ZA200005374B - Aerosol composition. - Google Patents

Aerosol composition. Download PDF

Info

Publication number
ZA200005374B
ZA200005374B ZA200005374A ZA200005374A ZA200005374B ZA 200005374 B ZA200005374 B ZA 200005374B ZA 200005374 A ZA200005374 A ZA 200005374A ZA 200005374 A ZA200005374 A ZA 200005374A ZA 200005374 B ZA200005374 B ZA 200005374B
Authority
ZA
South Africa
Prior art keywords
particulate material
composition according
less
propellant
range
Prior art date
Application number
ZA200005374A
Other languages
English (en)
Inventor
Paul Alfred Dickinson
Simon John Warren
Original Assignee
Univ Cardiff
Cardiff Scintigraphics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10829846&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200005374(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Cardiff, Cardiff Scintigraphics Ltd filed Critical Univ Cardiff
Publication of ZA200005374B publication Critical patent/ZA200005374B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ZA200005374A 1998-04-03 2000-10-03 Aerosol composition. ZA200005374B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9807232.5A GB9807232D0 (en) 1998-04-03 1998-04-03 Aerosol composition

Publications (1)

Publication Number Publication Date
ZA200005374B true ZA200005374B (en) 2002-01-03

Family

ID=10829846

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200005374A ZA200005374B (en) 1998-04-03 2000-10-03 Aerosol composition.

Country Status (17)

Country Link
US (2) US6737044B1 (fr)
EP (1) EP1069887B8 (fr)
JP (1) JP2002510614A (fr)
KR (1) KR20010072563A (fr)
CN (1) CN1215832C (fr)
AT (1) ATE474555T1 (fr)
AU (1) AU761518B2 (fr)
BR (1) BR9909394A (fr)
CA (1) CA2327336C (fr)
DE (1) DE69942606D1 (fr)
ES (1) ES2349184T3 (fr)
GB (1) GB9807232D0 (fr)
ID (1) ID27586A (fr)
IL (1) IL138770A0 (fr)
MX (1) MXPA00009660A (fr)
WO (1) WO1999051205A1 (fr)
ZA (1) ZA200005374B (fr)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9807232D0 (en) 1998-04-03 1998-06-03 Univ Cardiff Aerosol composition
DE19921693A1 (de) 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
GB9928311D0 (en) * 1999-11-30 2000-01-26 Novartis Ag Organic compounds
NZ522672A (en) * 2000-05-23 2004-07-30 Glaxo Group Ltd Aerosol container for formulations of salmeterol xinafoate and preparation process thereof
GB0015043D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
US20040081627A1 (en) * 2000-10-09 2004-04-29 Jinks Phillip A Medicinal aerosol formulations
AU2002222304B2 (en) * 2000-12-22 2004-03-18 Glaxo Group Limited Metered dose inhaler for salmeterol xinafoate
EP1359902B1 (fr) * 2001-02-06 2007-08-08 Innovata Biomed Limited Composition bimodale de poudre seche pour l'inhalation
WO2002080859A2 (fr) * 2001-03-20 2002-10-17 Glaxo Group Limited Associations de medicaments administrees par inhalation
WO2003024396A2 (fr) * 2001-09-17 2003-03-27 Glaxo Group Limited Formulations de medicament en poudre seche
US20050147566A1 (en) * 2002-03-12 2005-07-07 Scott Fleming Site specific delivery of co-administered drugs via inhalation
GB0219512D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Inhalation compositions with high drug ratios
US20050158248A1 (en) * 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
AU2003269989B8 (en) * 2002-08-21 2009-11-12 Norton Healthcare Ltd. Inhalation composition
EP1545669B1 (fr) * 2002-09-06 2011-11-09 3M Innovative Properties Company Valve de dosage pour aerosol doseur a debit stable
US7497214B2 (en) * 2002-09-16 2009-03-03 3M Innovative Properties Company Aerosol dispensers and adaptors therefor
GB0221343D0 (en) * 2002-09-16 2002-10-23 3M Innovative Properties Co Aerosol dispensers and adaptors therefor
WO2004073729A1 (fr) 2003-02-21 2004-09-02 Translational Research Ltd. Compositions destinees a l'administration nasale d'un medicament
CA2519287A1 (fr) 2003-03-27 2004-10-14 Bioactis Limited Applicateur de medicament en poudre pour cavite nasale
US20060225733A1 (en) * 2003-06-24 2006-10-12 Cipla Limited Pharmaceutical dispensing aid
SE0303179D0 (sv) * 2003-11-26 2003-11-26 Astrazeneca Ab Novel compounds
WO2005051511A1 (fr) * 2003-11-28 2005-06-09 Mitsubishi Chemical Corporation Methode de production de particules fines d'un compose organique
DE102004011381A1 (de) * 2004-03-05 2005-09-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Impaktionsdüse für treibgasbetriebene Dosieraerosole
CA2567334A1 (fr) * 2004-05-20 2005-12-08 Discovery Laboratories, Inc. Procedes, systemes et dispositifs destines a une administration pulmonaire non invasive
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
US8028697B2 (en) 2005-04-28 2011-10-04 Trudell Medical International Ventilator circuit and method for the use thereof
US20060260606A1 (en) * 2005-05-18 2006-11-23 Coifman Robert E Inhalable formulations of amphotericin B and methods and devices for delivery thereof
US8367734B1 (en) 2005-08-11 2013-02-05 Amphastar Pharmaceuticals Inc. Stable epinephrine suspension formulation with high inhalation delivery efficiency
DE102006014433A1 (de) * 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen
US20080269347A1 (en) * 2006-09-28 2008-10-30 Azopharma, Inc. Epinephrine formulations
CN101668544B (zh) 2006-12-26 2013-04-24 株式会社新日本科学 经鼻投用制剂
US20080202627A1 (en) * 2007-02-23 2008-08-28 Mas Gregory V Dosing System and Method
JP5570996B2 (ja) 2007-12-14 2014-08-13 エアロデザインズ インコーポレイテッド エアロゾル化可能な食料品の送達
EP2100598A1 (fr) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
EP2100599A1 (fr) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
HUE028653T2 (en) 2008-03-17 2016-12-28 Discovery Lab Inc Respiratory circuit adapter and direct aerosol delivery system
US8596265B2 (en) 2008-10-22 2013-12-03 Trudell Medical International Modular aerosol delivery system
CA2754691C (fr) 2009-03-26 2019-07-30 Pulmatrix, Inc. Formulations de poudre seche et methodes pour traiter des maladies pulmonaires
US9101539B2 (en) 2009-05-15 2015-08-11 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
GB2472327B (en) 2009-07-31 2013-03-13 Shin Nippon Biomedical Lab Ltd Intranasal granisetron and nasal applicator
EP2504013A1 (fr) 2009-11-24 2012-10-03 Gilead Sciences, Inc. Fosfomycine/tobramycine inhalées pour le traitement d'une maladie respiratoire obstructive chronique
WO2011081937A1 (fr) 2009-12-15 2011-07-07 Gilead Sciences, Inc. Composés de type corticostéroïde-bêta-agoniste-antagoniste muscarinique pour applications thérapeutiques
ES2702753T3 (es) 2010-01-05 2019-03-05 Microdose Therapeutx Inc Dispositivo de inhalación
US8367829B2 (en) 2010-05-10 2013-02-05 Gilead Sciences, Inc. Bi-functional pyrazolopyridine compounds
EP2569285A1 (fr) 2010-05-10 2013-03-20 Gilead Sciences, Inc. Dérivés quinoliniques bifonctionnels
AU2011296343B2 (en) 2010-08-30 2015-12-10 Pulmatrix Operating Company, Inc. Dry powder formulations and methods for treating pulmonary diseases
EP2464346A1 (fr) 2010-08-30 2012-06-20 Pulmatrix, Inc. Méthodes de traitement de la mucoviscidose
CN102416179B (zh) 2010-09-28 2014-05-07 益得生物科技股份有限公司 用于哮喘的吸入性复方组合物
RU2017144619A (ru) 2010-09-29 2019-02-20 Пулмэтрикс, Инк. Катионы одновалентных металлов сухих порошков для ингаляций
EP3470057B1 (fr) 2010-09-29 2021-11-03 Pulmatrix Operating Company, Inc. Poudres sèches cationiques contenants un sel de magnésium
FR2971772B1 (fr) * 2011-02-17 2013-03-22 Valois Sas Dispositif de distribution de produit fluide.
TWI399202B (zh) 2011-03-17 2013-06-21 Intech Biopharm Ltd 製備用於治療呼吸道疾病之定量噴霧吸入劑的製程方法
FR2973786B1 (fr) * 2011-04-06 2014-07-04 Valois Sas Bague pour dispositif de distribution de produit fluide.
EP2510928A1 (fr) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium pour l'amélioration du sommeil des patients avec des maldadies respiratoires
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
HUE039734T2 (hu) 2012-05-29 2019-01-28 Parion Sciences Inc Nátriumcsatorna-blokkoló aktivitású, dendrimerszerû amino-amid-származékok száraz szem és más nyálkahártya-megbetegedések kezelésére
CA2895512C (fr) 2012-12-17 2021-10-19 Parion Sciences, Inc. Derives de chloro-pyrazine carboxamide utiles dans le traitement de maladies favorisees par une hydratation insuffisante des muqueuses
CN108658876A (zh) 2012-12-17 2018-10-16 帕里昂科学公司 3,5-二氨基-6-氯-n-(n-(4-苯基丁基)甲脒基)吡嗪-2-甲酰胺化合物
ES2674665T3 (es) 2012-12-17 2018-07-03 Parion Sciences, Inc. Compuestos de 3,5-diamino-6-cloro-N-(N-(4-fenilbutilo)carbamimidoilo)-pirazina-2-carboxamida
HK1218720A1 (zh) 2013-04-30 2017-03-10 欧缇托匹克公司 干粉制剂及使用方法
WO2015120389A1 (fr) 2014-02-10 2015-08-13 Patara Pharma, LLC Traitement utilisant des stabilisateurs de mastocytes pour des troubles systémiques
PL3104854T3 (pl) 2014-02-10 2020-11-30 Respivant Sciences Gmbh Stabilizatory komórek tucznych do leczenia choroby płuc
GB201402513D0 (en) 2014-02-13 2014-04-02 Cardiff Scintigraphics Ltd Pressurised metered dose inhalers and method of manufacture
ES2922206T3 (es) 2014-02-20 2022-09-09 Otitopic Inc Formulaciones de polvo seco para la inhalación
ES2942297T3 (es) 2014-07-31 2023-05-31 Vectura Inc Formulaciones de polvo seco para inhalación
US10265296B2 (en) 2015-08-07 2019-04-23 Respivant Sciences Gmbh Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders
WO2017027387A1 (fr) 2015-08-07 2017-02-16 Patara Pharma, LLC Méthodes de traitement de troubles liés aux mastocytes par des stabilisateurs de mastocytes
EP3506893A4 (fr) 2016-08-31 2020-01-22 Respivant Sciences GmbH Compositions de cromolyne pour le traitement de la toux chronique due à une fibrose pulmonaire idiopathique
JP2019531308A (ja) 2016-10-07 2019-10-31 レシュピファント サイエンシス ゲゼルシャフト ミット ベシュレンクター ハフトゥングRespivant Sciences Gmbh 肺線維症の治療のためのクロモリン組成物
CN107529499B (zh) * 2017-04-20 2020-06-09 苏州康乐辉医药科技有限公司 一种气雾剂药液浓度稳定装置
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
CN118695855A (zh) * 2022-01-21 2024-09-24 香港大学 通过单次鼻内施用用于鼻和肺沉积的抗病毒剂的双重靶向粉末制剂

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3046863A1 (de) 1980-12-12 1982-07-22 Robert Bosch Gmbh, 7000 Stuttgart Elektronisch gesteuertes kraftstoffzumesssystem fuer eine brennkraftmaschine
GB8613811D0 (en) * 1986-06-06 1986-07-09 Phares Pharm Res Nv Composition & method
GB8828477D0 (en) 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
JPH05508616A (ja) * 1989-02-23 1993-12-02 ローヌー プーラン ローラー インターナショナル(ホウルディングス)インコーポレイテッド 治療用エアロゾル剤
CH680263A5 (fr) 1989-07-20 1992-07-31 Norman Godin
CA2085884C (fr) 1990-06-29 2001-12-04 Asit Somani Compositions d'aerosol sous pression
JP2769925B2 (ja) 1990-10-18 1998-06-25 ミネソタ マイニング アンド マニュファクチャリング カンパニー ベクロメタゾン17,21ジプロピオネートを含んで成るエアロゾル製剤
GB9024366D0 (en) 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
EP0504112A3 (en) 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
EP0561166A1 (fr) 1992-03-17 1993-09-22 ASTA Medica Aktiengesellschaft Compositions d'aérosol contenant le composé D-18024 et ses analogues
CA2115444C (fr) * 1992-06-12 2000-10-03 Yuji Makino Preparation pour administration intratracheobronchique
DE69413955T2 (de) * 1993-03-17 1999-04-01 Minnesota Mining And Mfg. Co., Saint Paul, Minn. Aerosolzusammensetzung enthaltend einen aus ester-, amid- oder merkaptoester- derivat dispergiermittel
GB9404945D0 (en) * 1994-03-15 1994-04-27 Glaxo Group Ltd Pharmaceutical composition
GB9419269D0 (en) * 1994-09-23 1994-11-09 Unilever Plc Aerosol
GB9426252D0 (en) 1994-12-24 1995-02-22 Glaxo Group Ltd Pharmaceutical composition
RU2101054C1 (ru) 1996-04-30 1998-01-10 Закрытое акционерное общество "Техно-ТМ" Аэрозолеобразующий состав для тушения пожаров и способ его получения
RO121834B1 (ro) * 1998-03-16 2008-06-30 Inhale Therapeutic Systems, Inc. Dispozitiv pentru administrarea unui agent activ
GB9807232D0 (en) 1998-04-03 1998-06-03 Univ Cardiff Aerosol composition
US6136294C1 (en) 1998-09-22 2002-09-24 Aeropharm Technology Inc Amino acid stabilized medical aerosol formulation

Also Published As

Publication number Publication date
AU3162099A (en) 1999-10-25
ATE474555T1 (de) 2010-08-15
US20050249674A1 (en) 2005-11-10
ID27586A (id) 2001-04-12
WO1999051205A1 (fr) 1999-10-14
BR9909394A (pt) 2000-12-05
EP1069887B1 (fr) 2010-07-21
ES2349184T3 (es) 2010-12-28
JP2002510614A (ja) 2002-04-09
CA2327336A1 (fr) 1999-10-14
CA2327336C (fr) 2008-07-08
CN1303270A (zh) 2001-07-11
US6737044B1 (en) 2004-05-18
EP1069887B8 (fr) 2010-08-25
CN1215832C (zh) 2005-08-24
IL138770A0 (en) 2001-10-31
US7481995B2 (en) 2009-01-27
EP1069887A1 (fr) 2001-01-24
GB9807232D0 (en) 1998-06-03
KR20010072563A (ko) 2001-07-31
AU761518B2 (en) 2003-06-05
MXPA00009660A (es) 2003-07-14
DE69942606D1 (de) 2010-09-02

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