ZA200000313B - Neuropeptide Y antagonists. - Google Patents

Neuropeptide Y antagonists.

Info

Publication number: ZA200000313B
Authority: ZA; South Africa
Prior art keywords: neuropeptide; antagonists; disorders; antagonist; chem
Prior art date: 1999-01-27

Application number

ZA200000313A

Other languages

English (en)

Inventor

Marlys Hammond

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-27

Filing date

2000-01-25

Publication date

2001-07-25

2000-01-25 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2001-07-25 Publication of ZA200000313B publication Critical patent/ZA200000313B/xx

Links

101710151321 Melanostatin Proteins 0.000 title 1
102400000064 Neuropeptide Y Human genes 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
URPYMXQQVHTUDU-OFGSCBOVSA-N nucleopeptide y Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=C(O)C=C1 URPYMXQQVHTUDU-OFGSCBOVSA-N 0.000 title 1
208000024172 Cardiovascular disease Diseases 0.000 abstract 1
208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000002660 neuropeptide Y receptor antagonist Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Addiction (AREA)
Gynecology & Obstetrics (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

ZA200000313A 1999-01-27 2000-01-25 Neuropeptide Y antagonists. ZA200000313B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US11739599P	1999-01-27	1999-01-27

Publications (1)

Publication Number	Publication Date
ZA200000313B true ZA200000313B (en)	2001-07-25

Family

ID=22372692

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200000313A ZA200000313B (en)	1999-01-27	2000-01-25	Neuropeptide Y antagonists.

Country Status (17)

Country	Link
US (1)	US6197822B1 (fr)
EP (1)	EP1027891B1 (fr)
JP (1)	JP3502586B2 (fr)
KR (1)	KR100372989B1 (fr)
AT (1)	ATE285759T1 (fr)
AU (1)	AU1352000A (fr)
CA (1)	CA2296970C (fr)
CO (1)	CO5170482A1 (fr)
DE (1)	DE69922918T2 (fr)
DK (1)	DK1027891T3 (fr)
ES (1)	ES2234218T3 (fr)
HU (1)	HUP0000307A2 (fr)
IL (1)	IL134157A0 (fr)
NZ (1)	NZ502518A (fr)
PE (1)	PE20001416A1 (fr)
PT (1)	PT1027891E (fr)
ZA (1)	ZA200000313B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6407120B1 (en) *	1999-02-18	2002-06-18	Pfizer Inc.	Neuropeptide Y antagonists
US8129359B2 (en)	2004-06-04	2012-03-06	Ethicon, Inc.	Composition and method for treating post-surgical pain
US8377906B2 (en)	2004-06-04	2013-02-19	Ethicon, Inc.	Compositions and methods for preventing or reducing postoperative ileus and gastric stasis
US20070141156A1 (en) *	2005-12-21	2007-06-21	Uri Herzberg	Compositions and methods for preventing or reducing postoperative ileus and gastric stasis
US8883960B2 (en)	2007-01-04	2014-11-11	Sk Chemicals Co., Ltd.	Polyarylene sulfide resin with excellent luminosity and preparation method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6562862B1 (en) *	1994-10-20	2003-05-13	Eli Lilly And Company	Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
WO1996014307A1 (fr) *	1994-11-07	1996-05-17	Pfizer Inc.	Certains derives de benzylamine a substitutions; une nouvelle classe de ligands specifiques du neuropeptide y1
EP0759441A3 (fr) *	1995-06-30	1999-06-30	Eli Lilly And Company	Procédés de traitement des pathologies associées aux peptides neuropeptide Y
US6048900A (en) *	1998-02-13	2000-04-11	Bayer Corporation	Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
EP1033366A3 (fr) *	1999-02-18	2000-12-27	Pfizer Products Inc.	Dérivés d'amide comme antagonistes de récepteur de Neuropeptide Y (NPY)

1999
- 1999-12-23 DK DK99310483T patent/DK1027891T3/da active
- 1999-12-23 EP EP99310483A patent/EP1027891B1/fr not_active Expired - Lifetime
- 1999-12-23 ES ES99310483T patent/ES2234218T3/es not_active Expired - Lifetime
- 1999-12-23 PT PT99310483T patent/PT1027891E/pt unknown
- 1999-12-23 DE DE69922918T patent/DE69922918T2/de not_active Expired - Fee Related
- 1999-12-23 AT AT99310483T patent/ATE285759T1/de not_active IP Right Cessation
- 1999-12-29 CO CO99081405A patent/CO5170482A1/es not_active Application Discontinuation
2000
- 2000-01-20 IL IL13415700A patent/IL134157A0/xx unknown
- 2000-01-24 AU AU13520/00A patent/AU1352000A/en not_active Abandoned
- 2000-01-25 US US09/491,293 patent/US6197822B1/en not_active Expired - Fee Related
- 2000-01-25 CA CA002296970A patent/CA2296970C/fr not_active Expired - Fee Related
- 2000-01-25 ZA ZA200000313A patent/ZA200000313B/xx unknown
- 2000-01-26 HU HU0000307A patent/HUP0000307A2/hu unknown
- 2000-01-26 KR KR10-2000-0003550A patent/KR100372989B1/ko not_active Expired - Fee Related
- 2000-01-26 NZ NZ502518A patent/NZ502518A/en unknown
- 2000-01-26 PE PE2000000055A patent/PE20001416A1/es not_active Application Discontinuation
- 2000-01-27 JP JP2000018938A patent/JP3502586B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR100372989B1 (ko)	2003-02-25
EP1027891A2 (fr)	2000-08-16
EP1027891B1 (fr)	2004-12-29
US6197822B1 (en)	2001-03-06
ATE285759T1 (de)	2005-01-15
DE69922918D1 (de)	2005-02-03
HUP0000307A2 (hu)	2000-12-28
DE69922918T2 (de)	2006-03-30
HU0000307D0 (en)	2000-03-28
DK1027891T3 (da)	2005-05-09
EP1027891A3 (fr)	2002-07-17
CA2296970C (fr)	2004-11-02
KR20000053607A (ko)	2000-08-25
CA2296970A1 (fr)	2000-07-27
PT1027891E (pt)	2005-04-29
IL134157A0 (en)	2001-04-30
AU1352000A (en)	2000-08-03
PE20001416A1 (es)	2000-12-18
JP2000212077A (ja)	2000-08-02
CO5170482A1 (es)	2002-06-27
NZ502518A (en)	2001-06-29
JP3502586B2 (ja)	2004-03-02
ES2234218T3 (es)	2005-06-16

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GB9927056D0 (en)	2000-01-12	Thyroid receptor antagonists for the treatment of cardiac and metabolic disorders
AU4288000A (en)	2000-10-04	Modified amino-acid amides as cgrp antagonists
ZA200108130B (en)	2002-06-06	Treatment of pulmonary hypertension.
ZA200201788B (en)	2003-08-27	Substituted 1,5-dihydropyrrol-2-on derivatives as NMDA receptor antagonists for the treatment of pain.
WO2000027850A3 (fr)	2000-08-03	Antagonistes de recepteurs du crf et methodes associees
IL144741A0 (en)	2002-06-30	1-aryl-1,3,5-triazine-4-thione-2,6-diones, production thereof and use thereof as herbicides
IL134157A0 (en)	2001-04-30	Neuropeptide y antagonists
CA2371554A1 (fr)	2000-11-09	Composition pharmaceutique comportant un antagoniste de l'angiotensine ii pour la prevention, le traitement ou le blocage du developpement de la retinopathie simple et de la retinopathie preproliferative
PT896822E (pt)	2003-07-31	4-aminopirrolo (3,2-d)pirimidinas como antagonistas do receptor de neuropeptideo y
BR0000486A (pt)	2001-08-21	Antagonistas do neuropeptìdeo y
HRP20040691A2 (en)	2004-12-31	2'-halo-3',5'-dialkoxyphen-1'-yl-imino-2-imidazolidine and the use thereof as a drug
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NZ334438A (en)	2000-10-27	(S)-7-[(4,4'-bipiperidrin-1-yl)carbonyl]-2,3,4,5-tetrahydro-4-methyl-3-oxo-1H-1,4-benzodiazepine-2-acetic acid hydrochloride as a platelet aggregation inhibitor
SG84585A1 (en)	2001-11-20	Novel substituted 1,2,4-trioxanes as antimalarial agents and a process of producing the substituted 1,2,4-trioxanes
PL355493A1 (en)	2004-05-04	Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and the use thereof as medicaments
ES1042371Y (es)	2000-01-16	"elevador perfeccionado".
ITBO20020168A0 (it)	2002-03-29	Macchina universale per l'orientamento e l'alimentazione automatica di carciofi
ITAT990002U1 (it)	1999-04-29	Progetto "millenium due"
ZA200307077B (en)	2004-07-01	"A table".
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UA3340S (uk)	1999-12-29	Машина "смита"
IT248736Y1 (it)	2003-02-12	Dispositivo perfezionato per l'ossigeno-ozono terapia.