CA2409647C (en) *	2000-05-26	2012-07-03	Harry Fisch	Methods of treating androgen deficiency in men using selective antiestrogens
US7737185B2 (en)	2001-07-09	2010-06-15	Repros Therapeutics Inc.	Methods and compositions with trans-clomiphene
KR100851648B1 (ko)	2001-07-09	2008-08-13	레프로스 쎄라피우틱스 아이엔씨.	남성의 테스토스테론 결핍치료용 물질
KR20070114187A (ko)	2005-03-22	2007-11-29	레프로스 쎄라피우틱스 아이엔씨.	트랜스-클로미펜의 투약 방법
CA2866905C (en)	2007-10-16	2016-04-19	Repros Therapeutics, Inc.	Selected estrogen receptor modulator (serm) for type 2 diabetes
UA113291C2 (xx)	2011-08-04	2017-01-10		Метаболіти транскломіфену і їх застосування
CN104994877A (zh)	2012-11-02	2015-10-21	利普生物药剂公司	用于癌症治疗的反式-克罗米芬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2021588B (en) *	1978-04-05	1983-03-30	Biorex Laboratories Ltd	Bibenzyl derivatives the preparation thereof and pharmaceutical compositions containing them
DE2927050A1 (de) *	1979-07-04	1981-01-15	Biorex Laboratories Ltd	Bibenzylderivate
US4427697A (en) *	1980-11-18	1984-01-24	Biorex Laboratories Limited	1,2-Diphenylethane derivatives
US4467121A (en) *	1980-12-31	1984-08-21	General Electric Company	Fluorinated diphenols and method for their preparation

1986
- 1986-06-04 EP EP86107568A patent/EP0206021B1/de not_active Expired
- 1986-06-04 DE DE8686107568T patent/DE3660489D1/de not_active Expired
- 1986-06-04 AT AT86107568T patent/ATE36312T1/de not_active IP Right Cessation
- 1986-06-05 YU YU00959/86A patent/YU95986A/xx unknown
- 1986-06-06 DD DD86291079A patent/DD260490A5/de unknown
- 1986-06-06 GR GR861480A patent/GR861480B/el unknown
- 1986-06-06 ZA ZA864262A patent/ZA864262B/xx unknown
- 1986-06-06 JP JP61130455A patent/JPS6242953A/ja active Pending
- 1986-06-06 IL IL79055A patent/IL79055A0/xx unknown
- 1986-06-06 NO NO862279A patent/NO862279L/no unknown
- 1986-06-06 CA CA000511010A patent/CA1273953A/en not_active Expired - Lifetime
- 1986-06-06 ES ES555785A patent/ES8705357A1/es not_active Expired
- 1986-06-06 PT PT82726A patent/PT82726B/pt not_active IP Right Cessation
- 1986-06-06 DK DK268386A patent/DK268386A/da not_active Application Discontinuation
- 1986-06-06 AU AU58473/86A patent/AU5847386A/en not_active Abandoned
- 1986-06-06 FI FI862431A patent/FI862431L/fi not_active IP Right Cessation
- 1986-06-06 HU HU862404A patent/HUT43552A/hu unknown
- 1986-06-09 US US06/871,892 patent/US4745233A/en not_active Expired - Fee Related
1987
- 1987-02-06 SU SU874028942A patent/SU1676459A3/ru active

Also Published As

Publication number	Publication date
NO862279D0 (no)	1986-06-06
NO862279L (no)	1986-12-09
SU1676459A3 (ru)	1991-09-07
EP0206021A1 (de)	1986-12-30
DD260490A5 (de)	1988-09-28
IL79055A0 (en)	1986-09-30
FI862431A0 (fi)	1986-06-06
DE3660489D1 (en)	1988-09-15
ES8705357A1 (es)	1987-05-01
CA1273953A (en)	1990-09-11
PT82726B (pt)	1988-12-15
GR861480B (en)	1986-10-07
DK268386A (da)	1986-12-09
FI862431A7 (fi)	1986-12-09
EP0206021B1 (de)	1988-08-10
ZA864262B (en)	1987-02-25
AU5847386A (en)	1986-12-11
US4745233A (en)	1988-05-17
DK268386D0 (da)	1986-06-06
PT82726A (de)	1986-07-01
JPS6242953A (ja)	1987-02-24
ATE36312T1 (de)	1988-08-15
HUT43552A (en)	1987-11-30
FI862431L (fi)	1986-12-09
ES555785A0 (es)	1987-05-01

Publication	Publication Date	Title
CA1259998C (da)	1989-09-26
ZA80403B (en)	1981-01-28	Antineoplastic compositions
DE3269160D1 (en)	1986-03-27	Theophylline derivatives and process for their preparation
YU95986A (en)	1988-02-29	Process for making new derivatives 1,1,2,2-tetramethyl-1,2-bis-(2-fluorine-4-hydroxi-phenyl)-ethan
ZA858169B (en)	1986-06-25	New adamantanamine derivatives,processes for their preparation and drugs in which they are present
ES8101550A1 (es)	1980-12-16	Un procedimiento para la preparacion de nuevos derivados de 2-pirrolidin-metanol.
GR75418B (da)	1984-07-16
EP0234348A3 (en)	1989-04-26	N-glycosyl amide derivatives, method for their preparation and their use as medicaments
GB2000029A (en)	1979-01-04	Anthraquinones for Cancer Therapy
ES469896A1 (es)	1979-01-01	Procedimiento para la obtencion de derivados de la hidroxi-4tiazolinationa-2
ZA86543B (en)	1986-09-24	2-alkoxycarbonylalkyl-3-oxo-5,6-diaryl-as-triazines having utility as therapeutics
GB2175584A (en)	1986-12-03	Kojic acid derivatives and whitening cosmetics containing same
ES8305732A1 (es)	1983-04-16	Procedimiento para preparar derivados de imidazol.
SE8302084D0 (sv)	1983-04-14	New benzimidazole derivatives
ES439180A1 (es)	1977-06-16	Procedimiento para la preparacion de derivados de piperido- na.
GB1522894A (en)	1978-08-31	Anti-sunburn compositions containing 2-phenyl-indole derivatives
DE3264330D1 (en)	1985-07-25	Process for the preparation of cycloalkenon derivatives
ES477534A2 (es)	1979-10-16	Mejoras introducidas en el objeto de la patente principal n.454.779, por procedimiento para la obtencion de hidroxidihe-terociclos eterados.
DE3062286D1 (en)	1983-04-14	9-chloro-prednisolone derivatives, their preparation and their utilization
ES455710A1 (es)	1978-01-01	Procedimiento de preparacion de derivados de tetrahidro-1,5,10, 10a-tiazol (3,4-b)isoquinoleina.
ES474955A1 (es)	1979-12-01	Un procedimiento para la preparacion de un compuesto polici-clico