ZA200305437B - Stabilized brivudine topical formulations containing metal oxide pigments. - Google Patents

Stabilized brivudine topical formulations containing metal oxide pigments.

Info

Publication number: ZA200305437B
Authority: ZA; South Africa
Prior art keywords: stabilized; metal oxide; containing metal; formulations containing; topical formulations
Prior art date: 2001-01-17

Application number

ZA200305437A

Other languages

English (en)

Inventor

Ulrike Gehlert

Karsten Groeger

Reinhard Schmitz

Karl-Heinz Schrader

Andreas Schrader

Marc Wihsmann

Carlo Alberto Maggi

Stefano Manzini

Bettina Stubinski

Original Assignee

Berlin Chemie Ag

Menarini Ricerche Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-01-17

Filing date

2003-07-15

Publication date

2004-07-15

2003-07-15 Application filed by Berlin Chemie Ag, Menarini Ricerche Spa filed Critical Berlin Chemie Ag

2004-07-15 Publication of ZA200305437B publication Critical patent/ZA200305437B/xx

Links

229960001169 brivudine Drugs 0.000 title 1
ODZBBRURCPAEIQ-PIXDULNESA-N helpin Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(\C=C\Br)=C1 ODZBBRURCPAEIQ-PIXDULNESA-N 0.000 title 1
229910044991 metal oxide Inorganic materials 0.000 title 1
150000004706 metal oxides Chemical class 0.000 title 1
239000000049 pigment Substances 0.000 title 1
239000012049 topical pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Virology (AREA)
Dermatology (AREA)
Inorganic Chemistry (AREA)
Biochemistry (AREA)
Communicable Diseases (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Biotechnology (AREA)
Medicinal Preparation (AREA)
Cosmetics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA200305437A 2001-01-17 2003-07-15 Stabilized brivudine topical formulations containing metal oxide pigments. ZA200305437B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01100968		2001-01-17

Publications (1)

Publication Number	Publication Date
ZA200305437B true ZA200305437B (en)	2004-07-15

Family

ID=8176229

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200305437A ZA200305437B (en)	2001-01-17	2003-07-15	Stabilized brivudine topical formulations containing metal oxide pigments.

Country Status (28)

Country	Link
US (1)	US20040087602A1 (cs)
EP (1)	EP1365772A2 (cs)
JP (1)	JP2004519460A (cs)
KR (1)	KR20030070109A (cs)
CN (1)	CN1236777C (cs)
AR (1)	AR035530A1 (cs)
AU (1)	AU2002244642B2 (cs)
BG (1)	BG107988A (cs)
BR (1)	BR0206478A (cs)
CA (1)	CA2434743A1 (cs)
CZ (1)	CZ20031912A3 (cs)
EE (1)	EE200300322A (cs)
HR (1)	HRP20030559A2 (cs)
HU (1)	HUP0302741A3 (cs)
IL (1)	IL156933A0 (cs)
MA (1)	MA26266A1 (cs)
MX (1)	MXPA03006307A (cs)
MY (1)	MY136633A (cs)
NO (1)	NO20033206L (cs)
PE (1)	PE20020818A1 (cs)
PL (1)	PL365741A1 (cs)
RU (1)	RU2280453C2 (cs)
SK (1)	SK8992003A3 (cs)
TN (1)	TNSN03036A1 (cs)
UA (1)	UA80673C2 (cs)
WO (1)	WO2002056913A2 (cs)
YU (1)	YU57103A (cs)
ZA (1)	ZA200305437B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102005046769A1 (de) *	2005-09-29	2007-04-05	Berlin-Chemie Ag	Lichtstabile, brivudinhaltige pharmazeutische Formulierung zur Behandlung von Augenherpes (Herpes Ophthalmicus)
FR2936706B1 (fr) *	2008-10-08	2010-12-17	Oreal	Composition cosmetique contenant un derive de dibenzoylmethane et un compose dithiolane ; procede de photostabilisation du derive de dibenzoylmethane
KR20110117133A (ko) *	2009-01-29	2011-10-26	다이닛본 스미토모 세이야꾸 가부시끼가이샤	내핵을 갖는 구강 내 붕괴 정
BR112017019920B1 (pt) *	2015-03-19	2023-11-07	Daiichi Sankyo Company, Limited	Preparação sólida farmacêutica, e, método para estabilização de uma preparação sólida farmacêutica
CN104988791A (zh) *	2015-06-25	2015-10-21	广东义晟实业有限公司	一种抗病毒添加剂及添加该添加剂的胶水和uv漆

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0072137A1 (en) *	1981-08-01	1983-02-16	Beecham Group Plc	Antiviral deoxyuridine compounds
HU196038B (en) *	1987-08-07	1988-09-28	Mta Koezponti Kemiai Kutato In	Process for producing antiherpetic pharmaceutics for external use, containing 5-isopropyl-2'-beta-deoxy-uridine
DE4122337A1 (de) *	1991-07-05	1993-01-14	Cedona Pharm Bv	Pharmazeutische zubereitung
FR2737118B1 (fr) *	1995-07-28	1997-09-05	Oreal	Composition dermatologique ou pharmaceutique, procede de preparation et utilisation
GB9521454D0 (en) *	1995-10-19	1995-12-20	Kappa Pharmaceuticals Ltd	Compositions for the treatment of conditions caused by herpes virus
US6558710B1 (en) *	1999-06-14	2003-05-06	Helen Rebecca Godfrey	Topical zinc compositions and methods of use
DE10162593A1 (de) *	2001-12-19	2003-07-03	Menarini Ricerche Spa	Stabilisierte topische Brivudin-Formulierungen

2001
- 2001-12-24 MY MYPI20015863A patent/MY136633A/en unknown
2002
- 2002-01-10 BR BR0206478-2A patent/BR0206478A/pt not_active IP Right Cessation
- 2002-01-10 HU HU0302741A patent/HUP0302741A3/hu unknown
- 2002-01-10 RU RU2003121639/15A patent/RU2280453C2/ru not_active IP Right Cessation
- 2002-01-10 MX MXPA03006307A patent/MXPA03006307A/es not_active Application Discontinuation
- 2002-01-10 CN CNB028037448A patent/CN1236777C/zh not_active Expired - Fee Related
- 2002-01-10 EE EEP200300322A patent/EE200300322A/xx unknown
- 2002-01-10 SK SK899-2003A patent/SK8992003A3/sk not_active Application Discontinuation
- 2002-01-10 IL IL15693302A patent/IL156933A0/xx unknown
- 2002-01-10 HR HR20030559A patent/HRP20030559A2/hr not_active Application Discontinuation
- 2002-01-10 US US10/466,305 patent/US20040087602A1/en not_active Abandoned
- 2002-01-10 CA CA002434743A patent/CA2434743A1/en not_active Abandoned
- 2002-01-10 YU YU57103A patent/YU57103A/sh unknown
- 2002-01-10 AU AU2002244642A patent/AU2002244642B2/en not_active Ceased
- 2002-01-10 EP EP02712810A patent/EP1365772A2/en not_active Withdrawn
- 2002-01-10 JP JP2002557420A patent/JP2004519460A/ja active Pending
- 2002-01-10 KR KR10-2003-7009444A patent/KR20030070109A/ko not_active Ceased
- 2002-01-10 WO PCT/EP2002/000163 patent/WO2002056913A2/en not_active Ceased
- 2002-01-10 CZ CZ20031912A patent/CZ20031912A3/cs unknown
- 2002-01-10 PL PL02365741A patent/PL365741A1/xx not_active Application Discontinuation
- 2002-01-16 AR ARP020100151A patent/AR035530A1/es not_active Application Discontinuation
- 2002-01-16 PE PE2002000027A patent/PE20020818A1/es not_active Application Discontinuation
- 2002-10-01 UA UA2003076388A patent/UA80673C2/uk unknown
2003
- 2003-06-30 MA MA27219A patent/MA26266A1/fr unknown
- 2003-07-08 TN TNPCT/EP2002/000163A patent/TNSN03036A1/fr unknown
- 2003-07-10 BG BG107988A patent/BG107988A/bg unknown
- 2003-07-15 ZA ZA200305437A patent/ZA200305437B/xx unknown
- 2003-07-15 NO NO20033206A patent/NO20033206L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
BG107988A (bg)	2004-09-30
AU2002244642B2 (en)	2005-12-15
KR20030070109A (ko)	2003-08-27
UA80673C2 (en)	2007-10-25
WO2002056913A3 (en)	2002-11-07
EE200300322A (et)	2003-10-15
HRP20030559A2 (en)	2005-06-30
MA26266A1 (fr)	2004-09-01
TNSN03036A1 (en)	2005-04-08
HUP0302741A2 (hu)	2003-11-28
RU2003121639A (ru)	2005-02-10
CA2434743A1 (en)	2002-07-25
BR0206478A (pt)	2003-12-30
RU2280453C2 (ru)	2006-07-27
WO2002056913A2 (en)	2002-07-25
PE20020818A1 (es)	2002-10-21
HUP0302741A3 (en)	2007-06-28
IL156933A0 (en)	2004-02-08
JP2004519460A (ja)	2004-07-02
AR035530A1 (es)	2004-06-02
PL365741A1 (en)	2005-01-10
MXPA03006307A (es)	2003-09-16
CN1486185A (zh)	2004-03-31
NO20033206D0 (no)	2003-07-15
EP1365772A2 (en)	2003-12-03
CZ20031912A3 (cs)	2004-01-14
CN1236777C (zh)	2006-01-18
NO20033206L (no)	2003-07-15
SK8992003A3 (en)	2003-11-04
YU57103A (sh)	2006-08-17
US20040087602A1 (en)	2004-05-06
MY136633A (en)	2008-11-28

Publication	Publication Date	Title
GB0108082D0 (en)	2001-05-23	Topical composition
ZA200205749B (en)	2003-07-25	Stabilized aqueous acidic antiperspirant compositions and related methods.
AU2002336401A1 (en)	2003-03-18	Nitric oxide generation
MXPA03008961A (es)	2004-02-12	Composicion de vacuna.
AU2002354236A1 (en)	2003-07-09	Oxide catalyst composition
MXPA03008275A (es)	2003-12-12	Formulas antibacteriales.
MXPA02001855A (es)	2003-07-14	Composicion mejorada de revestimiento.
AU2002366309A1 (en)	2003-06-30	Metal oxide dispersion
AU2002351854A1 (en)	2003-05-19	Ink formulations and uses thereof
AUPR113700A0 (en)	2000-11-23	Transition metal oxide compositions
IL140949A0 (en)	2002-02-10	Nitric oxide (no) detector
ZA200108248B (en)	2002-12-24	Antiperspirant compositions.
PL369581A1 (en)	2005-05-02	Stabilized brivudine topical formulations
GB0106601D0 (en)	2001-05-09	Antiperspirant formulations
ZA200302929B (en)	2004-04-14	Compositions comprising cyclohexamantane.
MXPA03007693A (es)	2003-12-04	Composicion para la piel.
MXPA03007314A (es)	2003-12-04	Composicion para la piel para reducir aceites y grasa de la piel.
IL161235A0 (en)	2004-09-27	Fsh composition, its preparation and use
GB0116945D0 (en)	2001-09-05	Antiperspirant formulations
GB0116946D0 (en)	2001-09-05	Antiperspirant formulations
EG23378A (en)	2005-02-28	Composition.
ZA200305437B (en)	2004-07-15	Stabilized brivudine topical formulations containing metal oxide pigments.
AU2001267693A1 (en)	2002-02-18	Antiperspirant formulations
AU2001286996A1 (en)	2002-03-13	Stabilized fgf formulations containing reducing agents
MXPA03008077A (es)	2003-12-12	Composicion humedecedora para la piel..